Development Level

Tbio 1,402 | 11,445
Tdark 270 | 6,588
Tchem 246 | 1,598
Tclin 83 | 613

Collection

Ion Channel: IDG Consortium (T... 6 | 99
Kinase: IDG Consortium (Target... 6 | 125
GPCR: IDG Consortium (Targets) 2 | 126
GPCR: IDG Consortium (Complete... 1 | 25
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 109 | 979
preweaning lethality, incomple... 68 | 499
embryonic lethality prior to t... 37 | 278
abnormal embryo size 33 | 220
embryonic lethality prior to o... 28 | 239
increased total body fat amoun... 27 | 134
decreased total body fat amoun... 26 | 207
abnormal behavior 24 | 298
increased lean body mass 23 | 172
decreased bone mineral content 22 | 151
enlarged heart 22 | 210
decreased lean body mass 21 | 135
abnormal bone structure 19 | 187
decreased body weight 19 | 161
increased startle reflex 19 | 112
hypoactivity 18 | 132
abnormal seminal vesicle morph... 17 | 114
decreased circulating choleste... 17 | 93
decreased circulating glucose ... 17 | 126
decreased vertical activity 17 | 208
decreased circulating HDL chol... 16 | 68
embryonic growth retardation 16 | 106
decreased grip strength 15 | 116
hyperactivity 15 | 148
increased circulating alkaline... 15 | 122
abnormal heart morphology 14 | 162
decreased circulating triglyce... 13 | 79
abnormal gait 12 | 69
decreased circulating serum al... 12 | 82
impaired glucose tolerance 12 | 75
increased fasted circulating g... 12 | 76
increased leukocyte cell numbe... 12 | 47
decreased bone mineral density 11 | 126
decreased lymphocyte cell numb... 11 | 83
increased bone mineral content 11 | 108
short tibia 11 | 97
decreased circulating alanine ... 10 | 47
decreased fasted circulating g... 10 | 65
decreased mean corpuscular vol... 10 | 79
increased mean corpuscular vol... 10 | 92
limb grasping 10 | 41
abnormal eye morphology 9 | 68
abnormal retina morphology 9 | 71
decreased blood urea nitrogen ... 9 | 51
decreased circulating LDL chol... 9 | 38
decreased erythrocyte cell num... 9 | 62
decreased hemoglobin content 9 | 68
decreased prepulse inhibition 9 | 82
edema 9 | 59
increased circulating triglyce... 9 | 42
increased or absent threshold ... 9 | 101
increased red blood cell distr... 9 | 34
male infertility 9 | 123
thrombocytopenia 9 | 56
abnormal kidney morphology 8 | 65
abnormal neural tube closure 8 | 46
abnormal testis morphology 8 | 43
decreased body length 8 | 101
decreased circulating alkaline... 8 | 46
decreased circulating aspartat... 8 | 34
decreased circulating insulin ... 8 | 76
decreased circulating total pr... 8 | 49
decreased startle reflex 8 | 75
increased blood urea nitrogen ... 8 | 48
increased bone mineral density 8 | 72
increased circulating amylase ... 8 | 25
increased circulating choleste... 8 | 66
increased circulating sodium l... 8 | 71
increased mean corpuscular hem... 8 | 96
abnormal lens morphology 7 | 81
abnormal locomotor behavior 7 | 24
cataract 7 | 92
decreased circulating creatini... 7 | 39
decreased circulating phosphat... 7 | 27
hydrometra 7 | 53
increased circulating HDL chol... 7 | 80
increased circulating calcium ... 7 | 34
increased grip strength 7 | 41
increased monocyte cell number 7 | 63
increased prepulse inhibition 7 | 32
small testis 7 | 58
thrombocytosis 7 | 27
tremors 7 | 39
abnormal coat-hair pigmentatio... 6 | 64
abnormal pericardium morpholog... 6 | 26
abnormal sleep behavior 6 | 70
decreased circulating amylase ... 6 | 28
decreased leukocyte cell numbe... 6 | 73
decreased mean corpuscular hem... 6 | 50
decreased red blood cell distr... 6 | 41
improved glucose tolerance 6 | 79
increased circulating chloride... 6 | 41
increased heart weight 6 | 62
increased mean platelet volume 6 | 45
increased neutrophil cell numb... 6 | 46
pallor 6 | 34
small superior vagus ganglion 6 | 74
decreased circulating fructosa... 5 | 30
pale yolk sac 5 | 25
prenatal lethality prior to he... 5 | 87

