Development Level

Tbio 177 | 11,445
Tchem 29 | 1,598
Tdark 12 | 6,588
Tclin 10 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99
RFA-RM-18-021 2 | 328
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 24 | 979
preweaning lethality, incomple... 15 | 499
decreased body weight 10 | 161
abnormal embryo size 7 | 220
increased lean body mass 7 | 172
embryonic lethality prior to o... 6 | 239
embryonic lethality prior to t... 6 | 278
abnormal behavior 5 | 298
abnormal bone structure 5 | 187
decreased caudal vertebrae num... 5 | 53
increased total body fat amoun... 5 | 134
short tibia 5 | 97
abnormal retina morphology 4 | 71
decreased bone mineral content 4 | 151
decreased circulating LDL chol... 4 | 38
decreased total body fat amoun... 4 | 207
decreased vertical activity 4 | 208
enlarged heart 4 | 210
hypoactivity 4 | 132
impaired glucose tolerance 4 | 75
increased bone mineral content 4 | 108
increased circulating alkaline... 4 | 122
abnormal bone mineralization 3 | 38
abnormal coat appearance 3 | 31
abnormal embryo turning 3 | 31
abnormal locomotor activation 3 | 16
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased circulating creatini... 3 | 39
decreased circulating serum al... 3 | 82
decreased mean corpuscular vol... 3 | 79
embryonic growth retardation 3 | 106
increased circulating chloride... 3 | 41
increased circulating choleste... 3 | 66
increased circulating sodium l... 3 | 71
persistence of hyaloid vascula... 3 | 33
prolonged QT interval 3 | 38
prolonged ST segment 3 | 36
tremors 3 | 39
abnormal cornea morphology 2 | 31
abnormal cranium morphology 2 | 36
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
cardiovascular system phenotyp... 2 | 36
cataract 2 | 92
corneal opacity 2 | 32
decreased circulating alanine ... 2 | 47
decreased circulating amylase ... 2 | 28
decreased circulating calcium ... 2 | 36
decreased circulating total pr... 2 | 49
decreased circulating triglyce... 2 | 79
decreased fasted circulating g... 2 | 65
decreased grip strength 2 | 116
decreased lymphocyte cell numb... 2 | 83
decreased red blood cell distr... 2 | 41
edema 2 | 59
enlarged kidney 2 | 14
enlarged uterus 2 | 11
fused cornea and lens 2 | 5
hemorrhage 2 | 23
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased bone mineral density 2 | 72
increased circulating HDL chol... 2 | 80
increased circulating calcium ... 2 | 34
increased circulating creatini... 2 | 38
increased leukocyte cell numbe... 2 | 47
increased mean platelet volume 2 | 45
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
increased startle reflex 2 | 112
increased vertical activity 2 | 24
limb grasping 2 | 41
pallor 2 | 34
prenatal lethality prior to he... 2 | 87
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal ear morphology 1 | 9
abnormal head morphology 1 | 10
abnormal optic disc morphology 1 | 10
abnormal retinal inner nuclear... 1 | 8
abnormal spleen morphology 1 | 55
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal whole-body plethysmog... 1 | 4
decreased body length 1 | 101
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased total retina thickne... 1 | 17
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased circulating amylase ... 1 | 25
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
microphthalmia 1 | 26
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 188 | 11,493
ovarian cancer 133 | 8,520
osteosarcoma 130 | 7,950
medulloblastoma, large-cell 116 | 6,241
glioblastoma 112 | 5,792
psoriasis 105 | 6,694
atypical teratoid / rhabdoid tumor 101 | 5,112
ependymoma 96 | 4,679
adult high grade glioma 80 | 3,801
lung cancer 77 | 4,740
group 3 medulloblastoma 75 | 4,104
Kidney cancer 74 | 2,613
Astrocytoma, Pilocytic 73 | 3,081
oligodendroglioma 71 | 2,850
primitive neuroectodermal tumor 69 | 3,035
Breast cancer 65 | 3,578
Cancer 64 | 2,499
pancreatic cancer 63 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 62 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 60 | 2,989
subependymal giant cell astrocytoma 59 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 58 | 2,955
invasive ductal carcinoma 57 | 2,951
astrocytic glioma 56 | 2,597
lung carcinoma 52 | 2,843
lung adenocarcinoma 51 | 2,716
non-small cell lung cancer 51 | 2,890
malignant mesothelioma 47 | 3,232
interstitial cystitis 44 | 2,312
Pick disease 42 | 1,894
ductal carcinoma in situ 42 | 1,745
breast carcinoma 41 | 1,638
pituitary cancer 37 | 1,972
diabetes mellitus 36 | 1,728
tuberculosis 35 | 2,010
Schizophrenia 34 | 1,160
primary pancreatic ductal adenocarcinoma 34 | 1,109
colon cancer 31 | 1,478
ulcerative colitis 31 | 1,819
group 4 medulloblastoma 30 | 1,855
acute quadriplegic myopathy 29 | 1,158
adrenocortical carcinoma 28 | 1,428
Autosomal recessive predisposition 27 | 1,442
juvenile dermatomyositis 27 | 1,187
Down syndrome 26 | 499
Intellectual disability 26 | 1,016
Liver cancer 26 | 604
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
Duchenne muscular dystrophy 24 | 601
cystic fibrosis 24 | 1,696
Melanoma 23 | 711
astrocytoma 23 | 1,146
progressive supranuclear palsy 23 | 676
Rheumatoid arthritis 22 | 1,191
Alzheimer's disease 21 | 658
dermatomyositis 21 | 966
Bipolar Disorder 20 | 666
Epilepsy 20 | 792
autosomal dominant Emery-Dreifuss muscular dystrophy 20 | 510
spina bifida 20 | 1,074
Skin cancer 19 | 469
Multiple myeloma 18 | 1,332
gastric carcinoma 18 | 807
Waldenstrons macroglobulinemia 17 | 765
esophageal adenocarcinoma 17 | 737
Amyotrophic lateral sclerosis 16 | 451
Atopic dermatitis 16 | 952
Hypertension 16 | 396
Liver Cirrhosis, Experimental 16 | 769
Neurodegenerative disease 16 | 414
cutaneous lupus erythematosus 16 | 1,057
Cognitive delay 15 | 608
Dull intelligence 15 | 645
Endometrial cancer 15 | 311
Global developmental delay 15 | 608
Low intelligence 15 | 645
Mental Retardation 15 | 645
Mental and motor retardation 15 | 608
Mental deficiency 15 | 645
Poor school performance 15 | 645
Seizures 15 | 596
medulloblastoma 15 | 720
non primary Sjogren syndrome sicca 15 | 891
pediatric high grade glioma 15 | 1,064
Depressive disorder 14 | 409
Osteoporosis 14 | 363
active ulcerative colitis 14 | 764
acute myeloid leukemia 14 | 783
nasopharyngeal carcinoma 14 | 1,058
Breast Neoplasms 12 | 445
Gaucher disease type 1 12 | 180
Heart disease 12 | 306
Mental Depression 12 | 333
Muscle hypotonia 12 | 571
Vascular disease 12 | 319
fibroadenoma 12 | 559
pancreatic carcinoma 12 | 562
Infantile onset 11 | 238
Neuropathy 11 | 261
Short stature 11 | 531

