Development Level

Tbio 44 | 11,445
Tdark 3 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to o... 3 | 239
hypoactivity 3 | 132
abnormal behavior 2 | 298
abnormal body wall morphology 2 | 9
decreased circulating free fat... 2 | 31
increased circulating HDL chol... 2 | 80
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal kidney morphology 1 | 65
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal skin morphology 1 | 50
absent startle reflex 1 | 24
cataract 1 | 92
decreased body weight 1 | 161
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating sodium l... 1 | 22
decreased leukocyte cell numbe... 1 | 73
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased or absent threshold ... 1 | 101
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
protruding tongue 1 | 3

Disease

ovarian cancer 35 | 8,520
Carcinoma 19 | 11,493
osteosarcoma 18 | 7,950
psoriasis 15 | 6,694
glioblastoma 13 | 5,792
lung cancer 11 | 4,740
Multiple myeloma 10 | 1,332
medulloblastoma, large-cell 10 | 6,241
atypical teratoid / rhabdoid tumor 9 | 5,112
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
malignant mesothelioma 8 | 3,232
non-small cell lung cancer 8 | 2,890
Astrocytoma, Pilocytic 7 | 3,081
Breast cancer 7 | 3,578
ependymoma 7 | 4,679
group 3 medulloblastoma 7 | 4,104
oligodendroglioma 7 | 2,850
acute quadriplegic myopathy 6 | 1,158
breast carcinoma 6 | 1,638
invasive ductal carcinoma 6 | 2,951
spina bifida 6 | 1,074
Cancer 5 | 2,499
Neurodegenerative disease 5 | 414
Pick disease 5 | 1,894
astrocytic glioma 5 | 2,597
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
lung adenocarcinoma 5 | 2,716
tuberculosis 5 | 2,010
Kidney cancer 4 | 2,613
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
diabetes mellitus 4 | 1,728
ductal carcinoma in situ 4 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Endometriosis 3 | 540
Failure to gain weight 3 | 365
Hyperreflexia 3 | 209
Hypertensive disease 3 | 292
Pediatric failure to thrive 3 | 365
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
primary pancreatic ductal adenocarcinoma 3 | 1,109
primitive neuroectodermal tumor 3 | 3,035
progressive supranuclear palsy 3 | 676
Absent reflex 2 | 92
Absent tendon reflex 2 | 92
Adenoma 2 | 167
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Anxiety 2 | 136
Anxiety disease 2 | 113
Atopic dermatitis 2 | 952
Babinski Reflex 2 | 100
Breast Neoplasms 2 | 445
Cerebral atrophy 2 | 178
Chronic Lymphocytic Leukemia 2 | 262
Congenital pes cavus 2 | 88
Decreased tendon reflex 2 | 122
Dementia 2 | 175
Depressive disorder 2 | 409
Dull intelligence 2 | 645
Fatigue 2 | 182
Hypertension 2 | 396
Hypoplasia of corpus callosum 2 | 90
Increase in blood pressure 2 | 119
Memory impairment 2 | 40
Mental deficiency 2 | 645
Muscle Spasticity 2 | 195
Myocardial Ischemia 2 | 169
Myoclonus 2 | 74
Ovarian Neoplasms 2 | 102
Paraplegia 2 | 74
Physical aggression 2 | 76
Poor school performance 2 | 645
Prenatal onset 2 | 139
Prostatic Neoplasms 2 | 495
Reflex, Deep Tendon, Absent 2 | 92
Rheumatoid arthritis 2 | 1,191
Social disinhibition 2 | 14
Urinary Incontinence 2 | 50
Waldenstrons macroglobulinemia 2 | 765
acute myeloid leukemia 2 | 783
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
interstitial lung disease 2 | 298
medulloblastoma 2 | 720
ovarian neoplasm 2 | 99

Tissue

Blood and immune system 49 | 16,909
Cardiovascular System 49 | 15,192
Digestive Tract 49 | 17,369
Endocrine System 49 | 18,159
Female tissues 49 | 17,400
Liver and Pancreas 49 | 16,750
Male tissues 49 | 17,142
Nervous System 49 | 16,725
Respiratory system 49 | 16,393
Skin and soft tissues 49 | 17,230
Urinary Tract 49 | 16,678

Target Family

Non-IDG 41 | 12,091
Enzyme 7 | 4,145
Kinase 1 | 634

Compartment GO Term

ESCRT complex 49 | 49
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Charged multivesicular body protein 7 CHMP7 Tbio Non-IDG -0.61033 3.61 30
MIT domain-containing protein 1 MITD1 Tbio Non-IDG -0.25556 2.10 59
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG -1.39658 35.6 64
Programmed cell death 6-interacting protein PDCD6IP Tbio Non-IDG -1.59404 35.1 216
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
Ras-related protein Rab-7a RAB7A Tbio Enzyme -2.66545 435.4 248
Calpain-7 CAPN7 Tbio Non-IDG -1.51078 32.0 65
Centrosomal protein of 55 kDa CEP55 Tbio Non-IDG -1.49634 36.2 207
Charged multivesicular body protein 2b CHMP2B Tbio Non-IDG -1.71624 54.4 193