Development Level

Tdark 36 | 6,588
Tbio 30 | 11,445
Tclin 5 | 613
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, incomple... 5 | 499
decreased circulating chloride... 2 | 30
decreased circulating creatini... 2 | 39
decreased grip strength 2 | 116
decreased lean body mass 2 | 135
increased circulating chloride... 2 | 41
increased lean body mass 2 | 172
short tibia 2 | 97
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal heart morphology 1 | 162
abnormal radius morphology 1 | 8
abnormal response to tactile s... 1 | 17
abnormal sleep behavior 1 | 70
abnormal vertebral arch morpho... 1 | 9
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased hemoglobin content 1 | 68
decreased respiratory quotient 1 | 16
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
impaired righting response 1 | 26
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating HDL chol... 1 | 80
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating creatini... 1 | 38
increased circulating glucose ... 1 | 24
increased circulating magnesiu... 1 | 10
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart weight 1 | 62
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small adrenal glands 1 | 16
small thymus 1 | 16

Disease

Carcinoma 52 | 11,493
medulloblastoma, large-cell 35 | 6,241
osteosarcoma 34 | 7,950
ovarian cancer 34 | 8,520
glioblastoma 28 | 5,792
atypical teratoid / rhabdoid tumor 25 | 5,112
psoriasis 20 | 6,694
ependymoma 19 | 4,679
group 4 medulloblastoma 17 | 1,855
oligodendroglioma 17 | 2,850
Astrocytoma, Pilocytic 16 | 3,081
adult high grade glioma 16 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
group 3 medulloblastoma 15 | 4,104
primitive neuroectodermal tumor 14 | 3,035
lung cancer 13 | 4,740
malignant mesothelioma 13 | 3,232
Breast cancer 12 | 3,578
invasive ductal carcinoma 12 | 2,951
tuberculosis 12 | 2,010
subependymal giant cell astrocytoma 11 | 2,287
Kidney cancer 10 | 2,613
astrocytic glioma 10 | 2,597
lung carcinoma 10 | 2,843
interstitial cystitis 9 | 2,312
pancreatic cancer 9 | 2,398
pituitary cancer 9 | 1,972
Cancer 8 | 2,499
ulcerative colitis 8 | 1,819
aldosterone-producing adenoma 7 | 665
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
adrenocortical carcinoma 6 | 1,428
breast carcinoma 6 | 1,638
gastric cancer 6 | 459
gastric carcinoma 6 | 807
non-small cell lung cancer 6 | 2,890
pediatric high grade glioma 6 | 1,064
spina bifida 6 | 1,074
Multiple myeloma 5 | 1,332
diabetes mellitus 5 | 1,728
hepatocellular carcinoma 5 | 547
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
sarcoidosis 5 | 370
sonic hedgehog group medulloblastoma 5 | 467
Acquired metabolic disease 4 | 336
Nemaline myopathy 4 | 17
Pick disease 4 | 1,894
Pseudohypoaldosteronism 4 | 23
acute myeloid leukemia 4 | 783
pancreatic carcinoma 4 | 562
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Autosomal recessive predisposition 3 | 1,442
Congenital myopathy 3 | 16
Malaria 3 | 160
Multiple Sclerosis 3 | 540
Parkinson's disease 3 | 392
Rheumatoid arthritis 3 | 1,191
active Crohn's disease 3 | 922
astrocytoma 3 | 1,146
atypical teratoid/rhabdoid tumor 3 | 357
juvenile dermatomyositis 3 | 1,187
lung adenocarcinoma 3 | 2,716
nasopharyngeal carcinoma 3 | 1,058
posterior fossa group A ependymoma 3 | 468
tuberculosis and treatment for 6 months 3 | 409
Acute Promyelocytic Leukemia 2 | 40
Alzheimer's disease 2 | 658
Anemia 2 | 365
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Cardiovascular system disease 2 | 246
Dystonia 2 | 164
Gaucher disease type 1 2 | 180
Hypersensitivity reaction type II disease 2 | 253
Hypertension 2 | 396
Kidney disease 2 | 430
Leukemia, Myelocytic, Acute 2 | 120
Leukemia, Myeloid, Acute 2 | 105
Lipid metabolism disorder 2 | 114
Liver Cirrhosis, Experimental 2 | 769
Mental Depression 2 | 333
Metabolic acidosis 2 | 90
Orofacial cleft 2 | 54
Precursor Cell Lymphoblastic Leukemia-Lymphoma 2 | 49
Prostatic Neoplasms 2 | 495
Renal Cell Carcinoma 2 | 214
Somatic mutation 2 | 61
Thrombocytopenia 2 | 197
Type 2 diabetes mellitus 2 | 272
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
fibroadenoma 2 | 559
mucosa-associated lymphoid tissue lymphoma 2 | 484
type II diabetes mellitus and post-ischemic heart failure 2 | 88

Tissue

Endocrine System 72 | 18,159
Nervous System 71 | 16,725
Skin and soft tissues 71 | 17,230
Male tissues 70 | 17,142
Digestive Tract 69 | 17,369
Blood and immune system 68 | 16,909
Female tissues 68 | 17,400
Liver and Pancreas 67 | 16,750
Respiratory system 67 | 16,393
Urinary Tract 67 | 16,678
Cardiovascular System 65 | 15,192

Target Family

Non-IDG 66 | 12,091
Kinase 2 | 634
Transcription Factor 2 | 1,400
Enzyme 1 | 4,145
Nuclear Receptor 1 | 48

Compartment GO Term

Cul3-RING ubiquitin ligase com... 72 | 72
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BTB/POZ domain-containing protein KCTD5 KCTD5 Tbio Non-IDG -1.70628 50.2 52
Kelch-like protein 5 KLHL5 Tdark Non-IDG 0.04 0.81 49
PML-RARA-regulated adapter molecule 1 PRAM1 Tbio Non-IDG -2.18597 152.1 104
Kelch-like protein 21 KLHL21 Tbio Non-IDG -0.32074 2.17 65
Kelch repeat and BTB domain-containing protein 6 KBTBD6 Tdark Non-IDG 0.85 0.22 40
Abelson tyrosine-protein kinase 2 ABL2 Tchem Kinase -1.86293 71.2 358
Kelch-like protein 32 KLHL32 Tdark Non-IDG 0.18 0.58 64
Kelch repeat and BTB domain-containing protein 12 KBTBD12 Tdark Non-IDG 1.00 0.08 24
Kelch repeat and BTB domain-containing protein 3 KBTBD3 Tdark Non-IDG 0.00000 57
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184