Development Level

Tbio 133 | 10,625
Tdark 8 | 7,003
Tchem 7 | 1,890
Tclin 1 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
embryonic lethality prior to t... 4 | 187
abnormal testis morphology 2 | 30
decreased body weight 2 | 174
decreased circulating HDL chol... 2 | 77
decreased circulating LDL chol... 2 | 37
decreased circulating choleste... 2 | 85
decreased circulating free fat... 2 | 39
decreased fasted circulating g... 2 | 49
decreased total body fat amoun... 2 | 186
embryonic lethality prior to o... 2 | 148
abnormal behavior 1 | 226
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal gait 1 | 51
abnormal heart morphology 1 | 51
abnormal kidney morphology 1 | 30
abnormal skin condition 1 | 6
absent vibrissae 1 | 14
decreased circulating alanine ... 1 | 53
decreased circulating alkaline... 1 | 41
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
embryonic growth retardation 1 | 28
enlarged epididymis 1 | 27
enlarged heart 1 | 111
enlarged heart atrium 1 | 2
increased blood urea nitrogen ... 1 | 44
increased circulating free fat... 1 | 17
increased mean corpuscular hem... 1 | 93
increased mean corpuscular vol... 1 | 91
increased or absent threshold ... 1 | 128
increased prepulse inhibition 1 | 21
limb grasping 1 | 35
shortened RR interval 1 | 19
small testis 1 | 37
thick ventricular wall 1 | 7

Disease

Cancer 84 | 2,346
diabetes mellitus 76 | 1,663
psoriasis 76 | 6,685
Ankylosing spondylitis 71 | 138
Hypersensitivity reaction type II disease 64 | 235
Juvenile rheumatoid arthritis 61 | 104
ovarian cancer 60 | 8,484
Acquired immunodeficiency syndrome 59 | 164
Arthritis 57 | 248
Uveitis 57 | 103
Behcet's disease 56 | 74
Rheumatoid Arthritis 54 | 1,160
Psoriatic arthritis 52 | 83
osteosarcoma 41 | 7,933
glioblastoma 38 | 5,572
Stevens-Johnson syndrome 37 | 78
Congenital adrenal hyperplasia 35 | 74
Retinal vasculitis 35 | 36
Takayasu's arteritis 35 | 52
Liver disease 29 | 219
Multiple Sclerosis 29 | 498
medulloblastoma, large-cell 28 | 6,234
lung cancer 26 | 4,466
Hepatitis B 24 | 103
Leprosy 24 | 77
Anemia 23 | 252
Hemochromatosis 23 | 55
Kidney disease 23 | 396
pancreatic ductal adenocarcinoma liver metastasis 23 | 1,795
Skin disease 22 | 65
atypical teratoid / rhabdoid tumor 22 | 4,369
Primary immunodeficiency disease 21 | 52
pilocytic astrocytoma 21 | 3,086
lung carcinoma 20 | 2,844
Multiple myeloma 19 | 1,327
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,956
invasive ductal carcinoma 18 | 2,950
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,289
lung adenocarcinoma 17 | 2,713
pancreatic cancer 17 | 2,300
Breast cancer 16 | 3,094
astrocytoma 16 | 1,493
intraductal papillary-mucinous carcinoma (IPMC) 16 | 2,988
breast carcinoma 15 | 1,614
dermatomyositis 15 | 933
juvenile dermatomyositis 15 | 1,189
pre-eclampsia 15 | 67
subependymal giant cell astrocytoma 15 | 2,287
Human immunodeficiency virus infectious disease 14 | 92
interstitial cystitis 14 | 2,299
non-small cell lung cancer 14 | 2,798
pediatric high grade glioma 14 | 2,712
group 4 medulloblastoma 13 | 1,875
posterior fossa group A ependymoma 13 | 1,511
malignant mesothelioma 12 | 3,162
cutaneous lupus erythematosus 11 | 1,056
ulcerative colitis 11 | 2,087
active Crohn's disease 10 | 918
acute quadriplegic myopathy 10 | 1,157
pancreatic carcinoma 10 | 567
primary Sjogren syndrome 10 | 789
adult high grade glioma 9 | 2,148
tuberculosis 9 | 1,557
Carcinoma 8 | 2,147
Duchenne muscular dystrophy 8 | 602
ependymoma 8 | 2,514
esophageal adenocarcinoma 8 | 737
oligodendroglioma 8 | 2,849
Waldenstrons macroglobulinemia 7 | 765
hepatocellular carcinoma 7 | 532
pituitary cancer 7 | 1,972
posterior fossa group B ependymoma 7 | 1,530
primitive neuroectodermal tumor 7 | 3,031
Asthma 6 | 349
Down syndrome 6 | 548
Pick disease 6 | 1,893
active ulcerative colitis 6 | 477
astrocytic glioma 6 | 2,241
cystic fibrosis 6 | 1,665
gastric carcinoma 6 | 832
inflammatory breast cancer 6 | 404
medulloblastoma 6 | 1,524
Becker muscular dystrophy 5 | 187
Congenital dyserythropoietic anemia 5 | 17
Endometriosis 5 | 535
IGA Glomerulonephritis 5 | 454
Liver carcinoma 5 | 217
Stomach Neoplasms 5 | 282
Vascular disease 5 | 281
adrenocortical carcinoma 5 | 1,427
group 3 medulloblastoma 5 | 2,254
limb girdle muscular dystrophy 2I 5 | 56
non primary Sjogren syndrome sicca 5 | 840
sarcoidosis 5 | 358
spina bifida 5 | 1,064
tuberculosis and treatment for 6 months 5 | 686
Prostatic Neoplasms 4 | 471
acute myeloid leukemia 4 | 780
primary pancreatic ductal adenocarcinoma 4 | 1,271
sonic hedgehog group medulloblastoma 4 | 1,482

Tissue

Blood and immune system 86 | 17,995
Cardiovascular System 86 | 17,958
Digestive Tract 86 | 18,473
Endocrine System 86 | 18,512
Female tissues 86 | 18,647
Liver and Pancreas 86 | 18,136
Male tissues 86 | 17,969
Nervous System 86 | 18,561
Respiratory system 86 | 17,484
Urinary Tract 86 | 18,444
Skin and soft tissues 79 | 18,115

Target Family

Non-IDG 139 | 11,971
Enzyme 6 | 4,146
Transcription Factor 3 | 1,400
Ion Channel 1 | 341

Compartment GO Term

ER to Golgi transport vesicle 149 | 149
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

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