Development Level

Tbio 14 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

decreased circulating sodium l... 1 | 22
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating free fat... 1 | 20
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 8 | 8,520
lung cancer 6 | 4,740
Multiple myeloma 5 | 1,332
osteosarcoma 5 | 7,950
Carcinoma 4 | 11,493
Hereditary spherocytosis type 5 4 | 12
diabetes mellitus 4 | 1,728
group 3 medulloblastoma 3 | 4,104
psoriasis 3 | 6,694
Cockayne syndrome 2 | 60
Congenital myasthenic syndrome 5 2 | 11
Kidney cancer 2 | 2,613
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
glioblastoma 2 | 5,792
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
Amyotrophic lateral sclerosis 1 | 451
Anxiety 1 | 136
Anxiety disease 1 | 113
Atherosclerosis 1 | 291
Breast cancer 1 | 3,578
Cancer 1 | 2,499
Chikungunya 1 | 16
Ciliary Dyskinesia, Primary, 1 1 | 27
Dental caries 1 | 164
Depressive disorder 1 | 409
Diabetes Mellitus, Experimental 1 | 108
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Dyspnea 1 | 76
Ebola hemorrhagic fever 1 | 13
Endometriosis of ovary 1 | 5
Eumycotic mycetoma 1 | 3
Fatigable weakness of respiratory muscles 1 | 28
Fatigable weakness of swallowing muscles 1 | 28
Fatigue 1 | 182
Fatty liver disease 1 | 103
Fusariosis 1 | 6
Generalized muscle weakness 1 | 57
Heart failure 1 | 162
Huntington's disease 1 | 76
Hyperglycemia 1 | 137
La Crosse encephalitis 1 | 5
Lymphoid leukemia 1 | 160
Malaria 1 | 160
Megaloblastic anemia 1 | 18
Microsporidiosis 1 | 13
Mood swings 1 | 77
Motor neuron disease 1 | 49
Muscle Cramp 1 | 55
Muscle Spasticity 1 | 195
Myocardial Infarction 1 | 151
Neoplasms, Experimental 1 | 40
Nerve Degeneration 1 | 121
Neuro-degenerative disease 1 | 43
Neurodegeneration with brain iron accumulation 4 1 | 6
Neurodegenerative Disorders 1 | 79
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Ovarian Neoplasms 1 | 102
Pain 1 | 103
Paralysed 1 | 42
Parkinson's disease 1 | 392
Photosensitive trichothiodystrophy 1 | 30
Respiratory Failure 1 | 104
Schizophrenia 1 | 1,160
Skeletal muscle atrophy 1 | 139
Subcutaneous mycosis 1 | 2
Tetanus neonatorum 1 | 6
Tinea pedis 1 | 29
Xeroderma pigmentosum group B 1 | 20
Xerostomia 1 | 42
adult high grade glioma 1 | 3,801
aldosterone-producing adenoma 1 | 665
astrocytic glioma 1 | 2,597
colon cancer 1 | 1,478
dermatomyositis 1 | 966
ductal carcinoma in situ 1 | 1,745
gastric carcinoma 1 | 807
hepatocellular carcinoma 1 | 547
interstitial lung disease 1 | 298
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
invasive ductal carcinoma 1 | 2,951
muscle degeneration 1 | 139
nephrosclerosis 1 | 333
ovarian neoplasm 1 | 99
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
pediatric high grade glioma 1 | 1,064
pituitary cancer 1 | 1,972
posterior fossa group B ependymoma 1 | 416
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Enzyme 15 | 4,145
Non-IDG 1 | 12,091

Compartment GO Term

DNA-directed RNA polymerase II... 16 | 16
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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