Development Level

Tbio 266 | 10,625
Tchem 48 | 1,890
Tdark 35 | 7,003
Tclin 13 | 602

Collection

Kinase: IDG Consortium (Complete/Control) 1 | 37
Kinase: IDG Consortium (Targets) 1 | 125

IMPC Phenotype

preweaning lethality, complete... 12 | 633
decreased grip strength 7 | 123
increased circulating HDL chol... 5 | 63
preweaning lethality, incomple... 5 | 260
decreased mean corpuscular hem... 4 | 34
increased circulating alkaline... 4 | 119
increased circulating choleste... 4 | 53
abnormal retinal pigmentation 3 | 61
decreased NK T cell number 3 | 28
decreased body length 3 | 108
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 77
decreased circulating LDL chol... 3 | 37
decreased lean body mass 3 | 195
decreased lumbar vertebrae num... 3 | 62
decreased mean corpuscular vol... 3 | 50
decreased total body fat amoun... 3 | 186
hypoactivity 3 | 89
increased circulating LDL chol... 3 | 15
increased fasted circulating g... 3 | 68
increased sacral vertebrae num... 3 | 62
abnormal kidney morphology 2 | 30
abnormal retina morphology 2 | 100
abnormal seminal vesicle morph... 2 | 47
abnormal sleep behavior 2 | 63
abnormal thoracic cage shape 2 | 3
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased circulating serum al... 2 | 79
decreased circulating triglyce... 2 | 83
decreased leukocyte cell numbe... 2 | 54
decreased mean corpuscular hem... 2 | 19
decreased monocyte cell number 2 | 28
decreased prepulse inhibition 2 | 52
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
enlarged heart 2 | 111
improved glucose tolerance 2 | 56
increased B cell number 2 | 23
increased T cell number 2 | 15
increased bone mineral density 2 | 52
increased circulating chloride... 2 | 43
increased circulating serum al... 2 | 25
increased leukocyte cell numbe... 2 | 37
increased mean corpuscular hem... 2 | 93
increased mean corpuscular vol... 2 | 91
short tibia 2 | 82
abnormal QRS complex 1 | 25
abnormal body wall morphology 1 | 7
abnormal coping response 1 | 12
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal gait 1 | 51
abnormal lens morphology 1 | 73
abnormal motor capabilities-co... 1 | 4
abnormal respiratory quotient 1 | 9
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 14
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C high monocyte n... 1 | 18
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased blood urea nitrogen ... 1 | 31
decreased circulating chloride... 1 | 32
decreased circulating potassiu... 1 | 17
decreased circulating sodium l... 1 | 18
decreased effector memory CD8-... 1 | 24
decreased eosinophil cell numb... 1 | 41
decreased follicular B cell nu... 1 | 4
decreased neutrophil cell numb... 1 | 37
decreased rib number 1 | 59
decreased threshold for audito... 1 | 32
decreased total retina thickne... 1 | 20
enlarged spleen 1 | 26
hydrometra 1 | 13
increased NK T cell number 1 | 11
increased body weight 1 | 42
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 32
increased circulating fructosa... 1 | 11
increased circulating iron lev... 1 | 25
increased circulating potassiu... 1 | 31
increased circulating total pr... 1 | 20
increased circulating triglyce... 1 | 24
increased eosinophil cell numb... 1 | 9
increased erythrocyte cell num... 1 | 26
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
oligodactyly 1 | 14
premature death 1 | 5
shortened ST segment 1 | 9
straub tail 1 | 26
thrombocytosis 1 | 23

