Development Level

Tbio 226 | 11,445
Tchem 46 | 1,598
Tdark 19 | 6,588
Tclin 12 | 613

IMPC Phenotype

preweaning lethality, complete... 14 | 979
preweaning lethality, incomple... 11 | 499
abnormal seminal vesicle morph... 7 | 114
decreased bone mineral content 6 | 151
enlarged heart 6 | 210
increased total body fat amoun... 6 | 134
abnormal heart morphology 5 | 162
decreased circulating HDL chol... 5 | 68
decreased circulating choleste... 5 | 93
decreased total body fat amoun... 5 | 207
increased circulating alkaline... 5 | 122
increased circulating triglyce... 5 | 42
short tibia 5 | 97
abnormal embryo size 4 | 220
decreased circulating glucose ... 4 | 126
embryonic lethality prior to t... 4 | 278
impaired glucose tolerance 4 | 75
increased startle reflex 4 | 112
vertebral fusion 4 | 23
abnormal bone structure 3 | 187
abnormal femur morphology 3 | 14
decreased body length 3 | 101
decreased body weight 3 | 161
decreased circulating amylase ... 3 | 28
decreased circulating creatini... 3 | 39
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased circulating total pr... 3 | 49
decreased grip strength 3 | 116
decreased hemoglobin content 3 | 68
decreased lean body mass 3 | 135
decreased lymphocyte cell numb... 3 | 83
decreased mean corpuscular vol... 3 | 79
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
increased blood urea nitrogen ... 3 | 48
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased circulating total pr... 3 | 28
increased lean body mass 3 | 172
increased mean corpuscular hem... 3 | 36
abnormal behavior 2 | 298
abnormal coat-hair pigmentatio... 2 | 64
abnormal cranium morphology 2 | 36
abnormal eye morphology 2 | 68
abnormal humerus morphology 2 | 11
abnormal kidney morphology 2 | 65
abnormal liver morphology 2 | 17
abnormal lung morphology 2 | 26
abnormal radius morphology 2 | 8
abnormal skin morphology 2 | 50
abnormal snout morphology 2 | 23
abnormal testis morphology 2 | 43
abnormal tooth morphology 2 | 24
abnormal ulna morphology 2 | 8
decreased circulating bilirubi... 2 | 19
decreased circulating fructosa... 2 | 30
decreased circulating iron lev... 2 | 32
decreased erythrocyte cell num... 2 | 62
decreased hematocrit 2 | 46
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
decreased red blood cell distr... 2 | 41
decreased startle reflex 2 | 75
edema 2 | 59
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased bone mineral density 2 | 72
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased leukocyte cell numbe... 2 | 47
increased monocyte cell number 2 | 63
increased or absent threshold ... 2 | 101
limb grasping 2 | 41
prolonged PR interval 2 | 15
small superior vagus ganglion 2 | 74
abnormal ear morphology 1 | 9
abnormal retina morphology 1 | 71
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased circulating calcium ... 1 | 36
decreased circulating triglyce... 1 | 79
decreased heart rate variabili... 1 | 13
decreased mean corpuscular hem... 1 | 31
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased large unstained cell... 1 | 5
increased mean corpuscular vol... 1 | 92
small testis 1 | 58
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 223 | 11,493
ovarian cancer 185 | 8,520
psoriasis 145 | 6,694
glioblastoma 141 | 5,792
osteosarcoma 138 | 7,950
atypical teratoid / rhabdoid tumor 121 | 5,112
lung cancer 116 | 4,740
medulloblastoma, large-cell 112 | 6,241
ependymoma 101 | 4,679
Astrocytoma, Pilocytic 96 | 3,081
pancreatic cancer 90 | 2,398
Breast cancer 89 | 3,578
malignant mesothelioma 86 | 3,232
intraductal papillary-mucinous adenoma (IPMA) 84 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 83 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 81 | 3,291
invasive ductal carcinoma 81 | 2,951
lung adenocarcinoma 81 | 2,716
Cancer 78 | 2,499
diabetes mellitus 78 | 1,728
adult high grade glioma 74 | 3,801
non-small cell lung cancer 74 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 72 | 1,962
lung carcinoma 67 | 2,843
Autosomal recessive predisposition 65 | 1,442
Kidney cancer 64 | 2,613
cystic fibrosis 62 | 1,696
primitive neuroectodermal tumor 60 | 3,035
interstitial cystitis 59 | 2,312
ulcerative colitis 58 | 1,819
group 3 medulloblastoma 55 | 4,104
pituitary cancer 55 | 1,972
ductal carcinoma in situ 50 | 1,745
tuberculosis 50 | 2,010
breast carcinoma 49 | 1,638
juvenile dermatomyositis 49 | 1,187
oligodendroglioma 49 | 2,850
subependymal giant cell astrocytoma 48 | 2,287
adrenocortical carcinoma 47 | 1,428
primary pancreatic ductal adenocarcinoma 47 | 1,109
Duchenne muscular dystrophy 44 | 601
active Crohn's disease 43 | 922
group 4 medulloblastoma 43 | 1,855
gastric carcinoma 42 | 807
Liver Cirrhosis, Experimental 39 | 769
pediatric high grade glioma 39 | 1,064
Kidney disease 38 | 430
autosomal dominant Emery-Dreifuss muscular dystrophy 38 | 510
nasopharyngeal carcinoma 37 | 1,058
Pick disease 36 | 1,894
acute quadriplegic myopathy 35 | 1,158
esophageal adenocarcinoma 34 | 737
Atherosclerosis 33 | 291
Obesity 33 | 678
astrocytoma 33 | 1,146
Rheumatoid arthritis 32 | 1,191
astrocytic glioma 32 | 2,597
Hypertension 30 | 396
Multiple myeloma 30 | 1,332
colon cancer 29 | 1,478
Coronary artery disease 28 | 268
Liver disease 28 | 237
interstitial lung disease 28 | 298
non primary Sjogren syndrome sicca 28 | 891
Prostatic Neoplasms 27 | 495
Schizophrenia 27 | 1,160
Becker muscular dystrophy 26 | 191
Melanoma 26 | 711
Skin cancer 25 | 469
dermatomyositis 25 | 966
Atopic dermatitis 24 | 952
Hypertensive disease 24 | 292
Short stature 24 | 531
Vascular disease 24 | 319
Heart disease 23 | 306
active ulcerative colitis 23 | 764
fibroadenoma 23 | 559
Osteoporosis 22 | 363
medulloblastoma 22 | 720
Alzheimer's disease 21 | 658
limb girdle muscular dystrophy 2A 21 | 213
Arthritis 20 | 290
Liver Cirrhosis 20 | 181
Myopia 20 | 176
cutaneous lupus erythematosus 20 | 1,057
Cataract 19 | 297
Cerebrovascular disease 19 | 238
Liver cancer 19 | 604
Seizures 19 | 596
urothelial carcinoma 19 | 318
Bipolar Disorder 18 | 666
Degenerative polyarthritis 18 | 115
Down syndrome 18 | 499
Spontaneous abortion 18 | 113
Epilepsy 17 | 792
Hypoplastic mandible condyle 17 | 275
Mandibular hypoplasia 17 | 275
Micrognathism 17 | 275
Muscle hypotonia 17 | 571
aldosterone-producing adenoma 17 | 665

