Development Level

Tbio 191 | 10,625
Tchem 63 | 1,890
Tclin 47 | 602
Tdark 27 | 7,003

Collection

Eligible Ion Channel Proteins 6 | 117
Eligible non-olfactory GPCR Proteins 2 | 143
Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 14 | 633
preweaning lethality, incomple... 9 | 260
decreased total body fat amoun... 8 | 186
abnormal behavior 7 | 226
decreased lean body mass 7 | 195
abnormal bone structure 6 | 131
increased circulating sodium l... 6 | 71
increased lean body mass 6 | 107
decreased bone mineral content 5 | 157
decreased grip strength 5 | 123
embryonic lethality prior to t... 5 | 187
decreased circulating alanine ... 4 | 53
decreased circulating alkaline... 4 | 41
enlarged heart 4 | 111
increased or absent threshold ... 4 | 128
decreased body weight 3 | 174
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 77
decreased circulating aspartat... 3 | 27
decreased circulating serum al... 3 | 79
embryonic lethality prior to o... 3 | 148
improved glucose tolerance 3 | 56
increased blood urea nitrogen ... 3 | 44
increased bone mineral content 3 | 92
increased circulating chloride... 3 | 43
increased heart weight 3 | 37
increased mean corpuscular vol... 3 | 91
increased startle reflex 3 | 38
tremors 3 | 34
abnormal QRS complex 2 | 25
abnormal behavioral response t... 2 | 52
abnormal coping response 2 | 12
abnormal embryo size 2 | 112
abnormal gait 2 | 51
abnormal retinal pigmentation 2 | 61
abnormal sleep behavior 2 | 63
abnormal tooth morphology 2 | 24
decreased circulating choleste... 2 | 85
decreased circulating glucose ... 2 | 121
decreased circulating total pr... 2 | 41
decreased effector memory CD8-... 2 | 24
decreased mean corpuscular vol... 2 | 50
decreased prepulse inhibition 2 | 52
decreased total retina thickne... 2 | 20
edema 2 | 11
hemorrhage 2 | 12
hyperactivity 2 | 108
increased body weight 2 | 42
increased circulating alkaline... 2 | 119
increased circulating phosphat... 2 | 24
increased grip strength 2 | 83
increased mean corpuscular hem... 2 | 93
male infertility 2 | 62
prenatal lethality prior to he... 2 | 64
abnormal eye morphology 1 | 38
abnormal kidney morphology 1 | 30
abnormal limb bud morphology 1 | 15
abnormal locomotor activation 1 | 26
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal retinal blood vessel ... 1 | 18
abnormal skin morphology 1 | 23
abnormal vertebrae morphology 1 | 14
absent teeth 1 | 4
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased basophil cell number 1 | 11
decreased caudal vertebrae num... 1 | 49
decreased circulating bilirubi... 1 | 14
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating sodium l... 1 | 18
decreased circulating triglyce... 1 | 83
decreased exploration in new e... 1 | 9
decreased heart weight 1 | 44
decreased hemoglobin content 1 | 53
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular hem... 1 | 34
decreased neutrophil cell numb... 1 | 37
decreased vertical activity 1 | 22
enlarged lymph nodes 1 | 27
hydrops fetalis 1 | 22
increased circulating HDL chol... 1 | 63
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 53
increased circulating creatini... 1 | 29
increased circulating iron lev... 1 | 25
increased circulating serum al... 1 | 25
increased circulating triglyce... 1 | 24
increased mean corpuscular hem... 1 | 25
increased rib number 1 | 41
limb grasping 1 | 35
persistence of hyaloid vascula... 1 | 22
polycystic kidney 1 | 9
premature death 1 | 5
short tibia 1 | 82
sparse hair 1 | 6
thin ventricular wall 1 | 5
thrombocytopenia 1 | 46
thrombocytosis 1 | 23

