Development Level

Tbio 63 | 10,625
Tdark 19 | 7,003
Tchem 12 | 1,890
Tclin 2 | 602

IMPC Phenotype

decreased lean body mass 3 | 195
decreased body length 2 | 108
decreased total body fat amoun... 2 | 186
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hindbrain development 1 | 24
abnormal maxilla morphology 1 | 16
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal tooth morphology 1 | 24
anophthalmia 1 | 20
decreased Ly6C low monocyte nu... 1 | 23
decreased bone mineral content 1 | 157
decreased mean corpuscular vol... 1 | 50
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating choleste... 1 | 53
increased effector memory CD4-... 1 | 15
increased grip strength 1 | 83
increased mean platelet volume 1 | 19
increased plasma cell number 1 | 5
male infertility 1 | 62
microphthalmia 1 | 15
prolonged QRS complex duration 1 | 2
short tibia 1 | 82
tremors 1 | 34

Disease

psoriasis 44 | 6,685
ovarian cancer 41 | 8,491
osteosarcoma 40 | 7,933
lung cancer 38 | 4,473
Breast cancer 34 | 3,098
lung adenocarcinoma 32 | 2,714
glioblastoma 31 | 5,572
medulloblastoma, large-cell 30 | 6,234
invasive ductal carcinoma 29 | 2,950
atypical teratoid / rhabdoid tumor 27 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
Cancer 22 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
malignant mesothelioma 22 | 3,163
non-small cell lung cancer 22 | 2,798
primitive neuroectodermal tumor 22 | 3,031
ductal carcinoma in situ 20 | 1,745
breast carcinoma 19 | 1,614
colon cancer 19 | 1,475
pediatric high grade glioma 17 | 2,712
group 3 medulloblastoma 16 | 2,254
adrenocortical carcinoma 13 | 1,427
pancreatic cancer 13 | 2,300
Multiple myeloma 12 | 1,327
diabetes mellitus 12 | 1,663
non-small cell lung carcinoma 10 | 413
posterior fossa group A ependymoma 10 | 1,511
Carcinoma 9 | 2,147
Pick disease 9 | 1,893
Waldenstrons macroglobulinemia 9 | 764
astrocytoma 9 | 1,493
cystic fibrosis 9 | 1,670
ependymoma 9 | 2,514
group 4 medulloblastoma 9 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
oligodendroglioma 9 | 2,849
sonic hedgehog group medulloblastoma 9 | 1,482
Endometriosis 8 | 535
acute myeloid leukemia 8 | 785
cutaneous lupus erythematosus 8 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
pilocytic astrocytoma 8 | 3,086
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Intellectual disability 7 | 573
Rheumatoid Arthritis 7 | 1,170
acute quadriplegic myopathy 7 | 1,157
lung carcinoma 7 | 2,844
pancreatic carcinoma 7 | 567
ulcerative colitis 7 | 2,087
Atopic dermatitis 6 | 944
IGA Glomerulonephritis 6 | 454
Male infertility 6 | 170
Mammary Neoplasms 6 | 410
astrocytic glioma 6 | 2,241
atypical teratoid/rhabdoid tumor 6 | 1,095
dermatomyositis 6 | 966
hepatocellular carcinoma 6 | 550
inflammatory breast cancer 6 | 404
nasopharyngeal carcinoma 6 | 1,056
aldosterone-producing adenoma 5 | 664
gastric cancer 5 | 436
interstitial cystitis 5 | 2,299
medulloblastoma 5 | 1,524
progressive supranuclear palsy 5 | 674
spina bifida 5 | 1,064
tuberculosis 5 | 1,563
Down syndrome 4 | 548
Infertility 4 | 163
Lupus erythematosus 4 | 80
Schimke immuno-osseous dysplasia 4 | 9
Systemic scleroderma 4 | 66
adult high grade glioma 4 | 2,148
juvenile dermatomyositis 4 | 1,189
Adenoid Cystic Carcinoma 3 | 99
Alpha thalassemia 3 | 10
CREST syndrome 3 | 10
Calcinosis 3 | 63
Cerebrovascular disease 3 | 231
Cleft palate 3 | 125
Cockayne syndrome 3 | 54
Connective tissue disease 3 | 59
Crohn's disease 3 | 304
Dementia 3 | 129
Gaucher disease type 1 3 | 171
Huntington's disease 3 | 72
Leishmaniasis 3 | 49
Neurodegenerative disease 3 | 383
Obesity 3 | 616
Parkinson's disease 3 | 364
Progressive relapsing multiple sclerosis 3 | 18
Schizophrenia 3 | 503
Williams-Beuren syndrome 3 | 45
primary Sjogren syndrome 3 | 788
Gastric antral vascular ectasia 2 | 11
Heart disease 2 | 279
Prostate cancer 2 | 172
esophageal adenocarcinoma 2 | 737
head and neck cancer 2 | 270
tuberculosis and treatment for 6 months 2 | 686

Tissue

Female tissues 95 | 18,646
Blood and immune system 93 | 17,994
Endocrine System 93 | 18,511
Male tissues 93 | 17,968
Nervous System 93 | 18,560
Urinary Tract 93 | 18,443
Cardiovascular System 92 | 17,957
Digestive Tract 91 | 18,472
Liver and Pancreas 89 | 18,135
Respiratory system 88 | 17,483
Skin and soft tissues 81 | 18,114

Target Family

Non-IDG 76 | 11,969
Epigenetic 15 | 242
Enzyme 3 | 4,146
Transcription Factor 2 | 1,400

Compartment GO Term

DNA packaging complex 96 | 96
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone H2A type 1-J HIST1H2AJ Tdark Non-IDG -0.13212 1.19 10
Histone H2B type 1-M HIST1H2BM Tdark Non-IDG 0.16 0.33 20
Histone H2B type 1-L HIST1H2BL Tdark Non-IDG 0.35 0.40 42
Histone H2B type 1-N HIST1H2BN Tdark Non-IDG -1.51554 30.2 48
Histone H2A type 1-B/E HIST1H2AB Tbio Non-IDG -1.26707 18.9 109
Structural maintenance of chromosomes protein 6 SMC6 Tbio Non-IDG -1.40489 19.9 106
Histone acetyltransferase KAT6B KAT6B Tchem Epigenetic -2.27196 178.8 53
Structural maintenance of chromosomes protein 2 SMC2 Tbio Non-IDG -0.69216 5.13 167
Twist-related protein 1 TWIST1 Tbio Transcription Factor -3.89181 7558.3 366
Histone H2A type 1-H HIST1H2AH Tbio Non-IDG -1.14502 13.7 81