Tissue

Endocrine System 296 | 18,159
Female tissues 294 | 17,400
Digestive Tract 292 | 17,369
Liver and Pancreas 290 | 16,750
Male tissues 290 | 17,142
Skin and soft tissues 288 | 17,230
Urinary Tract 288 | 16,678
Blood and immune system 285 | 16,909
Nervous System 283 | 16,725
Respiratory system 276 | 16,393
Cardiovascular System 262 | 15,192

Target Family

Non-IDG 214 | 12,091
Enzyme 84 | 4,145
Transcription Factor 2 | 1,400
Ion Channel 1 | 344
Kinase 1 | 634
Transporter 1 | 473

Compartment GO Term

Endoplasmic reticulum lumen 303 | 303
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Ceroid-lipofuscinosis neuronal protein 6 CLN6 Tbio Non-IDG -1.87357 0.00000 103
Peptidyl-prolyl cis-trans isomerase FKBP7 FKBP7 Tbio Enzyme -1.41965 24.7 112
Collagen alpha-1(XXIII) chain COL23A1 Tbio Non-IDG -0.49550 1.85 112
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Arylsulfatase F ARSF Tbio Enzyme -0.44326 2.74 138
Protein Wnt-6 WNT6 Tbio Non-IDG -1.65830 46.6 186
Putative inactive carboxylesterase 4 CES1P1 Tbio Enzyme -2.62475 722.3 0
Peptidyl-prolyl cis-trans isomerase FKBP14 FKBP14 Tbio Enzyme -1.72246 54.5 157
Dipeptidyl peptidase 1 CTSC Tchem Enzyme -3.27566 1855.5 168