Development Level

Tbio 70 | 11,651
Tdark 16 | 6,593
Tchem 10 | 1,388
Tclin 2 | 612

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 2 | 220
abnormal bone structure 1 | 187
abnormal eye morphology 1 | 68
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal stomach morphology 1 | 10
abnormal tooth morphology 1 | 24
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased food intake 1 | 13
decreased mean corpuscular vol... 1 | 79
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
male infertility 1 | 123
polycystic kidney 1 | 15
prolonged QRS complex duration 1 | 8
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 50 | 11,493
psoriasis 45 | 6,694
lung cancer 42 | 4,740
ovarian cancer 41 | 8,520
osteosarcoma 40 | 7,950
Breast cancer 39 | 3,578
atypical teratoid / rhabdoid tumor 33 | 5,112
glioblastoma 32 | 5,792
lung adenocarcinoma 32 | 2,716
medulloblastoma, large-cell 31 | 6,241
invasive ductal carcinoma 30 | 2,951
group 3 medulloblastoma 27 | 4,104
malignant mesothelioma 25 | 3,232
non-small cell lung cancer 25 | 2,890
intraductal papillary-mucinous carcinoma (IPMC) 24 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 23 | 3,291
primitive neuroectodermal tumor 23 | 3,035
Cancer 22 | 2,499
ductal carcinoma in situ 21 | 1,745
colon cancer 20 | 1,478
breast carcinoma 19 | 1,638
Kidney cancer 16 | 2,613
adrenocortical carcinoma 14 | 1,428
ependymoma 14 | 4,679
pancreatic cancer 14 | 2,398
adult high grade glioma 13 | 3,801
Multiple myeloma 12 | 1,332
diabetes mellitus 12 | 1,728
Intellectual disability 9 | 1,016
Pick disease 9 | 1,894
Schizophrenia 9 | 1,160
Waldenstrons macroglobulinemia 9 | 765
astrocytoma 9 | 1,146
cystic fibrosis 9 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
non-small cell lung carcinoma 9 | 317
oligodendroglioma 9 | 2,850
pediatric high grade glioma 9 | 1,064
Astrocytoma, Pilocytic 8 | 3,081
Endometriosis 8 | 540
acute myeloid leukemia 8 | 783
cutaneous lupus erythematosus 8 | 1,057
group 4 medulloblastoma 8 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Male infertility 7 | 206
Rheumatoid arthritis 7 | 1,191
acute quadriplegic myopathy 7 | 1,158
lung carcinoma 7 | 2,843
pancreatic carcinoma 7 | 562
Atopic dermatitis 6 | 952
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
astrocytic glioma 6 | 2,597
dermatomyositis 6 | 966
hepatocellular carcinoma 6 | 547
nasopharyngeal carcinoma 6 | 1,058
posterior fossa group A ependymoma 6 | 468
ulcerative colitis 6 | 1,819
Cognitive delay 5 | 608
Cryptorchidism 5 | 296
Dull intelligence 5 | 645
Epilepsy 5 | 792
Feeding difficulties in infancy 5 | 175
Global developmental delay 5 | 608
Infertility 5 | 188
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Poor school performance 5 | 645
Seizures 5 | 596
Short stature 5 | 531
aldosterone-producing adenoma 5 | 665
gastric cancer 5 | 459
inflammatory breast cancer 5 | 286
interstitial cystitis 5 | 2,312
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
tuberculosis 5 | 2,010
Adenoid Cystic Carcinoma 4 | 99
Brachydactyly 4 | 156
Carcinoma, Adenoid Cystic 4 | 99
Cleft Palate 4 | 271
Cockayne syndrome 4 | 60
Congenital deafness 4 | 185
Deafness 4 | 198
Down syndrome 4 | 499
Hearing Loss, Partial 4 | 185
Liver cancer 4 | 604
Lupus erythematosus 4 | 57
Muscle hypotonia 4 | 571
Neurodegenerative disease 4 | 414
Schimke immuno-osseous dysplasia 4 | 8
Small head 4 | 374
Strabismus 4 | 270
Systemic scleroderma 4 | 60
hearing impairment 4 | 199
juvenile dermatomyositis 4 | 1,187

Tissue

Endocrine System 98 | 18,159
Female tissues 96 | 17,400
Blood and immune system 95 | 16,909
Digestive Tract 95 | 17,369
Skin and soft tissues 93 | 17,230
Male tissues 91 | 17,142
Nervous System 91 | 16,725
Respiratory system 91 | 16,393
Urinary Tract 91 | 16,678
Liver and Pancreas 90 | 16,750
Cardiovascular System 88 | 15,192

Target Family

Non-IDG 77 | 12,091
Epigenetic 15 | 242
Enzyme 4 | 4,145
Transcription Factor 2 | 1,400

Compartment GO Term

DNA packaging complex 98 | 98
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protamine-2 PRM2 Tbio Non-IDG -2.03817 103.5 37
Histone acetyltransferase KAT6B KAT6B Tbio Epigenetic -2.30232 201.0 58
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.73322 567.0 386
Caspase-3 CASP3 Tchem Enzyme -4.32112 18132.3 1689
Histone deacetylase 1 HDAC1 Tclin Epigenetic -3.03775 954.3 1201
Condensin-2 complex subunit D3 NCAPD3 Tbio Non-IDG -1.18079 14.7 141
Condensin-2 complex subunit G2 NCAPG2 Tbio Non-IDG -0.75957 5.48 110
Histone H2A type 1-A HIST1H2AA Tbio Non-IDG -0.84480 8.19 69
Holliday junction recognition protein HJURP Tbio Non-IDG -1.45205 24.7 91
Histone H3.3 H3F3B Tbio Non-IDG -2.14998 122.5 458