Development Level

Tbio 43 | 11,651
Tdark 6 | 6,593
Tchem 4 | 1,388
Tclin 1 | 612

IMPC Phenotype

preweaning lethality, complete... 3 | 979
preweaning lethality, incomple... 3 | 499
decreased basophil cell number 2 | 16
abnormal anxiety-related respo... 1 | 1
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal heart morphology 1 | 162
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal social-conspecific in... 1 | 3
cardiovascular system phenotyp... 1 | 36
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased heart rate variabili... 1 | 13
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased circulating chloride... 1 | 41
increased circulating total pr... 1 | 28
increased exploration in new e... 1 | 8
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
thrombocytopenia 1 | 56

Disease

Carcinoma 37 | 11,493
ovarian cancer 32 | 8,520
osteosarcoma 26 | 7,950
glioblastoma 24 | 5,792
medulloblastoma, large-cell 24 | 6,241
group 3 medulloblastoma 22 | 4,104
psoriasis 22 | 6,694
atypical teratoid / rhabdoid tumor 21 | 5,112
ependymoma 21 | 4,679
oligodendroglioma 20 | 2,850
Breast cancer 18 | 3,578
Cancer 18 | 2,499
lung cancer 18 | 4,740
primitive neuroectodermal tumor 17 | 3,035
malignant mesothelioma 16 | 3,232
pituitary cancer 16 | 1,972
subependymal giant cell astrocytoma 15 | 2,287
Astrocytoma, Pilocytic 13 | 3,081
Schizophrenia 13 | 1,160
adult high grade glioma 13 | 3,801
astrocytic glioma 13 | 2,597
Epilepsy 12 | 792
Intellectual disability 12 | 1,016
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
invasive ductal carcinoma 11 | 2,951
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
Muscle hypotonia 9 | 571
Seizures 9 | 596
diabetes mellitus 9 | 1,728
interstitial cystitis 9 | 2,312
non-small cell lung cancer 9 | 2,890
Alzheimer's disease 8 | 658
Cryptorchidism 8 | 296
Multiple Sclerosis 8 | 540
Small head 8 | 374
lung adenocarcinoma 8 | 2,716
Dull intelligence 7 | 645
Kidney cancer 7 | 2,613
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental deficiency 7 | 645
Poor school performance 7 | 645
astrocytoma 7 | 1,146
colon cancer 7 | 1,478
group 4 medulloblastoma 7 | 1,855
lung carcinoma 7 | 2,843
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Cerebrovascular disease 6 | 238
Lissencephaly 6 | 69
Multiple myeloma 6 | 1,332
Parkinson's disease 6 | 392
Pick disease 6 | 1,894
Rheumatoid arthritis 6 | 1,191
Short stature 6 | 531
breast carcinoma 6 | 1,638
ductal carcinoma in situ 6 | 1,745
pancreatic cancer 6 | 2,398
pediatric high grade glioma 6 | 1,064
tuberculosis 6 | 2,010
Amyotrophic lateral sclerosis 5 | 451
Brain Ischemia 5 | 110
Cerebellar Ataxia 5 | 304
Cockayne syndrome 5 | 60
Down syndrome 5 | 499
Mental Depression 5 | 333
Microcephaly 5 | 166
Nystagmus 5 | 317
Strabismus 5 | 270
acute quadriplegic myopathy 5 | 1,158
juvenile dermatomyositis 5 | 1,187
Atopic dermatitis 4 | 952
Cataract 4 | 297
Cognitive delay 4 | 608
Congenital hypoplasia of penis 4 | 176
Dementia 4 | 175
Depressive disorder 4 | 409
Glaucoma 4 | 239
Global developmental delay 4 | 608
Hypogonadism 4 | 173
Hypoplastic mandible condyle 4 | 275
Lens Opacities 4 | 231
Liver cancer 4 | 604
Major Depressive Disorder 4 | 301
Mandibular hypoplasia 4 | 275
Melanoma 4 | 711
Mental and motor retardation 4 | 608
Micrognathism 4 | 275
Neurodegenerative disease 4 | 414
Stomach Neoplasms 4 | 300
Toxic encephalopathy 4 | 141
Unipolar Depression 4 | 250
adrenocortical carcinoma 4 | 1,428
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
hepatocellular carcinoma 4 | 547
limb girdle muscular dystrophy 2A 4 | 213
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
ulcerative colitis 4 | 1,819

Tissue

Digestive Tract 54 | 17,369
Endocrine System 53 | 18,159
Nervous System 53 | 16,725
Skin and soft tissues 53 | 17,230
Blood and immune system 52 | 16,909
Female tissues 52 | 17,400
Urinary Tract 52 | 16,678
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Respiratory system 50 | 16,393
Cardiovascular System 47 | 15,192

Target Family

Non-IDG 40 | 12,091
Transcription Factor 7 | 1,400
Enzyme 4 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242

Compartment GO Term

Cul4-RING E3 ubiquitin ligase ... 54 | 54
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase DCLK2 DCLK2 Tchem Kinase -0.89222 8.01 148
Zinc finger protein Aiolos IKZF3 Tbio Transcription Factor -1.82293 59.0 314
Protein cereblon CRBN Tclin Non-IDG -2.33306 211.0 82
Denticleless protein homolog DTL Tbio Non-IDG -1.63065 50.0 160
Glial fibrillary acidic protein GFAP Tbio Non-IDG -3.50578 2828.7 1992
DDB1- and CUL4-associated factor 8 DCAF8 Tdark Non-IDG -0.70899 4.90 50
Neuronal migration protein doublecortin DCX Tbio Non-IDG -3.03115 946.3 449
Pleiotropic regulator 1 PLRG1 Tbio Non-IDG -0.95130 8.77 195
Cullin-5 CUL5 Tbio Non-IDG -1.95870 91.8 188
Neural cell adhesion molecule 1 NCAM1 Tbio Non-IDG -3.58910 3930.7 1982