Development Level

Tbio 702 | 11,651
Tchem 93 | 1,388
Tdark 84 | 6,593
Tclin 52 | 612

Collection

GPCR: IDG Consortium (Complete... 2 | 25
Kinase: IDG Consortium (Comple... 2 | 37
Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 60 | 979
preweaning lethality, incomple... 27 | 499
abnormal behavior 23 | 298
embryonic lethality prior to t... 18 | 278
embryonic lethality prior to o... 17 | 239
decreased total body fat amoun... 15 | 207
abnormal embryo size 14 | 220
hypoactivity 13 | 132
increased circulating alkaline... 11 | 122
decreased mean corpuscular hem... 10 | 50
increased lean body mass 10 | 172
abnormal bone structure 9 | 187
abnormal sleep behavior 9 | 70
decreased body weight 9 | 161
decreased grip strength 9 | 116
increased bone mineral content 9 | 108
decreased circulating glucose ... 8 | 126
decreased prepulse inhibition 8 | 82
enlarged heart 8 | 210
hyperactivity 8 | 148
increased bone mineral density 8 | 72
increased startle reflex 8 | 112
short tibia 8 | 97
abnormal heart morphology 7 | 162
abnormal seminal vesicle morph... 7 | 114
cataract 7 | 92
decreased bone mineral content 7 | 151
decreased bone mineral density 7 | 126
embryonic growth retardation 7 | 106
increased fasted circulating g... 7 | 76
increased mean corpuscular vol... 7 | 92
increased total body fat amoun... 7 | 134
small superior vagus ganglion 7 | 74
abnormal behavioral response t... 6 | 66
abnormal lens morphology 6 | 81
decreased circulating choleste... 6 | 93
decreased lymphocyte cell numb... 6 | 83
decreased mean corpuscular vol... 6 | 79
increased circulating HDL chol... 6 | 80
increased circulating choleste... 6 | 66
increased heart weight 6 | 62
increased or absent threshold ... 6 | 101
limb grasping 6 | 41
abnormal gait 5 | 69
abnormal kidney morphology 5 | 65
abnormal retina morphology 5 | 71
cardiovascular system phenotyp... 5 | 36
decreased circulating HDL chol... 5 | 68
decreased circulating insulin ... 5 | 76
decreased lean body mass 5 | 135
decreased leukocyte cell numbe... 5 | 73
decreased vertical activity 5 | 208
edema 5 | 59
hydrometra 5 | 53
impaired glucose tolerance 5 | 75
improved glucose tolerance 5 | 79
increased neutrophil cell numb... 5 | 46
thrombocytosis 5 | 27
abnormal craniofacial morpholo... 4 | 33
abnormal neural tube closure 4 | 46
abnormal vibrissa morphology 4 | 25
decreased circulating LDL chol... 4 | 38
decreased circulating alkaline... 4 | 46
increased body length 4 | 32
increased circulating LDL chol... 4 | 13
increased circulating free fat... 4 | 20
increased circulating serum al... 4 | 22
increased circulating sodium l... 4 | 71
increased circulating triglyce... 4 | 42
increased leukocyte cell numbe... 4 | 47
increased mean corpuscular hem... 4 | 96
prenatal lethality 4 | 28
prolonged QT interval 4 | 38
prolonged ST segment 4 | 36
tremors 4 | 39
abnormal hindbrain morphology 3 | 10
abnormal pericardium morpholog... 3 | 26
abnormal vertebrae morphology 3 | 18
decreased blood urea nitrogen ... 3 | 51
decreased circulating bilirubi... 3 | 19
decreased circulating chloride... 3 | 30
decreased circulating serum al... 3 | 82
decreased circulating triglyce... 3 | 79
decreased fasted circulating g... 3 | 65
decreased heart weight 3 | 27
decreased hemoglobin content 3 | 68
decreased large unstained cell... 3 | 11
decreased startle reflex 3 | 75
decreased total retina thickne... 3 | 17
enlarged spleen 3 | 41
increased body weight 3 | 25
increased circulating calcium ... 3 | 34
increased circulating iron lev... 3 | 30
increased circulating phosphat... 3 | 26
increased circulating potassiu... 3 | 29
increased circulating total pr... 3 | 28
increased hematocrit 3 | 46
increased monocyte cell number 3 | 63
increased red blood cell distr... 3 | 34
pallor 3 | 34

