Development Level

Tbio 16 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 4 | 979
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal esophagus morphology 1 | 5
abnormal kidney morphology 1 | 65
abnormal tooth morphology 1 | 24
abnormal vertebral arch morpho... 1 | 9
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
enlarged gallbladder 1 | 2
enlarged kidney 1 | 14
enlarged spleen 1 | 41
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
prenatal lethality prior to he... 1 | 87
tremors 1 | 39

Disease

ovarian cancer 13 | 8,520
Carcinoma 12 | 11,493
osteosarcoma 9 | 7,950
glioblastoma 7 | 5,792
atypical teratoid / rhabdoid tumor 6 | 5,112
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
Multiple myeloma 4 | 1,332
ependymoma 4 | 4,679
Breast cancer 3 | 3,578
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
lung cancer 3 | 4,740
oligodendroglioma 3 | 2,850
Astrocytoma, Pilocytic 2 | 3,081
Bipolar Disorder 2 | 666
Failure to gain weight 2 | 365
Pediatric failure to thrive 2 | 365
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma 2 | 720
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primitive neuroectodermal tumor 2 | 3,035
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Acne 1 | 52
Adenoma 1 | 167
Anxiety 1 | 136
Anxiety disease 1 | 113
Blepharoptosis 1 | 231
Brachydactyly 1 | 156
Brain Diseases 1 | 24
Breast Neoplasms 1 | 445
Cerebral atrophy 1 | 178
Congenital deafness 1 | 185
Congenital hypothyroidism 1 | 26
Conversion disorder 1 | 6
Cushing's syndrome 1 | 48
Deafness 1 | 198
Decreased projection of maxilla 1 | 66
Deficiency of upper jaw bones 1 | 66
Degenerative brain disorder 1 | 100
Delayed myelination 1 | 22
Developmental Disabilities 1 | 23
Ecchymosis 1 | 66
Familial cancer of breast 1 | 12
Fatigue 1 | 182
Foramen Ovale, Patent 1 | 10
Frequent fractures 1 | 53
Gastrointestinal system disease 1 | 54
Generalized hirsutism 1 | 36
Global developmental delay, severe 1 | 47
Hearing Loss, Partial 1 | 185
Human immunodeficiency virus infectious disease 1 | 138
Hypokalemia 1 | 52
Hypoplasia of corpus callosum 1 | 90
Hypoplasia of the maxilla 1 | 66
Hypotrophic maxilla 1 | 66
Idiopathic scoliosis 1 | 31
Immunologic Deficiency Syndromes 1 | 113
Increased fracture rate 1 | 53
Increased tendency to bruise 1 | 66
Infertility 1 | 188
Kaposi's sarcoma 1 | 22
Klippel-Feil syndrome 1 | 15
Lipodystrophy 1 | 40
Low Birth Weights 1 | 69
MAJOR AFFECTIVE DISORDER 2 1 | 22
Major Depressive Disorder 1 | 301
Maxillary retrognathia 1 | 66
Menorrhagia 1 | 25
Microcephaly 1 | 166
Micronychia (disorder) 1 | 24
Myoclonus 1 | 74
Nager acrofacial dysostosis 1 | 21
Nephrolithiasis 1 | 56
Obesity, Abdominal 1 | 24
Osteoporosis 1 | 363
Pituitary adenoma 1 | 38
Prenatal onset 1 | 139
Progressive microcephaly 1 | 32
Retrusion of upper jaw bones 1 | 66
Round face 1 | 45
Round, full face 1 | 45
Severe psychomotor retardation 1 | 47
Short distal phalanges 1 | 50
Small for gestational age (disorder) 1 | 69
Supratentorial atrophy 1 | 94
Thanatophoric dysplasia 1 | 7
Thin skin 1 | 47
Unipolar Depression 1 | 250
Varying degree of multiple fractures 1 | 53
Wide nose 1 | 35
hearing impairment 1 | 199
sarcoidosis 1 | 370
tuberculosis and treatment for 3 months 1 | 179
tuberculosis and treatment for 6 months 1 | 409

Tissue

Blood and immune system 18 | 16,909
Cardiovascular System 18 | 15,192
Digestive Tract 18 | 17,369
Endocrine System 18 | 18,159
Female tissues 18 | 17,400
Liver and Pancreas 18 | 16,750
Male tissues 18 | 17,142
Nervous System 18 | 16,725
Respiratory system 18 | 16,393
Skin and soft tissues 18 | 17,230
Urinary Tract 18 | 16,678

Target Family

Non-IDG 12 | 12,091
Enzyme 6 | 4,145

Compartment GO Term

ESCRT-0 complex 18 | 18
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG -1.39658 35.6 64
Secretory carrier-associated membrane protein 3 SCAMP3 Tbio Non-IDG -1.02982 12.0 108
E3 ubiquitin-protein ligase RNF103 RNF103 Tbio Enzyme -1.95102 35.6 76
Speckle-type POZ protein-like SPOPL Tdark Non-IDG -0.40512 2.41 91
Tyrosine-protein phosphatase non-receptor type 23 PTPN23 Tbio Enzyme -1.41527 29.6 103
TOM1-like protein 1 TOM1L1 Tbio Non-IDG -0.88256 9.68 177
Charged multivesicular body protein 6 CHMP6 Tbio Non-IDG -1.35757 22.3 120
RING finger protein 11 RNF11 Tbio Non-IDG -1.28809 23.4 120
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tbio Enzyme -1.72968 58.3 209