Development Level

Tbio 12 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal sleep behavior 1 | 70
abnormal spinal cord morpholog... 1 | 9
decreased B cell number 1 | 5
decreased body weight 1 | 161
decreased granulocyte number 1 | 6
decreased lean body mass 1 | 135
increased T cell number 1 | 6
increased prepulse inhibition 1 | 32
preweaning lethality, incomple... 1 | 499
vertebral fusion 1 | 23

Disease

Carcinoma 9 | 11,493
ovarian cancer 9 | 8,520
osteosarcoma 7 | 7,950
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
medulloblastoma, large-cell 5 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Astrocytoma, Pilocytic 4 | 3,081
Kidney cancer 4 | 2,613
ependymoma 4 | 4,679
Pick disease 3 | 1,894
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
non primary Sjogren syndrome sicca 3 | 891
primitive neuroectodermal tumor 3 | 3,035
psoriasis 3 | 6,694
Breast cancer 2 | 3,578
Chemical and Drug Induced Liver Injury 2 | 195
Multiple myeloma 2 | 1,332
Rheumatoid arthritis 2 | 1,191
Syringomyelia 2 | 15
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung cancer 2 | 4,740
medulloblastoma 2 | 720
oligodendroglioma 2 | 2,850
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Aggressive behavior 1 | 75
Aggressive reaction 1 | 75
Alpha 1-antitrypsin deficiency 1 | 11
Broad eyebrows 1 | 4
Broad flat nasal bridge 1 | 236
Cancer 1 | 2,499
Cardiovascular system disease 1 | 246
Cholestasis 1 | 155
Chronic obstructive pulmonary disease 1 | 184
Congenital disorder of glycosylation 1 | 54
Down syndrome 1 | 499
Downward slant of palpebral fissure 1 | 158
Duchenne muscular dystrophy 1 | 601
Epilepsy 1 | 792
Familial encephalopathy with neuroserpin inclusion bodies 1 | 10
Fundus dystrophy 1 | 83
Hyperplasia of nose 1 | 23
Hypersensitivity reaction type II disease 1 | 253
Hypertrophy of nose 1 | 23
Hypotrophic malar bone 1 | 129
Large nose 1 | 23
Liver cancer 1 | 604
Long eyebrows 1 | 2
Long narrow head 1 | 75
MENTAL RETARDATION, AUTOSOMAL RECESSIVE 15 1 | 1
Major Depressive Disorder 1 | 301
Malar flattening 1 | 129
Mediastinitis 1 | 7
Melancholia 1 | 10
Moderate mental retardation (I.Q. 35-49) 1 | 28
Myocardial Ischemia 1 | 169
Myopathy 1 | 185
Narrow cranium shape 1 | 75
Narrow head shape 1 | 75
Narrow skull shape 1 | 75
Nasal bridge wide 1 | 236
Nevoid basal cell carcinoma syndrome 1 | 16
Oculocutaneous albinism 1 | 29
Physical aggression 1 | 76
Pointed chin 1 | 33
Schizophrenia 1 | 1,160
Seizures 1 | 596
Short philtrum 1 | 53
Smooth philtrum 1 | 43
Stevens-Johnson syndrome 1 | 92
Thin upper lip vermilion 1 | 67
Turridolichocephaly 1 | 75
Unipolar Depression 1 | 250
Vascular disease 1 | 319
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
astrocytoma 1 | 1,146
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
hepatocellular carcinoma 1 | 547
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
mucosa-associated lymphoid tissue lymphoma 1 | 484
non-small cell lung carcinoma 1 | 317
progressive supranuclear palsy 1 | 676
spina bifida 1 | 1,074
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 13 | 16,909
Cardiovascular System 13 | 15,192
Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Female tissues 13 | 17,400
Liver and Pancreas 13 | 16,750
Male tissues 13 | 17,142
Nervous System 13 | 16,725
Respiratory system 13 | 16,393
Skin and soft tissues 13 | 17,230
Urinary Tract 13 | 16,678

Target Family

Enzyme 8 | 4,145
Non-IDG 5 | 12,091

Compartment GO Term

Endoplasmic reticulum quality ... 13 | 13
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 Tchem Enzyme -1.80418 63.8 91
DnaJ homolog subfamily B member 12 DNAJB12 Tbio Non-IDG -0.87804 6.09 135
ER degradation-enhancing alpha-mannosidase-like protein 3 EDEM3 Tbio Enzyme -0.60839 3.23 88
E3 ubiquitin-protein ligase synoviolin SYVN1 Tbio Enzyme -1.52336 36.2 267
Protein OS-9 OS9 Tbio Non-IDG -1.76074 57.1 170
E3 ubiquitin-protein ligase DZIP3 DZIP3 Tbio Enzyme -0.24304 1.68 116
UDP-glucose:glycoprotein glucosyltransferase 2 UGGT2 Tbio Enzyme -0.47145 1.64 93
ER degradation-enhancing alpha-mannosidase-like protein 2 EDEM2 Tbio Enzyme -0.71921 5.39 92
Calnexin CANX Tbio Non-IDG -2.87537 714.9 630
Endoplasmic reticulum lectin 1 ERLEC1 Tbio Non-IDG -2.69471 490.8 36