Development Level

Tbio 456 | 11,445
Tchem 49 | 1,598
Tdark 43 | 6,588
Tclin 17 | 613

Collection

RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 41 | 979
preweaning lethality, incomple... 18 | 499
abnormal behavior 16 | 298
embryonic lethality prior to o... 13 | 239
abnormal embryo size 10 | 220
embryonic lethality prior to t... 10 | 278
hypoactivity 10 | 132
decreased total body fat amoun... 9 | 207
decreased mean corpuscular hem... 8 | 50
abnormal sleep behavior 7 | 70
hyperactivity 7 | 148
increased bone mineral content 7 | 108
short tibia 7 | 97
small superior vagus ganglion 7 | 74
abnormal heart morphology 6 | 162
increased lean body mass 6 | 172
increased or absent threshold ... 6 | 101
abnormal seminal vesicle morph... 5 | 114
decreased body weight 5 | 161
decreased bone mineral density 5 | 126
decreased grip strength 5 | 116
decreased mean corpuscular vol... 5 | 79
decreased prepulse inhibition 5 | 82
edema 5 | 59
enlarged heart 5 | 210
increased startle reflex 5 | 112
abnormal behavioral response t... 4 | 66
abnormal craniofacial morpholo... 4 | 33
abnormal kidney morphology 4 | 65
abnormal lens morphology 4 | 81
abnormal retina morphology 4 | 71
cataract 4 | 92
decreased circulating choleste... 4 | 93
decreased circulating glucose ... 4 | 126
decreased circulating insulin ... 4 | 76
embryonic growth retardation 4 | 106
hydrometra 4 | 53
increased bone mineral density 4 | 72
increased circulating HDL chol... 4 | 80
increased circulating alkaline... 4 | 122
increased fasted circulating g... 4 | 76
increased neutrophil cell numb... 4 | 46
limb grasping 4 | 41
prolonged QT interval 4 | 38
abnormal bone structure 3 | 187
abnormal gait 3 | 69
abnormal hindbrain morphology 3 | 10
abnormal neural tube closure 3 | 46
abnormal vibrissa morphology 3 | 25
cardiovascular system phenotyp... 3 | 36
decreased bone mineral content 3 | 151
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased heart weight 3 | 27
decreased lean body mass 3 | 135
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased red blood cell distr... 3 | 41
enlarged spleen 3 | 41
improved glucose tolerance 3 | 79
increased circulating potassiu... 3 | 29
increased heart weight 3 | 62
increased leukocyte cell numbe... 3 | 47
increased mean corpuscular vol... 3 | 92
increased red blood cell distr... 3 | 34
prenatal lethality 3 | 28
prolonged ST segment 3 | 36
abnormal body wall morphology 2 | 9
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal skin morphology 2 | 50
abnormal vertebrae morphology 2 | 18
absent startle reflex 2 | 24
decreased circulating alkaline... 2 | 46
decreased circulating bilirubi... 2 | 19
decreased circulating free fat... 2 | 31
decreased circulating potassiu... 2 | 20
decreased circulating serum al... 2 | 82
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased hemoglobin content 2 | 68
decreased startle reflex 2 | 75
decreased total retina thickne... 2 | 17
enlarged kidney 2 | 14
impaired glucose tolerance 2 | 75
increased body length 2 | 32
increased cardiac muscle contr... 2 | 8
increased circulating calcium ... 2 | 34
increased circulating chloride... 2 | 41
increased circulating choleste... 2 | 66
increased circulating iron lev... 2 | 30
increased circulating serum al... 2 | 22
increased circulating sodium l... 2 | 71
increased circulating total pr... 2 | 28
increased eosinophil cell numb... 2 | 11
increased mean corpuscular hem... 2 | 96
persistence of hyaloid vascula... 2 | 33
prenatal lethality prior to he... 2 | 87
thrombocytosis 2 | 27
tremors 2 | 39

