Development Level

Tbio 191 | 10,625
Tchem 63 | 1,890
Tclin 47 | 602
Tdark 27 | 7,003

Collection

Eligible Ion Channel Proteins 6 | 117
Eligible non-olfactory GPCR Proteins 2 | 145
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 14 | 633
preweaning lethality, incomple... 9 | 260
decreased total body fat amoun... 8 | 186
abnormal behavior 7 | 226
decreased lean body mass 7 | 195
abnormal bone structure 6 | 131
increased circulating sodium l... 6 | 71
increased lean body mass 6 | 107
decreased bone mineral content 5 | 157
decreased grip strength 5 | 123
embryonic lethality prior to t... 5 | 187
decreased circulating alanine ... 4 | 53
decreased circulating alkaline... 4 | 41
enlarged heart 4 | 111
increased or absent threshold ... 4 | 128
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 77
decreased circulating aspartat... 3 | 27
decreased circulating serum al... 3 | 79
embryonic lethality prior to o... 3 | 148
improved glucose tolerance 3 | 56
increased blood urea nitrogen ... 3 | 44
increased bone mineral content 3 | 92
increased circulating chloride... 3 | 43
increased heart weight 3 | 37
increased mean corpuscular vol... 3 | 91
increased startle reflex 3 | 38
tremors 3 | 34
abnormal QRS complex 2 | 25
abnormal behavioral response t... 2 | 52
abnormal coping response 2 | 12
abnormal embryo size 2 | 112
abnormal gait 2 | 51
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
abnormal tooth morphology 2 | 24
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased circulating total pr... 2 | 41
decreased effector memory CD8-... 2 | 24
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased total retina thickne... 2 | 20
edema 2 | 11
hemorrhage 2 | 12
hyperactivity 2 | 108
increased body weight 2 | 42
increased circulating alkaline... 2 | 119
increased circulating phosphat... 2 | 24
increased grip strength 2 | 83
increased mean corpuscular hem... 2 | 93
male infertility 2 | 62
prenatal lethality prior to he... 2 | 64
abnormal eye morphology 1 | 38
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal skin morphology 1 | 23
abnormal vertebrae morphology 1 | 14
absent teeth 1 | 4
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased basophil cell number 1 | 11
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
limb grasping 1 | 35
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
premature death 1 | 5
short tibia 1 | 82
sparse hair 1 | 6
thin ventricular wall 1 | 5
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

