Development Level

Tbio 139 | 10,625
Tchem 22 | 1,890
Tclin 16 | 602
Tdark 14 | 7,003

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

preweaning lethality, complete... 13 | 633
decreased bone mineral content 7 | 157
abnormal behavior 5 | 226
abnormal embryo size 4 | 112
decreased bone mineral density 4 | 126
decreased circulating choleste... 4 | 85
decreased lean body mass 4 | 195
hyperactivity 4 | 108
abnormal behavioral response t... 3 | 52
abnormal bone structure 3 | 131
decreased circulating HDL chol... 3 | 77
decreased startle reflex 3 | 48
increased bone mineral density 3 | 52
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
abnormal sleep behavior 2 | 63
abnormal vocalization 2 | 21
decreased body weight 2 | 174
decreased circulating LDL chol... 2 | 37
decreased circulating glucose ... 2 | 121
decreased circulating total pr... 2 | 41
decreased grip strength 2 | 123
decreased vertical activity 2 | 22
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased body weight 2 | 42
increased heart weight 2 | 37
increased or absent threshold ... 2 | 128
increased vertical activity 2 | 18
preweaning lethality, incomple... 2 | 260
abnormal digit morphology 1 | 13
abnormal epididymis morphology 1 | 31
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal limb position 1 | 3
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal spinal cord morpholog... 1 | 8
abnormal thoracic vertebrae mo... 1 | 16
abnormal urinary bladder morph... 1 | 2
absent heartbeat 1 | 6
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
convulsive seizures 1 | 11
cyanosis 1 | 6
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
decreased mature B cell number 1 | 25
decreased threshold for audito... 1 | 32
edema 1 | 11
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
prenatal lethality 1 | 16
prolonged PR interval 1 | 4
respiratory system phenotype 1 | 2
short tibia 1 | 82
shortened PQ interval 1 | 6
shortened PR interval 1 | 5
shortened ST segment 1 | 9

Disease

psoriasis 92 | 6,685
ovarian cancer 81 | 8,484
glioblastoma 78 | 5,572
medulloblastoma, large-cell 72 | 6,234
lung cancer 67 | 4,466
osteosarcoma 66 | 7,933
atypical teratoid / rhabdoid tumor 59 | 4,369
Carcinoma 56 | 2,147
lung adenocarcinoma 53 | 2,713
invasive ductal carcinoma 50 | 2,950
acute quadriplegic myopathy 48 | 1,157
primitive neuroectodermal tumor 48 | 3,031
malignant mesothelioma 46 | 3,162
Breast cancer 45 | 3,094
colon cancer 45 | 1,475
lung carcinoma 44 | 2,844
non-small cell lung cancer 44 | 2,798
pancreatic cancer 44 | 2,300
intraductal papillary-mucinous carcinoma (IPMC) 43 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,956
pilocytic astrocytoma 42 | 3,086
pediatric high grade glioma 41 | 2,712
oligodendroglioma 37 | 2,849
Cancer 36 | 2,346
Myopathy 36 | 128
Heart disease 35 | 279
diabetes mellitus 34 | 1,663
ependymoma 32 | 2,514
subependymal giant cell astrocytoma 32 | 2,287
Cardiomyopathy 31 | 110
breast carcinoma 30 | 1,614
cystic fibrosis 29 | 1,665
adult high grade glioma 28 | 2,148
astrocytic glioma 28 | 2,241
ductal carcinoma in situ 28 | 1,745
ulcerative colitis 28 | 2,087
primary pancreatic ductal adenocarcinoma 27 | 1,271
pituitary cancer 25 | 1,972
Dilated cardiomyopathy 24 | 50
group 4 medulloblastoma 24 | 1,875
Duchenne muscular dystrophy 23 | 602
Hypertrophic Cardiomyopathy 23 | 56
astrocytoma 23 | 1,493
medulloblastoma 23 | 1,524
Coronary artery disease 22 | 240
Pick disease 22 | 1,893
tuberculosis 22 | 1,557
Cerebrovascular disease 21 | 231
posterior fossa group A ependymoma 21 | 1,511
Cardiomyopathies 20 | 90
adrenocortical carcinoma 20 | 1,427
dermatomyositis 20 | 933
Amyotrophic Lateral Sclerosis 18 | 431
Rheumatoid Arthritis 18 | 1,160
group 3 medulloblastoma 18 | 2,254
sonic hedgehog group medulloblastoma 18 | 1,482
Hypertension 17 | 287
juvenile dermatomyositis 17 | 1,189
nasopharyngeal carcinoma 17 | 1,056
Kidney disease 16 | 396
Myocardial Infarction 16 | 126
spina bifida 16 | 1,064
Atrial Fibrillation 15 | 110
Cardiomyopathy, Dilated 15 | 47
Alzheimer's disease 14 | 644
Cardiomyopathy, Hypertrophic, Familial 14 | 21
Distal arthrogryposis 14 | 45
Nemaline myopathy 14 | 17
Obesity 14 | 616
atypical teratoid/rhabdoid tumor 14 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 14 | 499
interstitial cystitis 14 | 2,299
Atopic dermatitis 13 | 944
Epilepsy 13 | 346
pancreatic carcinoma 13 | 567
posterior fossa group B ependymoma 13 | 1,530
Anemia 12 | 252
Asthma 12 | 349
Kidney cancer 12 | 118
Primary cutaneous amyloidosis 12 | 26
cutaneous lupus erythematosus 12 | 1,056
gastric carcinoma 12 | 832
Amyloidosis 11 | 68
Atherosclerosis 11 | 275
Becker muscular dystrophy 11 | 187
Malignant hyperthermia 11 | 25
Multiple myeloma 11 | 1,327
active ulcerative colitis 11 | 477
gastric cancer 11 | 430
interstitial lung disease 11 | 291
Acute coronary syndrome 10 | 37
Down syndrome 10 | 548
Myocardial Ischemia 10 | 169
Neuropathy 10 | 210
Schizophrenia 10 | 501
Waldenstrons macroglobulinemia 10 | 765
active Crohn's disease 10 | 918
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
esophageal adenocarcinoma 9 | 737

