Development Level

Tbio 39 | 11,178
Tchem 7 | 1,885
Tdark 6 | 6,569
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
decreased basophil cell number 2 | 16
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased circulating chloride... 1 | 41
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
thrombocytopenia 1 | 56

Disease

Carcinoma 36 | 11,192
ovarian cancer 32 | 8,297
osteosarcoma 26 | 7,766
glioblastoma 23 | 5,635
medulloblastoma, large-cell 23 | 6,086
psoriasis 22 | 6,514
group 3 medulloblastoma 21 | 4,002
atypical teratoid / rhabdoid tumor 20 | 4,971
ependymoma 20 | 4,559
oligodendroglioma 19 | 2,768
Breast cancer 18 | 3,469
Cancer 17 | 2,388
lung cancer 17 | 4,607
malignant mesothelioma 16 | 3,135
primitive neuroectodermal tumor 16 | 2,957
pituitary cancer 15 | 1,915
subependymal giant cell astrocytoma 14 | 2,230
Astrocytoma, Pilocytic 13 | 3,006
Schizophrenia 13 | 1,136
adult high grade glioma 13 | 3,701
Intellectual disability 12 | 998
astrocytic glioma 12 | 2,530
Epilepsy 11 | 775
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,872
invasive ductal carcinoma 11 | 2,867
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,204
diabetes mellitus 9 | 1,683
interstitial cystitis 9 | 2,237
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,902
Alzheimer's disease 8 | 640
Multiple Sclerosis 8 | 527
Muscle hypotonia 8 | 562
Seizures 8 | 584
lung adenocarcinoma 8 | 2,627
non-small cell lung cancer 8 | 2,799
Cryptorchidism 7 | 287
Dull intelligence 7 | 634
Kidney cancer 7 | 2,548
Low intelligence 7 | 634
Mental Retardation 7 | 634
Mental deficiency 7 | 634
Poor school performance 7 | 634
Small head 7 | 366
astrocytoma 7 | 1,113
colon cancer 7 | 1,428
group 4 medulloblastoma 7 | 1,806
Autosomal recessive predisposition 6 | 1,407
Bipolar Disorder 6 | 646
Cerebrovascular disease 6 | 223
Lissencephaly 6 | 69
Multiple myeloma 6 | 1,296
Parkinson's disease 6 | 378
Pick disease 6 | 1,856
Rheumatoid arthritis 6 | 1,156
breast carcinoma 6 | 1,589
ductal carcinoma in situ 6 | 1,686
lung carcinoma 6 | 2,755
pancreatic cancer 6 | 2,322
tuberculosis 6 | 1,963
Amyotrophic lateral sclerosis 5 | 437
Brain Ischemia 5 | 107
Cerebellar Ataxia 5 | 302
Cockayne syndrome 5 | 59
Down syndrome 5 | 480
Mental Depression 5 | 325
Microcephaly 5 | 166
Short stature 5 | 514
acute quadriplegic myopathy 5 | 1,133
juvenile dermatomyositis 5 | 1,147
pediatric high grade glioma 5 | 1,035
Atopic dermatitis 4 | 915
Autistic Disorder 4 | 358
Blepharoptosis 4 | 229
Cataract 4 | 290
Dementia 4 | 172
Depressive disorder 4 | 401
Downward slant of palpebral fissure 4 | 158
Glaucoma 4 | 232
Hypogonadism 4 | 169
Hypoplastic mandible condyle 4 | 273
Lens Opacities 4 | 227
Liver cancer 4 | 589
Major Depressive Disorder 4 | 293
Mandibular hypoplasia 4 | 273
Melanoma 4 | 689
Micrognathism 4 | 273
Nystagmus 4 | 309
Periventricular nodular heterotopia 4 | 30
Stomach Neoplasms 4 | 287
Strabismus 4 | 265
Toxic encephalopathy 4 | 139
Unipolar Depression 4 | 244
adrenocortical carcinoma 4 | 1,385
cutaneous lupus erythematosus 4 | 1,016
hepatocellular carcinoma 4 | 536
limb girdle muscular dystrophy 2A 4 | 208
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,911
ulcerative colitis 4 | 1,765
gastric cancer 3 | 445
primary Sjogren syndrome 3 | 710

Tissue

Digestive Tract 53 | 17,369
Endocrine System 52 | 18,159
Nervous System 52 | 16,725
Skin and soft tissues 52 | 17,230
Blood and immune system 51 | 16,909
Female tissues 51 | 17,400
Urinary Tract 51 | 16,678
Liver and Pancreas 50 | 16,750
Male tissues 50 | 17,142
Respiratory system 49 | 16,393
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 40 | 12,091
Transcription Factor 6 | 1,400
Enzyme 4 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242

Compartment GO Term

Cul4-RING E3 ubiquitin ligase ... 53 | 53
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA damage-binding protein 1 DDB1 Tchem Non-IDG -2.34719 202.5 353
Allograft inflammatory factor 1 AIF1 Tbio Non-IDG -3.07876 1105.3 601
N-lysine methyltransferase KMT5A KMT5A Tchem Epigenetic -1.89071 71.7 420
Paired mesoderm homeobox protein 2B PHOX2B Tbio Transcription Factor -2.49193 315.4 127
Serine/threonine-protein kinase DCLK2 DCLK2 Tchem Kinase -0.89222 8.01 148
Reelin RELN Tbio Non-IDG -2.78255 645.2 121
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.23341 1462.9 208
Oligodendrocyte transcription factor 2 OLIG2 Tbio Transcription Factor -2.64017 420.5 368
DDB1- and CUL4-associated factor 1 DCAF1 Tbio Non-IDG -1.71452 57.7 62
DDB1- and CUL4-associated factor 13 DCAF13 Tbio Non-IDG -0.63403 3.77 86