Development Level

Tbio 90 | 10,625
Tchem 22 | 1,890
Tdark 7 | 7,003
Tclin 5 | 602

IMPC Term

preweaning lethality, complete... 8 | 633
embryonic lethality prior to t... 4 | 187
decreased body weight 3 | 174
embryonic lethality prior to o... 3 | 148
abnormal retina morphology 2 | 100
decreased grip strength 2 | 123
hypoactivity 2 | 89
tremors 2 | 34
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hair texture 1 | 4
abnormal placement of pupils 1 | 4
abnormal retinal inner nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal spleen morphology 1 | 36
abnormal vertebrae morphology 1 | 14
anophthalmia 1 | 20
cataract 1 | 26
corneal opacity 1 | 25
decreased CD4-positive, CD25-p... 1 | 24
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 27
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
increased bone mineral density 1 | 52
increased circulating aspartat... 1 | 17
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
male infertility 1 | 62
narrow eye opening 1 | 15
preweaning lethality, incomple... 1 | 260
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small testis 1 | 37
thrombocytopenia 1 | 46

Disease

Cancer 83 | 2,346
ovarian cancer 76 | 8,484
osteosarcoma 72 | 7,933
lung cancer 46 | 4,466
medulloblastoma, large-cell 45 | 6,234
psoriasis 43 | 6,685
group 3 medulloblastoma 40 | 2,254
Breast cancer 38 | 3,094
malignant mesothelioma 37 | 3,162
glioblastoma 33 | 5,572
primitive neuroectodermal tumor 27 | 3,031
Carcinoma 26 | 2,147
Xeroderma pigmentosum 25 | 41
atypical teratoid / rhabdoid tumor 25 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
non-small cell lung cancer 24 | 2,798
Fanconi's anemia 23 | 50
Cockayne syndrome 22 | 54
Lynch syndrome 21 | 33
lung adenocarcinoma 21 | 2,713
Peripheral Neuropathy 20 | 303
Prostatic Neoplasms 19 | 471
Neoplastic Syndromes, Hereditary 18 | 48
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
Bloom syndrome 17 | 30
Mammary Neoplasms 17 | 410
Nijmegen breakage syndrome 17 | 23
invasive ductal carcinoma 17 | 2,950
oligodendroglioma 17 | 2,849
pediatric high grade glioma 17 | 2,712
Adenoma 16 | 165
sonic hedgehog group medulloblastoma 16 | 1,482
Ataxia telangiectasia 15 | 31
Familial adenomatous polyposis 15 | 31
astrocytic glioma 15 | 2,241
ependymoma 15 | 2,514
nasopharyngeal carcinoma 15 | 1,056
Waldenstrons macroglobulinemia 14 | 765
Werner syndrome 14 | 29
ductal carcinoma in situ 14 | 1,745
Anemia 13 | 252
Stomach Neoplasms 13 | 282
adrenocortical carcinoma 13 | 1,427
Colorectal Neoplasms 12 | 217
Hereditary Breast and Ovarian Cancer Syndrome 12 | 14
Photosensitive trichothiodystrophy 12 | 24
Pick disease 12 | 1,893
acute quadriplegic myopathy 12 | 1,157
colon cancer 12 | 1,475
dermatomyositis 12 | 933
subependymal giant cell astrocytoma 12 | 2,287
Microcephaly 11 | 149
Multiple myeloma 11 | 1,327
pancreatic cancer 11 | 2,300
tuberculosis 11 | 1,557
Fanconi Anemia 10 | 19
Intellectual disability 10 | 573
diabetes mellitus 10 | 1,663
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
ovarian neoplasm 10 | 97
pilocytic astrocytoma 10 | 3,086
Lung Neoplasms 9 | 171
Seckel syndrome 9 | 34
adult high grade glioma 9 | 2,148
astrocytoma 9 | 1,493
atypical teratoid/rhabdoid tumor 9 | 1,095
lung carcinoma 9 | 2,844
non primary Sjogren syndrome sicca 9 | 840
Bladder Neoplasm 8 | 109
Breast Cancer, Familial 8 | 12
Hereditary Nonpolyposis Colorectal Cancer 8 | 13
Melanoma 8 | 261
Pancreatic Neoplasm 8 | 79
Sebaceous adenoma 8 | 11
breast carcinoma 8 | 1,614
juvenile dermatomyositis 8 | 1,189
pancreatic carcinoma 8 | 567
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 2,087
Endometriosis 7 | 535
Malignant neoplasm of breast 7 | 63
Micronuclei, Chromosome-Defective 7 | 19
Neoplasm Metastasis 7 | 138
Neurodegenerative disease 7 | 383
Rheumatoid Arthritis 7 | 1,160
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
posterior fossa group A ependymoma 7 | 1,511
tuberculosis and treatment for 6 months 7 | 686
Adenocarcinoma of lung (disorder) 6 | 48
Adenoid Cystic Carcinoma 6 | 99
Aplastic anemia 6 | 18
DNA ligase IV deficiency 6 | 6
Hereditary Nonpolyposis Colorectal Neoplasms 6 | 8
Male infertility 6 | 170
Prostate cancer 6 | 172
acute myeloid leukemia 6 | 780
hepatocellular carcinoma 6 | 532
posterior fossa group B ependymoma 6 | 1,530
gastric cancer 5 | 430
medulloblastoma 5 | 1,524

Tissue

Digestive Tract 120 | 18,473
Endocrine System 120 | 18,512
Female tissues 120 | 18,647
Nervous System 120 | 18,561
Urinary Tract 120 | 18,444
Blood and immune system 119 | 17,995
Cardiovascular System 119 | 17,958
Respiratory system 119 | 17,484
Skin and soft tissues 119 | 18,115
Liver and Pancreas 118 | 18,136
Male tissues 118 | 17,969

Target Family

Non-IDG 62 | 11,971
Enzyme 46 | 4,146
Epigenetic 6 | 242
Kinase 6 | 634
Transcription Factor 3 | 1,400
GPCR 1 | 406

Compartment GO Term

DNA repair complex 124 | 124
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GTPase KRas KRAS Tbio Enzyme -3.75582 5694.2 421
Protein artemis DCLRE1C Tbio Non-IDG -1.63807 45.4 225
Nucleotide exchange factor SIL1 SIL1 Tbio Non-IDG -2.97229 967.7 187
N-glycosylase/DNA lyase OGG1 Tbio Enzyme -3.23405 1747.3 234
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.59332 3912.4 208
Double-strand break repair protein MRE11A MRE11 Tbio Non-IDG -1.95631 90.0 412
DNA ligase 4 LIG4 Tbio Enzyme -2.11773 136.0 194
DNA ligase 3 LIG3 Tbio Enzyme -2.71696 505.0 223
E3 ubiquitin-protein ligase RNF168 RNF168 Tbio Enzyme -1.46566 28.7 150
Cyclin-H CCNH Tbio Non-IDG -1.98840 89.8 354