Development Level

Tbio 612 | 10,625
Tchem 111 | 1,890
Tdark 92 | 7,003
Tclin 42 | 602

Collection

Eligible Kinase Proteins 3 | 134
Eligible Ion Channel Proteins 1 | 117
Eligible non-olfactory GPCR Proteins 1 | 143

IMPC Term

preweaning lethality, complete... 36 | 633
decreased total body fat amoun... 15 | 186
preweaning lethality, incomple... 14 | 260
abnormal behavior 13 | 226
increased circulating alkaline... 13 | 119
decreased grip strength 12 | 123
decreased lean body mass 9 | 195
embryonic lethality prior to t... 9 | 187
decreased body length 8 | 108
decreased bone mineral content 8 | 157
embryonic lethality prior to o... 8 | 148
hypoactivity 8 | 89
increased or absent threshold ... 8 | 128
decreased bone mineral density 7 | 126
decreased prepulse inhibition 7 | 52
increased bone mineral content 7 | 92
increased circulating HDL chol... 7 | 63
increased sacral vertebrae num... 7 | 62
abnormal retinal pigmentation 6 | 61
decreased body weight 6 | 174
decreased lumbar vertebrae num... 6 | 62
decreased mean corpuscular hem... 6 | 34
decreased rib number 6 | 59
increased bone mineral density 6 | 52
abnormal kidney morphology 5 | 30
abnormal lens morphology 5 | 73
abnormal retina morphology 5 | 100
abnormal sleep behavior 5 | 63
decreased circulating glucose ... 5 | 121
decreased circulating triglyce... 5 | 83
decreased mean corpuscular vol... 5 | 50
decreased monocyte cell number 5 | 28
increased circulating LDL chol... 5 | 15
increased circulating choleste... 5 | 53
increased fasted circulating g... 5 | 68
increased lean body mass 5 | 107
increased mean corpuscular hem... 5 | 93
increased mean corpuscular vol... 5 | 91
limb grasping 5 | 35
abnormal bone structure 4 | 131
cardiovascular system phenotyp... 4 | 35
decreased NK T cell number 4 | 28
decreased circulating HDL chol... 4 | 77
decreased circulating LDL chol... 4 | 37
decreased circulating insulin ... 4 | 75
decreased circulating serum al... 4 | 79
decreased leukocyte cell numbe... 4 | 54
enlarged heart 4 | 111
hyperactivity 4 | 108
increased B cell number 4 | 23
increased blood urea nitrogen ... 4 | 44
increased leukocyte cell numbe... 4 | 37
short tibia 4 | 82
thrombocytosis 4 | 23
abnormal QRS complex 3 | 25
abnormal epididymis morphology 3 | 31
abnormal gait 3 | 51
decreased Ly6C low monocyte nu... 3 | 23
decreased circulating alkaline... 3 | 41
decreased circulating bilirubi... 3 | 14
decreased circulating choleste... 3 | 85
decreased heart weight 3 | 44
decreased total retina thickne... 3 | 20
enlarged epididymis 3 | 27
impaired glucose tolerance 3 | 52
improved glucose tolerance 3 | 56
increased T cell number 3 | 15
increased body weight 3 | 42
increased circulating free fat... 3 | 17
increased circulating potassiu... 3 | 31
increased circulating serum al... 3 | 25
increased circulating sodium l... 3 | 71
increased exploration in new e... 3 | 56
increased grip strength 3 | 83
increased hematocrit 3 | 36
increased hemoglobin content 3 | 45
increased mature B cell number 3 | 12
increased rib number 3 | 41
polydactyly 3 | 22
straub tail 3 | 26
abnormal behavioral response t... 2 | 52
abnormal body wall morphology 2 | 7
abnormal embryo size 2 | 112
abnormal heart morphology 2 | 51
abnormal retinal inner nuclear... 2 | 5
abnormal vertebrae morphology 2 | 14
abnormal vibrissa morphology 2 | 17
decreased caudal vertebrae num... 2 | 49
decreased circulating potassiu... 2 | 17
decreased circulating sodium l... 2 | 18
decreased fasted circulating g... 2 | 49
decreased hemoglobin content 2 | 53
enlarged spleen 2 | 26
increased NK cell number 2 | 19
increased circulating calcium ... 2 | 32
increased circulating chloride... 2 | 43
increased circulating iron lev... 2 | 25
increased erythrocyte cell num... 2 | 26
prenatal lethality prior to he... 2 | 64
thrombocytopenia 2 | 46

