Development Level

Tbio 35 | 11,445
Tchem 8 | 1,598
Tdark 4 | 6,588

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to t... 3 | 278
decreased circulating insulin ... 2 | 76
decreased red blood cell distr... 2 | 41
embryonic lethality prior to o... 2 | 239
increased grip strength 2 | 41
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal vibrissa morphology 1 | 25
absent spleen 1 | 3
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating triglyce... 1 | 42
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

Carcinoma 32 | 11,493
osteosarcoma 25 | 7,950
lung cancer 19 | 4,740
ovarian cancer 19 | 8,520
psoriasis 19 | 6,694
Cancer 16 | 2,499
medulloblastoma, large-cell 14 | 6,241
atypical teratoid / rhabdoid tumor 13 | 5,112
glioblastoma 13 | 5,792
Breast cancer 10 | 3,578
ependymoma 10 | 4,679
Multiple myeloma 9 | 1,332
group 3 medulloblastoma 9 | 4,104
Alzheimer's disease 8 | 658
Schizophrenia 8 | 1,160
diabetes mellitus 8 | 1,728
malignant mesothelioma 8 | 3,232
oligodendroglioma 8 | 2,850
Kidney cancer 7 | 2,613
Pick disease 7 | 1,894
Vascular disease 7 | 319
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
Intellectual disability 6 | 1,016
Neurodegenerative disease 6 | 414
Rheumatoid arthritis 6 | 1,191
hepatocellular carcinoma 6 | 547
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
tuberculosis 6 | 2,010
Bipolar Disorder 5 | 666
Obesity 5 | 678
Parkinson's disease 5 | 392
acute myeloid leukemia 5 | 783
lung adenocarcinoma 5 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
Deglutition Disorders 4 | 132
Depressive disorder 4 | 409
Liver Cirrhosis, Experimental 4 | 769
Mental Depression 4 | 333
Movement Disorders 4 | 55
Pontocerebellar hypoplasia 4 | 36
Toxic encephalopathy 4 | 141
acute quadriplegic myopathy 4 | 1,158
adult high grade glioma 4 | 3,801
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
group 4 medulloblastoma 4 | 1,855
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
primitive neuroectodermal tumor 4 | 3,035
spina bifida 4 | 1,074
subependymal giant cell astrocytoma 4 | 2,287
Amyotrophic lateral sclerosis 3 | 451
Asbestosis 3 | 20
Autosomal recessive predisposition 3 | 1,442
Fatty Liver 3 | 70
Fatty liver disease 3 | 103
Gaucher disease type 1 3 | 180
Hyperreflexia 3 | 209
Microcephaly 3 | 166
Pontocerebellar Hypoplasia Type 2 3 | 5
Vision Disorders 3 | 6
Wilms Tumor 3 | 28
astrocytoma 3 | 1,146
invasive ductal carcinoma 3 | 2,951
medulloblastoma 3 | 720
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Delayed speech and language development 2 | 112
Down syndrome 2 | 499
Epilepsy 2 | 792
Eye disease 2 | 62
Heart disease 2 | 306
Inflammatory bowel disease 2 | 151
Kidney disease 2 | 430
Language Delay 2 | 112
Multiple Sclerosis 2 | 540
Muscle Spasticity 2 | 195
Physical aggression 2 | 76
Prostate cancer 2 | 175
Prostatic Neoplasms 2 | 495
Psychotic Disorders 2 | 151
Speech Delay 2 | 112
Speech impairment 2 | 112
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
progressive supranuclear palsy 2 | 676

Tissue

Blood and immune system 46 | 16,909
Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Female tissues 46 | 17,400
Liver and Pancreas 46 | 16,750
Male tissues 46 | 17,142
Nervous System 46 | 16,725
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Urinary Tract 46 | 16,678
Cardiovascular System 45 | 15,192

Target Family

Enzyme 27 | 4,145
Non-IDG 11 | 12,091
Kinase 5 | 634
Transcription Factor 4 | 1,400

Compartment GO Term

Endoribonuclease complex 47 | 47
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein argonaute-4 AGO4 Tbio Non-IDG -1.42077 23.0 121
tRNA-splicing endonuclease subunit Sen34 TSEN34 Tdark Enzyme -0.75841 5.30 26
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Fibrous sheath-interacting protein 1 FSIP1 Tbio Non-IDG -1.51597 37.0 113
Ribonuclease P protein subunit p40 RPP40 Tdark Enzyme -0.49995 2.84 45
Ribonuclease P protein subunit p20 POP7 Tbio Enzyme -0.86962 7.33 47
Nuclear inhibitor of protein phosphatase 1 PPP1R8 Tbio Enzyme -2.70517 500.3 281
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
Endoplasmin HSP90B1 Tchem Non-IDG -2.76074 629.2 850
Caspase-4 CASP4 Tchem Enzyme -2.19377 147.3 520