Development Level

Tbio 14 | 11,178
Tclin 2 | 612
Tdark 2 | 6,569
Tchem 1 | 1,885

IMPC Phenotype

preweaning lethality, complete... 4 | 979
preweaning lethality, incomple... 3 | 499
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal pharyngeal arch morph... 1 | 8
abnormal rib morphology 1 | 10
decreased circulating triglyce... 1 | 79
embryonic growth retardation 1 | 106
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 96
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
vertebral fusion 1 | 23

Disease

group 3 medulloblastoma 14 | 4,002
ovarian cancer 13 | 8,297
osteosarcoma 12 | 7,766
psoriasis 11 | 6,514
Carcinoma 9 | 11,192
malignant mesothelioma 9 | 3,135
medulloblastoma, large-cell 9 | 6,086
non-small cell lung cancer 9 | 2,799
primitive neuroectodermal tumor 9 | 2,957
Breast cancer 7 | 3,469
Cancer 7 | 2,388
atypical teratoid / rhabdoid tumor 7 | 4,971
glioblastoma 7 | 5,635
adrenocortical carcinoma 6 | 1,385
lung adenocarcinoma 6 | 2,627
lung cancer 6 | 4,607
Kidney cancer 5 | 2,548
ependymoma 5 | 4,559
invasive ductal carcinoma 5 | 2,867
adult high grade glioma 4 | 3,701
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,204
Astrocytoma, Pilocytic 3 | 3,006
Colorectal Neoplasms 3 | 235
Lynch syndrome 3 | 34
ductal carcinoma in situ 3 | 1,686
nasopharyngeal carcinoma 3 | 1,024
Attention deficit hyperactivity disorder 2 | 272
Autosomal recessive predisposition 2 | 1,407
Endometrial cancer 2 | 301
Familial adenomatous polyposis 2 | 32
Multiple myeloma 2 | 1,296
Muscle hypotonia 2 | 562
Rothmund-Thomson syndrome 2 | 19
Waldenstrons macroglobulinemia 2 | 742
astrocytic glioma 2 | 2,530
colon cancer 2 | 1,428
dermatomyositis 2 | 941
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,872
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,902
juvenile dermatomyositis 2 | 1,147
pediatric high grade glioma 2 | 1,035
subependymal giant cell astrocytoma 2 | 2,230
Abdominal Pain 1 | 95
Acute lymphoid leukemia 1 | 25
Acute myeloid leukemia, disease 1 | 30
Adenocarcinoma of lung (disorder) 1 | 59
Anxiety 1 | 135
Anxiety disease 1 | 112
Ataxia telangiectasia 1 | 33
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Birthmark 1 | 35
Brachydactyly 1 | 154
Breast Neoplasms 1 | 423
Cafe-au-Lait Spots 1 | 37
Colorectal cancer 1 | 24
Death in early adulthood 1 | 24
Deglutition Disorders 1 | 128
DiGeorge syndrome 1 | 46
EAR, PATELLA, SHORT STATURE SYNDROME 1 | 7
Endometrial Neoplasms 1 | 54
Everted lower lip vermilion 1 | 54
Fatigue 1 | 176
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Hyperpigmented macules 1 | 41
Hypotrophic malar bone 1 | 129
Immunologic Deficiency Syndromes 1 | 110
Increased gastric cancer 1 | 21
Intermittent migraine headaches 1 | 66
Irritation - emotion 1 | 67
Lupus Erythematosus, Systemic 1 | 66
Lymphoma 1 | 75
Malar flattening 1 | 129
Malignant tumor of colon 1 | 19
Malignant tumor of ovary 1 | 25
Mammary Neoplasms 1 | 403
Mask-like facies 1 | 25
Meier-Gorlin syndrome 1 | 10
Meningeal Leukemia 1 | 7
Metastatic Breast Carcinoma 1 | 21
Microsatellite Instability 1 | 12
Migraine Disorders 1 | 74
Myoma 1 | 12
Nausea and vomiting 1 | 93
Open mouth 1 | 44
Protruding lower lip 1 | 54
Recurrent respiratory infections 1 | 138
Relative macrocephaly 1 | 12
Retinitis pigmentosa 3 1 | 16
Rhabdomyosarcoma 1 | 39
Sebaceous adenoma 1 | 26
Seckel syndrome 1 | 34
Uterine fibroid 1 | 28
Vaccinia 1 | 32
Velocardiofacial syndrome 1 | 46
Weight decreased 1 | 101
Xeroderma pigmentosum 1 | 42
Xeroderma pigmentosum group F 1 | 21
Xeroderma pigmentosum variant type 1 | 4
triple-A syndrome 1 | 17

Tissue

Blood and immune system 19 | 16,909
Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Liver and Pancreas 19 | 16,750
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Respiratory system 19 | 16,393
Skin and soft tissues 19 | 17,230
Urinary Tract 19 | 16,678
Cardiovascular System 18 | 15,192

Target Family

Enzyme 9 | 4,145
Non-IDG 9 | 12,091
Epigenetic 1 | 242

Compartment GO Term

Epsilon DNA polymerase complex 19 | 19
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA polymerase zeta catalytic subunit REV3L Tbio Enzyme -2.20108 158.5 41
DNA replication complex GINS protein SLD5 GINS4 Tbio Non-IDG -1.28555 18.6 59
Replication factor C subunit 1 RFC1 Tbio Non-IDG -1.43459 26.5 198
Exonuclease 1 EXO1 Tbio Enzyme -2.64302 437.0 263
DNA mismatch repair protein Msh6 MSH6 Tbio Epigenetic -2.72594 572.3 479
Cell division control protein 45 homolog CDC45 Tbio Non-IDG -2.10913 117.6 265
Chromatin accessibility complex protein 1 CHRAC1 Tdark Non-IDG -0.47787 3.02 120
Chromosome transmission fidelity protein 18 homolog CHTF18 Tbio Non-IDG -1.51235 35.5 138
DNA replication complex GINS protein PSF3 GINS3 Tbio Non-IDG -1.28801 20.4 42
Sister chromatid cohesion protein DCC1 DSCC1 Tbio Non-IDG -1.10259 11.9 144