Development Level

Tbio 22 | 11,445

IMPC Phenotype

abnormal vocalization 1 | 21
improved glucose tolerance 1 | 79
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 20 | 11,493
Kidney cancer 14 | 2,613
Breast cancer 12 | 3,578
glioblastoma 12 | 5,792
lung cancer 12 | 4,740
ovarian cancer 12 | 8,520
psoriasis 12 | 6,694
invasive ductal carcinoma 11 | 2,951
colon cancer 10 | 1,478
ependymoma 10 | 4,679
Liver cancer 9 | 604
atypical teratoid / rhabdoid tumor 9 | 5,112
group 3 medulloblastoma 9 | 4,104
pancreatic cancer 9 | 2,398
Endometrial cancer 8 | 311
Myopathy 8 | 185
ductal carcinoma in situ 8 | 1,745
medulloblastoma, large-cell 8 | 6,241
oligodendroglioma 8 | 2,850
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
lung adenocarcinoma 7 | 2,716
lung carcinoma 7 | 2,843
non-small cell lung cancer 7 | 2,890
primitive neuroectodermal tumor 7 | 3,035
breast carcinoma 6 | 1,638
osteosarcoma 6 | 7,950
Autosomal recessive predisposition 5 | 1,442
Cardiomyopathy 5 | 116
Creatine phosphokinase serum increased 5 | 110
Elevated creatine kinase 5 | 110
Skin cancer 5 | 469
adrenocortical carcinoma 5 | 1,428
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
DOID:2627 4 | 94
Immune system cancer 4 | 140
Melanoma 4 | 711
Muscle biopsy shows dystrophic changes 4 | 39
Muscular dystrophy 4 | 75
Neoplasm Invasiveness 4 | 161
cutaneous lupus erythematosus 4 | 1,057
dermatomyositis 4 | 966
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
limb-girdle muscular dystrophy 4 | 37
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Adult onset 3 | 82
Amyotrophic lateral sclerosis 3 | 451
Atopic dermatitis 3 | 952
Becker muscular dystrophy 3 | 191
COPD 3 | 118
Cardiac Arrhythmia 3 | 103
Cardiomyopathy, Dilated 3 | 83
Decreased tendon reflex 3 | 122
Difficulty walking up stairs 3 | 12
Dilated cardiomyopathy 3 | 56
Duchenne muscular dystrophy 3 | 601
Dull intelligence 3 | 645
Familial isolated dilated cardiomyopathy 3 | 41
Generalized muscle weakness 3 | 57
Gowers sign 3 | 24
Gowers sign present 3 | 24
Infantile onset 3 | 238
Intellectual disability 3 | 1,016
LEFT VENTRICULAR NONCOMPACTION 10 3 | 40
LEFT VENTRICULAR NONCOMPACTION 8 3 | 40
Large intestine cancer 3 | 126
Low intelligence 3 | 645
Lymphoid leukemia 3 | 160
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Motor delay 3 | 147
Muscle Weakness 3 | 170
Muscle hypotonia 3 | 571
No development of motor milestones 3 | 147
Pick disease 3 | 1,894
Poor school performance 3 | 645
Proximal muscle weakness 3 | 47
Proximal neurogenic muscle weakness 3 | 47
Respiratory Failure 3 | 104
Waddling gait 3 | 34
acute myeloid leukemia 3 | 783
acute quadriplegic myopathy 3 | 1,158
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
hereditary spastic paraplegia 3 | 318
pediatric high grade glioma 3 | 1,064
subependymal giant cell astrocytoma 3 | 2,287
Acquired scoliosis 2 | 281
Cancer 2 | 2,499
Curvature of spine 2 | 282
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 19 | 12,091
Enzyme 2 | 4,145
Kinase 1 | 634

Compartment GO Term

Costamere 22 | 22
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Small muscular protein SMPX Tbio Non-IDG -1.24150 17.2 48
Talin-2 TLN2 Tbio Non-IDG -1.36153 20.0 101
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Titin TTN Tbio Kinase -3.24415 1743.0 123
Synemin SYNM Tbio Non-IDG -1.91854 92.6 68
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.65508 52.1 119
Cardiomyopathy-associated protein 5 CMYA5 Tbio Non-IDG -1.08547 15.5 29
Ribonucleoprotein PTB-binding 1 RAVER1 Tbio Non-IDG -0.94201 11.2 91
Dystroglycan DAG1 Tbio Enzyme -2.77503 560.0 254
Keratin, type I cytoskeletal 19 KRT19 Tbio Non-IDG -3.23530 1627.1 1789