Development Level

Tbio 4 | 11,445
Tchem 4 | 1,598
Tclin 2 | 613

IMPC Phenotype

abnormal lens morphology 2 | 81
cataract 2 | 92
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased circulating insulin ... 1 | 76
edema 1 | 59
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged heart atrium 1 | 4
enlarged spleen 1 | 41
female infertility 1 | 60
hyperactivity 1 | 148
male infertility 1 | 123
microphthalmia 1 | 26
preweaning lethality, incomple... 1 | 499
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Cancer 10 | 2,499
Carcinoma 8 | 11,493
lung cancer 8 | 4,740
medulloblastoma, large-cell 8 | 6,241
ovarian cancer 8 | 8,520
glioblastoma 7 | 5,792
malignant mesothelioma 7 | 3,232
osteosarcoma 7 | 7,950
atypical teratoid / rhabdoid tumor 6 | 5,112
primitive neuroectodermal tumor 6 | 3,035
psoriasis 6 | 6,694
Adenoma 5 | 167
Astrocytoma, Pilocytic 5 | 3,081
Breast cancer 5 | 3,578
Carcinoma, Hepatocellular 5 | 228
Liver carcinoma 5 | 240
Lung Neoplasms 5 | 232
Stomach Neoplasms 5 | 300
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
Breast Neoplasms 4 | 445
Esophageal Squamous Cell Carcinoma 4 | 77
Immune system cancer 4 | 140
Lymphoid leukemia 4 | 160
Mammary Neoplasms 4 | 425
Mammary Neoplasms, Experimental 4 | 154
Melanoma 4 | 711
Papilloma 4 | 44
Squamous cell carcinoma of esophagus 4 | 77
Stomach cancer 4 | 30
astrocytoma 4 | 1,146
group 3 medulloblastoma 4 | 4,104
lung adenocarcinoma 4 | 2,716
oligodendroglioma 4 | 2,850
Animal Mammary Neoplasms 3 | 136
Bladder Neoplasm 3 | 112
Brain Neoplasms 3 | 33
Brain Stem Neoplasms 3 | 4
DOID:2627 3 | 94
Hormone receptor positive malignant neoplasm of breast 3 | 10
Human epidermal growth factor 2 negative carcinoma of breast 3 | 3
Hyperparathyroidism 3 | 48
Kidney cancer 3 | 2,613
Liver neoplasms 3 | 130
Lymphoma 3 | 81
Mammary Neoplasms, Animal 3 | 136
Mesothelioma, Malignant 3 | 105
Multiple myeloma 3 | 1,332
Myeloma, Multiple 3 | 6
Neoplasms, Experimental 3 | 40
Parathyroid Adenoma 3 | 19
Precursor Cell Lymphoblastic Leukemia Lymphoma 3 | 43
Precursor Cell Lymphoblastic Leukemia-Lymphoma 3 | 49
Prostatic Neoplasms 3 | 495
Sezary Syndrome 3 | 27
Urinary Bladder Neoplasms 3 | 114
Vascular disease 3 | 319
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
familial melanoma 3 | 10
nasopharyngeal carcinoma 3 | 1,058
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Abnormality of the lymphatic system 2 | 14
Adenocarcinoma 2 | 122
Adrenal cortical adenoma 2 | 19
Barrett's esophagus 2 | 182
CMM1 2 | 5
Carcinoma, Non-Small-Cell Lung 2 | 107
Carcinoma, Squamous Cell 2 | 110
Carcinoma, Transitional Cell 2 | 32
Diarrhea 2 | 253
Dry skin 2 | 75
Dysplastic nevus syndrome 2 | 7
ENSP00000256078 2 | 30
Esophageal Neoplasms 2 | 69
Freckles 2 | 33
Hair shaft abnormalities 2 | 30
Head and neck squamous cell carcinoma 2 | 11
Hereditary Melanoma 2 | 12
Hypercalcemia 2 | 59
Intestinal Neoplasms 2 | 12
Kidney Diseases 2 | 114
Kidney Neoplasm 2 | 29
Kidney Neoplasms 2 | 37
Liver cancer 2 | 604
Lymphatic Diseases 2 | 14
MELANOMA, CUTANEOUS MALIGNANT, 1 2 | 13
Melanocytic nevus 2 | 43
Mesothelioma 2 | 38
Nevus 2 | 19
Precancerous Conditions 2 | 80
Primary cutaneous T-cell lymphoma 2 | 29
Squamous cell carcinoma 2 | 129
Wolf-Hirschhorn syndrome 2 | 32
Xerosis 2 | 75
hair abnormalities (non-specific) 2 | 30
non-small cell lung carcinoma 2 | 317

Tissue

Blood and immune system 9 | 16,909
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 4 | 12,091
Enzyme 3 | 4,145
Kinase 3 | 634

Compartment GO Term

Cyclin D1-CDK4 complex 10 | 10
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150
Cyclin-dependent kinase inhibitor 2A CDKN2A Tbio Enzyme -3.72848 9058.6 1063
Cyclin-dependent kinase 6 CDK6 Tclin Kinase -2.71197 390.1 730
G1/S-specific cyclin-D1 CCND1 Tchem Non-IDG -3.82232 5737.3 1312
Cyclin-dependent kinase inhibitor 1 CDKN1A Tbio Enzyme -3.43737 3042.8 1509
Cyclin-dependent kinase 2 CDK2 Tchem Kinase -3.44266 2522.8 1114
Cyclin-dependent kinase 4 CDK4 Tclin Kinase -3.24878 1546.3 803
Tumor suppressor ARF CDKN2A Tbio Non-IDG -3.72848 9058.6 1063
Cyclin-dependent kinase inhibitor 1B CDKN1B Tbio Enzyme -3.11753 1246.6 1886
G1/S-specific cyclin-D3 CCND3 Tchem Non-IDG -2.54253 308.4 607