Development Level

Tbio 173 | 10,625
Tchem 30 | 1,890
Tdark 8 | 7,003
Tclin 5 | 602

Collection

Eligible Ion Channel Proteins 3 | 117

IMPC Term

preweaning lethality, complete... 10 | 633
decreased grip strength 5 | 123
embryonic lethality prior to t... 5 | 187
abnormal behavior 4 | 226
cardiovascular system phenotyp... 4 | 35
decreased total body fat amoun... 4 | 186
abnormal lens morphology 3 | 73
abnormal limb bud morphology 3 | 15
abnormal sleep behavior 3 | 63
decreased bone mineral content 3 | 157
decreased lean body mass 3 | 195
decreased mean corpuscular vol... 3 | 50
short tibia 3 | 82
abnormal QRS complex 2 | 25
abnormal body wall morphology 2 | 7
abnormal bone structure 2 | 131
abnormal craniofacial morpholo... 2 | 12
abnormal embryo size 2 | 112
abnormal facial morphology 2 | 9
abnormal limb morphology 2 | 7
abnormal pericardium morpholog... 2 | 11
anophthalmia 2 | 20
cleft palate 2 | 6
decreased body length 2 | 108
decreased body weight 2 | 174
decreased bone mineral density 2 | 126
decreased circulating triglyce... 2 | 83
decreased lumbar vertebrae num... 2 | 62
edema 2 | 11
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
facial cleft 2 | 3
hydrops fetalis 2 | 22
hypoactivity 2 | 89
increased bone mineral content 2 | 92
increased circulating chloride... 2 | 43
increased circulating choleste... 2 | 53
polydactyly 2 | 22
preweaning lethality, incomple... 2 | 260
abnormal digit morphology 1 | 13
abnormal embryo development 1 | 2
abnormal embryo turning 1 | 15
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal kidney morphology 1 | 30
abnormal posture 1 | 5
abnormal retinal blood vessel ... 1 | 18
abnormal seminal vesicle morph... 1 | 47
absent pinna reflex 1 | 21
cataract 1 | 26
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased cardiac muscle contr... 1 | 5
decreased caudal vertebrae num... 1 | 49
decreased circulating HDL chol... 1 | 77
decreased circulating amylase ... 1 | 24
decreased circulating aspartat... 1 | 27
decreased circulating choleste... 1 | 85
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased effector memory CD8-... 1 | 24
decreased exploration in new e... 1 | 9
decreased heart rate 1 | 10
decreased heart rate variabili... 1 | 11
decreased mean corpuscular hem... 1 | 19
decreased neutrophil cell numb... 1 | 37
decreased prepulse inhibition 1 | 52
decreased vertical activity 1 | 22
enlarged spleen 1 | 26
hydrometra 1 | 13
hyperactivity 1 | 108
impaired righting response 1 | 19
increased body weight 1 | 42
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased circulating phosphat... 1 | 24
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased grip strength 1 | 83
increased heart rate variabili... 1 | 4
increased hematocrit 1 | 36
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased sacral vertebrae num... 1 | 62
increased spleen weight 1 | 3
increased startle reflex 1 | 38
microphthalmia 1 | 15
pallor 1 | 13
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
stereotypic behavior 1 | 3
tremors 1 | 34
trunk curl 1 | 15