Disease

Carcinoma 576 | 11,493
ovarian cancer 504 | 8,520
osteosarcoma 419 | 7,950
psoriasis 386 | 6,694
glioblastoma 345 | 5,792
medulloblastoma, large-cell 344 | 6,241
lung cancer 265 | 4,740
Cancer 260 | 2,499
atypical teratoid / rhabdoid tumor 260 | 5,112
ependymoma 226 | 4,679
adult high grade glioma 190 | 3,801
diabetes mellitus 186 | 1,728
malignant mesothelioma 186 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 182 | 3,291
Astrocytoma, Pilocytic 181 | 3,081
tuberculosis 171 | 2,010
invasive ductal carcinoma 170 | 2,951
Breast cancer 169 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 160 | 2,955
lung carcinoma 159 | 2,843
non-small cell lung cancer 157 | 2,890
oligodendroglioma 152 | 2,850
Kidney cancer 149 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 147 | 2,989
group 3 medulloblastoma 146 | 4,104
pancreatic cancer 144 | 2,398
subependymal giant cell astrocytoma 144 | 2,287
lung adenocarcinoma 141 | 2,716
astrocytic glioma 137 | 2,597
Rheumatoid arthritis 127 | 1,191
primitive neuroectodermal tumor 127 | 3,035
interstitial cystitis 120 | 2,312
Pick disease 118 | 1,894
group 4 medulloblastoma 116 | 1,855
dermatomyositis 112 | 966
pancreatic ductal adenocarcinoma liver metastasis 112 | 1,962
ulcerative colitis 111 | 1,819
Multiple myeloma 101 | 1,332
juvenile dermatomyositis 100 | 1,187
Autosomal recessive predisposition 96 | 1,442
Arthritis 95 | 290
ductal carcinoma in situ 94 | 1,745
Hypersensitivity reaction type II disease 93 | 253
Schizophrenia 93 | 1,160
breast carcinoma 93 | 1,638
cystic fibrosis 92 | 1,696
pituitary cancer 92 | 1,972
astrocytoma 79 | 1,146
cutaneous lupus erythematosus 79 | 1,057
Ankylosing spondylitis 76 | 140
Multiple Sclerosis 76 | 540
primary pancreatic ductal adenocarcinoma 76 | 1,109
Alzheimer's disease 71 | 658
Behcet's disease 71 | 89
pediatric high grade glioma 69 | 1,064
Acquired immunodeficiency syndrome 68 | 197
acute quadriplegic myopathy 68 | 1,158
adrenocortical carcinoma 68 | 1,428
colon cancer 68 | 1,478
Juvenile rheumatoid arthritis 66 | 111
Neurodegenerative disease 66 | 414
Human immunodeficiency virus infectious disease 65 | 138
primary Sjogren syndrome 64 | 735
Kidney disease 63 | 430
Uveitis 63 | 103
Intellectual disability 62 | 1,016
Liver Cirrhosis, Experimental 61 | 769
esophageal adenocarcinoma 61 | 737
active Crohn's disease 60 | 922
Herpes zoster 58 | 68
Bipolar Disorder 57 | 666
Anemia 56 | 365
spina bifida 56 | 1,074
Stevens-Johnson syndrome 55 | 92
gastric carcinoma 55 | 807
Epilepsy 54 | 792
Psoriatic arthritis 54 | 86
Liver disease 53 | 237
Down syndrome 51 | 499
Obesity 50 | 678
Dermatitis 49 | 157
Duchenne muscular dystrophy 48 | 601
non primary Sjogren syndrome sicca 47 | 891
Melanoma 45 | 711
Seizures 45 | 596
nasopharyngeal carcinoma 45 | 1,058
Prostatic Neoplasms 44 | 495
Waldenstrons macroglobulinemia 43 | 765
active ulcerative colitis 43 | 764
acute myeloid leukemia 42 | 783
Dull intelligence 41 | 645
Low intelligence 41 | 645
Mental Retardation 41 | 645
Mental deficiency 41 | 645
Poor school performance 41 | 645
Congenital adrenal hyperplasia 39 | 73
Hypertension 39 | 396
Synovitis 39 | 78
pancreatic carcinoma 39 | 562
Depressive disorder 38 | 409

Tissue

Endocrine System 843 | 18,159
Digestive Tract 840 | 17,369
Female tissues 834 | 17,400
Skin and soft tissues 830 | 17,230
Male tissues 828 | 17,142
Liver and Pancreas 826 | 16,750
Urinary Tract 825 | 16,678
Blood and immune system 824 | 16,909
Respiratory system 820 | 16,393
Nervous System 818 | 16,725
Cardiovascular System 777 | 15,192

Target Family

Non-IDG 630 | 12,091
Enzyme 169 | 4,145
Kinase 52 | 634
Transporter 31 | 473
GPCR 28 | 408
Ion Channel 15 | 344
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
oGPCR 1 | 421

Compartment GO Term

Endosome 931 | 931
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
HLA class I histocompatibility antigen, A-25 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
UPF0577 protein KIAA1324 KIAA1324 Tbio Non-IDG -1.30268 19.8 137
CMRF35-like molecule 9 CD300LG Tdark Non-IDG -0.92828 10.3 49
HLA class I histocompatibility antigen, B-51 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0