Development Level

Tbio 97 | 11,651
Tchem 22 | 1,388
Tdark 7 | 6,593
Tclin 5 | 612

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to t... 6 | 278
embryonic lethality prior to o... 4 | 239
preweaning lethality, incomple... 4 | 499
hypoactivity 3 | 132
abnormal embryo size 2 | 220
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
decreased body weight 2 | 161
male infertility 2 | 123
tremors 2 | 39
abnormal behavior 1 | 298
abnormal blood vessel morpholo... 1 | 5
abnormal chorioallantoic fusio... 1 | 8
abnormal coat- hair morphology 1 | 19
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal embryo development 1 | 7
abnormal embryo turning 1 | 31
abnormal eye size 1 | 7
abnormal forebrain development 1 | 20
abnormal hair texture 1 | 4
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal pharyngeal arch morph... 1 | 8
abnormal placement of pupils 1 | 6
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal somite shape 1 | 5
abnormal spinal cord morpholog... 1 | 9
abnormal spleen morphology 1 | 55
abnormal vertebrae morphology 1 | 18
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
enlarged heart 1 | 210
female infertility 1 | 60
increased bone mineral density 1 | 72
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
pale yolk sac 1 | 25
pallor 1 | 34
small heart 1 | 10
small kidney 1 | 16
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small testis 1 | 58

Disease

Carcinoma 98 | 11,493
Cancer 86 | 2,499
ovarian cancer 86 | 8,520
osteosarcoma 75 | 7,950
group 3 medulloblastoma 54 | 4,104
lung cancer 53 | 4,740
medulloblastoma, large-cell 47 | 6,241
psoriasis 44 | 6,694
glioblastoma 43 | 5,792
Breast cancer 41 | 3,578
malignant mesothelioma 39 | 3,232
atypical teratoid / rhabdoid tumor 36 | 5,112
Autosomal recessive predisposition 32 | 1,442
Kidney cancer 30 | 2,613
Xeroderma pigmentosum 30 | 43
Intellectual disability 29 | 1,016
primitive neuroectodermal tumor 29 | 3,035
Short stature 27 | 531
Fanconi anemia 26 | 56
ependymoma 26 | 4,679
non-small cell lung cancer 26 | 2,890
Dull intelligence 25 | 645
Low intelligence 25 | 645
Mental Retardation 25 | 645
Mental deficiency 25 | 645
Poor school performance 25 | 645
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
Cockayne syndrome 24 | 60
Prostatic Neoplasms 23 | 495
Small head 23 | 374
Lynch syndrome 22 | 35
Seizures 22 | 596
adult high grade glioma 22 | 3,801
lung adenocarcinoma 22 | 2,716
Breast Neoplasms 21 | 445
Epilepsy 21 | 792
Mammary Neoplasms 21 | 425
Cryptorchidism 20 | 296
Cognitive delay 19 | 608
Global developmental delay 19 | 608
Melanoma 19 | 711
Mental and motor retardation 19 | 608
Strabismus 19 | 270
Muscle hypotonia 18 | 571
Nijmegen breakage syndrome 18 | 24
astrocytic glioma 18 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
Adenoma 17 | 167
Bloom syndrome 17 | 29
Fatigue 17 | 182
Stomach Neoplasms 17 | 300
invasive ductal carcinoma 17 | 2,951
oligodendroglioma 17 | 2,850
Ataxia telangiectasia 16 | 34
Hypoplastic mandible condyle 16 | 275
Mandibular hypoplasia 16 | 275
Micrognathism 16 | 275
breast carcinoma 16 | 1,638
nasopharyngeal carcinoma 16 | 1,058
pancreatic cancer 16 | 2,398
Anemia 15 | 365
Basal cell carcinoma 15 | 54
Chromosome Breakage 15 | 36
Familial adenomatous polyposis 15 | 32
adrenocortical carcinoma 15 | 1,428
hypopigmented skin patch 15 | 59
Acquired scoliosis 14 | 281
Cataract 14 | 297
Curvature of spine 14 | 282
Schizophrenia 14 | 1,160
acute quadriplegic myopathy 14 | 1,158
colon cancer 14 | 1,478
diabetes mellitus 14 | 1,728
ductal carcinoma in situ 14 | 1,745
Colorectal Neoplasms 13 | 243
Hereditary Breast and Ovarian Cancer Syndrome 13 | 14
Hypogonadism 13 | 173
Increased chromosomal breakage 13 | 27
Lymphoma 13 | 81
Thrombocytopenia 13 | 197
Waldenstrons macroglobulinemia 13 | 765
Werner syndrome 13 | 29
Xeroderma pigmentosum group F 13 | 22
tuberculosis 13 | 2,010
Basal cell nevi 12 | 23
Death in early childhood 12 | 82
Death in infancy 12 | 82
Dry skin 12 | 75
Endometrial cancer 12 | 311
Irregular hyperpigmentation 12 | 33
Lens Opacities 12 | 231
Lung Neoplasms 12 | 232
Muscle Hypertonia 12 | 88
Photosensitivity of skin 12 | 51
Sensorineural Hearing Loss (disorder) 12 | 284
Xeroderma pigmentosum group D 12 | 33
Xerosis 12 | 75
dermatomyositis 12 | 966
subependymal giant cell astrocytoma 12 | 2,287
Decreased size of eyeball 11 | 97

Tissue

Endocrine System 125 | 18,159
Blood and immune system 124 | 16,909
Digestive Tract 124 | 17,369
Female tissues 124 | 17,400
Liver and Pancreas 124 | 16,750
Male tissues 124 | 17,142
Nervous System 124 | 16,725
Respiratory system 124 | 16,393
Skin and soft tissues 124 | 17,230
Urinary Tract 124 | 16,678
Cardiovascular System 123 | 15,192

Target Family

Non-IDG 63 | 12,091
Enzyme 51 | 4,145
Epigenetic 7 | 242
Kinase 6 | 634
Transcription Factor 3 | 1,400
GPCR 1 | 408

Compartment GO Term

DNA repair complex 131 | 131
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
General transcription factor IIH subunit 1 GTF2H1 Tbio Non-IDG -1.65323 46.0 231
Mitochondrial inner membrane protease ATP23 homolog ATP23 Tdark Enzyme -0.86878 7.67 43
MutS protein homolog 5 MSH5 Tbio Non-IDG -1.75314 0.00000 142
BRCA1-A complex subunit RAP80 UIMC1 Tbio Non-IDG -1.69622 52.7 176
REST corepressor 1 RCOR1 Tbio Transcription Factor -1.96775 81.2 0
DNA polymerase delta catalytic subunit POLD1 Tclin Enzyme -2.06760 110.4 225
Bifunctional polynucleotide phosphatase/kinase PNKP Tbio Enzyme -1.79273 59.8 231
Protein artemis DCLRE1C Tbio Non-IDG -2.27419 184.9 252
DNA repair protein complementing XP-C cells XPC Tbio Non-IDG -2.21142 154.0 208
Partner and localizer of BRCA2 PALB2 Tbio Non-IDG -2.16005 165.4 154