Tissue

Cardiovascular System 191 | 17,958
Digestive Tract 191 | 18,473
Endocrine System 191 | 18,512
Female tissues 191 | 18,647
Liver and Pancreas 191 | 18,136
Male tissues 191 | 17,969
Nervous System 191 | 18,561
Skin and soft tissues 191 | 18,115
Urinary Tract 191 | 18,444
Blood and immune system 190 | 17,995
Respiratory system 190 | 17,484

Target Family

Non-IDG 138 | 11,971
Enzyme 22 | 4,146
Ion Channel 12 | 341
Kinase 7 | 634
Transcription Factor 7 | 1,400
Transporter 4 | 473
Epigenetic 1 | 242

Compartment GO Term

Contractile fiber part 191 | 191
cellular_component 18,238 | 18,238
Cell 15,807 | 15,807
Cell part 15,807 | 15,807
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,649 | 12,649
membrane-bounded organelle 11,794 | 11,794
Intracellular organelle 11,618 | 11,618
Intracellular membrane-bounded... 10,619 | 10,619
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,170 | 8,170
Intracellular organelle part 8,012 | 8,012
Cytoplasmic part 7,830 | 7,830
Nucleus 6,897 | 6,897
Membrane part 6,469 | 6,469
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,172 | 5,172
Cell periphery 5,145 | 5,145
Plasma membrane 5,059 | 5,059
Extracellular region 4,606 | 4,606
Protein complex 4,438 | 4,438
Intracellular organelle lumen 4,331 | 4,331
Organelle lumen 4,331 | 4,331
membrane-enclosed lumen 4,331 | 4,331
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,840 | 3,840
non-membrane-bounded organelle 3,839 | 3,839
Nuclear part 3,808 | 3,808
Endomembrane system 3,720 | 3,720
Vesicle 3,667 | 3,667
membrane-bounded vesicle 3,495 | 3,495
Nuclear lumen 3,465 | 3,465
Cytosol 3,352 | 3,352
Nucleoplasm 2,938 | 2,938
Extracellular organelle 2,850 | 2,850
Extracellular vesicle 2,849 | 2,849
Extracellular exosome 2,829 | 2,829
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,563 | 2,563
Cytoskeleton 2,045 | 2,045
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Endoplasmic reticulum 1,663 | 1,663
Cytoskeletal part 1,567 | 1,567
Mitochondrion 1,530 | 1,530
Cell projection 1,426 | 1,426
Golgi apparatus 1,402 | 1,402
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,304 | 1,304
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,233 | 1,233
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Chromosome 999 | 999
Mitochondrial part 989 | 989
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 794 | 794
Intracellular ribonucleoprotei... 790 | 790
Nucleoplasm part 780 | 780
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 738 | 738
Plasma membrane protein comple... 720 | 720
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Microtubule organizing center 617 | 617
Synapse 594 | 594
Lysosome 571 | 571
Lytic vacuole 571 | 571
Vesicle membrane 559 | 559
cell-cell junction 557 | 557
Cytoplasmic vesicle membrane 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Myosin light chain 6B MYL6B Tdark Non-IDG -0.43175 2.57 113
Neuroblast differentiation-associated protein AHNAK AHNAK Tbio Non-IDG -1.61845 51.3 82
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -1.95188 93.8 215
Synemin SYNM Tbio Non-IDG -1.91137 94.9 56
Band 3 anion transport protein SLC4A1 Tbio Transporter -3.02453 1271.7 133
Protein unc-45 homolog B UNC45B Tbio Non-IDG -1.52907 38.8 99
DnaJ homolog subfamily B member 6 DNAJB6 Tbio Non-IDG -1.88632 95.9 167
Peptidyl-prolyl cis-trans isomerase FKBP1A FKBP1A Tclin Enzyme -2.75744 370.6 255
Sarcoplasmic reticulum histidine-rich calcium-binding protein HRC Tbio Non-IDG -2.29405 210.5 51