Development Level

Tbio 73 | 11,445
Tchem 12 | 1,598
Tclin 5 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 8 | 979
preweaning lethality, incomple... 6 | 499
decreased body weight 5 | 161
abnormal behavior 3 | 298
decreased circulating HDL chol... 3 | 68
decreased circulating LDL chol... 3 | 38
decreased circulating serum al... 3 | 82
enlarged heart 3 | 210
increased circulating chloride... 3 | 41
increased lean body mass 3 | 172
abnormal coat appearance 2 | 31
abnormal cranium morphology 2 | 36
abnormal nail morphology 2 | 8
decreased circulating alanine ... 2 | 47
decreased circulating calcium ... 2 | 36
decreased circulating choleste... 2 | 93
decreased circulating total pr... 2 | 49
decreased grip strength 2 | 116
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged kidney 2 | 14
hypoactivity 2 | 132
increased bone mineral content 2 | 108
increased circulating alkaline... 2 | 122
increased circulating phosphat... 2 | 26
increased circulating sodium l... 2 | 71
prolonged QT interval 2 | 38
prolonged ST segment 2 | 36
short tibia 2 | 97
tremors 2 | 39
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal chorioallantoic fusio... 1 | 8
abnormal digit morphology 1 | 10
abnormal ear morphology 1 | 9
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb position 1 | 3
abnormal locomotor activation 1 | 16
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal sleep behavior 1 | 70
abnormal vertebrae morphology 1 | 18
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased exploration in new e... 1 | 11
decreased glycosylated hemoglo... 1 | 1
decreased heart left ventricle... 1 | 28
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean platelet volume 1 | 25
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased total retina thickne... 1 | 17
enlarged uterus 1 | 11
female infertility 1 | 60
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased prepulse inhibition 1 | 32
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
pallor 1 | 34
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74
thin ventricular wall 1 | 24

Disease

Carcinoma 78 | 11,493
ovarian cancer 55 | 8,520
osteosarcoma 53 | 7,950
glioblastoma 45 | 5,792
psoriasis 44 | 6,694
ependymoma 43 | 4,679
medulloblastoma, large-cell 42 | 6,241
lung cancer 41 | 4,740
Kidney cancer 39 | 2,613
atypical teratoid / rhabdoid tumor 39 | 5,112
Astrocytoma, Pilocytic 34 | 3,081
group 3 medulloblastoma 34 | 4,104
oligodendroglioma 34 | 2,850
primitive neuroectodermal tumor 32 | 3,035
Breast cancer 31 | 3,578
astrocytic glioma 31 | 2,597
pancreatic cancer 31 | 2,398
Cancer 29 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 29 | 3,291
subependymal giant cell astrocytoma 28 | 2,287
adult high grade glioma 27 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
invasive ductal carcinoma 25 | 2,951
lung adenocarcinoma 24 | 2,716
lung carcinoma 22 | 2,843
malignant mesothelioma 22 | 3,232
non-small cell lung cancer 22 | 2,890
ductal carcinoma in situ 21 | 1,745
breast carcinoma 20 | 1,638
diabetes mellitus 18 | 1,728
acute quadriplegic myopathy 17 | 1,158
Pick disease 16 | 1,894
Schizophrenia 16 | 1,160
colon cancer 16 | 1,478
Liver cancer 15 | 604
primary pancreatic ductal adenocarcinoma 15 | 1,109
ulcerative colitis 15 | 1,819
Duchenne muscular dystrophy 14 | 601
interstitial cystitis 14 | 2,312
juvenile dermatomyositis 14 | 1,187
pituitary cancer 14 | 1,972
Melanoma 13 | 711
dermatomyositis 13 | 966
group 4 medulloblastoma 13 | 1,855
Autosomal recessive predisposition 12 | 1,442
Hypertension 12 | 396
adrenocortical carcinoma 12 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Alzheimer's disease 11 | 658
Multiple myeloma 11 | 1,332
Osteoporosis 11 | 363
Skin cancer 11 | 469
tuberculosis 11 | 2,010
Down syndrome 10 | 499
Epilepsy 10 | 792
Heart disease 10 | 306
Liver Cirrhosis, Experimental 10 | 769
Waldenstrons macroglobulinemia 10 | 765
Anemia 9 | 365
Cerebrovascular disease 9 | 238
Endometrial cancer 9 | 311
Hereditary elliptocytosis 9 | 22
Intellectual disability 9 | 1,016
astrocytoma 9 | 1,146
esophageal adenocarcinoma 9 | 737
pancreatic carcinoma 9 | 562
Amyotrophic lateral sclerosis 7 | 451
Anemia, Hemolytic 7 | 55
Becker muscular dystrophy 7 | 191
Breast Neoplasms 7 | 445
Gaucher disease type 1 7 | 180
Kidney disease 7 | 430
Neuropathy 7 | 261
Polycystic ovary syndrome 7 | 360
Rheumatoid arthritis 7 | 1,191
active ulcerative colitis 7 | 764
cutaneous lupus erythematosus 7 | 1,057
gastric carcinoma 7 | 807
non primary Sjogren syndrome sicca 7 | 891
pediatric high grade glioma 7 | 1,064
sarcoidosis 7 | 370
Bipolar Disorder 6 | 666
Cognitive delay 6 | 608
Global developmental delay 6 | 608
Mammary Neoplasms 6 | 425
Mental and motor retardation 6 | 608
Myopathy 6 | 185
Seizures 6 | 596
Short stature 6 | 531
active Crohn's disease 6 | 922
chronic rhinosinusitis 6 | 512
cystic fibrosis 6 | 1,696
fibroadenoma 6 | 559
gastric cancer 6 | 459
mucosa-associated lymphoid tissue lymphoma 6 | 484
nasopharyngeal carcinoma 6 | 1,058
progressive supranuclear palsy 6 | 676
spina bifida 6 | 1,074

Tissue

Endocrine System 91 | 18,159
Skin and soft tissues 91 | 17,230
Female tissues 90 | 17,400
Digestive Tract 89 | 17,369
Liver and Pancreas 89 | 16,750
Blood and immune system 88 | 16,909
Nervous System 87 | 16,725
Respiratory system 87 | 16,393
Urinary Tract 87 | 16,678
Male tissues 85 | 17,142
Cardiovascular System 83 | 15,192

Target Family

Non-IDG 73 | 12,091
Enzyme 11 | 4,145
GPCR 2 | 408
Ion Channel 2 | 344
Kinase 2 | 634
Transporter 2 | 473

Compartment GO Term

Cortical cytoskeleton 92 | 92
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Nuclear mitotic apparatus protein 1 NUMA1 Tbio Non-IDG -2.76544 575.8 235
LIM and SH3 domain protein 1 LASP1 Tbio Non-IDG -1.87137 77.5 299
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Spectrin beta chain, non-erythrocytic 2 SPTBN2 Tbio Non-IDG -1.73436 53.8 237
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.23613 1628.1 165
Pleckstrin homology domain-containing family H member 2 PLEKHH2 Tdark Non-IDG -0.29583 3.51 72
Cysteine--tRNA ligase, cytoplasmic CARS Tbio Enzyme -3.00492 954.7 154