Development Level

Tbio 13 | 11,445
Tchem 2 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal placement of pupils 1 | 6
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
corneal opacity 1 | 32
increased bone mineral density 1 | 72
increased hemoglobin content 1 | 45
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 12 | 11,493
osteosarcoma 11 | 7,950
Fanconi anemia 8 | 56
Bloom syndrome 7 | 29
Breast cancer 7 | 3,578
Xeroderma pigmentosum group F 7 | 22
group 3 medulloblastoma 7 | 4,104
Xeroderma pigmentosum 6 | 43
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Cancer 5 | 2,499
Cockayne syndrome 5 | 60
Autosomal recessive predisposition 4 | 1,442
Cataract 3 | 297
Cognitive delay 3 | 608
Dull intelligence 3 | 645
Electroencephalogram abnormal 3 | 101
Failure to gain weight 3 | 365
Global developmental delay 3 | 608
Hypogonadism 3 | 173
Intellectual disability 3 | 1,016
Lens Opacities 3 | 231
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental and motor retardation 3 | 608
Mental deficiency 3 | 645
Pediatric failure to thrive 3 | 365
Photosensitive trichothiodystrophy 3 | 30
Photosensitivity of skin 3 | 51
Poor school performance 3 | 645
Sensorineural Hearing Loss (disorder) 3 | 284
Small head 3 | 374
atypical teratoid / rhabdoid tumor 3 | 5,112
ductal carcinoma in situ 3 | 1,745
glioblastoma 3 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
non-small cell lung cancer 3 | 2,890
Arsenic Poisoning 2 | 62
Arthralgia 2 | 90
Atopic dermatitis 2 | 952
Basal cell carcinoma 2 | 54
Cerebral atrophy 2 | 178
Conjunctival telangiectasis 2 | 14
Dental abnormalities 2 | 60
Developmental regression 2 | 95
Dry skin 2 | 75
Enophthalmos 2 | 75
Erythema 2 | 58
Fatigue 2 | 182
Fever 2 | 138
Flushing 2 | 60
Freckles 2 | 33
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hyperkeratosis 2 | 50
Impaired cognition 2 | 96
Keratitis 2 | 62
Kidney cancer 2 | 2,613
Liver Dysfunction 2 | 99
Loss of developmental milestones 2 | 95
Low Vision 2 | 174
Mental deterioration in childhood 2 | 95
Mental impairment 2 | 95
Muscle Spasticity 2 | 195
Neoplasm Metastasis 2 | 168
Neoplasms, Germ Cell and Embryonal 2 | 15
Neurodevelopmental regression 2 | 95
Peripheral Neuropathy 2 | 134
Phenotypic variability 2 | 150
Poor coordination 2 | 11
Psychomotor regression 2 | 95
Psychomotor regression beginning in infancy 2 | 95
Psychomotor regression in infants 2 | 95
Psychomotor regression, progressive 2 | 95
Strabismus 2 | 270
Sunken eyes 2 | 63
Telangiectasia of the skin 2 | 39
Testicular Neoplasms 2 | 6
Thin skin 2 | 47
Tooth Abnormalities 2 | 69
Visual Impairment 2 | 174
Waldenstrons macroglobulinemia 2 | 765
Xerosis 2 | 75
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
nasopharyngeal carcinoma 2 | 1,058
pancreatic cancer 2 | 2,398
pancreatic carcinoma 2 | 562
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group B ependymoma 2 | 416
primitive neuroectodermal tumor 2 | 3,035

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393

Target Family

Non-IDG 8 | 12,091
Enzyme 7 | 4,145
Transporter 1 | 473

Compartment GO Term

ERCC4-ERCC1 complex 16 | 16
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosyl-DNA phosphodiesterase 1 TDP1 Tchem Enzyme -2.09041 139.4 210
Structure-specific endonuclease subunit SLX4 SLX4 Tbio Enzyme -1.68794 61.7 56
Uncharacterized protein C9orf84 C9orf84 Tdark Non-IDG 0.30 0.50 27
DNA cross-link repair 1A protein DCLRE1A Tbio Non-IDG -1.94675 90.4 92
Crossover junction endonuclease MUS81 MUS81 Tbio Enzyme -2.06893 119.1 95
UV excision repair protein RAD23 homolog B RAD23B Tbio Non-IDG -1.99412 96.8 313
Mitochondrial ornithine transporter 1 SLC25A15 Tbio Transporter -2.21589 161.5 45
DNA repair protein complementing XP-A cells XPA Tbio Non-IDG -2.87504 739.6 379
Structure-specific endonuclease subunit SLX1 SLX1B Tbio Enzyme -1.16189 11.6 42
Flap endonuclease 1 FEN1 Tchem Enzyme -2.79171 617.0 406