Disease

medulloblastoma, large-cell 199 | 6,234
glioblastoma 173 | 5,572
ovarian cancer 146 | 8,484
atypical teratoid / rhabdoid tumor 144 | 4,369
pilocytic astrocytoma 138 | 3,086
osteosarcoma 137 | 7,933
oligodendroglioma 132 | 2,849
psoriasis 130 | 6,685
primitive neuroectodermal tumor 114 | 3,031
pediatric high grade glioma 103 | 2,712
lung cancer 91 | 4,466
astrocytic glioma 87 | 2,241
Carcinoma 86 | 2,147
ependymoma 86 | 2,514
Schizophrenia 81 | 501
Alzheimer's disease 76 | 644
Cancer 74 | 2,346
lung carcinoma 72 | 2,844
Pick disease 70 | 1,893
malignant mesothelioma 70 | 3,162
Breast cancer 69 | 3,094
subependymal giant cell astrocytoma 69 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 66 | 2,988
adult high grade glioma 65 | 2,148
intraductal papillary-mucinous adenoma (IPMA) 65 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 64 | 3,289
invasive ductal carcinoma 64 | 2,950
Epilepsy 61 | 346
medulloblastoma 61 | 1,524
pituitary cancer 59 | 1,972
posterior fossa group A ependymoma 56 | 1,511
non-small cell lung cancer 55 | 2,798
Parkinson's disease 54 | 364
astrocytoma 54 | 1,493
interstitial cystitis 49 | 2,299
group 3 medulloblastoma 47 | 2,254
lung adenocarcinoma 46 | 2,713
Neurodegenerative disease 45 | 383
Toxic encephalopathy 45 | 131
sonic hedgehog group medulloblastoma 45 | 1,482
diabetes mellitus 43 | 1,663
ulcerative colitis 43 | 2,087
colon cancer 42 | 1,475
pancreatic cancer 42 | 2,300
group 4 medulloblastoma 41 | 1,875
Intellectual disability 40 | 573
ductal carcinoma in situ 39 | 1,745
Autistic Disorder 38 | 320
atypical teratoid/rhabdoid tumor 37 | 1,095
breast carcinoma 37 | 1,614
cystic fibrosis 37 | 1,665
posterior fossa group B ependymoma 37 | 1,530
Obesity 35 | 616
Amyotrophic Lateral Sclerosis 34 | 431
Bipolar Disorder 33 | 266
Dementia 33 | 129
acute quadriplegic myopathy 32 | 1,157
Down syndrome 30 | 548
Seizures 30 | 95
Cocaine-Related Disorders 28 | 88
adrenocortical carcinoma 28 | 1,427
Cerebrovascular disease 27 | 231
Alcohol dependence 26 | 107
Major Depressive Disorder 26 | 106
tuberculosis 26 | 1,557
juvenile dermatomyositis 25 | 1,189
Pain agnosia 24 | 99
spina bifida 24 | 1,064
Huntington's disease 23 | 72
Atopic dermatitis 22 | 944
Multiple Sclerosis 21 | 498
cutaneous lupus erythematosus 21 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,795
Multiple myeloma 20 | 1,327
Attention deficit hyperactivity disorder 19 | 156
Migraine 19 | 79
dermatomyositis 19 | 933
gastric carcinoma 19 | 832
nasopharyngeal carcinoma 19 | 1,056
Duchenne muscular dystrophy 18 | 602
Hypertension 18 | 287
active Crohn's disease 18 | 918
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 499
Brain disease 17 | 83
Status Epilepticus 17 | 85
aldosterone-producing adenoma 17 | 664
pancreatic carcinoma 17 | 567
progressive supranuclear palsy 17 | 674
Heart disease 16 | 279
Hyperactive behavior 16 | 31
Neuropathy 16 | 210
Rheumatoid Arthritis 16 | 1,160
Substance abuse 16 | 55
non primary Sjogren syndrome sicca 16 | 840
primary pancreatic ductal adenocarcinoma 16 | 1,271
Amnestic disorder 15 | 37
Asthma 15 | 349
Hyperalgesia 15 | 71
Nerve Degeneration 15 | 73
Waldenstrons macroglobulinemia 15 | 765

Tissue

Female tissues 327 | 18,647
Digestive Tract 323 | 18,473
Endocrine System 323 | 18,512
Nervous System 323 | 18,561
Urinary Tract 323 | 18,444
Liver and Pancreas 321 | 18,136
Skin and soft tissues 317 | 18,115
Cardiovascular System 315 | 17,958
Male tissues 310 | 17,969
Blood and immune system 309 | 17,995
Respiratory system 305 | 17,484

Target Family

Non-IDG 173 | 11,971
Enzyme 49 | 4,146
Ion Channel 31 | 341
GPCR 26 | 406
Kinase 22 | 634
Transporter 10 | 473
oGPCR 10 | 421
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 1 | 48

Compartment GO Term

Dendrite 328 | 328
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
D(2) dopamine receptor DRD2 Tclin GPCR -3.24474 1775.2 248
Apolipoprotein E APOE Tbio Non-IDG -4.17470 15380.4 788
Protein Smaug homolog 1 SAMD4A Tbio Non-IDG 16.8 58
Sodium/calcium exchanger 2 SLC8A2 Tbio Transporter -1.56223 31.9 51
Cytoplasmic polyadenylation element-binding protein 1 CPEB1 Tbio Non-IDG -2.20580 171.1 185
Pro-neuropeptide Y NPY Tbio Non-IDG -3.81741 7285.3 401
Striatin STRN Tbio Non-IDG -1.63637 51.0 118
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.29395 203.8 55
Cytoplasmic polyadenylation element-binding protein 3 CPEB3 Tbio Non-IDG -1.28920 20.4 75
Ferritin heavy chain FTH1 Tbio Non-IDG -2.95630 924.5 435