Development Level

Tbio 10 | 11,445
Tchem 10 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal retinal inner nuclear... 1 | 8
abnormal spinal cord morpholog... 1 | 9
decreased circulating glucose ... 1 | 126
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
increased circulating sodium l... 1 | 71
preweaning lethality, complete... 1 | 979

Disease

Cancer 18 | 2,499
ovarian cancer 17 | 8,520
Carcinoma 16 | 11,493
osteosarcoma 15 | 7,950
lung cancer 14 | 4,740
Breast cancer 13 | 3,578
Nijmegen breakage syndrome 13 | 24
malignant mesothelioma 12 | 3,232
Ataxia telangiectasia 11 | 34
glioblastoma 11 | 5,792
group 3 medulloblastoma 11 | 4,104
medulloblastoma, large-cell 11 | 6,241
Breast Neoplasms 9 | 445
Kidney cancer 9 | 2,613
Mammary Neoplasms 9 | 425
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
primitive neuroectodermal tumor 9 | 3,035
psoriasis 9 | 6,694
Prostatic Neoplasms 8 | 495
atypical teratoid / rhabdoid tumor 8 | 5,112
non-small cell lung cancer 8 | 2,890
Chromosome Breakage 7 | 36
Schizophrenia 7 | 1,160
Werner syndrome 7 | 29
Xeroderma pigmentosum 7 | 43
breast carcinoma 7 | 1,638
Endometrial cancer 6 | 311
Intellectual disability 6 | 1,016
Severe combined immunodeficiency 6 | 51
Short stature 6 | 531
Small head 6 | 374
colon cancer 6 | 1,478
ependymoma 6 | 4,679
oligodendroglioma 6 | 2,850
Anemia 5 | 365
Autosomal recessive predisposition 5 | 1,442
DNA ligase IV deficiency 5 | 7
Dull intelligence 5 | 645
Fanconi anemia 5 | 56
Hereditary Breast and Ovarian Cancer Syndrome 5 | 14
Increased chromosomal breakage 5 | 27
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Microcephaly 5 | 166
Pancreatic Neoplasm 5 | 85
Pick disease 5 | 1,894
Poor school performance 5 | 645
Seckel syndrome 5 | 34
acute quadriplegic myopathy 5 | 1,158
adult high grade glioma 5 | 3,801
astrocytic glioma 5 | 2,597
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
lung adenocarcinoma 5 | 2,716
Adenoid Cystic Carcinoma 4 | 99
Carcinoma, Adenoid Cystic 4 | 99
Cognitive delay 4 | 608
Glioma 4 | 74
Global developmental delay 4 | 608
Li-Fraumeni syndrome 4 | 13
Liver cancer 4 | 604
Lymphoma 4 | 81
Malignant neoplasm of breast 4 | 15
Melanoma 4 | 711
Mental and motor retardation 4 | 608
Pancreatic Neoplasms 4 | 85
Waldenstrons macroglobulinemia 4 | 765
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
Acquired scoliosis 3 | 281
Acute blood cancer 3 | 6
Acute leukemia 3 | 15
Alopecia 3 | 115
Colorectal Neoplasms 3 | 243
Curvature of spine 3 | 282
DOID:2627 3 | 94
Endometriosis 3 | 540
Epilepsy 3 | 792
Hypoplastic mandible condyle 3 | 275
Intrauterine retardation 3 | 176
Leukopenia 3 | 72
Lung Neoplasms 3 | 232
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Multiple myeloma 3 | 1,332
Neurodegenerative disease 3 | 414
Pancytopenia 3 | 45
Prostate cancer 3 | 175
Seizures 3 | 596
Sloping forehead 3 | 46
Splenomegaly 3 | 190
Squamous cell carcinoma 3 | 129
Stomach Neoplasms 3 | 300
Thrombocytopenia 3 | 197
progressive supranuclear palsy 3 | 676
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819

Tissue

Blood and immune system 21 | 16,909
Cardiovascular System 21 | 15,192
Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678

Target Family

Non-IDG 11 | 12,091
Kinase 6 | 634
Enzyme 3 | 4,145
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Compartment GO Term

DNA-dependent protein kinase c... 22 | 22
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase SMG1 SMG1 Tchem Kinase -1.61615 60.9 195
Serine/threonine-protein kinase ATR ATR Tchem Kinase -2.80362 549.6 376
Methylated-DNA--protein-cysteine methyltransferase MGMT Tchem Enzyme -3.13356 1426.9 560
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
Putative uncharacterized SMG1-like protein N/A Tdark Non-IDG -1.61615 60.9 0
DNA ligase 4 LIG4 Tbio Enzyme -2.14909 140.9 204
Serine/threonine-protein kinase Chk2 CHEK2 Tchem Kinase -3.00304 978.7 1374
Serine/threonine-protein kinase Chk1 CHEK1 Tchem Kinase -3.04423 1089.6 1375
Non-homologous end-joining factor 1 NHEJ1 Tbio Non-IDG -1.93558 91.5 270