Development Level

Tbio 236 | 10,625
Tchem 49 | 1,890
Tclin 12 | 602
Tdark 11 | 7,003

Collection

Eligible Ion Channel Proteins 3 | 117

IMPC Term

preweaning lethality, complete... 16 | 633
decreased grip strength 7 | 123
increased circulating alkaline... 7 | 119
decreased total body fat amoun... 5 | 186
embryonic lethality prior to t... 5 | 187
short tibia 5 | 82
abnormal behavior 4 | 226
abnormal bone structure 4 | 131
abnormal lens morphology 4 | 73
cardiovascular system phenotyp... 4 | 35
decreased bone mineral content 4 | 157
decreased lean body mass 4 | 195
decreased mean corpuscular vol... 4 | 50
abnormal embryo size 3 | 112
abnormal eye morphology 3 | 38
abnormal limb bud morphology 3 | 15
abnormal sleep behavior 3 | 63
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 77
decreased circulating choleste... 3 | 85
increased circulating HDL chol... 3 | 63
increased circulating choleste... 3 | 53
increased grip strength 3 | 83
increased lean body mass 3 | 107
preweaning lethality, incomple... 3 | 260
tremors 3 | 34
abnormal QRS complex 2 | 25
abnormal body wall morphology 2 | 7
abnormal craniofacial morpholo... 2 | 12
abnormal facial morphology 2 | 9
abnormal heart left ventricle ... 2 | 20
abnormal limb morphology 2 | 7
abnormal locomotor activation 2 | 26
abnormal pericardium morpholog... 2 | 11
abnormal posture 2 | 5
abnormal retina morphology 2 | 100
abnormal tooth morphology 2 | 24
anophthalmia 2 | 20
cataract 2 | 26
cleft palate 2 | 6
decreased caudal vertebrae num... 2 | 49
decreased circulating alkaline... 2 | 41
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased effector memory CD8-... 2 | 24
decreased fasted circulating g... 2 | 49
decreased heart weight 2 | 44
decreased lumbar vertebrae num... 2 | 62
decreased mean corpuscular hem... 2 | 19
decreased pulmonary respirator... 2 | 4
edema 2 | 11
embryonic lethality prior to o... 2 | 148
enlarged heart 2 | 111
enlarged stomach 2 | 2
facial cleft 2 | 3
hydrops fetalis 2 | 22
hypoactivity 2 | 89
impaired glucose tolerance 2 | 52
increased bone mineral content 2 | 92
increased circulating LDL chol... 2 | 15
increased circulating chloride... 2 | 43
increased circulating free fat... 2 | 17
increased circulating phosphat... 2 | 24
increased circulating potassiu... 2 | 31
increased hematocrit 2 | 36
lethargy 2 | 5
polydactyly 2 | 22
small thymus 2 | 11
abnormal coat appearance 1 | 25
abnormal embryo turning 1 | 15
abnormal kidney morphology 1 | 30
abnormal retinal pigmentation 1 | 61
absent pinna reflex 1 | 21
decreased NK cell number 1 | 16
decreased blood urea nitrogen ... 1 | 31
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating sodium l... 1 | 18
decreased exploration in new e... 1 | 9
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
enlarged spleen 1 | 26
impaired righting response 1 | 19
increased body weight 1 | 42
increased circulating bilirubi... 1 | 16
increased circulating fructosa... 1 | 11
increased circulating triglyce... 1 | 24
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 91
increased sacral vertebrae num... 1 | 62
persistence of hyaloid vascula... 1 | 22
prenatal lethality 1 | 16
prenatal lethality prior to he... 1 | 64
stereotypic behavior 1 | 3
straub tail 1 | 26
thrombocytopenia 1 | 46
trunk curl 1 | 15

