Development Level

Tbio 44 | 11,651
Tdark 11 | 6,593
Tclin 7 | 612
Tchem 4 | 1,388

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to o... 5 | 239
abnormal embryo size 4 | 220
embryonic lethality prior to t... 4 | 278
pallor 4 | 34
abnormal placenta size 2 | 20
abnormal skin coloration 2 | 25
decreased circulating chloride... 2 | 30
decreased vertical activity 2 | 208
prenatal lethality prior to he... 2 | 87
abnormal digit morphology 1 | 10
abnormal embryonic autopod pla... 1 | 2
abnormal hindbrain development 1 | 16
abnormal lens morphology 1 | 81
abnormal limb bud morphology 1 | 17
abnormal liver size 1 | 5
abnormal lung morphology 1 | 26
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal placenta development 1 | 1
abnormal placenta morphology 1 | 5
abnormal sensory capabilities-... 1 | 8
abnormal stomach morphology 1 | 10
cataract 1 | 92
decreased circulating LDL chol... 1 | 38
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
embryonic growth retardation 1 | 106
enlarged heart atrium 1 | 4
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating glucose ... 1 | 24
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
pale liver 1 | 6
prenatal lethality 1 | 28
small adrenal glands 1 | 16
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56

Disease

ovarian cancer 29 | 8,519
osteosarcoma 25 | 7,950
Carcinoma 23 | 11,493
psoriasis 22 | 6,694
Leigh disease 17 | 100
Acidosis, Lactic 16 | 97
Cerebellar Ataxia 16 | 304
Increased serum lactate 16 | 60
Lactic acidemia 16 | 95
Multiple myeloma 16 | 1,332
diabetes mellitus 16 | 1,728
lung cancer 15 | 4,740
medulloblastoma, large-cell 15 | 6,241
Autosomal recessive predisposition 14 | 1,442
cytochrome-c oxidase deficiency disease 14 | 19
Blepharoptosis 13 | 231
Lactic acidosis 13 | 51
Optic Atrophy 13 | 242
pancreatic ductal adenocarcinoma liver metastasis 13 | 1,962
Cytochrome-c Oxidase Deficiency 12 | 17
Dystonia 12 | 164
Dystonic disease 12 | 106
Sensorineural Hearing Loss (disorder) 12 | 284
astrocytic glioma 12 | 2,597
glioblastoma 12 | 5,792
Myopathy 11 | 185
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
Cognitive delay 10 | 608
Global developmental delay 10 | 608
Mental and motor retardation 10 | 608
Obesity 10 | 678
Ophthalmoplegia 10 | 106
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,290
Dementia 9 | 175
Depressive disorder 9 | 409
Heart failure 9 | 162
Leigh syndrome 9 | 28
Neuropathy 9 | 261
Ragged-red fibers 9 | 21
Anxiety 8 | 136
Anxiety disease 8 | 113
Brain Ischemia 8 | 110
Breast cancer 8 | 3,577
Cerebral atrophy 8 | 178
Epilepsy 8 | 792
Hallucinations 8 | 34
Hallucinations, Sensory 8 | 33
Mitochondrial Myopathies 8 | 21
Muscle Weakness 8 | 170
Muscle hypotonia 8 | 571
adult high grade glioma 8 | 3,801
group 3 medulloblastoma 8 | 4,104
oligodendroglioma 8 | 2,850
Anemia 7 | 365
Blind spot located at fixation point 7 | 21
Blurred vision 7 | 19
CSF lactate increased 7 | 33
Cancer 7 | 2,499
Death in early adulthood 7 | 24
Decreased visual acuity, slowly progressive 7 | 13
Diabetes Mellitus, Non-Insulin-Dependent 7 | 145
Dull intelligence 7 | 645
Encephalopathies 7 | 43
Fatigue 7 | 182
Hemianopsia 7 | 15
Highly variable severity 7 | 157
Hypertrophic Cardiomyopathy 7 | 117
Intellectual disability 7 | 1,016
Intermittent migraine headaches 7 | 68
Leber hereditary optic neuropathy 7 | 14
Low intelligence 7 | 645
MELAS syndrome 7 | 18
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Migraine Disorders 7 | 76
Mitochondrial Complex III Deficiency 7 | 9
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes 7 | 9
Mitochondrial respiratory chain defects 7 | 15
Nystagmus 7 | 317
Optic Atrophy, Hereditary, Leber 7 | 14
Poor school performance 7 | 645
Retinal telangiectasia 7 | 12
Retinitis Pigmentosa 7 | 226
Schizophrenia 7 | 1,160
Scotoma, Central 7 | 21
Scotoma, Centrocecal 7 | 11
Seizures 7 | 596
Short stature 7 | 531
Slow decrease in visual acuity 7 | 13
Tonic - clonic seizures 7 | 44
Tortuous retinal vessels 7 | 15
Variable expressivity 7 | 157
Wolff-Parkinson-White syndrome 7 | 19
lung adenocarcinoma 7 | 2,716
Developmental regression 6 | 95
Loss of developmental milestones 6 | 95
Psychomotor regression 6 | 95
Psychomotor regression in infants 6 | 95
Psychomotor regression, progressive 6 | 95

Tissue

Endocrine System 64 | 18,159
Blood and immune system 63 | 16,909
Digestive Tract 63 | 17,369
Female tissues 63 | 17,400
Male tissues 63 | 17,142
Skin and soft tissues 63 | 17,230
Urinary Tract 63 | 16,678
Liver and Pancreas 62 | 16,750
Nervous System 62 | 16,725
Cardiovascular System 61 | 15,192
Respiratory system 60 | 16,393

Target Family

Enzyme 39 | 4,145
Non-IDG 21 | 12,091
Transporter 3 | 473
Transcription Factor 2 | 1,400
Kinase 1 | 634

Compartment GO Term

Cytochrome complex 66 | 66
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cytochrome b-c1 complex subunit 6-like, mitochondrial UQCRHL Tdark Non-IDG -0.84371 11.5 0
Cytochrome c oxidase subunit 7A2, mitochondrial COX7A2 Tdark Enzyme -0.95678 16.5 0
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial COA3 Tbio Enzyme -0.93118 9.16 38
Potassium-transporting ATPase alpha chain 2 ATP12A Tchem Transporter -3.82877 6449.5 90
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 Tbio Enzyme -2.34320 203.3 504
Cytochrome c oxidase subunit 6B1 COX6B1 Tbio Enzyme -1.29185 18.7 218
NADH-ubiquinone oxidoreductase chain 5 MT-ND5 Tclin Enzyme -2.74433 526.0 175
Cytochrome c oxidase subunit 6A1, mitochondrial COX6A1 Tbio Enzyme -1.06552 12.3 194
NADH-ubiquinone oxidoreductase chain 1 MT-ND1 Tclin Enzyme -2.63554 400.3 136
Cytochrome b-c1 complex subunit 7 UQCRB Tbio Non-IDG -1.29421 22.8 112