Development Level

Tbio 435 | 11,651
Tdark 40 | 6,593
Tchem 29 | 1,388
Tclin 13 | 612

Collection

RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 40 | 979
preweaning lethality, incomple... 14 | 499
abnormal behavior 13 | 298
embryonic lethality prior to o... 13 | 239
abnormal embryo size 10 | 220
embryonic lethality prior to t... 10 | 278
decreased total body fat amoun... 8 | 207
hypoactivity 7 | 132
abnormal sleep behavior 6 | 70
decreased mean corpuscular hem... 6 | 50
hyperactivity 6 | 148
small superior vagus ganglion 6 | 74
abnormal heart morphology 5 | 162
decreased body weight 5 | 161
decreased bone mineral density 5 | 126
decreased mean corpuscular vol... 5 | 79
edema 5 | 59
increased bone mineral content 5 | 108
increased lean body mass 5 | 172
abnormal craniofacial morpholo... 4 | 33
abnormal lens morphology 4 | 81
abnormal seminal vesicle morph... 4 | 114
cataract 4 | 92
decreased circulating choleste... 4 | 93
decreased grip strength 4 | 116
embryonic growth retardation 4 | 106
enlarged heart 4 | 210
hydrometra 4 | 53
increased fasted circulating g... 4 | 76
increased or absent threshold ... 4 | 101
increased startle reflex 4 | 112
prolonged QT interval 4 | 38
abnormal behavioral response t... 3 | 66
abnormal bone structure 3 | 187
abnormal gait 3 | 69
abnormal hindbrain morphology 3 | 10
abnormal kidney morphology 3 | 65
abnormal neural tube closure 3 | 46
abnormal retina morphology 3 | 71
abnormal vibrissa morphology 3 | 25
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating glucose ... 3 | 126
decreased circulating insulin ... 3 | 76
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased prepulse inhibition 3 | 82
improved glucose tolerance 3 | 79
increased circulating HDL chol... 3 | 80
increased circulating alkaline... 3 | 122
increased circulating potassiu... 3 | 29
increased leukocyte cell numbe... 3 | 47
increased mean corpuscular vol... 3 | 92
increased neutrophil cell numb... 3 | 46
limb grasping 3 | 41
prolonged ST segment 3 | 36
short tibia 3 | 97
abnormal body wall morphology 2 | 9
abnormal cecum morphology 2 | 7
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal midbrain morphology 2 | 10
abnormal skin morphology 2 | 50
abnormal vertebrae morphology 2 | 18
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
decreased circulating alkaline... 2 | 46
decreased circulating chloride... 2 | 30
decreased circulating free fat... 2 | 31
decreased circulating potassiu... 2 | 20
decreased circulating sodium l... 2 | 22
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased lean body mass 2 | 135
decreased red blood cell distr... 2 | 41
enlarged cecum 2 | 5
enlarged epididymis 2 | 31
enlarged kidney 2 | 14
enlarged spleen 2 | 41
increased bone mineral density 2 | 72
increased circulating calcium ... 2 | 34
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating iron lev... 2 | 30
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased circulating total pr... 2 | 28
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased heart weight 2 | 62
increased lymphocyte cell numb... 2 | 32
increased mean corpuscular hem... 2 | 96
increased red blood cell distr... 2 | 34
persistence of hyaloid vascula... 2 | 33
prenatal lethality 2 | 28
prenatal lethality prior to he... 2 | 87
prolonged PR interval 2 | 15
thrombocytosis 2 | 27
tremors 2 | 39
decreased mean corpuscular hem... 1 | 31