Disease

ovarian cancer 470 | 8,484
osteosarcoma 386 | 7,933
psoriasis 363 | 6,685
medulloblastoma, large-cell 319 | 6,234
glioblastoma 301 | 5,572
lung cancer 234 | 4,466
Cancer 229 | 2,346
atypical teratoid / rhabdoid tumor 206 | 4,369
diabetes mellitus 169 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 169 | 3,289
malignant mesothelioma 163 | 3,162
pilocytic astrocytoma 163 | 3,086
invasive ductal carcinoma 156 | 2,950
lung carcinoma 149 | 2,844
intraductal papillary-mucinous adenoma (IPMA) 148 | 2,956
non-small cell lung cancer 143 | 2,798
pediatric high grade glioma 140 | 2,712
intraductal papillary-mucinous carcinoma (IPMC) 138 | 2,988
oligodendroglioma 138 | 2,849
Breast cancer 137 | 3,094
lung adenocarcinoma 134 | 2,713
subependymal giant cell astrocytoma 134 | 2,287
pancreatic cancer 127 | 2,300
Rheumatoid Arthritis 121 | 1,160
ependymoma 121 | 2,514
ulcerative colitis 117 | 2,087
primitive neuroectodermal tumor 116 | 3,031
tuberculosis 112 | 1,557
Pick disease 111 | 1,893
interstitial cystitis 109 | 2,299
Carcinoma 105 | 2,147
astrocytic glioma 103 | 2,241
adult high grade glioma 99 | 2,148
group 4 medulloblastoma 96 | 1,875
Multiple myeloma 95 | 1,327
pancreatic ductal adenocarcinoma liver metastasis 95 | 1,795
astrocytoma 94 | 1,493
juvenile dermatomyositis 91 | 1,189
cystic fibrosis 89 | 1,665
Hypersensitivity reaction type II disease 86 | 235
ductal carcinoma in situ 86 | 1,745
Arthritis 85 | 248
breast carcinoma 83 | 1,614
pituitary cancer 80 | 1,972
primary pancreatic ductal adenocarcinoma 79 | 1,271
Ankylosing spondylitis 75 | 138
dermatomyositis 73 | 933
cutaneous lupus erythematosus 71 | 1,056
medulloblastoma 71 | 1,524
posterior fossa group A ependymoma 70 | 1,511
Multiple Sclerosis 69 | 498
Alzheimer's disease 68 | 644
Acquired immunodeficiency syndrome 65 | 164
acute quadriplegic myopathy 64 | 1,157
Juvenile rheumatoid arthritis 63 | 104
Uveitis 63 | 103
adrenocortical carcinoma 62 | 1,427
colon cancer 62 | 1,475
sonic hedgehog group medulloblastoma 61 | 1,482
Kidney disease 60 | 396
group 3 medulloblastoma 60 | 2,254
primary Sjogren syndrome 60 | 789
Neurodegenerative disease 58 | 383
Behcet's disease 57 | 74
posterior fossa group B ependymoma 56 | 1,530
esophageal adenocarcinoma 55 | 737
Psoriatic arthritis 53 | 83
atypical teratoid/rhabdoid tumor 53 | 1,095
gastric carcinoma 53 | 832
spina bifida 53 | 1,064
active Crohn's disease 52 | 918
Liver disease 51 | 219
Down syndrome 49 | 548
nasopharyngeal carcinoma 43 | 1,056
Anemia 42 | 252
Duchenne muscular dystrophy 42 | 602
Obesity 42 | 616
Stevens-Johnson syndrome 42 | 78
Prostatic Neoplasms 41 | 471
non primary Sjogren syndrome sicca 41 | 840
tuberculosis and treatment for 6 months 41 | 686
Waldenstrons macroglobulinemia 40 | 765
Congenital adrenal hyperplasia 39 | 74
acute myeloid leukemia 38 | 780
IGA Glomerulonephritis 36 | 454
Retinal vasculitis 36 | 36
Takayasu's arteritis 36 | 52
pancreatic carcinoma 36 | 567
Asthma 34 | 349
Hepatitis B 34 | 103
Leprosy 34 | 77
aldosterone-producing adenoma 34 | 664
mucosa-associated lymphoid tissue lymphoma 34 | 480
progressive supranuclear palsy 34 | 674
Atherosclerosis 33 | 275
Coronary artery disease 33 | 240
Schizophrenia 33 | 501
fibroadenoma 33 | 557
Amyotrophic Lateral Sclerosis 32 | 431
Parkinson's disease 32 | 364

Tissue

Nervous System 782 | 18,561
Digestive Tract 781 | 18,473
Endocrine System 781 | 18,512
Urinary Tract 781 | 18,444
Female tissues 780 | 18,647
Liver and Pancreas 780 | 18,136
Male tissues 779 | 17,969
Blood and immune system 776 | 17,995
Respiratory system 776 | 17,484
Cardiovascular System 775 | 17,958
Skin and soft tissues 768 | 18,115

Target Family

Non-IDG 585 | 11,971
Enzyme 152 | 4,146
Kinase 47 | 634
Transporter 29 | 473
GPCR 26 | 406
Ion Channel 14 | 341
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
oGPCR 1 | 421

Compartment GO Term

Endosome 857 | 857
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -3.60614 4042.7 585
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788