Development Level

Tbio 60 | 11,445
Tchem 8 | 1,598
Tclin 5 | 613
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, complete... 7 | 979
preweaning lethality, incomple... 5 | 499
decreased body weight 3 | 161
abnormal cranium morphology 2 | 36
abnormal nail morphology 2 | 8
decreased circulating serum al... 2 | 82
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
enlarged heart 2 | 210
enlarged kidney 2 | 14
increased circulating alkaline... 2 | 122
short tibia 2 | 97
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal coat appearance 1 | 31
abnormal digit morphology 1 | 10
abnormal ear morphology 1 | 9
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal head morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal kidney morphology 1 | 65
abnormal limb position 1 | 3
abnormal locomotor activation 1 | 16
abnormal pancreas morphology 1 | 13
abnormal retina morphology 1 | 71
abnormal vibrissa morphology 1 | 25
absent startle reflex 1 | 24
cataract 1 | 92
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
decreased circulating total pr... 1 | 49
decreased glycosylated hemoglo... 1 | 1
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
female infertility 1 | 60
hypoactivity 1 | 132
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating phosphat... 1 | 26
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
polycystic kidney 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small superior vagus ganglion 1 | 74
tremors 1 | 39

Disease

Carcinoma 63 | 11,493
osteosarcoma 47 | 7,950
ovarian cancer 44 | 8,520
glioblastoma 38 | 5,792
ependymoma 35 | 4,679
psoriasis 35 | 6,694
Kidney cancer 32 | 2,613
atypical teratoid / rhabdoid tumor 32 | 5,112
lung cancer 32 | 4,740
medulloblastoma, large-cell 32 | 6,241
Astrocytoma, Pilocytic 30 | 3,081
Breast cancer 27 | 3,578
Cancer 27 | 2,499
group 3 medulloblastoma 27 | 4,104
oligodendroglioma 26 | 2,850
pancreatic cancer 26 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
astrocytic glioma 24 | 2,597
invasive ductal carcinoma 24 | 2,951
primitive neuroectodermal tumor 23 | 3,035
adult high grade glioma 22 | 3,801
lung adenocarcinoma 22 | 2,716
ductal carcinoma in situ 21 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
subependymal giant cell astrocytoma 21 | 2,287
intraductal papillary-mucinous adenoma (IPMA) 20 | 2,955
non-small cell lung cancer 20 | 2,890
breast carcinoma 19 | 1,638
malignant mesothelioma 18 | 3,232
diabetes mellitus 17 | 1,728
lung carcinoma 17 | 2,843
Schizophrenia 14 | 1,160
acute quadriplegic myopathy 14 | 1,158
colon cancer 14 | 1,478
Melanoma 13 | 711
primary pancreatic ductal adenocarcinoma 13 | 1,109
Duchenne muscular dystrophy 12 | 601
Pick disease 12 | 1,894
pituitary cancer 12 | 1,972
ulcerative colitis 12 | 1,819
Autosomal recessive predisposition 11 | 1,442
Liver cancer 11 | 604
Skin cancer 11 | 469
adrenocortical carcinoma 11 | 1,428
interstitial cystitis 11 | 2,312
Anemia 10 | 365
Multiple myeloma 10 | 1,332
Osteoporosis 10 | 363
Hereditary elliptocytosis 9 | 22
Hypertension 9 | 396
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
dermatomyositis 9 | 966
juvenile dermatomyositis 9 | 1,187
tuberculosis 9 | 2,010
Alzheimer's disease 8 | 658
Down syndrome 8 | 499
Endometrial cancer 8 | 311
Epilepsy 8 | 792
Heart disease 8 | 306
Intellectual disability 8 | 1,016
Liver Cirrhosis, Experimental 8 | 769
Waldenstrons macroglobulinemia 8 | 765
astrocytoma 8 | 1,146
esophageal adenocarcinoma 8 | 737
group 4 medulloblastoma 8 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Anemia, Hemolytic 7 | 55
Breast Neoplasms 7 | 445
Neuropathy 7 | 261
Rheumatoid arthritis 7 | 1,191
active ulcerative colitis 7 | 764
Amyotrophic lateral sclerosis 6 | 451
Becker muscular dystrophy 6 | 191
Congenital hemolytic anemia 6 | 32
Gaucher disease type 1 6 | 180
Kidney disease 6 | 430
Mammary Neoplasms 6 | 425
Myopathy 6 | 185
Polycystic ovary syndrome 6 | 360
active Crohn's disease 6 | 922
chronic rhinosinusitis 6 | 512
cutaneous lupus erythematosus 6 | 1,057
cystic fibrosis 6 | 1,696
fibroadenoma 6 | 559
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
progressive supranuclear palsy 6 | 676
sarcoidosis 6 | 370
Cognitive delay 5 | 608
Dull intelligence 5 | 645
Global developmental delay 5 | 608
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental and motor retardation 5 | 608
Mental deficiency 5 | 645
Poor school performance 5 | 645
Short stature 5 | 531
gastric carcinoma 5 | 807
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074

Tissue

Endocrine System 74 | 18,159
Skin and soft tissues 74 | 17,230
Female tissues 73 | 17,400
Liver and Pancreas 72 | 16,750
Blood and immune system 71 | 16,909
Digestive Tract 71 | 17,369
Nervous System 69 | 16,725
Respiratory system 69 | 16,393
Urinary Tract 69 | 16,678
Male tissues 68 | 17,142
Cardiovascular System 65 | 15,192

Target Family

Non-IDG 57 | 12,091
Enzyme 12 | 4,145
GPCR 2 | 408
Kinase 2 | 634
Ion Channel 1 | 344
Transporter 1 | 473

Compartment GO Term

Cortical actin cytoskeleton 75 | 75
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,237 | 12,237
Intracellular organelle 12,023 | 12,023
membrane-bounded organelle 11,130 | 11,130
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,340 | 10,340
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,561 | 7,561
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,972 | 3,972
non-membrane-bounded organelle 3,972 | 3,972
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,955 | 1,955
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,547 | 1,547
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,123 | 1,123
Nuclear outer membrane-endopla... 1,121 | 1,121
Nucleoplasm part 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,040 | 1,040
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 949 | 949
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 848 | 848
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Glycophorin-C GYPC Tbio Non-IDG -2.88194 722.9 302
LIM and SH3 domain protein 1 LASP1 Tbio Non-IDG -1.87137 77.5 299
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Myocardial zonula adherens protein POLR2M Tbio Non-IDG -1.87592 70.6 20
Ankyrin-2 ANK2 Tbio Non-IDG -2.08421 120.5 236
Spectrin alpha chain, non-erythrocytic 1 SPTAN1 Tbio Non-IDG -2.42514 269.0 268
Transient receptor potential cation channel subfamily V member 4 TRPV4 Tchem Ion Channel -2.86016 747.3 258
Radixin RDX Tbio Non-IDG -2.47844 221.4 333
Spectrin beta chain, erythrocytic SPTB Tbio Non-IDG -2.45982 275.1 59