Disease

Carcinoma 288 | 11,493
ovarian cancer 269 | 8,520
psoriasis 216 | 6,694
osteosarcoma 208 | 7,950
medulloblastoma, large-cell 189 | 6,241
glioblastoma 184 | 5,792
Cancer 142 | 2,499
atypical teratoid / rhabdoid tumor 142 | 5,112
lung cancer 125 | 4,740
ependymoma 121 | 4,679
diabetes mellitus 108 | 1,728
Astrocytoma, Pilocytic 94 | 3,081
adult high grade glioma 94 | 3,801
tuberculosis 94 | 2,010
intraductal papillary-mucinous neoplasm (IPMN) 87 | 3,291
Breast cancer 83 | 3,578
dermatomyositis 82 | 966
invasive ductal carcinoma 82 | 2,951
lung carcinoma 80 | 2,843
non-small cell lung cancer 80 | 2,890
group 3 medulloblastoma 79 | 4,104
Rheumatoid arthritis 78 | 1,191
malignant mesothelioma 78 | 3,232
oligodendroglioma 76 | 2,850
pancreatic cancer 76 | 2,398
intraductal papillary-mucinous adenoma (IPMA) 75 | 2,955
Ankylosing spondylitis 73 | 140
astrocytic glioma 73 | 2,597
subependymal giant cell astrocytoma 72 | 2,287
Hypersensitivity reaction type II disease 71 | 253
Behcet's disease 70 | 89
intraductal papillary-mucinous carcinoma (IPMC) 69 | 2,989
Arthritis 68 | 290
pancreatic ductal adenocarcinoma liver metastasis 66 | 1,962
Kidney cancer 65 | 2,613
lung adenocarcinoma 64 | 2,716
Juvenile rheumatoid arthritis 61 | 111
Multiple myeloma 61 | 1,332
group 4 medulloblastoma 61 | 1,855
primitive neuroectodermal tumor 61 | 3,035
Acquired immunodeficiency syndrome 59 | 197
Pick disease 59 | 1,894
Uveitis 59 | 103
Human immunodeficiency virus infectious disease 57 | 138
interstitial cystitis 57 | 2,312
juvenile dermatomyositis 57 | 1,187
Herpes zoster 56 | 68
breast carcinoma 55 | 1,638
Stevens-Johnson syndrome 54 | 92
Psoriatic arthritis 52 | 86
ulcerative colitis 51 | 1,819
pediatric high grade glioma 46 | 1,064
ductal carcinoma in situ 45 | 1,745
Autosomal recessive predisposition 43 | 1,442
primary pancreatic ductal adenocarcinoma 43 | 1,109
astrocytoma 42 | 1,146
pituitary cancer 42 | 1,972
Multiple Sclerosis 41 | 540
Dermatitis 40 | 157
acute quadriplegic myopathy 40 | 1,158
cystic fibrosis 38 | 1,696
adrenocortical carcinoma 37 | 1,428
Anemia 36 | 365
Behcet's syndrome 36 | 50
Synovitis 36 | 78
esophageal adenocarcinoma 36 | 737
Congenital adrenal hyperplasia 35 | 73
Liver disease 35 | 237
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
Schizophrenia 34 | 1,160
active Crohn's disease 34 | 922
cutaneous lupus erythematosus 34 | 1,057
Hepatitis B 32 | 108
Kidney disease 32 | 430
primary Sjogren syndrome 32 | 735
Neurodegenerative disease 30 | 414
Alzheimer's disease 29 | 658
Waldenstrons macroglobulinemia 29 | 765
colon cancer 29 | 1,478
Down syndrome 28 | 499
gastric carcinoma 28 | 807
Leprosy 27 | 73
spina bifida 27 | 1,074
Duchenne muscular dystrophy 26 | 601
Hemochromatosis 26 | 54
non primary Sjogren syndrome sicca 26 | 891
Skin disease 23 | 66
aldosterone-producing adenoma 23 | 665
Liver Cirrhosis, Experimental 22 | 769
active ulcerative colitis 22 | 764
acute myeloid leukemia 22 | 783
fibroadenoma 22 | 559
mucosa-associated lymphoid tissue lymphoma 22 | 484
progressive supranuclear palsy 22 | 676
Birdshot chorioretinopathy 21 | 23
pancreatic carcinoma 21 | 562

Tissue

Endocrine System 436 | 18,159
Digestive Tract 434 | 17,369
Female tissues 433 | 17,400
Skin and soft tissues 433 | 17,230
Male tissues 432 | 17,142
Blood and immune system 431 | 16,909
Respiratory system 430 | 16,393
Liver and Pancreas 429 | 16,750
Nervous System 427 | 16,725
Urinary Tract 427 | 16,678
Cardiovascular System 412 | 15,192

Target Family

Non-IDG 365 | 12,091
Enzyme 92 | 4,145
Kinase 21 | 634
Transporter 21 | 473
Ion Channel 12 | 344
GPCR 3 | 408
Transcription Factor 3 | 1,400

Compartment GO Term

Endosome membrane 517 | 517
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
UPF0577 protein KIAA1324 KIAA1324 Tbio Non-IDG -1.30268 19.8 137
CMRF35-like molecule 9 CD300LG Tdark Non-IDG -0.92828 10.3 49
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0