Disease

Carcinoma 1,213 | 11,493
ovarian cancer 1,045 | 8,520
osteosarcoma 872 | 7,950
psoriasis 767 | 6,694
glioblastoma 744 | 5,792
medulloblastoma, large-cell 691 | 6,241
atypical teratoid / rhabdoid tumor 607 | 5,112
lung cancer 585 | 4,740
ependymoma 535 | 4,679
intraductal papillary-mucinous neoplasm (IPMN) 448 | 3,291
Astrocytoma, Pilocytic 440 | 3,081
adult high grade glioma 437 | 3,801
Breast cancer 433 | 3,578
group 3 medulloblastoma 401 | 4,104
invasive ductal carcinoma 398 | 2,951
malignant mesothelioma 397 | 3,232
Cancer 395 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 376 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 375 | 2,955
pancreatic cancer 358 | 2,398
diabetes mellitus 354 | 1,728
lung carcinoma 353 | 2,843
non-small cell lung cancer 352 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 348 | 1,962
lung adenocarcinoma 338 | 2,716
oligodendroglioma 312 | 2,850
primitive neuroectodermal tumor 312 | 3,035
interstitial cystitis 288 | 2,312
tuberculosis 286 | 2,010
subependymal giant cell astrocytoma 280 | 2,287
astrocytic glioma 263 | 2,597
pituitary cancer 258 | 1,972
Kidney cancer 257 | 2,613
Autosomal recessive predisposition 255 | 1,442
ulcerative colitis 252 | 1,819
cystic fibrosis 245 | 1,696
Pick disease 241 | 1,894
breast carcinoma 232 | 1,638
Multiple myeloma 231 | 1,332
group 4 medulloblastoma 229 | 1,855
ductal carcinoma in situ 228 | 1,745
Rheumatoid arthritis 188 | 1,191
adrenocortical carcinoma 186 | 1,428
active Crohn's disease 178 | 922
astrocytoma 175 | 1,146
juvenile dermatomyositis 175 | 1,187
acute quadriplegic myopathy 170 | 1,158
colon cancer 170 | 1,478
Schizophrenia 161 | 1,160
primary pancreatic ductal adenocarcinoma 161 | 1,109
dermatomyositis 155 | 966
pediatric high grade glioma 154 | 1,064
Liver Cirrhosis, Experimental 136 | 769
Epilepsy 132 | 792
esophageal adenocarcinoma 132 | 737
Obesity 130 | 678
Alzheimer's disease 128 | 658
Intellectual disability 127 | 1,016
cutaneous lupus erythematosus 123 | 1,057
non primary Sjogren syndrome sicca 119 | 891
gastric carcinoma 118 | 807
nasopharyngeal carcinoma 115 | 1,058
Duchenne muscular dystrophy 113 | 601
Atopic dermatitis 112 | 952
Kidney disease 111 | 430
active ulcerative colitis 111 | 764
Arthritis 110 | 290
Hypertension 108 | 396
spina bifida 106 | 1,074
Prostatic Neoplasms 105 | 495
Seizures 104 | 596
Neurodegenerative disease 103 | 414
Anemia 93 | 365
Bipolar Disorder 93 | 666
autosomal dominant Emery-Dreifuss muscular dystrophy 93 | 510
Hypersensitivity reaction type II disease 92 | 253
Melanoma 91 | 711
Waldenstrons macroglobulinemia 91 | 765
Liver disease 90 | 237
acute myeloid leukemia 90 | 783
pancreatic carcinoma 90 | 562
Heart disease 89 | 306
Down syndrome 88 | 499
Muscle hypotonia 88 | 571
progressive supranuclear palsy 88 | 676
aldosterone-producing adenoma 87 | 665
primary Sjogren syndrome 87 | 735
Ankylosing spondylitis 86 | 140
Atherosclerosis 85 | 291
Multiple Sclerosis 84 | 540
Dull intelligence 81 | 645
Low intelligence 81 | 645
Mental Retardation 81 | 645
Mental deficiency 81 | 645
Poor school performance 81 | 645
fibroadenoma 79 | 559
Cognitive delay 78 | 608
Global developmental delay 78 | 608
Mental and motor retardation 78 | 608
Vascular disease 78 | 319

Tissue

Endocrine System 1,859 | 18,159
Digestive Tract 1,848 | 17,369
Female tissues 1,843 | 17,400
Skin and soft tissues 1,834 | 17,230
Liver and Pancreas 1,824 | 16,750
Male tissues 1,822 | 17,142
Blood and immune system 1,806 | 16,909
Urinary Tract 1,805 | 16,678
Nervous System 1,794 | 16,725
Respiratory system 1,773 | 16,393
Cardiovascular System 1,681 | 15,192

Target Family

Non-IDG 1,152 | 12,091
Enzyme 655 | 4,145
Transporter 53 | 473
Kinase 50 | 634
Ion Channel 43 | 344
Transcription Factor 32 | 1,400
GPCR 14 | 408
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Endoplasmic reticulum 2,001 | 2,001
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Trafficking protein particle complex subunit 2-like protein TRAPPC2L Tdark Non-IDG -0.18066 0.74 35
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
Peroxisomal membrane protein PEX16 PEX16 Tbio Non-IDG -1.43594 27.8 78
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
UbiA prenyltransferase domain-containing protein 1 UBIAD1 Tbio Enzyme -1.59893 42.5 50
Probable ergosterol biosynthetic protein 28 ERG28 Tdark Non-IDG -1.25331 16.7 40
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
Tyrosine-protein phosphatase non-receptor type 5 PTPN5 Tchem Enzyme -1.85420 70.8 225
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514