Development Level

Tbio 305 | 11,445
Tchem 46 | 1,598
Tdark 34 | 6,588
Tclin 15 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37
Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 21 | 979
preweaning lethality, incomple... 12 | 499
abnormal embryo size 7 | 220
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 6 | 278
abnormal bone structure 5 | 187
decreased body weight 5 | 161
decreased bone mineral density 5 | 126
decreased circulating glucose ... 5 | 126
decreased mean corpuscular hem... 5 | 50
hypoactivity 5 | 132
increased circulating alkaline... 5 | 122
increased circulating choleste... 5 | 66
increased mean corpuscular vol... 5 | 92
abnormal behavior 4 | 298
decreased circulating HDL chol... 4 | 68
decreased circulating choleste... 4 | 93
decreased prepulse inhibition 4 | 82
enlarged heart 4 | 210
hydrometra 4 | 53
increased circulating HDL chol... 4 | 80
increased fasted circulating g... 4 | 76
increased neutrophil cell numb... 4 | 46
small superior vagus ganglion 4 | 74
abnormal craniofacial morpholo... 3 | 33
abnormal seminal vesicle morph... 3 | 114
abnormal sleep behavior 3 | 70
decreased bone mineral content 3 | 151
decreased circulating LDL chol... 3 | 38
decreased circulating serum al... 3 | 82
decreased grip strength 3 | 116
decreased leukocyte cell numbe... 3 | 73
decreased lymphocyte cell numb... 3 | 83
decreased total body fat amoun... 3 | 207
edema 3 | 59
embryonic growth retardation 3 | 106
increased circulating LDL chol... 3 | 13
increased circulating serum al... 3 | 22
increased circulating total pr... 3 | 28
increased heart weight 3 | 62
increased total body fat amoun... 3 | 134
abnormal gait 2 | 69
abnormal heart morphology 2 | 162
abnormal hindbrain morphology 2 | 10
abnormal kidney morphology 2 | 65
abnormal midbrain morphology 2 | 10
abnormal neural tube closure 2 | 46
abnormal retina morphology 2 | 71
abnormal skin morphology 2 | 50
abnormal thoracic cage shape 2 | 3
abnormal tooth morphology 2 | 24
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
decreased circulating alanine ... 2 | 47
decreased circulating alkaline... 2 | 46
decreased circulating aspartat... 2 | 34
decreased circulating triglyce... 2 | 79
decreased mean corpuscular vol... 2 | 79
decreased total retina thickne... 2 | 17
decreased vertical activity 2 | 208
enlarged spleen 2 | 41
improved glucose tolerance 2 | 79
increased circulating calcium ... 2 | 34
increased circulating chloride... 2 | 41
increased circulating free fat... 2 | 20
increased circulating iron lev... 2 | 30
increased eosinophil cell numb... 2 | 11
increased erythrocyte cell num... 2 | 39
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased mean corpuscular hem... 2 | 96
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
pallor 2 | 34
premature death 2 | 5
short tibia 2 | 97
tremors 2 | 39
abnormal body wall morphology 1 | 9
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal motor capabilities-co... 1 | 5
abnormal vertebrae morphology 1 | 18
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating bilirubi... 1 | 19
decreased circulating potassiu... 1 | 20
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
increased anti-nuclear antigen... 1 | 19
increased body length 1 | 32
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating amylase ... 1 | 25
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased red blood cell distr... 1 | 34
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
small thymus 1 | 16