Tissue

Endocrine System 225 | 18,159
Skin and soft tissues 224 | 17,230
Female tissues 223 | 17,400
Digestive Tract 222 | 17,369
Blood and immune system 221 | 16,909
Liver and Pancreas 220 | 16,750
Nervous System 218 | 16,725
Respiratory system 218 | 16,393
Urinary Tract 218 | 16,678
Male tissues 217 | 17,142
Cardiovascular System 209 | 15,192

Target Family

Non-IDG 169 | 12,091
Enzyme 33 | 4,145
Kinase 13 | 634
Ion Channel 7 | 344
GPCR 3 | 408
Transporter 2 | 473
Epigenetic 1 | 242

Compartment GO Term

Cytoplasmic region 228 | 228
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Septin-11 SEPT11 Tbio Non-IDG -1.47747 32.4 127
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
Metabotropic glutamate receptor 7 GRM7 Tchem GPCR -2.25415 190.8 304
Myocardial zonula adherens protein POLR2M Tbio Non-IDG -1.87592 70.6 20
Protein spire homolog 2 SPIRE2 Tbio Non-IDG -0.76971 5.22 91
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Trichoplein keratin filament-binding protein TCHP Tbio Non-IDG -2.34455 143.0 113
A-kinase anchor protein 12 AKAP12 Tbio Enzyme -2.00948 126.8 160
Muskelin MKLN1 Tbio Non-IDG -1.08451 14.7 102