Development Level

Tbio 11 | 11,445
Tchem 3 | 1,598

IMPC Phenotype

abnormal vertebrae morphology 1 | 18
decreased body weight 1 | 161
decreased circulating glycerol... 1 | 16
increased circulating triglyce... 1 | 42
increased startle reflex 1 | 112
tremors 1 | 39

Disease

osteosarcoma 11 | 7,950
Carcinoma 10 | 11,493
Cancer 9 | 2,499
group 3 medulloblastoma 8 | 4,104
Severe combined immunodeficiency 7 | 51
DNA ligase IV deficiency 6 | 7
lung cancer 6 | 4,740
malignant mesothelioma 6 | 3,232
medulloblastoma, large-cell 6 | 6,241
ovarian cancer 6 | 8,520
Kidney cancer 5 | 2,613
Werner syndrome 5 | 29
atypical teratoid / rhabdoid tumor 5 | 5,112
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
Ataxia telangiectasia 4 | 34
Microcephaly 4 | 166
Nijmegen breakage syndrome 4 | 24
primitive neuroectodermal tumor 4 | 3,035
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
Chromosome Breakage 3 | 36
Erythema 3 | 58
Increased chromosomal breakage 3 | 27
Prostatic Neoplasms 3 | 495
Schizophrenia 3 | 1,160
Short stature 3 | 531
Small head 3 | 374
Xeroderma pigmentosum 3 | 43
acute quadriplegic myopathy 3 | 1,158
astrocytic glioma 3 | 2,597
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
oligodendroglioma 3 | 2,850
Acute blood cancer 2 | 6
Acute leukemia 2 | 15
Adenocarcinoma of lung 2 | 142
Adenoid Cystic Carcinoma 2 | 99
Autosomal recessive predisposition 2 | 1,442
Biparietal narrowing 2 | 28
Bladder Neoplasm 2 | 112
Bloom syndrome 2 | 29
Brachycephaly 2 | 88
Broad cranium shape 2 | 88
Broad flat nasal bridge 2 | 236
Carcinoma, Adenoid Cystic 2 | 99
Carcinoma, Squamous Cell 2 | 110
Cognitive delay 2 | 608
Congenital Epicanthus 2 | 177
Decreased width of the skull 2 | 28
Disease Models, Animal 2 | 155
Dull intelligence 2 | 645
Dysarthria 2 | 192
Endometrial cancer 2 | 311
Fever 2 | 138
Flushing 2 | 60
Global developmental delay 2 | 608
Growth delay 2 | 114
Growth failure 2 | 114
Growth retardation 2 | 115
Hypoplastic mandible condyle 2 | 275
Intrauterine retardation 2 | 176
Low intelligence 2 | 645
Lymphadenopathy 2 | 62
Lymphoma 2 | 81
Lymphopenia 2 | 67
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Pancytopenia 2 | 45
Photosensitivity of skin 2 | 51
Pick disease 2 | 1,894
Poor growth 2 | 114
Poor school performance 2 | 645
Rheumatoid arthritis 2 | 1,191
Seckel syndrome 2 | 34
Sloping forehead 2 | 46
Squamous cell carcinoma 2 | 129
Stomach Neoplasms 2 | 300
Systemic lupus erythematosus 2 | 194
Telecanthus 2 | 62
Thin lips 2 | 49
Upward slant of palpebral fissure 2 | 75
Urinary Bladder Neoplasms 2 | 114
Very poor growth 2 | 114
Waldenstrons macroglobulinemia 2 | 765
Wide skull shape 2 | 88
Xeroderma pigmentosum group D 2 | 33
adrenocortical carcinoma 2 | 1,428
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
diabetes mellitus 2 | 1,728
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
pancreatic cancer 2 | 2,398
progressive supranuclear palsy 2 | 676

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Non-IDG 8 | 12,091
Enzyme 3 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242

Compartment GO Term

DNA ligase IV complex 14 | 14
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein PAXX PAXX Tbio Non-IDG -1.45074 28.1 33
DNA ligase 4 LIG4 Tbio Enzyme -2.14909 140.9 204
Non-homologous end-joining factor 1 NHEJ1 Tbio Non-IDG -1.93558 91.5 270
DNA repair protein XRCC1 XRCC1 Tbio Non-IDG -2.99664 1034.1 418
DNA repair protein XRCC4 XRCC4 Tbio Non-IDG -2.38352 232.9 322
X-ray repair cross-complementing protein 5 XRCC5 Tbio Non-IDG -2.68622 470.8 874
DNA-dependent protein kinase catalytic subunit PRKDC Tchem Kinase -2.85973 723.4 1160
Protein artemis DCLRE1C Tbio Non-IDG -2.27419 184.9 252
DNA ligase 3 LIG3 Tbio Enzyme -2.75144 531.1 239
Histone-lysine N-methyltransferase SETMAR SETMAR Tbio Epigenetic -1.33346 26.5 119