Development Level

Tbio 72 | 11,178
Tdark 19 | 6,569
Tchem 4 | 1,885

IMPC Phenotype

preweaning lethality, complete... 12 | 979
preweaning lethality, incomple... 5 | 499
abnormal embryo size 2 | 220
abnormal lung morphology 2 | 26
abnormal seminal vesicle morph... 2 | 114
abnormal tail morphology 2 | 25
decreased total body fat amoun... 2 | 207
edema 2 | 59
embryonic growth retardation 2 | 106
hemorrhage 2 | 23
increased fasted circulating g... 2 | 76
long tibia 2 | 25
male infertility 2 | 123
abnormal coat appearance 1 | 31
abnormal ileum morphology 1 | 2
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal sleep behavior 1 | 70
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased B cell number 1 | 5
decreased body length 1 | 101
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating sodium l... 1 | 22
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased heart weight 1 | 62
increased lean body mass 1 | 172
microphthalmia 1 | 26
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
syndactyly 1 | 23

Disease

Carcinoma 65 | 11,192
ependymoma 51 | 4,559
ovarian cancer 43 | 8,297
osteosarcoma 42 | 7,766
atypical teratoid / rhabdoid tumor 36 | 4,971
medulloblastoma, large-cell 36 | 6,086
glioblastoma 32 | 5,635
psoriasis 30 | 6,514
Primary ciliary dyskinesia 29 | 75
Breast cancer 27 | 3,469
Kidney cancer 26 | 2,548
group 3 medulloblastoma 25 | 4,002
nasopharyngeal carcinoma 25 | 1,024
lung cancer 24 | 4,607
Situs Inversus 23 | 61
adult high grade glioma 23 | 3,701
primitive neuroectodermal tumor 22 | 2,957
Liver cancer 21 | 589
chronic rhinosinusitis 21 | 505
Ciliary Motility Disorders 19 | 38
Kartagener Syndrome 19 | 38
lung adenocarcinoma 18 | 2,627
malignant mesothelioma 17 | 3,135
Autosomal recessive predisposition 16 | 1,407
lung carcinoma 16 | 2,755
Pick disease 15 | 1,856
Ciliary Dyskinesia, Primary, 1 14 | 27
astrocytic glioma 14 | 2,530
oligodendroglioma 14 | 2,768
pancreatic cancer 14 | 2,322
Astrocytoma, Pilocytic 13 | 3,006
adrenocortical carcinoma 13 | 1,385
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,902
non-small cell lung cancer 13 | 2,799
Recurrent respiratory infections 12 | 138
Endometrial cancer 11 | 301
Male infertility 11 | 199
colon cancer 11 | 1,428
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,204
invasive ductal carcinoma 11 | 2,867
ductal carcinoma in situ 10 | 1,686
Bronchiectasis 9 | 63
Cancer 9 | 2,388
Melanoma 9 | 689
Multiple myeloma 9 | 1,296
Alzheimer's disease 8 | 640
Sinusitis 8 | 63
Situs ambiguus 8 | 22
breast carcinoma 8 | 1,589
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,872
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,911
subependymal giant cell astrocytoma 8 | 2,230
tuberculosis 8 | 1,963
Atopic dermatitis 7 | 915
Neurodegenerative disease 7 | 402
Polydactyly 7 | 106
Skin cancer 7 | 451
pediatric high grade glioma 7 | 1,035
Endometriosis 6 | 521
Lissencephaly 6 | 69
Microcephaly 6 | 166
Small head 6 | 366
astrocytoma 6 | 1,113
dermatomyositis 6 | 941
diabetes mellitus 6 | 1,683
group 4 medulloblastoma 6 | 1,806
pituitary cancer 6 | 1,915
progressive supranuclear palsy 6 | 656
ulcerative colitis 6 | 1,765
Asphyxiating thoracic dystrophy 5 | 44
Ciliopathy 5 | 71
DOID:2627 5 | 89
Intellectual disability 5 | 998
Paranasal Sinus Diseases 5 | 34
Recurrent sinus disease 5 | 22
Recurrent sinusitis 5 | 22
Right atrial isomerism 5 | 27
Short Rib-Polydactyly Syndrome 5 | 13
acute myeloid leukemia 5 | 760
cutaneous lupus erythematosus 5 | 1,016
cystic fibrosis 5 | 1,629
cystic fibrosis and chronic rhinosinusitis 5 | 211
gastric cancer 5 | 445
juvenile dermatomyositis 5 | 1,147
medulloblastoma 5 | 702
non-small cell lung carcinoma 5 | 302
Cerebellar Hypoplasia 4 | 61
Congenital Epicanthus 4 | 175
Decreased tendon reflex 4 | 121
Epilepsy 4 | 775
Hydrocephalus 4 | 148
Neuropathy 4 | 254
Rheumatoid arthritis 4 | 1,156
Schizophrenia 4 | 1,136
Seizures 4 | 584
acute quadriplegic myopathy 4 | 1,133
fibroadenoma 4 | 538
interstitial cystitis 4 | 2,237
posterior fossa group B ependymoma 4 | 406
spina bifida 4 | 1,053

Tissue

Endocrine System 95 | 18,159
Skin and soft tissues 94 | 17,230
Respiratory system 93 | 16,393
Digestive Tract 92 | 17,369
Female tissues 92 | 17,400
Male tissues 91 | 17,142
Nervous System 90 | 16,725
Urinary Tract 89 | 16,678
Blood and immune system 88 | 16,909
Liver and Pancreas 88 | 16,750
Cardiovascular System 81 | 15,192

Target Family

Non-IDG 90 | 12,091
Enzyme 5 | 4,145

Compartment GO Term

Dynein complex 95 | 95
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dynein assembly factor with WDR repeat domains 1 DAW1 Tdark Non-IDG -0.80163 6.92 13
Ras-related protein Rab-6A RAB6A Tbio Enzyme -2.09488 134.5 207
Dynein heavy chain 5, axonemal DNAH5 Tbio Non-IDG -1.46000 27.2 32
Dynein heavy chain 2, axonemal DNAH2 Tdark Non-IDG -0.65482 4.13 58
Dynein light chain roadblock-type 2 DYNLRB2 Tbio Non-IDG -0.65444 2.59 77
Dynein heavy chain 1, axonemal DNAH1 Tbio Non-IDG -1.30285 17.4 21
SNARE-associated protein Snapin SNAPIN Tbio Non-IDG -1.65821 50.9 69
Rab-interacting lysosomal protein RILP Tbio Non-IDG -0.98170 12.2 47
Cytoplasmic dynein 1 heavy chain 1 DYNC1H1 Tbio Non-IDG -1.80946 62.1 94
Thioredoxin domain-containing protein 3 NME8 Tbio Non-IDG -1.03981 11.2 79