Development Level

Tbio 18 | 11,445
Tdark 4 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal coat-hair pigmentatio... 1 | 64
cataract 1 | 92
decreased circulating LDL chol... 1 | 38
decreased total body fat amoun... 1 | 207
impaired righting response 1 | 26
increased lean body mass 1 | 172
persistence of hyaloid vascula... 1 | 33
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 14 | 11,493
ovarian cancer 13 | 8,520
Autosomal recessive predisposition 11 | 1,442
lung cancer 9 | 4,740
osteosarcoma 9 | 7,950
Cerebellar Ataxia 8 | 304
Muscle hypotonia 8 | 571
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
psoriasis 8 | 6,694
Acidosis, Lactic 7 | 97
Cognitive delay 7 | 608
Epilepsy 7 | 792
Global developmental delay 7 | 608
Lactic acidemia 7 | 95
Mental and motor retardation 7 | 608
glioblastoma 7 | 5,792
lung carcinoma 7 | 2,843
medulloblastoma, large-cell 7 | 6,241
Dull intelligence 6 | 645
Intellectual disability 6 | 1,016
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Seizures 6 | 596
astrocytic glioma 6 | 2,597
group 3 medulloblastoma 6 | 4,104
Hypoglycemia 5 | 152
Kidney cancer 5 | 2,613
Maple syrup urine disease 5 | 24
adult high grade glioma 5 | 3,801
atypical teratoid / rhabdoid tumor 5 | 5,112
interstitial cystitis 5 | 2,312
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
Dystonia 4 | 164
Dystonic disease 4 | 106
Feeding difficulties in infancy 4 | 175
Hallucinations 4 | 34
Hallucinations, Sensory 4 | 33
Ketonemia 4 | 11
Ketosis 4 | 11
Leigh disease 4 | 100
Lethargy 4 | 77
Metabolic acidosis 4 | 90
Muscle Hypertonia 4 | 88
Small head 4 | 374
Vomiting 4 | 116
ependymoma 4 | 4,679
primitive neuroectodermal tumor 4 | 3,035
Atopic dermatitis 3 | 952
Brain Edema 3 | 50
Cerebral Edema 3 | 30
Classic Maple Syrup Urine Disease 3 | 3
Comatose 3 | 56
Elevated plasma branched chain amino acids 3 | 3
Infantile onset 3 | 238
Intermediate Maple Syrup Urine Disease 3 | 4
Intermittent Maple Syrup Urine Disease 3 | 3
Lactic acidosis 3 | 51
Maple Syrup Urine Disease, Thiamine Responsive 3 | 3
Pancreatitis 3 | 123
Pick disease 3 | 1,894
Primary biliary cirrhosis 3 | 51
abnormal growth 3 | 26
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
medulloblastoma 3 | 720
Abnormal ocular motility 2 | 19
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Breast cancer 2 | 3,578
Crohn's disease 2 | 321
Delayed speech and language development 2 | 112
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Highly variable severity 2 | 157
Hypersensitivity reaction type II disease 2 | 253
Language Delay 2 | 112
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Multiple myeloma 2 | 1,332
Neurodegenerative disease 2 | 414
Neurogenic Muscular Atrophy 2 | 139
Phenotypic variability 2 | 150
Speech Delay 2 | 112
Speech impairment 2 | 112
Variable expressivity 2 | 157
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
gastric cancer 2 | 459
hereditary spastic paraplegia 2 | 318
muscle degeneration 2 | 139
non-small cell lung cancer 2 | 2,890
ulcerative colitis 2 | 1,819

Tissue

Blood and immune system 23 | 16,909
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Liver and Pancreas 23 | 16,750
Male tissues 23 | 17,142
Nervous System 23 | 16,725
Respiratory system 23 | 16,393
Skin and soft tissues 23 | 17,230
Urinary Tract 23 | 16,678

Target Family

Enzyme 14 | 4,145
Non-IDG 7 | 12,091
Kinase 1 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

Dihydrolipoyl dehydrogenase co... 23 | 23
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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