Development Level

Tbio 14 | 11,445

IMPC Phenotype

preweaning lethality, complete... 6 | 979
embryonic lethality prior to o... 3 | 239
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
cataract 1 | 92
decreased circulating free fat... 1 | 31
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 9 | 8,520
osteosarcoma 6 | 7,950
Carcinoma 4 | 11,493
Multiple myeloma 4 | 1,332
Breast cancer 3 | 3,578
atypical teratoid / rhabdoid tumor 3 | 5,112
Cancer 2 | 2,499
Kaposi's sarcoma 2 | 22
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
psoriasis 2 | 6,694
Absent speech 1 | 43
Amyotrophic lateral sclerosis 1 | 451
Arthritis, Juvenile 1 | 126
Astigmatism 1 | 54
Attention deficit hyperactivity disorder 1 | 278
Autosomal recessive predisposition 1 | 1,442
Axial hypotonia 1 | 46
Breast Neoplasms 1 | 445
Bullous pemphigoid 1 | 18
Cerebellar Hypoplasia 1 | 61
Chorea 1 | 29
Choreatic disease 1 | 52
Cicatricial pemphigoid 1 | 5
Cognitive delay 1 | 608
Complement component 3 deficiency 1 | 8
Congenital clubfoot 1 | 109
Congenital pes cavus 1 | 88
Dull intelligence 1 | 645
Epidermolysis bullosa acquisita 1 | 10
Epidermolysis bullosa dystrophica 1 | 6
Esotropia 1 | 31
Familial cancer of breast 1 | 12
Fragile X syndrome 1 | 34
Gastroparesis 1 | 22
Global developmental delay 1 | 608
Herpes gestationis 1 | 6
Human immunodeficiency virus infectious disease 1 | 138
Hyperopia 1 | 70
Hyperreflexia 1 | 209
Hypoplasia of corpus callosum 1 | 90
Hypoplasia of the brainstem 1 | 22
Intellectual disability 1 | 1,016
Juvenile arthritis 1 | 126
Kidney cancer 1 | 2,613
Klippel-Feil syndrome 1 | 15
Low intelligence 1 | 645
Lung adenoma 1 | 8
Mental Retardation 1 | 645
Mental and motor retardation 1 | 608
Mental deficiency 1 | 645
Muscle Spasticity 1 | 195
Myopia 1 | 176
Neurodegenerative disease 1 | 414
PONTOCEREBELLAR HYPOPLASIA, TYPE 8 1 | 1
Pick disease 1 | 1,894
Pneumonia 1 | 174
Pontocerebellar hypoplasia 1 | 36
Poor school performance 1 | 645
Poor speech 1 | 37
Postnatal microcephaly 1 | 24
Prenatal onset 1 | 139
Problems speaking 1 | 37
Rheumatoid arthritis 1 | 1,191
Serous cystadenocarcinoma 1 | 2
Talipes valgus 1 | 3
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
astrocytic glioma 1 | 2,597
breast carcinoma 1 | 1,638
dermatomyositis 1 | 966
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
group 3 medulloblastoma 1 | 4,104
hepatocellular carcinoma 1 | 547
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
invasive ductal carcinoma 1 | 2,951
lung adenocarcinoma 1 | 2,716
non primary Sjogren syndrome sicca 1 | 891
non-small cell lung cancer 1 | 2,890
nonverbal 1 | 43
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,962
pontocerebellar hypoplasia type 8 1 | 1
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Non-IDG 11 | 12,091
Enzyme 2 | 4,145
Epigenetic 1 | 242

Compartment GO Term

ESCRT II complex 14 | 14
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Charged multivesicular body protein 7 CHMP7 Tbio Non-IDG -0.61033 3.61 30
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG -1.39658 35.6 64
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.17768 16.3 29
E3 ubiquitin-protein ligase RNF103 RNF103 Tbio Enzyme -1.95102 35.6 76
Tyrosine-protein phosphatase non-receptor type 23 PTPN23 Tbio Enzyme -1.41527 29.6 103
Charged multivesicular body protein 6 CHMP6 Tbio Non-IDG -1.35757 22.3 120
Charged multivesicular body protein 2a CHMP2A Tbio Non-IDG -2.45155 278.6 88
Vacuolar protein-sorting-associated protein 25 VPS25 Tbio Non-IDG -1.21447 17.7 154