Disease

Carcinoma 253 | 11,493
ovarian cancer 204 | 8,520
psoriasis 195 | 6,694
osteosarcoma 162 | 7,950
Cancer 145 | 2,499
glioblastoma 135 | 5,792
medulloblastoma, large-cell 135 | 6,241
diabetes mellitus 105 | 1,728
lung cancer 103 | 4,740
atypical teratoid / rhabdoid tumor 100 | 5,112
ependymoma 86 | 4,679
Astrocytoma, Pilocytic 74 | 3,081
invasive ductal carcinoma 74 | 2,951
Ankylosing spondylitis 72 | 140
Breast cancer 72 | 3,578
adult high grade glioma 72 | 3,801
Behcet's disease 71 | 89
malignant mesothelioma 71 | 3,232
Arthritis 69 | 290
Kidney cancer 69 | 2,613
dermatomyositis 68 | 966
tuberculosis 68 | 2,010
non-small cell lung cancer 65 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 64 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 64 | 3,291
Hypersensitivity reaction type II disease 63 | 253
Rheumatoid arthritis 63 | 1,191
subependymal giant cell astrocytoma 63 | 2,287
Acquired immunodeficiency syndrome 60 | 197
lung adenocarcinoma 60 | 2,716
lung carcinoma 60 | 2,843
Uveitis 58 | 103
Human immunodeficiency virus infectious disease 57 | 138
pancreatic cancer 57 | 2,398
Herpes zoster 56 | 68
Juvenile rheumatoid arthritis 56 | 111
intraductal papillary-mucinous carcinoma (IPMC) 56 | 2,989
oligodendroglioma 55 | 2,850
group 3 medulloblastoma 54 | 4,104
Stevens-Johnson syndrome 53 | 92
Psoriatic arthritis 49 | 86
interstitial cystitis 48 | 2,312
ulcerative colitis 47 | 1,819
astrocytic glioma 46 | 2,597
primitive neuroectodermal tumor 46 | 3,035
Pick disease 45 | 1,894
breast carcinoma 44 | 1,638
Multiple myeloma 43 | 1,332
juvenile dermatomyositis 43 | 1,187
ductal carcinoma in situ 42 | 1,745
Dermatitis 41 | 157
Schizophrenia 40 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 40 | 1,962
Kidney disease 39 | 430
group 4 medulloblastoma 39 | 1,855
pituitary cancer 38 | 1,972
Behcet's syndrome 37 | 50
Multiple Sclerosis 37 | 540
astrocytoma 37 | 1,146
Synovitis 36 | 78
cystic fibrosis 36 | 1,696
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
Takayasu's arteritis 35 | 53
drug-induced hepatitis 35 | 44
Autosomal recessive predisposition 32 | 1,442
Liver disease 31 | 237
primary pancreatic ductal adenocarcinoma 30 | 1,109
Neurodegenerative disease 29 | 414
Alzheimer's disease 28 | 658
Anemia 28 | 365
adrenocortical carcinoma 28 | 1,428
cutaneous lupus erythematosus 28 | 1,057
Hemochromatosis 27 | 54
esophageal adenocarcinoma 27 | 737
pediatric high grade glioma 27 | 1,064
primary Sjogren syndrome 27 | 735
Obesity 26 | 678
Liver Cirrhosis, Experimental 25 | 769
gastric carcinoma 25 | 807
Hepatitis B 24 | 108
Leprosy 24 | 73
Atherosclerosis 23 | 291
Intellectual disability 23 | 1,016
acute quadriplegic myopathy 23 | 1,158
colon cancer 23 | 1,478
Birdshot chorioretinopathy 22 | 23
Skin disease 22 | 66
Waldenstrons macroglobulinemia 22 | 765
Bipolar Disorder 21 | 666
Primary immunodeficiency disease 21 | 54
active Crohn's disease 21 | 922
Epilepsy 20 | 792
spina bifida 20 | 1,074
Hypertension 19 | 396
nasopharyngeal carcinoma 19 | 1,058
mucosa-associated lymphoid tissue lymphoma 18 | 484
pancreatic carcinoma 18 | 562

Tissue

Digestive Tract 322 | 17,369
Endocrine System 322 | 18,159
Female tissues 320 | 17,400
Liver and Pancreas 319 | 16,750
Male tissues 318 | 17,142
Skin and soft tissues 318 | 17,230
Blood and immune system 316 | 16,909
Nervous System 316 | 16,725
Urinary Tract 315 | 16,678
Respiratory system 313 | 16,393
Cardiovascular System 304 | 15,192

Target Family

Non-IDG 290 | 12,091
Enzyme 63 | 4,145
Kinase 18 | 634
GPCR 12 | 408
Ion Channel 9 | 344
Transporter 7 | 473
Transcription Factor 1 | 1,400

Compartment GO Term

Early endosome 400 | 400
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
MAGE-like protein 2 MAGEL2 Tbio Non-IDG -1.95242 83.8 86
Ras-related protein Rab-20 RAB20 Tbio Enzyme -0.97781 11.5 171
TBC1 domain family member 3L TBC1D3L Tdark Non-IDG 0.00000 2
Endophilin-A2 SH3GL1 Tbio Non-IDG -2.15479 134.2 257
Ras-related protein Rab-22A RAB22A Tbio Enzyme -1.40824 19.7 123
Sorting nexin-13 SNX13 Tbio Non-IDG -0.67169 5.24 65
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
Endothelin-converting enzyme 1 ECE1 Tchem Enzyme -2.56360 355.0 278
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275