Development Level

Tchem 6 | 1,598

IMPC Phenotype

short tibia 2 | 97
abnormal clavicle morphology 1 | 6
decreased heart weight 1 | 27
decreased prepulse inhibition 1 | 82
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
small superior vagus ganglion 1 | 74

Disease

glioblastoma 6 | 5,792
Cancer 5 | 2,499
ovarian cancer 5 | 8,520
Carcinoma 4 | 11,493
Chronic hepatitis C 4 | 12
cutaneous lupus erythematosus 4 | 1,057
diabetes mellitus 4 | 1,728
Arthritis 3 | 290
Duchenne muscular dystrophy 3 | 601
acute quadriplegic myopathy 3 | 1,158
cystic fibrosis 3 | 1,696
gastric carcinoma 3 | 807
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Fascioliasis 2 | 17
Liver Cirrhosis, Experimental 2 | 769
Neoplasm Invasiveness 2 | 161
Obesity 2 | 678
Osteoporosis 2 | 363
Proteinuria 2 | 144
Pycnodysostosis 2 | 5
Schistosomiasis 2 | 35
Sleeping sickness 2 | 37
Vascular disease 2 | 319
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
group 3 medulloblastoma 2 | 4,104
invasive ductal carcinoma 2 | 2,951
lung cancer 2 | 4,740
medulloblastoma, large-cell 2 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
periodontitis 2 | 293
primary Sjogren syndrome 2 | 735
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
ulcerative colitis 2 | 1,819
Abnormal skeletal development 1 | 60
Abnormality of epiphysis morphology 1 | 39
Abnormality of pelvic girdle bone morphology 1 | 37
Barrett's esophagus 1 | 182
Blue sclera 1 | 32
Bone pain 1 | 42
Brachycephaly 1 | 88
Brachydactyly 1 | 156
Broad cranium shape 1 | 88
Carcinoma, Renal Cell 1 | 124
Chagas disease 1 | 39
Dental abnormalities 1 | 60
Dental caries 1 | 164
Exophthalmos 1 | 112
Failure of exfoliation of primary tooth 1 | 8
Frequent fractures 1 | 53
Frontal bossing 1 | 157
Generalized anxiety disorder 1 | 29
High forehead 1 | 102
Hyperplasia of nose 1 | 23
Hypertrophy of nose 1 | 23
Hypodontia 1 | 81
Hypoplastic toes 1 | 29
Hypotrophic malar bone 1 | 129
Increased fracture rate 1 | 53
Large nose 1 | 23
Late tooth eruption 1 | 61
Lytic lesion 1 | 32
Malar flattening 1 | 129
Muscular Diseases 1 | 27
Necrosis 1 | 53
Osteochondrodysplasias 1 | 72
Osteonecrosis 1 | 27
Osteopetrosis 1 | 43
Panic disorder 1 | 61
Prominent back of the head 1 | 21
Prominent eyes 1 | 96
Prominent globes 1 | 96
Prominent occiput 1 | 21
Protruding eyes 1 | 96
Renal Cell Carcinoma 1 | 214
Ridged nails 1 | 14
Root resorption 1 | 22
Severe acute respiratory syndrome 1 | 27
Structure of wormian bone 1 | 24
Tall forehead 1 | 102
Tooth Abnormalities 1 | 69
Trichomoniasis 1 | 10
Varying degree of multiple fractures 1 | 53
Wide skull shape 1 | 88
inflammatory breast cancer 1 | 286
obsessive-compulsive disorder 1 | 61
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678

Target Family

Enzyme 5 | 4,145
Ion Channel 1 | 344

Compartment GO Term

Endolysosome lumen 6 | 6
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cathepsin S CTSS Tchem Enzyme -3.31099 1955.9 291
Cathepsin B CTSB Tchem Enzyme -3.72723 5011.5 448
Cathepsin K CTSK Tchem Enzyme -2.98138 936.0 404
Cathepsin L1 CTSL Tchem Enzyme -3.39489 2387.3 416
P2X purinoceptor 4 P2RX4 Tchem Ion Channel -2.49038 314.8 181
Legumain LGMN Tchem Enzyme -2.36019 233.2 207