Disease

ovarian cancer 181 | 8,491
psoriasis 176 | 6,685
osteosarcoma 145 | 7,933
Cancer 129 | 2,346
medulloblastoma, large-cell 117 | 6,234
glioblastoma 113 | 5,572
diabetes mellitus 99 | 1,663
lung cancer 82 | 4,473
Ankylosing spondylitis 72 | 138
atypical teratoid / rhabdoid tumor 71 | 4,369
Arthritis 66 | 248
invasive ductal carcinoma 65 | 2,950
Hypersensitivity reaction type II disease 62 | 235
Rheumatoid Arthritis 61 | 1,170
dermatomyositis 61 | 966
pilocytic astrocytoma 61 | 3,086
Acquired immunodeficiency syndrome 58 | 164
Behcet's disease 57 | 74
Uveitis 57 | 103
Juvenile rheumatoid arthritis 56 | 105
malignant mesothelioma 56 | 3,163
Human immunodeficiency virus infectious disease 55 | 129
intraductal papillary-mucinous neoplasm (IPMN) 55 | 3,289
pediatric high grade glioma 55 | 2,712
subependymal giant cell astrocytoma 55 | 2,287
Stevens-Johnson syndrome 53 | 91
intraductal papillary-mucinous adenoma (IPMA) 53 | 2,956
Breast cancer 52 | 3,098
lung adenocarcinoma 52 | 2,714
non-small cell lung cancer 51 | 2,798
Psoriatic arthritis 49 | 85
lung carcinoma 48 | 2,844
intraductal papillary-mucinous carcinoma (IPMC) 46 | 2,988
ulcerative colitis 46 | 2,087
Carcinoma 45 | 2,147
oligodendroglioma 45 | 2,849
interstitial cystitis 43 | 2,299
astrocytoma 42 | 1,493
pancreatic cancer 42 | 2,300
Multiple myeloma 41 | 1,327
Pick disease 39 | 1,893
juvenile dermatomyositis 39 | 1,189
breast carcinoma 38 | 1,614
ependymoma 38 | 2,514
Dermatitis 37 | 141
primitive neuroectodermal tumor 37 | 3,031
Behcet's syndrome 36 | 50
Nephritis 36 | 63
ductal carcinoma in situ 36 | 1,745
Congenital adrenal hyperplasia 35 | 74
Kidney disease 35 | 397
Multiple Sclerosis 35 | 498
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Synovitis 35 | 72
Takayasu's arteritis 35 | 54
drug-induced hepatitis 35 | 44
tuberculosis 34 | 1,563
adult high grade glioma 32 | 2,148
cystic fibrosis 32 | 1,670
group 4 medulloblastoma 32 | 1,875
pancreatic ductal adenocarcinoma liver metastasis 32 | 1,795
astrocytic glioma 30 | 2,241
posterior fossa group A ependymoma 30 | 1,511
Liver disease 29 | 219
pituitary cancer 29 | 1,972
Hemochromatosis 27 | 55
Anemia 26 | 252
primary pancreatic ductal adenocarcinoma 26 | 1,271
cutaneous lupus erythematosus 25 | 1,056
primary Sjogren syndrome 25 | 788
Hepatitis B 24 | 103
Leprosy 24 | 77
acute quadriplegic myopathy 23 | 1,157
gastric carcinoma 23 | 832
medulloblastoma 23 | 1,524
Birdshot chorioretinopathy 22 | 23
Neurodegenerative disease 22 | 383
Skin disease 22 | 65
group 3 medulloblastoma 22 | 2,254
posterior fossa group B ependymoma 22 | 1,530
Obesity 21 | 616
Primary immunodeficiency disease 21 | 52
Waldenstrons macroglobulinemia 21 | 764
esophageal adenocarcinoma 21 | 737
sonic hedgehog group medulloblastoma 21 | 1,482
Atherosclerosis 20 | 275
adrenocortical carcinoma 19 | 1,427
atypical teratoid/rhabdoid tumor 19 | 1,095
Alzheimer's disease 18 | 644
colon cancer 18 | 1,475
Coronary artery disease 17 | 240
active Crohn's disease 17 | 918
Duchenne muscular dystrophy 16 | 602
aldosterone-producing adenoma 16 | 664
mucosa-associated lymphoid tissue lymphoma 16 | 480
pre-eclampsia 16 | 67
Stomach Neoplasms 15 | 282
hereditary spastic paraplegia 15 | 313
spina bifida 15 | 1,064

Tissue

Digestive Tract 294 | 18,472
Endocrine System 294 | 18,511
Female tissues 294 | 18,646
Male tissues 294 | 17,968
Nervous System 294 | 18,560
Respiratory system 294 | 17,483
Urinary Tract 294 | 18,443
Cardiovascular System 293 | 17,957
Liver and Pancreas 293 | 18,135
Blood and immune system 292 | 17,994
Skin and soft tissues 287 | 18,114

Target Family

Non-IDG 265 | 11,969
Enzyme 56 | 4,146
Kinase 17 | 634
GPCR 12 | 408
Ion Channel 6 | 341
Transporter 6 | 473

Compartment GO Term

Early endosome 362 | 362
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
High affinity nerve growth factor receptor NTRK1 Tchem Kinase -3.03552 1003.4 1000
Rab15 effector protein REP15 Tbio Non-IDG -0.44863 2.71 15
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.87358 1568.8 0
Zinc finger protein RFP TRIM27 Tbio Non-IDG -1.50884 32.8 154
Pro-epidermal growth factor EGF Tbio Non-IDG -3.74596 4837.7 851
Low-density lipoprotein receptor LDLR Tchem Non-IDG -3.04462 893.1 512
RUN and FYVE domain-containing protein 1 RUFY1 Tbio Non-IDG -0.55207 5.48 142
HLA class I histocompatibility antigen, A-80 alpha chain HLA-A Tbio Non-IDG -2.40709 4042.7 0
Proteinase-activated receptor 1 F2R Tclin GPCR -2.76897 534.6 399
Sorting nexin-12 SNX12 Tbio Non-IDG -0.22432 2.17 135