Development Level

Tbio 51 | 11,651
Tchem 33 | 1,388
Tclin 16 | 612

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal heart morphology 5 | 162
preweaning lethality, incomple... 5 | 499
abnormal embryo size 4 | 220
enlarged heart 3 | 210
abnormal embryo turning 2 | 31
abnormal lens morphology 2 | 81
abnormal pharyngeal arch morph... 2 | 8
cataract 2 | 92
decreased circulating insulin ... 2 | 76
decreased circulating triglyce... 2 | 79
edema 2 | 59
embryonic growth retardation 2 | 106
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
increased circulating HDL chol... 2 | 80
increased circulating choleste... 2 | 66
increased total body fat amoun... 2 | 134
male infertility 2 | 123
abnormal behavioral response t... 1 | 66
abnormal blood vessel morpholo... 1 | 5
abnormal bone mineralization 1 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal coat- hair morphology 1 | 19
abnormal embryo development 1 | 7
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal forebrain development 1 | 20
abnormal hair texture 1 | 4
abnormal head morphology 1 | 10
abnormal hindbrain development 1 | 16
abnormal humerus morphology 1 | 11
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal somite shape 1 | 5
abnormal spleen morphology 1 | 55
abnormal startle reflex 1 | 15
abnormal testis morphology 1 | 43
abnormal visceral yolk sac mor... 1 | 6
abnormal vitelline vasculature... 1 | 6
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating aspartat... 1 | 34
decreased heart left ventricle... 1 | 28
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased neutrophil cell numb... 1 | 42
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
enlarged epididymis 1 | 31
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112
limb grasping 1 | 41
mammalian phenotype 1 | 17
microphthalmia 1 | 26
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality 1 | 28
short tibia 1 | 97
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thin ventricular wall 1 | 24
urinary bladder obstruction 1 | 4

Disease

Cancer 81 | 2,499
ovarian cancer 70 | 8,520
Carcinoma 65 | 11,493
lung cancer 63 | 4,740
glioblastoma 60 | 5,792
psoriasis 60 | 6,694
osteosarcoma 54 | 7,950
malignant mesothelioma 53 | 3,232
Breast cancer 48 | 3,578
medulloblastoma, large-cell 45 | 6,241
atypical teratoid / rhabdoid tumor 42 | 5,112
non-small cell lung cancer 42 | 2,890
lung adenocarcinoma 41 | 2,716
group 3 medulloblastoma 40 | 4,104
diabetes mellitus 37 | 1,728
invasive ductal carcinoma 37 | 2,951
adult high grade glioma 36 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 36 | 3,291
Breast Neoplasms 34 | 445
Mammary Neoplasms 34 | 425
ependymoma 33 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 33 | 2,989
primitive neuroectodermal tumor 33 | 3,035
Schizophrenia 31 | 1,160
adrenocortical carcinoma 31 | 1,428
Kidney disease 29 | 430
Prostatic Neoplasms 29 | 495
Stomach Neoplasms 28 | 300
Endometriosis 27 | 540
ductal carcinoma in situ 27 | 1,745
pancreatic cancer 27 | 2,398
ulcerative colitis 27 | 1,819
Adenoma 26 | 167
breast carcinoma 26 | 1,638
Carcinoma, Hepatocellular 25 | 228
Heart disease 25 | 306
Liver carcinoma 25 | 240
Lung Neoplasms 25 | 232
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
nasopharyngeal carcinoma 25 | 1,058
Adenocarcinoma 24 | 122
oligodendroglioma 24 | 2,850
Astrocytoma, Pilocytic 23 | 3,081
Liver disease 23 | 237
colon cancer 23 | 1,478
Colonic Neoplasms 22 | 142
Neoplasm Metastasis 22 | 168
interstitial cystitis 22 | 2,312
Liver Cirrhosis, Experimental 21 | 769
Neoplasm Invasiveness 21 | 161
Obesity 21 | 678
Vascular disease 21 | 319
Hypertension 20 | 396
Kidney cancer 20 | 2,613
pituitary cancer 20 | 1,972
Alzheimer's disease 19 | 658
Depressive disorder 19 | 409
Squamous cell carcinoma 19 | 129
lung carcinoma 19 | 2,843
tuberculosis 19 | 2,010
Asthma 18 | 385
Carcinoma, Squamous Cell 18 | 110
Cerebrovascular disease 18 | 238
Colorectal Neoplasms 18 | 243
Lung disease 18 | 142
astrocytoma 18 | 1,146
subependymal giant cell astrocytoma 18 | 2,287
Arthritis 17 | 290
Atherosclerosis 17 | 291
Liver Neoplasms, Experimental 17 | 59
cystic fibrosis 17 | 1,696
Autosomal recessive predisposition 16 | 1,442
Bladder Neoplasm 16 | 112
Cell Transformation, Neoplastic 16 | 97
Melanoma 16 | 711
Ovarian Neoplasms 16 | 102
Toxic encephalopathy 16 | 141
Urinary Bladder Neoplasms 16 | 114
astrocytic glioma 16 | 2,597
ovarian neoplasm 16 | 99
Atopic dermatitis 15 | 952
Neoplastic Cell Transformation 15 | 89
acute quadriplegic myopathy 15 | 1,158
medulloblastoma 15 | 720
Anemia 14 | 365
Bipolar Disorder 14 | 666
Brain Ischemia 14 | 110
Coronary artery disease 14 | 268
Diabetes Mellitus, Experimental 14 | 108
Eye disease 14 | 62
Hypertensive disease 14 | 292
Major Depressive Disorder 14 | 301
Mammary Neoplasms, Experimental 14 | 154
Osteoporosis 14 | 363
Pancreatic Neoplasm 14 | 85
Pancreatic Neoplasms 14 | 85
Pulmonary Fibrosis 14 | 106
Reperfusion Injury 14 | 86
Rheumatoid arthritis 14 | 1,191
Mental Depression 13 | 333

Tissue

Blood and immune system 98 | 16,909
Digestive Tract 98 | 17,369
Endocrine System 97 | 18,159
Female tissues 97 | 17,400
Male tissues 97 | 17,142
Nervous System 97 | 16,725
Respiratory system 97 | 16,393
Skin and soft tissues 97 | 17,230
Urinary Tract 97 | 16,678
Liver and Pancreas 96 | 16,750
Cardiovascular System 92 | 15,192

Target Family

Non-IDG 49 | 12,091
Enzyme 27 | 4,145
Kinase 13 | 634
Transcription Factor 5 | 1,400
Epigenetic 3 | 242
Nuclear Receptor 3 | 48

Compartment GO Term

DNA polymerase processivity fa... 100 | 100
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Estrogen receptor ESR1 Tclin Nuclear Receptor -4.00480 8421.6 2610
Ubiquitin carboxyl-terminal hydrolase 1 USP1 Tchem Enzyme -1.88853 73.3 271
Chromosome transmission fidelity protein 18 homolog CHTF18 Tbio Non-IDG -1.51235 35.5 138
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.71197 390.1 730
Matrix metalloproteinase-9 MMP9 Tchem Enzyme -3.96102 8811.6 1442
Denticleless protein homolog DTL Tbio Non-IDG -1.63065 50.0 160