medulloblastoma, large-cell 199 | 6,234
glioblastoma 173 | 5,572
ovarian cancer 146 | 8,492
atypical teratoid / rhabdoid tumor 144 | 4,369
pilocytic astrocytoma 138 | 3,086
osteosarcoma 137 | 7,933
oligodendroglioma 132 | 2,849
psoriasis 130 | 6,685
primitive neuroectodermal tumor 114 | 3,031
pediatric high grade glioma 103 | 2,712
lung cancer 91 | 4,473
astrocytic glioma 87 | 2,241
Carcinoma 86 | 2,147
ependymoma 86 | 2,514
Schizophrenia 81 | 503
Alzheimer's disease 76 | 644
Cancer 74 | 2,346
lung carcinoma 72 | 2,844
Pick disease 70 | 1,893
malignant mesothelioma 70 | 3,163
Breast cancer 69 | 3,099
subependymal giant cell astrocytoma 69 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,988
adult high grade glioma 65 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 64 | 3,289
invasive ductal carcinoma 64 | 2,950
Epilepsy 61 | 346
medulloblastoma 61 | 1,524
pituitary cancer 59 | 1,972
posterior fossa group A ependymoma 56 | 1,511
non-small cell lung cancer 55 | 2,798
Parkinson's disease 54 | 364
astrocytoma 54 | 1,493
interstitial cystitis 49 | 2,299
group 3 medulloblastoma 47 | 2,254
lung adenocarcinoma 46 | 2,714
Neurodegenerative disease 45 | 383
Toxic encephalopathy 45 | 131
sonic hedgehog group medulloblastoma 45 | 1,482
diabetes mellitus 43 | 1,663
ulcerative colitis 43 | 2,087
colon cancer 42 | 1,475
pancreatic cancer 42 | 2,300
group 4 medulloblastoma 41 | 1,875
Intellectual disability 40 | 573
ductal carcinoma in situ 39 | 1,745
Autistic Disorder 38 | 320
cystic fibrosis 38 | 1,670
atypical teratoid/rhabdoid tumor 37 | 1,095
breast carcinoma 37 | 1,614
posterior fossa group B ependymoma 37 | 1,530
Obesity 35 | 616
Amyotrophic Lateral Sclerosis 34 | 432
Bipolar Disorder 33 | 266
Dementia 33 | 129
acute quadriplegic myopathy 32 | 1,157
Down syndrome 30 | 548
Seizures 30 | 95
Cocaine-Related Disorders 28 | 88
adrenocortical carcinoma 28 | 1,427
Cerebrovascular disease 27 | 231
tuberculosis 27 | 1,563
Alcohol dependence 26 | 107
Major Depressive Disorder 26 | 106
juvenile dermatomyositis 25 | 1,189
Pain agnosia 24 | 99
spina bifida 24 | 1,064
Huntington's disease 23 | 72
Atopic dermatitis 22 | 944
Multiple Sclerosis 21 | 498
cutaneous lupus erythematosus 21 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
Multiple myeloma 20 | 1,328
Attention deficit hyperactivity disorder 19 | 156
Migraine 19 | 79
dermatomyositis 19 | 967
gastric carcinoma 19 | 832
nasopharyngeal carcinoma 19 | 1,056
Duchenne muscular dystrophy 18 | 602
Hypertension 18 | 293
active Crohn's disease 18 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 499
Brain disease 17 | 84
Status Epilepticus 17 | 85
aldosterone-producing adenoma 17 | 664
pancreatic carcinoma 17 | 567
progressive supranuclear palsy 17 | 674
Heart disease 16 | 279
Hyperactive behavior 16 | 31
Neuropathy 16 | 210
Rheumatoid Arthritis 16 | 1,171
Substance abuse 16 | 55
non primary Sjogren syndrome sicca 16 | 840
primary pancreatic ductal adenocarcinoma 16 | 1,271
Amnestic disorder 15 | 37
Asthma 15 | 349
Hyperalgesia 15 | 71
Nerve Degeneration 15 | 73
Waldenstrons macroglobulinemia 15 | 765

Tissue

Female tissues 327 | 18,647
Digestive Tract 323 | 18,473
Endocrine System 323 | 18,512
Nervous System 323 | 18,561
Urinary Tract 323 | 18,444
Liver and Pancreas 321 | 18,136
Skin and soft tissues 317 | 18,115
Cardiovascular System 315 | 17,958
Male tissues 310 | 17,969
Blood and immune system 309 | 17,995
Respiratory system 305 | 17,484

Target Family

Non-IDG 173 | 11,969
Enzyme 49 | 4,146
Ion Channel 31 | 341
GPCR 26 | 408
Kinase 22 | 634
Transporter 10 | 473
oGPCR 10 | 421
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Dendrite 328 | 328
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synapsin-1 SYN1 Tbio Non-IDG -2.85684 687.9 716
Tubulin beta-3 chain TUBB3 Tclin Non-IDG -2.04546 78.8 485
Metabotropic glutamate receptor 7 GRM7 Tbio GPCR -2.23649 186.6 266
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.20483 1368.4 194
Zinc finger protein 385A ZNF385A Tbio Non-IDG 0.20 0.99 87
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 MAGI2 Tbio Enzyme -1.52265 31.6 171
Melanopsin OPN4 Tbio GPCR -2.73085 537.3 58
Potassium voltage-gated channel subfamily B member 1 KCNB1 Tclin Ion Channel -2.55260 357.6 349
Syntaxin-4 STX4 Tbio Non-IDG -1.93051 79.1 192
Dystrophin-related protein 2 DRP2 Tdark Non-IDG -0.65960 4.32 45