Development Level

Tbio 42 | 11,651
Tchem 7 | 1,388
Tdark 5 | 6,593

IMPC Phenotype

preweaning lethality, complete... 7 | 979
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 2 | 499
abnormal embryo size 1 | 220
abnormal eye morphology 1 | 68
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal spinal cord morpholog... 1 | 9
abnormal vocalization 1 | 21
decreased body weight 1 | 161
decreased circulating alanine ... 1 | 47
decreased circulating glucose ... 1 | 126
decreased fluid intake 1 | 3
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
hypoactivity 1 | 132
increased body length 1 | 32
increased body weight 1 | 25
increased circulating potassiu... 1 | 29
increased circulating sodium l... 1 | 71
increased neutrophil cell numb... 1 | 46
male infertility 1 | 123
pale yolk sac 1 | 25
small testis 1 | 58

Disease

Carcinoma 38 | 11,493
ovarian cancer 35 | 8,520
lung cancer 28 | 4,740
osteosarcoma 28 | 7,950
medulloblastoma, large-cell 26 | 6,241
psoriasis 26 | 6,694
Cancer 24 | 2,499
group 3 medulloblastoma 23 | 4,104
malignant mesothelioma 23 | 3,232
atypical teratoid / rhabdoid tumor 21 | 5,112
glioblastoma 21 | 5,792
Breast cancer 20 | 3,578
primitive neuroectodermal tumor 20 | 3,035
adult high grade glioma 18 | 3,801
lung adenocarcinoma 17 | 2,716
non-small cell lung cancer 17 | 2,890
invasive ductal carcinoma 15 | 2,951
Kidney cancer 13 | 2,613
colon cancer 13 | 1,478
Intellectual disability 12 | 1,016
Cockayne syndrome 11 | 60
Fanconi anemia 11 | 56
Rothmund-Thomson syndrome 11 | 19
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
Bloom syndrome 9 | 29
Short stature 9 | 531
Small head 9 | 374
ductal carcinoma in situ 9 | 1,745
ependymoma 9 | 4,679
Autosomal recessive predisposition 8 | 1,442
Baller-Gerold syndrome 8 | 12
Dull intelligence 8 | 645
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental deficiency 8 | 645
Poor school performance 8 | 645
Werner syndrome 8 | 29
adrenocortical carcinoma 8 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Fetal Growth Retardation 7 | 189
Infant, Small for Gestational Age 7 | 176
Intrauterine retardation 7 | 176
Multiple myeloma 7 | 1,332
Warsaw breakage syndrome 7 | 11
nasopharyngeal carcinoma 7 | 1,058
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mental and motor retardation 6 | 608
Photosensitive trichothiodystrophy 6 | 30
Waldenstrons macroglobulinemia 6 | 765
dermatomyositis 6 | 966
diabetes mellitus 6 | 1,728
Breast Neoplasms 5 | 445
Cryptorchidism 5 | 296
Mammary Neoplasms 5 | 425
Nijmegen breakage syndrome 5 | 24
Xeroderma pigmentosum group D 5 | 33
breast carcinoma 5 | 1,638
juvenile dermatomyositis 5 | 1,187
oligodendroglioma 5 | 2,850
spina bifida 5 | 1,074
Astrocytoma, Pilocytic 4 | 3,081
Ataxia telangiectasia 4 | 34
Atopic dermatitis 4 | 952
Dental caries 4 | 164
Endometriosis 4 | 540
Liver cancer 4 | 604
Macrostomia 4 | 72
Microcephaly 4 | 166
Sparse scalp hair 4 | 42
Xeroderma pigmentosum 4 | 43
acute myeloid leukemia 4 | 783
astrocytic glioma 4 | 2,597
non primary Sjogren syndrome sicca 4 | 891
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Acquired scoliosis 3 | 281
Anemia 3 | 365
Bilateral fifth finger clinodactyly 3 | 110
Congenital deafness 3 | 185
Curvature of little finger 3 | 110
Curvature of spine 3 | 282
Deafness 3 | 198
Delayed bone age 3 | 136
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Hearing Loss, Partial 3 | 185
Joint hyperflexibility 3 | 78
Large nose 3 | 23
Lung Neoplasms 3 | 232
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Recurrent respiratory infections 3 | 141
Seckel syndrome 3 | 34
Seizures 3 | 596
Strabismus 3 | 270
active Crohn's disease 3 | 922
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
hearing impairment 3 | 199

Tissue

Blood and immune system 52 | 16,909
Cardiovascular System 52 | 15,192
Digestive Tract 52 | 17,369
Endocrine System 52 | 18,159
Female tissues 52 | 17,400
Liver and Pancreas 52 | 16,750
Male tissues 52 | 17,142
Nervous System 52 | 16,725
Respiratory system 52 | 16,393
Skin and soft tissues 52 | 17,230
Urinary Tract 52 | 16,678

Target Family

Non-IDG 28 | 12,091
Enzyme 19 | 4,145
Epigenetic 3 | 242
Kinase 3 | 634
Transcription Factor 1 | 1,400

Compartment GO Term

DNA helicase complex 54 | 54
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
INO80 complex subunit B INO80B Tbio Non-IDG -1.16370 15.1 53
DNA helicase INO80 INO80 Tbio Enzyme -2.54124 327.2 47
Ubiquitin carboxyl-terminal hydrolase isozyme L5 UCHL5 Tbio Enzyme -1.71687 51.9 225
Transcriptional repressor protein YY1 YY1 Tbio Transcription Factor -2.80737 619.7 475
Twinkle protein, mitochondrial TWNK Tbio Non-IDG -2.18726 156.1 146
Crossover junction endonuclease MUS81 MUS81 Tbio Enzyme -2.06893 119.1 95
Probable global transcription activator SNF2L2 SMARCA2 Tchem Epigenetic -2.57435 345.3 153
DNA replication ATP-dependent helicase/nuclease DNA2 DNA2 Tbio Enzyme -2.42159 256.1 101
Transcription activator BRG1 SMARCA4 Tchem Epigenetic -2.86389 713.1 332
DNA repair protein RAD51 homolog 1 RAD51 Tchem Non-IDG -3.82649 6590.0 594