Development Level

Tbio 148 | 11,445
Tchem 46 | 1,598
Tclin 17 | 613
Tdark 6 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99
RFA-RM-18-021 3 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 19 | 979
preweaning lethality, incomple... 11 | 499
abnormal bone structure 10 | 187
increased startle reflex 10 | 112
abnormal behavior 7 | 298
decreased bone mineral content 5 | 151
decreased total body fat amoun... 5 | 207
hypoactivity 5 | 132
abnormal seminal vesicle morph... 4 | 114
decreased body weight 4 | 161
decreased lymphocyte cell numb... 4 | 83
increased heart weight 4 | 62
increased monocyte cell number 4 | 63
abnormal retina morphology 3 | 71
decreased bone mineral density 3 | 126
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating alanine ... 3 | 47
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
increased neutrophil cell numb... 3 | 46
increased total body fat amoun... 3 | 134
short tibia 3 | 97
thrombocytopenia 3 | 56
abnormal embryo size 2 | 220
abnormal gait 2 | 69
abnormal sleep behavior 2 | 70
decreased body length 2 | 101
decreased circulating choleste... 2 | 93
decreased circulating phosphat... 2 | 27
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased lean body mass 2 | 135
decreased mean corpuscular hem... 2 | 50
decreased prepulse inhibition 2 | 82
embryonic lethality prior to o... 2 | 239
hyperactivity 2 | 148
impaired righting response 2 | 26
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating phosphat... 2 | 26
increased circulating potassiu... 2 | 29
increased hematocrit 2 | 46
increased mean corpuscular vol... 2 | 92
increased spleen weight 2 | 10
prenatal lethality prior to he... 2 | 87
prolonged QT interval 2 | 38
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal hair growth 1 | 10
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vertebrae morphology 1 | 18
abnormal vocalization 1 | 21
absent pinna reflex 1 | 23
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
hemorrhage 1 | 23
hydrometra 1 | 53
impaired pupillary reflex 1 | 26
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
persistence of hyaloid vascula... 1 | 33
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74
small testis 1 | 58
tremors 1 | 39
vertebral fusion 1 | 23

