Development Level

Tbio 5 | 11,445
Tchem 2 | 1,598
Tdark 2 | 6,588

IMPC Phenotype

decreased circulating glucose ... 2 | 126
abnormal coat appearance 1 | 31
decreased fasted circulating g... 1 | 65
decreased urine creatinine lev... 1 | 3
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
improved glucose tolerance 1 | 79
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

osteosarcoma 6 | 7,950
ovarian cancer 6 | 8,520
glioblastoma 5 | 5,792
psoriasis 5 | 6,694
Carcinoma 4 | 11,493
adult high grade glioma 4 | 3,801
Astrocytoma, Pilocytic 3 | 3,081
Retinitis pigmentosa 26 3 | 5
atypical teratoid / rhabdoid tumor 3 | 5,112
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Breast cancer 2 | 3,578
Distal limb muscle weakness due to peripheral neuropathy 2 | 62
Distal muscle weakness 2 | 62
Distal sensory impairment 2 | 52
Distal sensory impairment of all modalities 2 | 7
Hereditary Sensory Autonomic Neuropathy, Type 1 2 | 4
Hereditary sensory neuropathy 2 | 11
Multiple myeloma 2 | 1,332
Neuropathy 2 | 261
ependymoma 2 | 4,679
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
invasive ductal carcinoma 2 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 468
Absent reflex 1 | 92
Absent tendon reflex 1 | 92
Alopecia universalis 1 | 16
Anhidrosis 1 | 23
Aortic Valve Insufficiency 1 | 40
Asthma 1 | 385
Atopic dermatitis 1 | 952
Autoamputation 1 | 2
Autoamputation of foot 1 | 2
Bipolar Disorder 1 | 666
Chronic axonal neuropathy 1 | 2
Colitis, Ulcerative 1 | 59
Congenital pes cavus 1 | 88
Decreased sensory nerve conduction velocities (NCV) 1 | 8
Decreased tendon reflex 1 | 122
Depletion of large myelinated fibers 1 | 7
Dermatologic disorders 1 | 93
Dysesthesia 1 | 6
Foot Deformities 1 | 30
Hypochondriasis 1 | 6
Infection of bone 1 | 19
Lipid storage disease 1 | 8
Loeys-Dietz syndrome 1 | 23
Lumbosacral lipoma 1 | 3
MUSCULAR DYSTROPHY, LIMB-GIRDLE, TYPE 2X 1 | 1
Multiple Sclerosis 1 | 540
Neurodegenerative disease 1 | 414
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neurotic disorder 1 | 9
Osteomyelitis 1 | 42
Osteomyelitis or necrosis, distal, due to sensory neuropathy (feet) 1 | 2
Peripheral sensorimotor neuropathy 1 | 16
Reflex, Deep Tendon, Absent 1 | 92
Sensorineural Hearing Loss (disorder) 1 | 284
Skeletal muscle atrophy 1 | 139
Skin Abnormalities 1 | 37
Skin Ulcer 1 | 48
Tabes dorsalis 1 | 6
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
colon cancer 1 | 1,478
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis 1 | 1,696
ductal carcinoma in situ 1 | 1,745
facioscapulohumeral dystrophy 1 | 288
fibroadenoma 1 | 559
group 3 medulloblastoma 1 | 4,104
hepatocellular carcinoma 1 | 547
hereditary spastic paraplegia 1 | 318
interstitial cystitis 1 | 2,312
interstitial lung disease 1 | 298
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
juvenile dermatomyositis 1 | 1,187
limb-girdle muscular dystrophy 1 | 37
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
muscle degeneration 1 | 139
non-small cell lung cancer 1 | 2,890
non-small cell lung carcinoma 1 | 317
pancreatic cancer 1 | 2,398
primary pancreatic ductal adenocarcinoma 1 | 1,109
subependymal giant cell astrocytoma 1 | 2,287
ulcerative colitis 1 | 1,819
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Enzyme 5 | 4,145
Non-IDG 4 | 12,091

Compartment GO Term

Endoplasmic reticulum palmitoy... 9 | 9
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
ORM1-like protein 2 ORMDL2 Tdark Non-IDG 0.06 0.61 64
Serine palmitoyltransferase 1 SPTLC1 Tchem Enzyme -2.16711 143.2 285
Serine palmitoyltransferase 3 SPTLC3 Tbio Enzyme -1.26166 18.5 24
Blood vessel epicardial substance BVES Tbio Non-IDG -1.50394 37.0 168
Serine palmitoyltransferase small subunit B SPTSSB Tbio Enzyme -1.56467 34.6 3
Serine palmitoyltransferase 2 SPTLC2 Tchem Enzyme -1.70805 49.3 203
Serine palmitoyltransferase small subunit A SPTSSA Tbio Enzyme -0.35857 2.20 0
ORM1-like protein 3 ORMDL3 Tbio Non-IDG -1.80514 71.8 70
ORM1-like protein 1 ORMDL1 Tdark Non-IDG -0.31066 2.48 47