Disease

psoriasis 120 | 6,685
Cancer 103 | 2,346
diabetes mellitus 84 | 1,663
ovarian cancer 81 | 8,492
Ankylosing spondylitis 71 | 138
osteosarcoma 66 | 7,933
Hypersensitivity reaction type II disease 65 | 235
glioblastoma 65 | 5,572
Juvenile rheumatoid arthritis 61 | 105
Arthritis 60 | 248
lung carcinoma 59 | 2,844
Acquired immunodeficiency syndrome 57 | 164
Uveitis 57 | 103
Behcet's disease 56 | 74
medulloblastoma, large-cell 56 | 6,234
Rheumatoid Arthritis 55 | 1,171
Human immunodeficiency virus infectious disease 53 | 129
Psoriatic arthritis 52 | 85
Stevens-Johnson syndrome 51 | 91
lung cancer 51 | 4,473
dermatomyositis 48 | 967
pilocytic astrocytoma 46 | 3,086
atypical teratoid / rhabdoid tumor 43 | 4,369
Dermatitis 37 | 141
Synovitis 36 | 72
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 74
Nephritis 35 | 63
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 54
drug-induced hepatitis 35 | 44
invasive ductal carcinoma 35 | 2,950
pediatric high grade glioma 34 | 2,712
subependymal giant cell astrocytoma 34 | 2,287
Multiple Sclerosis 32 | 498
Kidney disease 30 | 397
interstitial cystitis 30 | 2,299
malignant mesothelioma 29 | 3,163
non-small cell lung cancer 29 | 2,798
primitive neuroectodermal tumor 29 | 3,031
Leprosy 28 | 77
Liver disease 28 | 219
astrocytoma 28 | 1,493
posterior fossa group A ependymoma 28 | 1,511
Breast cancer 27 | 3,099
ulcerative colitis 27 | 2,087
pancreatic cancer 26 | 2,300
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,956
lung adenocarcinoma 25 | 2,714
Anemia 24 | 252
oligodendroglioma 24 | 2,849
Hemochromatosis 23 | 55
Hepatitis B 23 | 103
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
ependymoma 22 | 2,514
Birdshot chorioretinopathy 21 | 23
Primary immunodeficiency disease 21 | 52
Skin disease 21 | 65
breast carcinoma 21 | 1,614
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,289
juvenile dermatomyositis 21 | 1,189
tuberculosis 21 | 1,563
cutaneous lupus erythematosus 20 | 1,056
Carcinoma 18 | 2,147
Pick disease 18 | 1,893
cystic fibrosis 18 | 1,670
pituitary cancer 18 | 1,972
astrocytic glioma 17 | 2,241
ductal carcinoma in situ 17 | 1,745
primary pancreatic ductal adenocarcinoma 17 | 1,271
Multiple myeloma 16 | 1,328
adrenocortical carcinoma 16 | 1,427
adult high grade glioma 16 | 2,148
group 3 medulloblastoma 16 | 2,254
medulloblastoma 16 | 1,524
pre-eclampsia 16 | 67
group 4 medulloblastoma 15 | 1,875
primary Sjogren syndrome 15 | 789
Human immunodeficiency virus type 1, susceptibility to 14 | 26
Psoriasis susceptibility 1 14 | 14
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,795
Duchenne muscular dystrophy 13 | 602
colon cancer 13 | 1,475
Alzheimer's disease 12 | 644
esophageal adenocarcinoma 12 | 737
gastric carcinoma 12 | 832
Atherosclerosis 11 | 275
active Crohn's disease 11 | 918
mucosa-associated lymphoid tissue lymphoma 11 | 480
posterior fossa group B ependymoma 11 | 1,530
sonic hedgehog group medulloblastoma 11 | 1,482
Prostatic Neoplasms 10 | 471
Schizophrenia 10 | 503
spina bifida 10 | 1,064
fibroadenoma 9 | 557
IGA Glomerulonephritis 8 | 454
sarcoidosis 8 | 368
Becker muscular dystrophy 7 | 187
Intellectual disability 7 | 573

Tissue

Digestive Tract 153 | 18,473
Endocrine System 153 | 18,512
Female tissues 153 | 18,647
Liver and Pancreas 153 | 18,136
Nervous System 153 | 18,561
Urinary Tract 153 | 18,444
Cardiovascular System 152 | 17,958
Blood and immune system 151 | 17,995
Male tissues 151 | 17,969
Respiratory system 151 | 17,484
Skin and soft tissues 145 | 18,115

Target Family

Non-IDG 156 | 11,969
Enzyme 37 | 4,146
Ion Channel 9 | 341
Kinase 7 | 634
GPCR 5 | 408
Transporter 2 | 473

Compartment GO Term

Endocytic vesicle membrane 216 | 216
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.43448 279.3 62
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.07995 1275.9 729
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.86758 701.8 663
Smoothened homolog SMO Tclin GPCR -1.11229 12.5 388
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tchem Enzyme -2.93891 844.0 215
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274
V-type proton ATPase 116 kDa subunit a isoform 3 TCIRG1 Tbio Enzyme -1.88588 86.2 59
HLA class I histocompatibility antigen, A-3 alpha chain HLA-A Tbio Non-IDG -2.40709 4042.7 585
Ras-related C3 botulinum toxin substrate 2 RAC2 Tchem Enzyme -2.87547 633.7 216
Frizzled-5 FZD5 Tbio GPCR -1.49711 28.9 256