Disease

Carcinoma 160 | 11,493
osteosarcoma 126 | 7,950
ovarian cancer 121 | 8,520
medulloblastoma, large-cell 95 | 6,241
glioblastoma 89 | 5,792
psoriasis 80 | 6,694
Cancer 76 | 2,499
atypical teratoid / rhabdoid tumor 76 | 5,112
ependymoma 70 | 4,679
lung cancer 70 | 4,740
Breast cancer 60 | 3,578
adult high grade glioma 60 | 3,801
group 3 medulloblastoma 59 | 4,104
Astrocytoma, Pilocytic 57 | 3,081
oligodendroglioma 54 | 2,850
Kidney cancer 53 | 2,613
invasive ductal carcinoma 51 | 2,951
lung carcinoma 49 | 2,843
primitive neuroectodermal tumor 46 | 3,035
subependymal giant cell astrocytoma 46 | 2,287
malignant mesothelioma 45 | 3,232
non-small cell lung cancer 45 | 2,890
pancreatic cancer 45 | 2,398
interstitial cystitis 41 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 40 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 39 | 3,291
Pick disease 38 | 1,894
astrocytic glioma 38 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 37 | 2,955
lung adenocarcinoma 37 | 2,716
tuberculosis 37 | 2,010
ulcerative colitis 36 | 1,819
pituitary cancer 33 | 1,972
juvenile dermatomyositis 31 | 1,187
breast carcinoma 29 | 1,638
group 4 medulloblastoma 29 | 1,855
diabetes mellitus 27 | 1,728
Schizophrenia 26 | 1,160
colon cancer 26 | 1,478
ductal carcinoma in situ 25 | 1,745
Rheumatoid arthritis 24 | 1,191
Autosomal recessive predisposition 22 | 1,442
Intellectual disability 21 | 1,016
Liver Cirrhosis, Experimental 21 | 769
acute quadriplegic myopathy 21 | 1,158
Obesity 20 | 678
astrocytoma 20 | 1,146
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
primary Sjogren syndrome 20 | 735
cutaneous lupus erythematosus 19 | 1,057
cystic fibrosis 19 | 1,696
Blastic phase chronic myeloid leukemia 18 | 58
Chronic Myelocytic Leukemia Accelerated Phase 18 | 59
Melanoma 18 | 711
Multiple myeloma 18 | 1,332
spina bifida 18 | 1,074
Epilepsy 17 | 792
Chronic phase chronic myeloid leukemia 16 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 16 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 16 | 47
dermatomyositis 16 | 966
pediatric high grade glioma 16 | 1,064
primary pancreatic ductal adenocarcinoma 16 | 1,109
Alzheimer's disease 15 | 658
Hypertension 15 | 396
adrenocortical carcinoma 15 | 1,428
Bipolar Disorder 14 | 666
Liver cancer 14 | 604
Skin cancer 14 | 469
Atopic dermatitis 13 | 952
Duchenne muscular dystrophy 13 | 601
Kidney disease 13 | 430
Stomach Neoplasms 13 | 300
esophageal adenocarcinoma 13 | 737
non primary Sjogren syndrome sicca 13 | 891
Crohn's disease 12 | 321
Depressive disorder 12 | 409
Dull intelligence 12 | 645
Low intelligence 12 | 645
Mental Retardation 12 | 645
Mental deficiency 12 | 645
Poor school performance 12 | 645
pancreatic carcinoma 12 | 562
Chronic Lymphocytic Leukemia 11 | 262
Down syndrome 11 | 499
Polycystic ovary syndrome 11 | 360
Prostatic Neoplasms 11 | 495
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
mucosa-associated lymphoid tissue lymphoma 11 | 484
Anemia 10 | 365
Asthma 10 | 385
Cognitive delay 10 | 608
Endometrial cancer 10 | 311
Endometriosis 10 | 540
Fatigue 10 | 182
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Parkinson's disease 10 | 392
Immune system cancer 9 | 140
Short stature 9 | 531

Tissue

Endocrine System 211 | 18,159
Blood and immune system 207 | 16,909
Skin and soft tissues 207 | 17,230
Digestive Tract 206 | 17,369
Female tissues 206 | 17,400
Male tissues 204 | 17,142
Nervous System 204 | 16,725
Liver and Pancreas 203 | 16,750
Urinary Tract 202 | 16,678
Respiratory system 199 | 16,393
Cardiovascular System 195 | 15,192

Target Family

Non-IDG 124 | 12,091
Enzyme 42 | 4,145
Kinase 41 | 634
Ion Channel 5 | 344
GPCR 3 | 408
Transcription Factor 2 | 1,400

Compartment GO Term

Cytoplasmic side of membrane 217 | 217
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adherens junction-associated protein 1 AJAP1 Tbio Non-IDG -1.20907 21.2 25
Myocardial zonula adherens protein POLR2M Tbio Non-IDG -1.87592 70.6 20
Sorting nexin-5 SNX5 Tbio Non-IDG -1.23706 20.8 141
Ras-related protein Rab-21 RAB21 Tbio Enzyme -1.33715 23.1 275
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Tyrosine-protein phosphatase non-receptor type 3 PTPN3 Tbio Enzyme -1.40961 29.1 162
Ras/Rap GTPase-activating protein SynGAP SYNGAP1 Tbio Enzyme -1.91757 81.2 178
Ras GTPase-activating protein nGAP RASAL2 Tbio Enzyme -1.51440 33.0 99
Rho guanine nucleotide exchange factor 25 ARHGEF25 Tbio Non-IDG -1.43926 31.5 50
Guanine nucleotide-binding protein subunit alpha-11 GNA11 Tbio Non-IDG -2.80484 555.1 184