Development Level

Tbio 90 | 10,625
Tchem 22 | 1,890
Tdark 7 | 7,003
Tclin 5 | 602

IMPC Term

preweaning lethality, complete... 8 | 633
embryonic lethality prior to t... 4 | 187
decreased body weight 3 | 174
embryonic lethality prior to o... 3 | 148
abnormal retina morphology 2 | 100
decreased grip strength 2 | 123
hypoactivity 2 | 89
tremors 2 | 34
abnormal coat/ hair morphology 1 | 18
abnormal cornea morphology 1 | 24
abnormal cranium morphology 1 | 32
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hair texture 1 | 4
abnormal placement of pupils 1 | 4
abnormal retinal inner nuclear... 1 | 5
abnormal retinal pigmentation 1 | 61
abnormal spleen morphology 1 | 36
abnormal vertebrae morphology 1 | 14
anophthalmia 1 | 20
cataract 1 | 26
corneal opacity 1 | 25
decreased CD4-positive, CD25-p... 1 | 24
decreased bone mineral density 1 | 126
decreased circulating aspartat... 1 | 27
decreased circulating chloride... 1 | 32
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
decreased total body fat amoun... 1 | 186
decreased total retina thickne... 1 | 20
increased bone mineral density 1 | 52
increased circulating aspartat... 1 | 17
increased circulating potassiu... 1 | 31
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased exploration in new e... 1 | 56
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular hem... 1 | 25
increased mean corpuscular vol... 1 | 91
increased prepulse inhibition 1 | 21
male infertility 1 | 62
narrow eye opening 1 | 15
preweaning lethality, incomple... 1 | 260
small heart 1 | 8
small kidney 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 11
small testis 1 | 37
thrombocytopenia 1 | 46

Disease

Cancer 83 | 2,346
ovarian cancer 78 | 8,492
osteosarcoma 72 | 7,933
lung cancer 47 | 4,473
medulloblastoma, large-cell 45 | 6,234
psoriasis 43 | 6,685
group 3 medulloblastoma 40 | 2,254
Breast cancer 38 | 3,099
malignant mesothelioma 37 | 3,163
glioblastoma 33 | 5,572
primitive neuroectodermal tumor 27 | 3,031
Carcinoma 26 | 2,147
Xeroderma pigmentosum 25 | 41
atypical teratoid / rhabdoid tumor 25 | 4,369
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,289
non-small cell lung cancer 24 | 2,798
Fanconi's anemia 23 | 50
Cockayne syndrome 22 | 54
Lynch syndrome 21 | 35
lung adenocarcinoma 21 | 2,714
Peripheral Neuropathy 20 | 303
Prostatic Neoplasms 19 | 471
Neoplastic Syndromes, Hereditary 18 | 48
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
Bloom syndrome 17 | 30
Mammary Neoplasms 17 | 410
Nijmegen breakage syndrome 17 | 23
invasive ductal carcinoma 17 | 2,950
oligodendroglioma 17 | 2,849
pediatric high grade glioma 17 | 2,712
Adenoma 16 | 165
sonic hedgehog group medulloblastoma 16 | 1,482
Ataxia telangiectasia 15 | 32
Familial adenomatous polyposis 15 | 33
astrocytic glioma 15 | 2,241
ependymoma 15 | 2,514
nasopharyngeal carcinoma 15 | 1,056
Waldenstrons macroglobulinemia 14 | 765
Werner syndrome 14 | 29
ductal carcinoma in situ 14 | 1,745
Anemia 13 | 252
Stomach Neoplasms 13 | 282
adrenocortical carcinoma 13 | 1,427
Colorectal Neoplasms 12 | 217
Fanconi Anemia 12 | 22
Hereditary Breast and Ovarian Cancer Syndrome 12 | 14
Photosensitive trichothiodystrophy 12 | 24
Pick disease 12 | 1,893
acute quadriplegic myopathy 12 | 1,157
colon cancer 12 | 1,475
dermatomyositis 12 | 967
subependymal giant cell astrocytoma 12 | 2,287
Microcephaly 11 | 149
Multiple myeloma 11 | 1,328
pancreatic cancer 11 | 2,300
tuberculosis 11 | 1,563
Intellectual disability 10 | 573
diabetes mellitus 10 | 1,663
esophageal atresia/tracheoesophageal fistula 10 | 19
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,956
ovarian neoplasm 10 | 97
pilocytic astrocytoma 10 | 3,086
Lung Neoplasms 9 | 171
Seckel syndrome 9 | 35
adult high grade glioma 9 | 2,148
astrocytoma 9 | 1,493
atypical teratoid/rhabdoid tumor 9 | 1,095
lung carcinoma 9 | 2,844
non primary Sjogren syndrome sicca 9 | 840
Bladder Neoplasm 8 | 109
Breast Cancer, Familial 8 | 12
Endometrial cancer 8 | 32
Hereditary Nonpolyposis Colorectal Cancer 8 | 13
Melanoma 8 | 261
Micronuclei, Chromosome-Defective 8 | 20
Pancreatic Neoplasm 8 | 79
Sebaceous adenoma 8 | 11
breast carcinoma 8 | 1,614
hepatocellular carcinoma 8 | 550
juvenile dermatomyositis 8 | 1,189
pancreatic carcinoma 8 | 567
pituitary cancer 8 | 1,972
ulcerative colitis 8 | 2,087
Endometriosis 7 | 535
Malignant neoplasm of breast 7 | 63
Neoplasm Metastasis 7 | 138
Neurodegenerative disease 7 | 383
Rheumatoid Arthritis 7 | 1,171
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
posterior fossa group A ependymoma 7 | 1,511
tuberculosis and treatment for 6 months 7 | 686
Adenocarcinoma of lung (disorder) 6 | 48
Adenoid Cystic Carcinoma 6 | 99
Aplastic anemia 6 | 19
DNA ligase IV deficiency 6 | 6
Male infertility 6 | 170
Prostate cancer 6 | 172
acute myeloid leukemia 6 | 785
gastric cancer 6 | 436
posterior fossa group B ependymoma 6 | 1,530