Disease

Carcinoma 323 | 11,493
ovarian cancer 299 | 8,520
psoriasis 233 | 6,694
osteosarcoma 228 | 7,950
medulloblastoma, large-cell 206 | 6,241
glioblastoma 200 | 5,792
Cancer 154 | 2,499
atypical teratoid / rhabdoid tumor 153 | 5,112
lung cancer 138 | 4,740
ependymoma 127 | 4,679
diabetes mellitus 118 | 1,728
adult high grade glioma 103 | 3,801
tuberculosis 101 | 2,010
Astrocytoma, Pilocytic 100 | 3,081
intraductal papillary-mucinous neoplasm (IPMN) 100 | 3,291
Breast cancer 92 | 3,578
invasive ductal carcinoma 91 | 2,951
non-small cell lung cancer 91 | 2,890
lung carcinoma 90 | 2,843
group 3 medulloblastoma 89 | 4,104
malignant mesothelioma 89 | 3,232
dermatomyositis 87 | 966
intraductal papillary-mucinous adenoma (IPMA) 85 | 2,955
pancreatic cancer 84 | 2,398
Rheumatoid arthritis 83 | 1,191
oligodendroglioma 82 | 2,850
subependymal giant cell astrocytoma 80 | 2,287
astrocytic glioma 79 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 78 | 2,989
Arthritis 76 | 290
Ankylosing spondylitis 74 | 140
Hypersensitivity reaction type II disease 72 | 253
Kidney cancer 72 | 2,613
lung adenocarcinoma 72 | 2,716
Behcet's disease 70 | 89
Pick disease 69 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 69 | 1,962
Multiple myeloma 66 | 1,332
group 4 medulloblastoma 65 | 1,855
primitive neuroectodermal tumor 65 | 3,035
interstitial cystitis 62 | 2,312
juvenile dermatomyositis 62 | 1,187
Juvenile rheumatoid arthritis 61 | 111
Acquired immunodeficiency syndrome 60 | 197
Uveitis 59 | 103
ulcerative colitis 59 | 1,819
breast carcinoma 58 | 1,638
Human immunodeficiency virus infectious disease 57 | 138
Herpes zoster 56 | 68
Stevens-Johnson syndrome 54 | 92
Autosomal recessive predisposition 53 | 1,442
Psoriatic arthritis 53 | 86
ductal carcinoma in situ 50 | 1,745
acute quadriplegic myopathy 47 | 1,158
pediatric high grade glioma 47 | 1,064
pituitary cancer 47 | 1,972
primary pancreatic ductal adenocarcinoma 47 | 1,109
cystic fibrosis 45 | 1,696
Multiple Sclerosis 44 | 540
astrocytoma 43 | 1,146
Anemia 41 | 365
Schizophrenia 41 | 1,160
cutaneous lupus erythematosus 41 | 1,057
Dermatitis 40 | 157
adrenocortical carcinoma 40 | 1,428
esophageal adenocarcinoma 40 | 737
Behcet's syndrome 37 | 50
Kidney disease 36 | 430
Liver disease 36 | 237
Neurodegenerative disease 36 | 414
Synovitis 36 | 78
Takayasu's arteritis 36 | 53
active Crohn's disease 36 | 922
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
colon cancer 35 | 1,478
drug-induced hepatitis 35 | 44
primary Sjogren syndrome 35 | 735
Alzheimer's disease 34 | 658
Hepatitis B 32 | 108
Waldenstrons macroglobulinemia 31 | 765
gastric carcinoma 31 | 807
spina bifida 30 | 1,074
Down syndrome 29 | 499
Duchenne muscular dystrophy 29 | 601
Liver Cirrhosis, Experimental 29 | 769
non primary Sjogren syndrome sicca 29 | 891
Leprosy 28 | 73
Epilepsy 26 | 792
Hemochromatosis 26 | 54
Intellectual disability 26 | 1,016
mucosa-associated lymphoid tissue lymphoma 25 | 484
acute myeloid leukemia 24 | 783
progressive supranuclear palsy 24 | 676
Obesity 23 | 678
active ulcerative colitis 23 | 764
aldosterone-producing adenoma 23 | 665
fibroadenoma 23 | 559

Tissue

Endocrine System 484 | 18,159
Digestive Tract 482 | 17,369
Female tissues 481 | 17,400
Skin and soft tissues 480 | 17,230
Blood and immune system 477 | 16,909
Male tissues 477 | 17,142
Respiratory system 477 | 16,393
Liver and Pancreas 474 | 16,750
Urinary Tract 472 | 16,678
Nervous System 471 | 16,725
Cardiovascular System 453 | 15,192

Target Family

Non-IDG 399 | 12,091
Enzyme 104 | 4,145
Kinase 23 | 634
Transporter 21 | 473
Ion Channel 12 | 344
GPCR 3 | 408
Transcription Factor 3 | 1,400

Compartment GO Term

Endosomal part 565 | 565
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Epidermal growth factor receptor EGFR Tclin Kinase -4.02650 10013.1 6418