Development Level

Tbio 13 | 11,178
Tchem 2 | 1,885
Tdark 1 | 6,569

IMPC Phenotype

abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal eye size 1 | 7
abnormal placement of pupils 1 | 6
abnormal spleen morphology 1 | 55
anophthalmia 1 | 33
corneal opacity 1 | 32
increased bone mineral density 1 | 72
increased hemoglobin content 1 | 45
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 12 | 11,192
osteosarcoma 11 | 7,766
Fanconi anemia 8 | 56
Bloom syndrome 7 | 29
Breast cancer 7 | 3,469
Xeroderma pigmentosum group F 7 | 21
group 3 medulloblastoma 7 | 4,002
Xeroderma pigmentosum 6 | 42
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,204
lung cancer 6 | 4,607
malignant mesothelioma 6 | 3,135
medulloblastoma, large-cell 6 | 6,086
ovarian cancer 6 | 8,297
psoriasis 6 | 6,514
Cancer 5 | 2,388
Cockayne syndrome 5 | 59
Autosomal recessive predisposition 4 | 1,407
Cataract 3 | 290
Cognitive delay 3 | 596
Dull intelligence 3 | 634
Electroencephalogram abnormal 3 | 100
Failure to gain weight 3 | 359
Global developmental delay 3 | 596
Hypogonadism 3 | 169
Intellectual disability 3 | 998
Lens Opacities 3 | 227
Low intelligence 3 | 634
Melanoma 3 | 689
Mental Retardation 3 | 634
Mental and motor retardation 3 | 596
Mental deficiency 3 | 634
Pediatric failure to thrive 3 | 359
Photosensitive trichothiodystrophy 3 | 30
Photosensitivity of skin 3 | 51
Poor school performance 3 | 634
Sensorineural Hearing Loss (disorder) 3 | 281
Small head 3 | 366
atypical teratoid / rhabdoid tumor 3 | 4,971
ductal carcinoma in situ 3 | 1,686
glioblastoma 3 | 5,635
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,902
invasive ductal carcinoma 3 | 2,867
lung adenocarcinoma 3 | 2,627
non-small cell lung cancer 3 | 2,799
Arsenic Poisoning 2 | 60
Arthralgia 2 | 85
Atopic dermatitis 2 | 915
Basal cell carcinoma 2 | 54
Cerebral atrophy 2 | 175
Conjunctival telangiectasis 2 | 14
Dental abnormalities 2 | 57
Developmental regression 2 | 94
Dry skin 2 | 74
Enophthalmos 2 | 74
Erythema 2 | 57
Fatigue 2 | 176
Fever 2 | 136
Flushing 2 | 59
Freckles 2 | 33
Highly variable clinical phenotype 2 | 147
Highly variable phenotype and severity 2 | 147
Highly variable phenotype, even within families 2 | 147
Hyperkeratosis 2 | 50
Impaired cognition 2 | 95
Keratitis 2 | 60
Kidney cancer 2 | 2,548
Liver Dysfunction 2 | 97
Loss of developmental milestones 2 | 94
Low Vision 2 | 167
Mental deterioration in childhood 2 | 94
Mental impairment 2 | 95
Muscle Spasticity 2 | 192
Neoplasm Metastasis 2 | 160
Neoplasms, Germ Cell and Embryonal 2 | 15
Neurodevelopmental regression 2 | 94
Peripheral Neuropathy 2 | 131
Phenotypic variability 2 | 147
Poor coordination 2 | 11
Psychomotor regression 2 | 94
Psychomotor regression beginning in infancy 2 | 94
Psychomotor regression in infants 2 | 94
Psychomotor regression, progressive 2 | 94
Strabismus 2 | 265
Sunken eyes 2 | 62
Telangiectasia of the skin 2 | 38
Testicular Neoplasms 2 | 6
Thin skin 2 | 44
Tooth Abnormalities 2 | 66
Visual Impairment 2 | 167
Waldenstrons macroglobulinemia 2 | 742
Xerosis 2 | 74
gastric cancer 2 | 445
hepatocellular carcinoma 2 | 536
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,872
nasopharyngeal carcinoma 2 | 1,024
pancreatic cancer 2 | 2,322
pancreatic carcinoma 2 | 555
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,911
posterior fossa group B ependymoma 2 | 406
primitive neuroectodermal tumor 2 | 2,957

Tissue

Blood and immune system 16 | 16,909
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Cardiovascular System 15 | 15,192
Male tissues 15 | 17,142
Nervous System 15 | 16,725
Respiratory system 15 | 16,393

Target Family

Non-IDG 8 | 12,091
Enzyme 7 | 4,145
Transporter 1 | 473

Compartment GO Term

ERCC4-ERCC1 complex 16 | 16
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA cross-link repair 1A protein DCLRE1A Tbio Non-IDG -1.94675 90.4 92
Tyrosyl-DNA phosphodiesterase 1 TDP1 Tchem Enzyme -2.09041 139.4 210
Structure-specific endonuclease subunit SLX4 SLX4 Tbio Enzyme -1.68794 61.7 56
Uncharacterized protein C9orf84 C9orf84 Tdark Non-IDG 0.30 0.50 27
Mitochondrial ornithine transporter 1 SLC25A15 Tbio Transporter -2.21589 161.5 45
UV excision repair protein RAD23 homolog B RAD23B Tbio Non-IDG -1.99412 96.8 313
Crossover junction endonuclease MUS81 MUS81 Tbio Enzyme -2.06893 119.1 95
Flap endonuclease 1 FEN1 Tchem Enzyme -2.79171 617.0 406
DNA repair protein complementing XP-A cells XPA Tbio Non-IDG -2.87504 739.6 379
RecQ-mediated genome instability protein 1 RMI1 Tbio Non-IDG -1.59510 41.3 118