Development Level

Tbio 18 | 11,445
Tchem 7 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal eating behavior 1 | 1
abnormal forced expiratory flo... 1 | 1
abnormal kidney morphology 1 | 65
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
abnormal whole-body plethysmog... 1 | 4
altered righting response 1 | 1
decreased body temperature 1 | 2
decreased body weight 1 | 161
decreased circulating insulin ... 1 | 76
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased tidal volume 1 | 1
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged kidney 1 | 14
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating iron lev... 1 | 30
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
male infertility 1 | 123

Disease

Carcinoma 17 | 11,493
osteosarcoma 13 | 7,950
psoriasis 12 | 6,694
glioblastoma 11 | 5,792
lung cancer 11 | 4,740
Kidney cancer 10 | 2,613
ependymoma 10 | 4,679
group 3 medulloblastoma 10 | 4,104
medulloblastoma, large-cell 10 | 6,241
Breast cancer 9 | 3,578
Cancer 9 | 2,499
lung carcinoma 8 | 2,843
Breast Neoplasms 7 | 445
Mammary Neoplasms 7 | 425
Schizophrenia 7 | 1,160
ovarian cancer 7 | 8,520
Astrocytoma, Pilocytic 6 | 3,081
astrocytic glioma 6 | 2,597
malignant mesothelioma 6 | 3,232
oligodendroglioma 6 | 2,850
primitive neuroectodermal tumor 6 | 3,035
Bipolar Disorder 5 | 666
Carcinoma, Pancreatic Ductal 5 | 20
Liver cancer 5 | 604
adult high grade glioma 5 | 3,801
astrocytoma 5 | 1,146
atypical teratoid / rhabdoid tumor 5 | 5,112
interstitial cystitis 5 | 2,312
non-small cell lung cancer 5 | 2,890
pancreatic cancer 5 | 2,398
ulcerative colitis 5 | 1,819
Alagille syndrome 4 | 15
Alzheimer's disease 4 | 658
Cadasil 4 | 10
Carcinoma, Squamous Cell 4 | 110
Osteoporosis 4 | 363
Pain agnosia 4 | 104
Skin Neoplasms 4 | 69
cystic fibrosis 4 | 1,696
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
pediatric high grade glioma 4 | 1,064
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Acquired scoliosis 3 | 281
Autosomal recessive predisposition 3 | 1,442
Brachydactyly 3 | 156
Cerebrovascular disease 3 | 238
Cryptorchidism 3 | 296
Curvature of spine 3 | 282
Esophageal Squamous Cell Carcinoma 3 | 77
Failure to gain weight 3 | 365
Hypertension 3 | 396
Long narrow head 3 | 75
Lung Neoplasms 3 | 232
Narrow cranium shape 3 | 75
Narrow head shape 3 | 75
Narrow skull shape 3 | 75
Orbital separation excessive 3 | 244
Pediatric failure to thrive 3 | 365
Rheumatoid arthritis 3 | 1,191
Shipyard eye 3 | 15
Short distal phalanges 3 | 50
Short neck 3 | 140
Short stature 3 | 531
Skin cancer 3 | 469
Spondylocostal dysostosis 3 | 12
Squamous cell carcinoma of esophagus 3 | 77
Turridolichocephaly 3 | 75
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
pituitary cancer 3 | 1,972
Adenoid Cystic Carcinoma 2 | 99
Byzanthine arch palate 2 | 194
Cholestasis 2 | 155
Colonic Neoplasms 2 | 142
Depressive disorder 2 | 409
Epilepsy 2 | 792
Kidney disease 2 | 430
Long philtrum 2 | 137
Major Depressive Disorder 2 | 301
Melanoma 2 | 711
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Neuroblastoma 2 | 80
Strabismus 2 | 270
Thin lips 2 | 49
Umbilical hernia 2 | 93
Unipolar Depression 2 | 250
active Crohn's disease 2 | 922
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
colon cancer 2 | 1,478
fibroadenoma 2 | 559
glioblastoma multiforme 2 | 142
medulloblastoma 2 | 720

Tissue

Blood and immune system 25 | 16,909
Cardiovascular System 25 | 15,192
Digestive Tract 25 | 17,369
Endocrine System 25 | 18,159
Female tissues 25 | 17,400
Liver and Pancreas 25 | 16,750
Male tissues 25 | 17,142
Respiratory system 25 | 16,393
Skin and soft tissues 25 | 17,230
Urinary Tract 25 | 16,678
Nervous System 24 | 16,725

Target Family

Non-IDG 13 | 12,091
Enzyme 9 | 4,145
Transcription Factor 2 | 1,400
Ion Channel 1 | 344

Compartment GO Term

Delta1 complex 25 | 25
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 PLCD1 Tchem Enzyme -2.17969 140.9 120
Transcription factor HES-5 HES5 Tbio Transcription Factor -2.08501 97.6 139
Gamma-secretase subunit PEN-2 PSENEN Tchem Enzyme -2.84761 677.3 204
Protocadherin-1 PCDH1 Tbio Non-IDG -1.32663 20.7 228
Serrate RNA effector molecule homolog SRRT Tbio Non-IDG -2.09395 108.5 108
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 PLCB2 Tbio Enzyme -2.14048 137.8 104
Beta-1,3-N-acetylglucosaminyltransferase manic fringe MFNG Tbio Enzyme -0.83827 6.67 114
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe LFNG Tbio Enzyme -1.50535 29.8 220
Transcription cofactor HES-6 HES6 Tbio Transcription Factor -1.72013 55.3 218
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 PLCD3 Tbio Enzyme -1.21205 17.5 66