Development Level

Tbio 74 | 11,445
Tchem 20 | 1,598
Tclin 8 | 613
Tdark 2 | 6,588

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal behavior 6 | 298
preweaning lethality, incomple... 6 | 499
embryonic lethality prior to t... 5 | 278
increased bone mineral content 4 | 108
abnormal bone structure 3 | 187
abnormal retina morphology 3 | 71
decreased total body fat amoun... 3 | 207
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
increased circulating chloride... 3 | 41
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
abnormal sleep behavior 2 | 70
abnormal vertebrae morphology 2 | 18
decreased body weight 2 | 161
decreased bone mineral content 2 | 151
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
decreased mean corpuscular vol... 2 | 79
enlarged heart 2 | 210
increased circulating sodium l... 2 | 71
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
increased or absent threshold ... 2 | 101
increased startle reflex 2 | 112
thin ventricular wall 2 | 24
tremors 2 | 39
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal chorioallantoic fusio... 1 | 8
abnormal coat appearance 1 | 31
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal iris pigmentation 1 | 4
abnormal retinal inner nuclear... 1 | 8
abnormal retinal vasculature m... 1 | 27
abnormal rib morphology 1 | 10
cataract 1 | 92
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased IgG1 level 1 | 8
decreased IgG2b level 1 | 4
decreased T cell number 1 | 15
decreased cardiac output 1 | 3
decreased caudal vertebrae num... 1 | 53
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating total pr... 1 | 49
decreased exploration in new e... 1 | 11
decreased granulocyte number 1 | 6
decreased heart left ventricle... 1 | 28
decreased leukocyte cell numbe... 1 | 73
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased total retina thickne... 1 | 17
embryonic growth retardation 1 | 106
enlarged kidney 1 | 14
hypoactivity 1 | 132
increased IgG2b level 1 | 1
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total retina thickne... 1 | 4
pallor 1 | 34
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
premature death 1 | 5
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
short tibia 1 | 97
small superior vagus ganglion 1 | 74

Disease

Carcinoma 80 | 11,493
medulloblastoma, large-cell 72 | 6,241
glioblastoma 64 | 5,792
atypical teratoid / rhabdoid tumor 63 | 5,112
ependymoma 61 | 4,679
ovarian cancer 58 | 8,520
osteosarcoma 49 | 7,950
Astrocytoma, Pilocytic 48 | 3,081
adult high grade glioma 48 | 3,801
group 3 medulloblastoma 47 | 4,104
oligodendroglioma 46 | 2,850
psoriasis 43 | 6,694
primitive neuroectodermal tumor 40 | 3,035
astrocytic glioma 39 | 2,597
lung cancer 39 | 4,740
Schizophrenia 38 | 1,160
lung carcinoma 34 | 2,843
Breast cancer 30 | 3,578
Bipolar Disorder 29 | 666
Kidney cancer 29 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
malignant mesothelioma 26 | 3,232
Alzheimer's disease 25 | 658
subependymal giant cell astrocytoma 25 | 2,287
Pick disease 24 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
invasive ductal carcinoma 24 | 2,951
non-small cell lung cancer 24 | 2,890
Cancer 23 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
pancreatic cancer 23 | 2,398
Intellectual disability 22 | 1,016
pituitary cancer 22 | 1,972
Epilepsy 21 | 792
interstitial cystitis 19 | 2,312
Autistic Disorder 18 | 364
lung adenocarcinoma 18 | 2,716
Depressive disorder 17 | 409
Parkinson's disease 17 | 392
group 4 medulloblastoma 17 | 1,855
Toxic encephalopathy 16 | 141
ulcerative colitis 16 | 1,819
Cerebrovascular disease 14 | 238
Major Depressive Disorder 14 | 301
pediatric high grade glioma 14 | 1,064
Amyotrophic lateral sclerosis 13 | 451
breast carcinoma 13 | 1,638
cystic fibrosis 13 | 1,696
ductal carcinoma in situ 13 | 1,745
Melanoma 12 | 711
Mental Depression 12 | 333
Skin cancer 12 | 469
Unipolar Depression 12 | 250
spina bifida 12 | 1,074
Dementia 11 | 175
Neurodegenerative disease 11 | 414
Rheumatoid arthritis 11 | 1,191
Seizures 11 | 596
acute quadriplegic myopathy 11 | 1,158
adrenocortical carcinoma 11 | 1,428
diabetes mellitus 11 | 1,728
tuberculosis 11 | 2,010
Down syndrome 10 | 499
Liver cancer 10 | 604
astrocytoma 10 | 1,146
pancreatic carcinoma 10 | 562
Autosomal recessive predisposition 9 | 1,442
Fragile X syndrome 9 | 34
Mood Disorders 9 | 184
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
colon cancer 9 | 1,478
juvenile dermatomyositis 9 | 1,187
Alcoholic Intoxication, Chronic 8 | 289
Atopic dermatitis 8 | 952
Autism spectrum disorder 8 | 101
Brain Ischemia 8 | 110
Cocaine-Related Disorders 8 | 92
Duchenne muscular dystrophy 8 | 601
Dull intelligence 8 | 645
Huntington's disease 8 | 76
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
cutaneous lupus erythematosus 8 | 1,057
non primary Sjogren syndrome sicca 8 | 891
primary pancreatic ductal adenocarcinoma 8 | 1,109
Attention deficit hyperactivity disorder 7 | 278
Brain disease 7 | 96
Cognitive delay 7 | 608
Global developmental delay 7 | 608
Mental and motor retardation 7 | 608
Obesity 7 | 678
active Crohn's disease 7 | 922
gastric cancer 7 | 459
gastric carcinoma 7 | 807
hepatocellular carcinoma 7 | 547
Heart disease 6 | 306
Kidney disease 6 | 430
Multiple myeloma 6 | 1,332

Tissue

Endocrine System 100 | 18,159
Digestive Tract 99 | 17,369
Female tissues 98 | 17,400
Skin and soft tissues 98 | 17,230
Male tissues 97 | 17,142
Nervous System 97 | 16,725
Liver and Pancreas 96 | 16,750
Urinary Tract 96 | 16,678
Blood and immune system 94 | 16,909
Respiratory system 93 | 16,393
Cardiovascular System 84 | 15,192

Target Family

Non-IDG 58 | 12,091
Enzyme 20 | 4,145
Ion Channel 9 | 344
Kinase 7 | 634
GPCR 3 | 408
Transporter 3 | 473
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Dendritic spine 104 | 104
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Signal-induced proliferation-associated 1-like protein 1 SIPA1L1 Tbio Non-IDG -0.56258 5.05 40
Calbindin CALB1 Tbio Non-IDG -3.31956 2149.9 287
Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C Tbio Non-IDG -2.61667 619.4 0
Reelin RELN Tbio Non-IDG -2.78255 645.2 121
FERM, ARHGEF and pleckstrin domain-containing protein 1 FARP1 Tbio Non-IDG -1.56544 38.3 153
SLIT-ROBO Rho GTPase-activating protein 2B SRGAP2B Tdark Enzyme -1.09985 24.7 11
E3 ubiquitin-protein ligase NEURL1 NEURL1 Tbio Enzyme -1.09204 13.1 165
Lymphocyte transmembrane adapter 1 LAX1 Tbio Non-IDG -3.08498 1170.4 188
Regulator of G-protein signaling 14 RGS14 Tbio Non-IDG -1.61170 43.9 233
PDZ and LIM domain protein 4 PDLIM4 Tbio Non-IDG -2.02708 99.1 145