Development Level

Tbio 55 | 11,445
Tchem 8 | 1,598
Tdark 5 | 6,588

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to o... 4 | 239
embryonic lethality prior to t... 4 | 278
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal embryo size 2 | 220
decreased basophil cell number 2 | 16
decreased erythrocyte cell num... 2 | 62
increased fasted circulating g... 2 | 76
increased heart weight 2 | 62
small testis 2 | 58
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal femur morphology 1 | 14
abnormal locomotor behavior 1 | 24
abnormal pericardium morpholog... 1 | 26
abnormal skin condition 1 | 6
abnormal spine curvature 1 | 9
abnormal testis morphology 1 | 43
abnormal vitreous body morphol... 1 | 10
absent startle reflex 1 | 24
decreased IgE level 1 | 6
decreased blood urea nitrogen ... 1 | 51
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased eosinophil cell numb... 1 | 24
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased mean corpuscular vol... 1 | 79
decreased mean platelet volume 1 | 25
decreased neutrophil cell numb... 1 | 42
edema 1 | 59
embryonic growth retardation 1 | 106
hypoactivity 1 | 132
increased body temperature 1 | 9
increased circulating phosphat... 1 | 26
increased grip strength 1 | 41
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased mean platelet volume 1 | 45
increased prepulse inhibition 1 | 32
increased spleen weight 1 | 10
prenatal lethality 1 | 28
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 52 | 11,493
ovarian cancer 46 | 8,520
osteosarcoma 42 | 7,950
psoriasis 26 | 6,694
medulloblastoma, large-cell 25 | 6,241
lung cancer 24 | 4,740
atypical teratoid / rhabdoid tumor 23 | 5,112
Kidney cancer 22 | 2,613
Cancer 20 | 2,499
Multiple myeloma 20 | 1,332
ependymoma 20 | 4,679
glioblastoma 20 | 5,792
lung adenocarcinoma 19 | 2,716
Breast cancer 18 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
dermatomyositis 15 | 966
group 3 medulloblastoma 15 | 4,104
acute quadriplegic myopathy 14 | 1,158
invasive ductal carcinoma 14 | 2,951
oligodendroglioma 14 | 2,850
Waldenstrons macroglobulinemia 13 | 765
group 4 medulloblastoma 13 | 1,855
juvenile dermatomyositis 13 | 1,187
subependymal giant cell astrocytoma 13 | 2,287
Amyotrophic lateral sclerosis 12 | 451
astrocytic glioma 12 | 2,597
primitive neuroectodermal tumor 12 | 3,035
astrocytoma 11 | 1,146
progressive supranuclear palsy 11 | 676
Pick disease 10 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
Neurodegenerative disease 9 | 414
breast carcinoma 9 | 1,638
non-small cell lung cancer 9 | 2,890
pancreatic cancer 9 | 2,398
tuberculosis 9 | 2,010
spina bifida 8 | 1,074
Astrocytoma, Pilocytic 7 | 3,081
Schizophrenia 7 | 1,160
hepatocellular carcinoma 7 | 547
malignant mesothelioma 7 | 3,232
Anxiety 6 | 136
Anxiety disease 6 | 113
Depressive disorder 6 | 409
Nerve Degeneration 6 | 121
Rheumatoid arthritis 6 | 1,191
Spinocerebellar ataxia type 2 6 | 23
cystic fibrosis 6 | 1,696
lung carcinoma 6 | 2,843
non primary Sjogren syndrome sicca 6 | 891
pituitary cancer 6 | 1,972
primary pancreatic ductal adenocarcinoma 6 | 1,109
ulcerative colitis 6 | 1,819
Atopic dermatitis 5 | 952
Dementia 5 | 175
Dysarthria 5 | 192
Dyspnea 5 | 76
Fatigable weakness of respiratory muscles 5 | 28
Fatigable weakness of swallowing muscles 5 | 28
Fatigue 5 | 182
Frontotemporal dementia 5 | 51
Generalized muscle weakness 5 | 57
Mood swings 5 | 77
Muscle Cramp 5 | 55
Muscle Spasticity 5 | 195
Neuro-degenerative disease 5 | 43
Neurodegenerative Disorders 5 | 79
Neurogenic Muscular Atrophy 5 | 139
Neurogenic muscle atrophy, especially in the lower limbs 5 | 139
Pain 5 | 103
Paralysed 5 | 42
Respiratory Failure 5 | 104
Skeletal muscle atrophy 5 | 139
Xerostomia 5 | 42
colon cancer 5 | 1,478
diabetes mellitus 5 | 1,728
ductal carcinoma in situ 5 | 1,745
muscle degeneration 5 | 139
Alzheimer's disease 4 | 658
Down syndrome 4 | 499
Duchenne muscular dystrophy 4 | 601
Fragile X syndrome 4 | 34
Gaucher disease type 1 4 | 180
Intellectual disability 4 | 1,016
Myopathy 4 | 185
Parkinson's disease 4 | 392
Primary biliary cirrhosis 4 | 51
acute myeloid leukemia 4 | 783
adrenocortical carcinoma 4 | 1,428
aldosterone-producing adenoma 4 | 665
atypical teratoid/rhabdoid tumor 4 | 357
cutaneous lupus erythematosus 4 | 1,057
hereditary spastic paraplegia 4 | 318
nasopharyngeal carcinoma 4 | 1,058
primary Sjogren syndrome 4 | 735
relapsing-remitting multiple sclerosis 4 | 18
gastric carcinoma 3 | 807

Tissue

Blood and immune system 68 | 16,909
Digestive Tract 68 | 17,369
Endocrine System 68 | 18,159
Female tissues 68 | 17,400
Liver and Pancreas 68 | 16,750
Respiratory system 68 | 16,393
Male tissues 67 | 17,142
Nervous System 67 | 16,725
Skin and soft tissues 67 | 17,230
Urinary Tract 67 | 16,678
Cardiovascular System 66 | 15,192

Target Family

Non-IDG 52 | 12,091
Enzyme 11 | 4,145
Epigenetic 2 | 242
Transcription Factor 2 | 1,400
Kinase 1 | 634

Compartment GO Term

Cytoplasmic stress granule 68 | 68
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein LSM14 homolog A LSM14A Tbio Non-IDG -1.13869 16.0 122
Roquin-1 RC3H1 Tbio Non-IDG -1.59779 44.7 106
Ataxin-2-like protein ATXN2L Tbio Non-IDG -1.58925 37.9 93
Dual specificity tyrosine-phosphorylation-regulated kinase 3 DYRK3 Tchem Kinase -1.46121 29.1 191
5'-3' exoribonuclease 1 XRN1 Tbio Enzyme -2.13482 125.3 51
Nanos homolog 3 NANOS3 Tbio Non-IDG -1.60288 41.2 90
Enhancer of mRNA-decapping protein 4 EDC4 Tbio Non-IDG -2.26552 178.5 97
Insulin-like growth factor 2 mRNA-binding protein 1 IGF2BP1 Tbio Non-IDG -1.85997 76.0 207
Fragile X mental retardation syndrome-related protein 1 FXR1 Tbio Non-IDG -1.70770 50.9 220
GRB10-interacting GYF protein 2 GIGYF2 Tchem Non-IDG -1.52965 37.1 43