Development Level

Tbio 57 | 11,445
Tchem 10 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 6 | 979
preweaning lethality, incomple... 4 | 499
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
decreased circulating insulin ... 2 | 76
decreased red blood cell distr... 2 | 41
increased bone mineral density 2 | 72
increased grip strength 2 | 41
increased lean body mass 2 | 172
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal hindbrain development 1 | 16
abnormal kidney morphology 1 | 65
abnormal neural tube closure 1 | 46
abnormal placement of pupils 1 | 6
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
absent spleen 1 | 3
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased IgG1 level 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased spleen weight 1 | 10
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hyperactivity 1 | 148
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating total pr... 1 | 28
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 46 | 11,493
osteosarcoma 41 | 7,950
ovarian cancer 35 | 8,520
lung cancer 32 | 4,740
Cancer 30 | 2,499
psoriasis 26 | 6,694
medulloblastoma, large-cell 23 | 6,241
group 3 medulloblastoma 22 | 4,104
glioblastoma 21 | 5,792
atypical teratoid / rhabdoid tumor 17 | 5,112
malignant mesothelioma 17 | 3,232
Breast cancer 16 | 3,578
diabetes mellitus 13 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,291
Kidney cancer 12 | 2,613
lung adenocarcinoma 11 | 2,716
non-small cell lung cancer 11 | 2,890
Multiple myeloma 10 | 1,332
ependymoma 10 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Autosomal recessive predisposition 9 | 1,442
Bloom syndrome 9 | 29
Intellectual disability 9 | 1,016
Neurodegenerative disease 9 | 414
Pick disease 9 | 1,894
Schizophrenia 9 | 1,160
pancreatic cancer 9 | 2,398
primitive neuroectodermal tumor 9 | 3,035
tuberculosis 9 | 2,010
Alzheimer's disease 8 | 658
adult high grade glioma 8 | 3,801
astrocytic glioma 8 | 2,597
invasive ductal carcinoma 8 | 2,951
oligodendroglioma 8 | 2,850
Fanconi anemia 7 | 56
Vascular disease 7 | 319
Xeroderma pigmentosum 7 | 43
Xeroderma pigmentosum group F 7 | 22
Xeroderma pigmentosum group G 7 | 16
acute myeloid leukemia 7 | 783
cystic fibrosis 7 | 1,696
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Cockayne syndrome 6 | 60
Depressive disorder 6 | 409
Epilepsy 6 | 792
Melanoma 6 | 711
Obesity 6 | 678
Prostatic Neoplasms 6 | 495
Rheumatoid arthritis 6 | 1,191
Small head 6 | 374
Stomach Neoplasms 6 | 300
Toxic encephalopathy 6 | 141
astrocytoma 6 | 1,146
colon cancer 6 | 1,478
hepatocellular carcinoma 6 | 547
lung carcinoma 6 | 2,843
non primary Sjogren syndrome sicca 6 | 891
pancreatic carcinoma 6 | 562
Basal cell carcinoma 5 | 54
Cognitive delay 5 | 608
Colorectal Neoplasms 5 | 243
Dull intelligence 5 | 645
Genetic Predisposition to Disease 5 | 27
Global developmental delay 5 | 608
Heart disease 5 | 306
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Micronuclei, Chromosome-Defective 5 | 25
Muscle hypotonia 5 | 571
Parkinson's disease 5 | 392
Poor school performance 5 | 645
Seizures 5 | 596
Waldenstrons macroglobulinemia 5 | 765
breast carcinoma 5 | 1,638
group 4 medulloblastoma 5 | 1,855
medulloblastoma 5 | 720
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Adenocarcinoma of lung 4 | 142
Bipolar Disorder 4 | 666
Fatigue 4 | 182
Hyperreflexia 4 | 209
Keratitis 4 | 62
Kidney disease 4 | 430
Mental Depression 4 | 333
Movement Disorders 4 | 55
Muscle Spasticity 4 | 195
Myocardial Infarction 4 | 151
Pontocerebellar hypoplasia 4 | 36
Sensorineural Hearing Loss (disorder) 4 | 284
Short stature 4 | 531
Xeroderma pigmentosum group D 4 | 33
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
spina bifida 4 | 1,074

Tissue

Blood and immune system 70 | 16,909
Digestive Tract 70 | 17,369
Endocrine System 70 | 18,159
Female tissues 70 | 17,400
Liver and Pancreas 70 | 16,750
Male tissues 70 | 17,142
Nervous System 70 | 16,725
Respiratory system 70 | 16,393
Skin and soft tissues 70 | 17,230
Urinary Tract 70 | 16,678
Cardiovascular System 68 | 15,192

Target Family

Enzyme 41 | 4,145
Non-IDG 21 | 12,091
Kinase 5 | 634
Transcription Factor 4 | 1,400

Compartment GO Term

Endonuclease complex 71 | 71
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
X-box-binding protein 1 XBP1 Tchem Transcription Factor -2.90444 780.2 514
Protein HEG homolog 1 HEG1 Tbio Non-IDG -2.11308 129.3 11
Peroxidasin-like protein PXDNL Tbio Non-IDG -1.10753 14.4 0
Cleavage and polyadenylation specificity factor subunit 3 CPSF3 Tbio Non-IDG -1.47182 27.3 190
Protein argonaute-4 AGO4 Tbio Non-IDG -1.42077 23.0 121
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.52158 32564.4 32
Uracil-DNA glycosylase UNG Tbio Enzyme -2.82957 680.9 352
tRNA-splicing endonuclease subunit Sen34 TSEN34 Tdark Enzyme -0.75841 5.30 26
ATP-dependent RNA helicase A DHX9 Tbio Enzyme -2.85807 734.3 204
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.26147 1834.9 293