Development Level

Tbio 8 | 10,625
Tchem 3 | 1,890
Tdark 1 | 7,003

IMPC Term

abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal placement of pupils 1 | 4
abnormal spleen morphology 1 | 36
anophthalmia 1 | 20
corneal opacity 1 | 25
decreased body weight 1 | 174
increased bone mineral density 1 | 52
increased hemoglobin content 1 | 45
narrow eye opening 1 | 15
thrombocytopenia 1 | 46

Disease

osteosarcoma 9 | 7,933
Fanconi's anemia 6 | 50
Xeroderma pigmentosum 6 | 41
ovarian cancer 6 | 8,492
Cancer 5 | 2,346
Cockayne syndrome 5 | 54
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
medulloblastoma, large-cell 5 | 6,234
Bloom syndrome 4 | 30
Breast cancer 4 | 3,099
Photosensitive trichothiodystrophy 4 | 24
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
psoriasis 4 | 6,685
group 3 medulloblastoma 3 | 2,254
lung cancer 3 | 4,473
Aplastic anemia 2 | 19
Arsenic Poisoning 2 | 59
CAMFAK syndrome 2 | 4
COFS syndrome 2 | 4
Carcinoma 2 | 2,147
Cerebrooculofacioskeletal Syndrome 1 2 | 4
Fanconi Anemia 2 | 22
Micronuclei, Chromosome-Defective 2 | 20
Neoplasm Metastasis 2 | 138
Neoplasms, Germ Cell and Embryonal 2 | 13
Pena Shokeir syndrome Type 2 2 | 4
Peripheral Neuropathy 2 | 303
Progeria 2 | 22
Testicular Neoplasms 2 | 5
Xeroderma pigmentosum-Cockayne syndrome complex 2 | 4
atypical teratoid / rhabdoid tumor 2 | 4,369
ductal carcinoma in situ 2 | 1,745
esophageal atresia/tracheoesophageal fistula 2 | 19
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,714
malignant mesothelioma 2 | 3,163
nasopharyngeal carcinoma 2 | 1,056
non-small cell lung cancer 2 | 2,798
pancreatic cancer 2 | 2,300
pancreatic carcinoma 2 | 567
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
Adenocarcinoma of lung (disorder) 1 | 48
Anemia 1 | 252
Argininosuccinic aciduria 1 | 17
Ataxia with oculomotor apraxia type 1 1 | 5
Atopic dermatitis 1 | 944
Axonal neuropathy 1 | 17
Basal cell carcinoma 1 | 31
Bladder Neoplasm 1 | 109
COPD 1 | 116
Cataract 1 | 104
Cerebro-oculo-facio-skeletal syndrome 1 | 3
Cerebro-oculo-facio-skeletal syndrome 3 1 | 1
Cerebrooculofacioskeletal Syndrome 3 1 | 1
Chromosome Aberrations 1 | 15
Citrullinemia 1 | 13
Colorectal Neoplasms 1 | 217
Endometriosis 1 | 535
Fanconi anemia complementation group P 1 | 1
Fanconi anemia, complementation group P 1 | 1
HHH syndrome 1 | 1
Hyperargininemia 1 | 7
Hyperornithinemia-hyperammonemia-homocitrullinuria syndrome 1 | 1
Intestinal Neoplasms 1 | 11
Melanoma 1 | 261
Neurodegenerative disease 1 | 383
Neutropenia 1 | 78
Ollier disease 1 | 15
Ornithine carbamoyltransferase deficiency 1 | 13
Ornithine translocase deficiency 1 | 5
Seckel syndrome 1 | 35
Skin Neoplasms 1 | 49
Skin benign neoplasm 1 | 5
Spasmodic dystonia 1 | 1
Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1 | 1
Stomach Neoplasms 1 | 282
Thyroid Hormone Metabolism, Abnormal 1 | 2
Uterine Cervical Neoplasm 1 | 21
Vitelliform macular dystrophy 1 | 14
Waldenstrons macroglobulinemia 1 | 765
Werner syndrome 1 | 29
Xanthogranulomatous pyelonephritis 1 | 4
Xeroderma Pigmentosum, Complementation Group a 1 | 2
Xeroderma Pigmentosum, Type G/Cockayne Syndrome 1 | 1
Xeroderma pigmentosum complementation group A 1 | 1
Xeroderma pigmentosum complementation group G 1 | 1
Xeroderma pigmentosum, group A 1 | 1
Xeroderma pigmentosum, group G 1 | 1
active Crohn's disease 1 | 918
colon cancer 1 | 1,475
cystic fibrosis 1 | 1,670
gastric carcinoma 1 | 832
glioblastoma multiforme 1 | 347
hepatocellular carcinoma 1 | 550
non-small cell lung carcinoma 1 | 413
progressive supranuclear palsy 1 | 674
sonic hedgehog group medulloblastoma 1 | 1,482
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis and treatment for 3 months 1 | 327

Tissue

Blood and immune system 12 | 17,995
Cardiovascular System 12 | 17,958
Digestive Tract 12 | 18,473
Endocrine System 12 | 18,512
Female tissues 12 | 18,647
Liver and Pancreas 12 | 18,136
Male tissues 12 | 17,969
Nervous System 12 | 18,561
Respiratory system 12 | 17,484
Skin and soft tissues 12 | 18,115
Urinary Tract 12 | 18,444

Target Family

Enzyme 8 | 4,146
Non-IDG 3 | 11,969
Transporter 1 | 473

Compartment GO Term

ERCC4-ERCC1 complex 12 | 12
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosyl-DNA phosphodiesterase 1 TDP1 Tchem Enzyme -2.03905 126.5 179
Crossover junction endonuclease MUS81 MUS81 Tbio Enzyme -2.03597 106.6 73
Flap endonuclease 1 FEN1 Tchem Enzyme -2.77484 533.8 332
Mitochondrial ornithine transporter 1 SLC25A15 Tbio Transporter -2.19972 150.3 39
DNA repair protein complementing XP-A cells XPA Tbio Non-IDG -2.86072 674.6 301
DNA repair protein complementing XP-G cells ERCC5 Tchem Enzyme -2.05009 296.8 215
Structure-specific endonuclease subunit SLX4 SLX4 Tbio Enzyme -1.66660 54.9 35
DNA repair endonuclease XPF ERCC4 Tbio Enzyme -1.87081 252.5 195
Uncharacterized protein C9orf84 C9orf84 Tdark Non-IDG 0.30 0.20 29
Structure-specific endonuclease subunit SLX1 SLX1B Tbio Enzyme -1.14741 10.4 37