Development Level

Tbio 63 | 10,625
Tdark 19 | 7,003
Tchem 12 | 1,890
Tclin 2 | 602

IMPC Term

decreased lean body mass 3 | 195
decreased body length 2 | 108
decreased total body fat amoun... 2 | 186
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal hindbrain development 1 | 24
abnormal maxilla morphology 1 | 16
abnormal neural tube closure 1 | 37
abnormal retina morphology 1 | 100
abnormal tooth morphology 1 | 24
anophthalmia 1 | 20
decreased Ly6C low monocyte nu... 1 | 23
decreased bone mineral content 1 | 157
decreased mean corpuscular vol... 1 | 50
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
hyperactivity 1 | 108
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased bone mineral density 1 | 52
increased circulating amylase ... 1 | 13
increased circulating choleste... 1 | 53
increased effector memory CD4-... 1 | 15
increased grip strength 1 | 83
increased mean platelet volume 1 | 19
increased plasma cell number 1 | 5
male infertility 1 | 62
microphthalmia 1 | 15
prolonged QRS complex duration 1 | 2
short tibia 1 | 82
tremors 1 | 34

Disease

psoriasis 44 | 6,685
ovarian cancer 41 | 8,484
osteosarcoma 40 | 7,933
lung cancer 38 | 4,466
Breast cancer 34 | 3,094
lung adenocarcinoma 32 | 2,713
glioblastoma 31 | 5,572
medulloblastoma, large-cell 30 | 6,234
invasive ductal carcinoma 29 | 2,950
atypical teratoid / rhabdoid tumor 27 | 4,369
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,988
Cancer 22 | 2,346
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,289
malignant mesothelioma 22 | 3,162
non-small cell lung cancer 22 | 2,798
primitive neuroectodermal tumor 22 | 3,031
ductal carcinoma in situ 20 | 1,745
breast carcinoma 19 | 1,614
colon cancer 19 | 1,475
pediatric high grade glioma 17 | 2,712
group 3 medulloblastoma 16 | 2,254
adrenocortical carcinoma 13 | 1,427
pancreatic cancer 13 | 2,300
Multiple myeloma 12 | 1,327
diabetes mellitus 12 | 1,663
non-small cell lung carcinoma 10 | 413
posterior fossa group A ependymoma 10 | 1,511
Carcinoma 9 | 2,147
Pick disease 9 | 1,893
Waldenstrons macroglobulinemia 9 | 765
astrocytoma 9 | 1,493
cystic fibrosis 9 | 1,665
ependymoma 9 | 2,514
group 4 medulloblastoma 9 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
oligodendroglioma 9 | 2,849
sonic hedgehog group medulloblastoma 9 | 1,482
Endometriosis 8 | 535
acute myeloid leukemia 8 | 780
cutaneous lupus erythematosus 8 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
pilocytic astrocytoma 8 | 3,086
pituitary cancer 8 | 1,972
subependymal giant cell astrocytoma 8 | 2,287
Intellectual disability 7 | 573
Rheumatoid Arthritis 7 | 1,160
acute quadriplegic myopathy 7 | 1,157
lung carcinoma 7 | 2,844
pancreatic carcinoma 7 | 567
ulcerative colitis 7 | 2,087
Atopic dermatitis 6 | 944
IGA Glomerulonephritis 6 | 454
Male infertility 6 | 170
Mammary Neoplasms 6 | 410
astrocytic glioma 6 | 2,241
atypical teratoid/rhabdoid tumor 6 | 1,095
dermatomyositis 6 | 933
hepatocellular carcinoma 6 | 532
inflammatory breast cancer 6 | 404
nasopharyngeal carcinoma 6 | 1,056
aldosterone-producing adenoma 5 | 664
gastric cancer 5 | 430
interstitial cystitis 5 | 2,299
medulloblastoma 5 | 1,524
progressive supranuclear palsy 5 | 674
spina bifida 5 | 1,064
tuberculosis 5 | 1,557
Down syndrome 4 | 548
Infertility 4 | 163
Lupus erythematosus 4 | 80
Schimke immuno-osseous dysplasia 4 | 9
Systemic scleroderma 4 | 66
adult high grade glioma 4 | 2,148
juvenile dermatomyositis 4 | 1,189
Adenoid Cystic Carcinoma 3 | 99
Alpha thalassemia 3 | 9
CREST syndrome 3 | 10
Calcinosis 3 | 62
Cerebrovascular disease 3 | 231
Cleft palate 3 | 125
Cockayne syndrome 3 | 54
Connective tissue disease 3 | 59
Crohn's disease 3 | 304
Dementia 3 | 129
Gaucher disease type 1 3 | 171
Huntington's disease 3 | 72
Leishmaniasis 3 | 49
Neurodegenerative disease 3 | 383
Obesity 3 | 616
Parkinson's disease 3 | 364
Progressive relapsing multiple sclerosis 3 | 18
Williams-Beuren syndrome 3 | 45
primary Sjogren syndrome 3 | 789
Gastric antral vascular ectasia 2 | 11
Heart disease 2 | 279
Lung disease 2 | 132
Prostate cancer 2 | 172
esophageal adenocarcinoma 2 | 737
head and neck cancer 2 | 270
tuberculosis and treatment for 6 months 2 | 686

Tissue

Female tissues 95 | 18,647
Blood and immune system 93 | 17,995
Endocrine System 93 | 18,512
Male tissues 93 | 17,969
Nervous System 93 | 18,561
Urinary Tract 93 | 18,444
Cardiovascular System 92 | 17,958
Digestive Tract 91 | 18,473
Liver and Pancreas 89 | 18,136
Respiratory system 88 | 17,484
Skin and soft tissues 81 | 18,115

Target Family

Non-IDG 76 | 11,971
Epigenetic 15 | 242
Enzyme 3 | 4,146
Transcription Factor 2 | 1,400

Compartment GO Term

DNA packaging complex 96 | 96
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysine-specific histone demethylase 1B KDM1B Tbio Epigenetic -1.39308 24.2 69
Histone H3-like centromeric protein A CENPA Tbio Non-IDG -2.68837 532.8 347
DNA topoisomerase 1 TOP1 Tclin Enzyme -3.59332 3912.4 208
Histone H4 HIST2H4A Tbio Non-IDG -2.57230 138.5 770
Histone H2B type 1-C/E/F/G/I HIST1H2BC Tbio Non-IDG -1.35785 22.1 103
Histone H3.3 H3F3B Tbio Non-IDG -2.06154 100.6 415
Transcription activator BRG1 SMARCA4 Tchem Epigenetic -2.81672 663.0 295
Probable global transcription activator SNF2L2 SMARCA2 Tchem Epigenetic -2.53909 331.1 154
Holliday junction recognition protein HJURP Tbio Non-IDG -1.37643 22.0 78
Histone acetyltransferase p300 EP300 Tchem Epigenetic -3.75838 5701.8 723