Development Level

Tbio 113 | 11,651
Tdark 14 | 6,593
Tchem 10 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 27 | 979
embryonic lethality prior to o... 12 | 239
embryonic lethality prior to t... 8 | 278
abnormal embryo size 3 | 220
abnormal behavior 2 | 298
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
decreased red blood cell distr... 2 | 41
embryonic growth retardation 2 | 106
increased anti-nuclear antigen... 2 | 19
increased circulating magnesiu... 2 | 10
increased circulating potassiu... 2 | 29
increased lean body mass 2 | 172
increased mean corpuscular vol... 2 | 92
prenatal lethality prior to he... 2 | 87
abnormal chorioallantoic fusio... 1 | 8
abnormal cornea morphology 1 | 31
abnormal embryo turning 1 | 31
abnormal hair growth 1 | 10
abnormal neural tube closure 1 | 46
abnormal posture 1 | 2
abnormal seminal vesicle morph... 1 | 114
abnormal sensory capabilities-... 1 | 8
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
decreased KLRG1+ CD4 alpha bet... 1 | 5
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
enlarged lymph nodes 1 | 37
enlarged urinary bladder 1 | 8
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased effector memory CD4-... 1 | 1
increased erythrocyte cell num... 1 | 39
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
short tibia 1 | 97
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 81 | 11,493
ovarian cancer 71 | 8,520
osteosarcoma 60 | 7,950
lung cancer 43 | 4,740
psoriasis 31 | 6,694
group 3 medulloblastoma 28 | 4,104
Kidney cancer 26 | 2,613
glioblastoma 26 | 5,792
medulloblastoma, large-cell 26 | 6,241
malignant mesothelioma 24 | 3,232
Breast cancer 21 | 3,578
Multiple myeloma 21 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
atypical teratoid / rhabdoid tumor 17 | 5,112
Cancer 16 | 2,499
Cockayne syndrome 16 | 60
ependymoma 16 | 4,679
Intellectual disability 14 | 1,016
oligodendroglioma 14 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Autosomal recessive predisposition 12 | 1,442
Photosensitive trichothiodystrophy 12 | 30
astrocytic glioma 12 | 2,597
diabetes mellitus 12 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
primitive neuroectodermal tumor 12 | 3,035
tuberculosis 12 | 2,010
Pick disease 11 | 1,894
Xeroderma pigmentosum group B 11 | 20
group 4 medulloblastoma 11 | 1,855
invasive ductal carcinoma 11 | 2,951
non-small cell lung cancer 11 | 2,890
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Waldenstrons macroglobulinemia 10 | 765
adult high grade glioma 10 | 3,801
Dull intelligence 9 | 645
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Poor school performance 9 | 645
lung adenocarcinoma 9 | 2,716
pediatric high grade glioma 9 | 1,064
Cerebellar Ataxia 8 | 304
Muscle Spasticity 8 | 195
acute myeloid leukemia 8 | 783
astrocytoma 8 | 1,146
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
pancreatic cancer 8 | 2,398
Hypoplastic mandible condyle 7 | 275
Mandibular hypoplasia 7 | 275
Micrognathism 7 | 275
Short stature 7 | 531
lung carcinoma 7 | 2,843
pituitary cancer 7 | 1,972
Astrocytoma, Pilocytic 6 | 3,081
Cryptorchidism 6 | 296
Small head 6 | 374
Strabismus 6 | 270
Xeroderma pigmentosum 6 | 43
Xeroderma pigmentosum group D 6 | 33
aldosterone-producing adenoma 6 | 665
cystic fibrosis 6 | 1,696
dermatomyositis 6 | 966
ductal carcinoma in situ 6 | 1,745
hepatocellular carcinoma 6 | 547
non primary Sjogren syndrome sicca 6 | 891
sonic hedgehog group medulloblastoma 6 | 467
subependymal giant cell astrocytoma 6 | 2,287
Atrophy of cerebellum 5 | 103
Cerebellar Dysmetria 5 | 56
Cerebellar degeneration 5 | 103
Dysarthria 5 | 192
Epidermodysplasia verruciformis 5 | 21
Epilepsy 5 | 792
Hereditary spherocytosis type 5 5 | 12
Hyperreflexia 5 | 209
Impaired cognition 5 | 96
Infratentorial atrophy 5 | 103
Liver cancer 5 | 604
Low Vision 5 | 174
Melanoma 5 | 711
Mental impairment 5 | 95
Seizures 5 | 596
Sensorineural Hearing Loss (disorder) 5 | 284
Spinocerebellar ataxia type 7 5 | 13
Visual Impairment 5 | 174
acute quadriplegic myopathy 5 | 1,158
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
pancreatic carcinoma 5 | 562
Asthma 4 | 385
Intrauterine retardation 4 | 176
Lens Opacities 4 | 231
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
Uranostaphyloschisis 4 | 167
gastric carcinoma 4 | 807
primary pancreatic ductal adenocarcinoma 4 | 1,109

Tissue

Endocrine System 136 | 18,159
Blood and immune system 135 | 16,909
Digestive Tract 135 | 17,369
Female tissues 135 | 17,400
Liver and Pancreas 135 | 16,750
Male tissues 135 | 17,142
Respiratory system 135 | 16,393
Skin and soft tissues 135 | 17,230
Urinary Tract 135 | 16,678
Nervous System 134 | 16,725
Cardiovascular System 133 | 15,192

Target Family

Enzyme 68 | 4,145
Non-IDG 63 | 12,091
Epigenetic 4 | 242
Kinase 3 | 634

Compartment GO Term

DNA-directed RNA polymerase co... 138 | 138
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.65323 46.0 231
DNA-directed RNA polymerase III subunit RPC3 POLR3C Tbio Enzyme -0.84213 6.37 136
Mediator of RNA polymerase II transcription subunit 18 MED18 Tbio Enzyme -1.00423 10.4 161
DNA-directed RNA polymerase I subunit RPA43 TWISTNB Tdark Enzyme -0.05799 1.13 69
Integrator complex subunit 6 INTS6 Tbio Non-IDG -2.07240 118.9 80
Transcription initiation factor IIB GTF2B Tbio Non-IDG -2.63302 410.1 286
Mediator of RNA polymerase II transcription subunit 10 MED10 Tdark Enzyme -1.38171 24.0 16
DNA-directed RNA polymerase III subunit RPC5 POLR3E Tbio Enzyme -2.17742 145.9 76
RNA polymerase-associated protein LEO1 LEO1 Tbio Enzyme -2.07251 114.4 293
Integrator complex subunit 10 INTS10 Tdark Non-IDG -0.67290 3.96 116