Development Level

Tbio 22 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal embryo size 3 | 220
embryonic lethality prior to o... 3 | 239
abnormal body wall morphology 2 | 9
hypoactivity 2 | 132
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal craniofacial morpholo... 1 | 33
abnormal kidney morphology 1 | 65
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic lethality prior to t... 1 | 278
enlarged seminal vesicle 1 | 10
enlarged spleen 1 | 41
enlarged testis 1 | 6
impaired glucose tolerance 1 | 75
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
protruding tongue 1 | 3

Disease

ovarian cancer 15 | 8,520
osteosarcoma 10 | 7,950
psoriasis 10 | 6,694
Carcinoma 8 | 11,493
Multiple myeloma 4 | 1,332
lung cancer 4 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
tuberculosis 4 | 2,010
Breast cancer 3 | 3,578
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
glioblastoma 3 | 5,792
Astrocytoma, Pilocytic 2 | 3,081
Cancer 2 | 2,499
Kaposi's sarcoma 2 | 22
Kidney cancer 2 | 2,613
Neurodegenerative disease 2 | 414
acute myeloid leukemia 2 | 783
adult high grade glioma 2 | 3,801
astrocytoma 2 | 1,146
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
subependymal giant cell astrocytoma 2 | 2,287
Absent speech 1 | 43
Arthritis, Juvenile 1 | 126
Astigmatism 1 | 54
Autosomal recessive Robinow syndrome 1 | 27
Axial hypotonia 1 | 46
Bipolar Disorder 1 | 666
Breast Neoplasms 1 | 445
Chancroid 1 | 8
Charcot-Marie-Tooth disease type 1C 1 | 5
Chorea 1 | 29
Choreatic disease 1 | 52
Congenital clubfoot 1 | 109
Congenital heart disease 1 | 93
Congenital pes cavus 1 | 88
Danon disease 1 | 8
Epidermolysis bullosa acquisita 1 | 10
Esotropia 1 | 31
Familial cancer of breast 1 | 12
Fragile X syndrome 1 | 34
Human immunodeficiency virus infectious disease 1 | 138
Hyperopia 1 | 70
Hyperreflexia 1 | 209
Hypertension 1 | 396
Hypoplasia of corpus callosum 1 | 90
Hypoplasia of the brainstem 1 | 22
Idiopathic scoliosis 1 | 31
Intermediate coronary syndrome 1 | 11
Juvenile arthritis 1 | 126
Keloid 1 | 37
Klippel-Feil syndrome 1 | 15
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Liddle syndrome 1 | 14
Lung adenoma 1 | 8
Multiple Sclerosis 1 | 540
Muscle Spasticity 1 | 195
Myocardial Infarction 1 | 151
Myocardial Ischemia 1 | 169
Myopia 1 | 176
PONTOCEREBELLAR HYPOPLASIA, TYPE 8 1 | 1
Pick disease 1 | 1,894
Pontocerebellar hypoplasia 1 | 36
Poor speech 1 | 37
Postnatal microcephaly 1 | 24
Prenatal onset 1 | 139
Prion disease 1 | 16
Problems speaking 1 | 37
Pseudohypoaldosteronism 1 | 23
Secondary progressive multiple sclerosis 1 | 10
Skin disease 1 | 66
Stevens-Johnson syndrome 1 | 92
Talipes valgus 1 | 3
Vascular disease 1 | 319
Williams-Beuren syndrome 1 | 50
adrenocortical carcinoma 1 | 1,428
astrocytic glioma 1 | 2,597
dermatomyositis 1 | 966
hereditary spastic paraplegia 1 | 318
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
nonverbal 1 | 43
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064
pontocerebellar hypoplasia type 8 1 | 1
primary open angle glaucoma 1 | 16
progressive supranuclear palsy 1 | 676
spina bifida 1 | 1,074

Tissue

Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678

Target Family

Non-IDG 19 | 12,091
Enzyme 6 | 4,145

Compartment GO Term

ESCRT I complex 25 | 25
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tumor susceptibility gene 101 protein TSG101 Tbio Non-IDG -2.47780 298.9 332
Charged multivesicular body protein 3 CHMP3 Tbio Non-IDG -1.39658 35.6 64
Charged multivesicular body protein 1a CHMP1A Tbio Non-IDG -1.15571 14.9 161
Charged multivesicular body protein 4a CHMP4A Tbio Non-IDG -1.17768 16.3 29
E3 ubiquitin-protein ligase RNF103 RNF103 Tbio Enzyme -1.95102 35.6 76
Phospholipid phosphatase 6 PLPP6 Tbio Enzyme -1.30463 23.2 111
Ubiquitin-associated protein 1-like UBAP1L Tdark Non-IDG 0.00000 6
Tyrosine-protein phosphatase non-receptor type 23 PTPN23 Tbio Enzyme -1.41527 29.6 103
E3 ubiquitin-protein ligase NEDD4 NEDD4 Tchem Enzyme -2.44046 259.8 167
Charged multivesicular body protein 6 CHMP6 Tbio Non-IDG -1.35757 22.3 120