Tissue

Digestive Tract 120 | 18,473
Endocrine System 120 | 18,512
Female tissues 120 | 18,647
Nervous System 120 | 18,561
Urinary Tract 120 | 18,444
Blood and immune system 119 | 17,995
Cardiovascular System 119 | 17,958
Respiratory system 119 | 17,484
Skin and soft tissues 119 | 18,115
Liver and Pancreas 118 | 18,136
Male tissues 118 | 17,969

Target Family

Non-IDG 62 | 11,969
Enzyme 46 | 4,146
Epigenetic 6 | 242
Kinase 6 | 634
Transcription Factor 3 | 1,400
GPCR 1 | 408

Compartment GO Term

DNA repair complex 124 | 124
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,612 | 13,612
Intracellular part 13,475 | 13,475
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,353 | 10,353
Membrane 8,871 | 8,871
Organelle part 8,169 | 8,169
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,831 | 7,831
Nucleus 7,577 | 7,577
Membrane part 6,469 | 6,469
Cytosol 6,034 | 6,034
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,930 | 4,930
Extracellular region 4,607 | 4,607
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,874 | 3,874
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,592 | 2,592
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,530 | 1,530
Cell projection 1,425 | 1,425
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,092 | 1,092
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,084 | 1,084
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 988 | 988
Nucleoli 950 | 950
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 815 | 815
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 656 | 656
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.02098 96.6 198
Adenine DNA glycosylase MUTYH Tbio Enzyme -2.83418 699.9 239
Tyrosyl-DNA phosphodiesterase 1 TDP1 Tchem Enzyme -2.03905 126.5 179
Crossover junction endonuclease MUS81 MUS81 Tbio Enzyme -2.03597 106.6 73
Methylated-DNA--protein-cysteine methyltransferase MGMT Tchem Enzyme -3.10644 1345.2 435
BRCA1-associated RING domain protein 1 BARD1 Tbio Non-IDG -2.06127 111.2 208
Cell cycle checkpoint control protein RAD9A RAD9A Tbio Non-IDG -2.13819 136.3 864
UV excision repair protein RAD23 homolog A RAD23A Tbio Non-IDG -1.57282 35.7 282
UV excision repair protein RAD23 homolog B RAD23B Tbio Non-IDG -1.98667 88.6 284
DNA endonuclease RBBP8 RBBP8 Tbio Enzyme -2.13927 142.2 263