Development Level

Tbio 9 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to o... 2 | 239
abnormal behavior 1 | 298
abnormal posture 1 | 2
decreased circulating sodium l... 1 | 22
embryonic lethality prior to t... 1 | 278
increased circulating free fat... 1 | 20

Disease

ovarian cancer 7 | 8,520
Multiple myeloma 4 | 1,332
lung cancer 4 | 4,740
Carcinoma 3 | 11,493
Hereditary spherocytosis type 5 3 | 12
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
primitive neuroectodermal tumor 3 | 3,035
Cleft Palate 2 | 271
Congenital small ears 2 | 48
Decreased projection of maxilla 2 | 66
Deficiency of upper jaw bones 2 | 66
Downward slant of palpebral fissure 2 | 158
Hypoplasia of the maxilla 2 | 66
Hypoplastic mandible condyle 2 | 275
Hypotrophic maxilla 2 | 66
Kidney cancer 2 | 2,613
Mandibular hypoplasia 2 | 275
Maxillary retrognathia 2 | 66
Micrognathism 2 | 275
Retrusion of upper jaw bones 2 | 66
Treacher Collins syndrome 2 | 27
Uranostaphyloschisis 2 | 167
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
non-small cell lung cancer 2 | 2,890
pediatric high grade glioma 2 | 1,064
psoriasis 2 | 6,694
Abnormal skeletal development 1 | 60
Abnormality of bone mineral density 1 | 5
Absent eyelashes 1 | 16
Acrocephalosyndactylia 1 | 17
Acrofacial dysostosis 1 | 8
Agenesis of teeth 1 | 21
Aplasia of eyelashes 1 | 16
Broad flat nasal bridge 1 | 236
CNS hypomyelination 1 | 17
Choanal Atresia 1 | 42
Ciliary Dyskinesia, Primary, 1 1 | 27
Coloboma of eyelid 1 | 15
Conductive hearing loss 1 | 123
Convex nasal bridge 1 | 57
Decreased projection of midface 1 | 105
Depressed cheekbone 1 | 22
Failure of development of eyelashes 1 | 16
Flattening of the zygomatic bone 1 | 22
Frontal bossing 1 | 157
Hypodontia 1 | 81
Hypomyelination 1 | 17
Hypomyelination-hypogonadotropic-hypogonadism-hypodontia syndrome 1 | 3
Hypoplasia of corpus callosum 1 | 90
Hypoplasia of the zygomatic bone 1 | 22
Hypotrophic cheekbone 1 | 22
Hypotrophic malar bone 1 | 129
Hypotrophic midface 1 | 105
Kidney hypertrophy 1 | 4
Large auricle 1 | 87
Large dysplastic ears 1 | 87
Large pinnae 1 | 87
Large prominent ears 1 | 87
Large protruding ears 1 | 87
Large, floppy ears 1 | 87
Leukodystrophy 1 | 55
Leukodystrophy, Hypomyelinating, with Hypodontia and Hypogonadotropic Hypogonadism 1 | 3
Low Vision 1 | 174
Macrotia 1 | 87
Malar flattening 1 | 129
Malformed pinnae 1 | 37
Midface retrusion 1 | 105
Narrow internal auditory canal 1 | 8
Nasal bridge wide 1 | 236
Neoplasms, Experimental 1 | 40
Open Bite 1 | 21
Osteochondrodysplasias 1 | 72
Primary hypogonadism 1 | 37
Prominent nasal bridge 1 | 57
Reduced number of teeth 1 | 21
Retinitis pigmentosa 12 1 | 9
Retrognathia 1 | 54
Short palpebral fissure 1 | 38
Small cheekbone 1 | 22
Small midface 1 | 105
Stomach Neoplasms 1 | 300
Strabismus 1 | 270
Tremor 1 | 113
Visual Impairment 1 | 174
acute quadriplegic myopathy 1 | 1,158
astrocytoma 1 | 1,146
atypical teratoid/rhabdoid tumor 1 | 357
colon cancer 1 | 1,478
hepatocellular carcinoma 1 | 547
lung adenocarcinoma 1 | 2,716
nasopharyngeal carcinoma 1 | 1,058
pancreatic carcinoma 1 | 562
posterior fossa group A ependymoma 1 | 468

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 11 | 4,145

Compartment GO Term

DNA-directed RNA polymerase I ... 11 | 11
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

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