Disease

psoriasis 165 | 6,685
Cancer 137 | 2,346
ovarian cancer 133 | 8,492
osteosarcoma 113 | 7,933
diabetes mellitus 104 | 1,663
glioblastoma 100 | 5,572
medulloblastoma, large-cell 92 | 6,234
lung carcinoma 83 | 2,844
lung cancer 82 | 4,473
Rheumatoid Arthritis 76 | 1,171
Ankylosing spondylitis 72 | 138
Hypersensitivity reaction type II disease 70 | 235
Arthritis 69 | 248
pilocytic astrocytoma 64 | 3,086
Juvenile rheumatoid arthritis 63 | 105
Uveitis 60 | 103
atypical teratoid / rhabdoid tumor 60 | 4,369
invasive ductal carcinoma 60 | 2,950
non-small cell lung cancer 59 | 2,798
Acquired immunodeficiency syndrome 58 | 164
Human immunodeficiency virus infectious disease 57 | 129
dermatomyositis 57 | 967
Behcet's disease 56 | 74
Psoriatic arthritis 53 | 85
malignant mesothelioma 52 | 3,163
Stevens-Johnson syndrome 51 | 91
lung adenocarcinoma 50 | 2,714
pediatric high grade glioma 49 | 2,712
pancreatic cancer 47 | 2,300
interstitial cystitis 46 | 2,299
subependymal giant cell astrocytoma 46 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,956
tuberculosis 45 | 1,563
Kidney disease 44 | 397
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,988
ulcerative colitis 42 | 2,087
Breast cancer 41 | 3,099
Dermatitis 40 | 141
oligodendroglioma 40 | 2,849
Liver disease 38 | 219
Multiple Sclerosis 38 | 498
astrocytoma 38 | 1,493
primitive neuroectodermal tumor 38 | 3,031
Carcinoma 37 | 2,147
Nephritis 37 | 63
Synovitis 37 | 72
intraductal papillary-mucinous neoplasm (IPMN) 37 | 3,289
juvenile dermatomyositis 37 | 1,189
Anemia 36 | 252
Behcet's syndrome 36 | 50
Retinal vasculitis 36 | 36
Takayasu's arteritis 36 | 54
Congenital adrenal hyperplasia 35 | 74
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
posterior fossa group A ependymoma 35 | 1,511
breast carcinoma 34 | 1,614
ependymoma 33 | 2,514
cutaneous lupus erythematosus 32 | 1,056
Hepatitis B 30 | 103
Hemochromatosis 29 | 55
Leprosy 29 | 77
Multiple myeloma 29 | 1,328
Pick disease 29 | 1,893
adult high grade glioma 27 | 2,148
cystic fibrosis 27 | 1,670
colon cancer 26 | 1,475
pituitary cancer 26 | 1,972
primary pancreatic ductal adenocarcinoma 26 | 1,271
astrocytic glioma 25 | 2,241
ductal carcinoma in situ 25 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,795
acute quadriplegic myopathy 24 | 1,157
group 4 medulloblastoma 24 | 1,875
primary Sjogren syndrome 24 | 789
Alzheimer's disease 22 | 644
Primary immunodeficiency disease 22 | 52
adrenocortical carcinoma 22 | 1,427
group 3 medulloblastoma 22 | 2,254
mucosa-associated lymphoid tissue lymphoma 22 | 480
Birdshot chorioretinopathy 21 | 23
Skin disease 21 | 65
esophageal adenocarcinoma 21 | 737
medulloblastoma 21 | 1,524
Atherosclerosis 20 | 275
Duchenne muscular dystrophy 20 | 602
gastric carcinoma 20 | 832
Schizophrenia 18 | 503
Asthma 16 | 349
Atopic dermatitis 16 | 944
acute myeloid leukemia 16 | 785
nasopharyngeal carcinoma 16 | 1,056
pancreatic carcinoma 16 | 567
pre-eclampsia 16 | 67
sonic hedgehog group medulloblastoma 16 | 1,482
spina bifida 16 | 1,064
Vascular disease 15 | 281
posterior fossa group B ependymoma 15 | 1,530
Intellectual disability 14 | 573
Obesity 14 | 616

Tissue

Liver and Pancreas 242 | 18,136
Nervous System 242 | 18,561
Digestive Tract 241 | 18,473
Female tissues 241 | 18,647
Urinary Tract 241 | 18,444
Endocrine System 240 | 18,512
Blood and immune system 239 | 17,995
Cardiovascular System 239 | 17,958
Male tissues 239 | 17,969
Respiratory system 237 | 17,484
Skin and soft tissues 231 | 18,115

Target Family

Non-IDG 222 | 11,969
Enzyme 56 | 4,146
Ion Channel 10 | 341
Kinase 8 | 634
Transporter 6 | 473
GPCR 5 | 408
Transcription Factor 1 | 1,400

Compartment GO Term

Endocytic vesicle 308 | 308
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
V-type proton ATPase 116 kDa subunit a isoform 2 ATP6V0A2 Tbio Enzyme -2.43448 279.3 62
HLA class I histocompatibility antigen, alpha chain G HLA-G Tbio Non-IDG -3.07995 1275.9 729
Scavenger receptor cysteine-rich type 1 protein M130 CD163 Tbio Non-IDG -2.86758 701.8 663
Smoothened homolog SMO Tclin GPCR -1.11229 12.5 388
Rap guanine nucleotide exchange factor 2 RAPGEF2 Tbio Non-IDG -1.34433 25.0 58
Secretoglobin family 3A member 2 SCGB3A2 Tbio Non-IDG -1.38373 28.8 22
Hypoxia up-regulated protein 1 HYOU1 Tbio Non-IDG -1.98190 108.3 168
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tchem Enzyme -2.93891 844.0 215
HLA class II histocompatibility antigen, DP beta 1 chain HLA-DPB1 Tbio Non-IDG -2.67719 572.7 274
V-type proton ATPase 116 kDa subunit a isoform 3 TCIRG1 Tbio Enzyme -1.88588 86.2 59