Development Level

Tbio 147 | 11,178
Tchem 25 | 1,885
Tclin 16 | 612
Tdark 14 | 6,569

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 20 | 979
abnormal embryo size 6 | 220
embryonic lethality prior to t... 5 | 278
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
abnormal bone structure 4 | 187
decreased circulating glucose ... 4 | 126
hyperactivity 4 | 148
abnormal behavioral response t... 3 | 66
decreased blood urea nitrogen ... 3 | 51
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased circulating choleste... 3 | 93
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
decreased startle reflex 3 | 75
decreased vertical activity 3 | 208
edema 3 | 59
embryonic lethality prior to o... 3 | 239
hemorrhage 3 | 23
increased heart weight 3 | 62
increased startle reflex 3 | 112
abnormal sleep behavior 2 | 70
abnormal tail morphology 2 | 25
abnormal vocalization 2 | 21
cyanosis 2 | 7
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating total pr... 2 | 49
decreased leukocyte cell numbe... 2 | 73
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body length 2 | 32
increased body weight 2 | 25
increased circulating triglyce... 2 | 42
respiratory system phenotype 2 | 2
tremors 2 | 39
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal urinary bladder morph... 1 | 11
absent startle reflex 1 | 24
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
embryonic growth retardation 1 | 106
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
long tibia 1 | 25
prenatal lethality 1 | 28
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 139 | 11,192
psoriasis 97 | 6,514
ovarian cancer 86 | 8,297
glioblastoma 79 | 5,635
medulloblastoma, large-cell 76 | 6,086
atypical teratoid / rhabdoid tumor 71 | 4,971
lung cancer 70 | 4,607
osteosarcoma 68 | 7,766
Breast cancer 63 | 3,469
Kidney cancer 56 | 2,548
lung adenocarcinoma 56 | 2,627
adult high grade glioma 54 | 3,701
ependymoma 54 | 4,559
pancreatic cancer 51 | 2,322
malignant mesothelioma 50 | 3,135
invasive ductal carcinoma 49 | 2,867
acute quadriplegic myopathy 48 | 1,133
primitive neuroectodermal tumor 48 | 2,957
group 3 medulloblastoma 47 | 4,002
lung carcinoma 47 | 2,755
Myopathy 45 | 185
colon cancer 44 | 1,428
non-small cell lung cancer 44 | 2,799
Cancer 42 | 2,388
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,872
intraductal papillary-mucinous neoplasm (IPMN) 42 | 3,204
Astrocytoma, Pilocytic 41 | 3,006
intraductal papillary-mucinous carcinoma (IPMC) 41 | 2,902
Autosomal recessive predisposition 40 | 1,407
diabetes mellitus 40 | 1,683
Heart disease 38 | 288
Cardiomyopathy 34 | 116
oligodendroglioma 34 | 2,768
subependymal giant cell astrocytoma 34 | 2,230
astrocytic glioma 33 | 2,530
Liver cancer 31 | 589
breast carcinoma 31 | 1,589
cystic fibrosis 30 | 1,629
ductal carcinoma in situ 29 | 1,686
Cardiomyopathy, Dilated 28 | 83
Dilated cardiomyopathy 28 | 56
group 4 medulloblastoma 27 | 1,806
pituitary cancer 27 | 1,915
Hypertrophic Cardiomyopathy 26 | 115
Melanoma 26 | 689
tuberculosis 26 | 1,963
Skin cancer 25 | 451
ulcerative colitis 25 | 1,765
Coronary artery disease 24 | 253
Duchenne muscular dystrophy 24 | 587
Pick disease 24 | 1,856
Cerebrovascular disease 23 | 223
Familial isolated dilated cardiomyopathy 23 | 41
LEFT VENTRICULAR NONCOMPACTION 10 23 | 40
LEFT VENTRICULAR NONCOMPACTION 8 23 | 40
Hypertension 21 | 372
Schizophrenia 21 | 1,136
adrenocortical carcinoma 20 | 1,385
Endometrial cancer 19 | 301
Epilepsy 19 | 775
Heart failure 19 | 157
dermatomyositis 19 | 941
juvenile dermatomyositis 19 | 1,147
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,911
primary pancreatic ductal adenocarcinoma 19 | 1,071
spina bifida 18 | 1,053
Amyotrophic lateral sclerosis 17 | 437
Atrial Fibrillation 17 | 120
Liver Cirrhosis, Experimental 17 | 733
Rheumatoid arthritis 17 | 1,156
astrocytoma 17 | 1,113
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 492
Acquired scoliosis 16 | 274
Alzheimer's disease 16 | 640
Creatine phosphokinase serum increased 16 | 110
Curvature of spine 16 | 275
Elevated creatine kinase 16 | 110
Kidney disease 16 | 411
nasopharyngeal carcinoma 16 | 1,024
Congestive heart failure 15 | 109
Distal arthrogryposis 15 | 41
Myocardial Infarction 15 | 142
Short stature 15 | 514
Amyloidosis 14 | 64
Byzanthine arch palate 14 | 194
Cardiac Arrhythmia 14 | 101
Nemaline myopathy 14 | 17
active ulcerative colitis 14 | 736
interstitial cystitis 14 | 2,237
Asthma 13 | 370
Atopic dermatitis 13 | 915
Bipolar Disorder 13 | 646
Cardiomyopathies 13 | 109
Deglutition Disorders 13 | 128
Muscular dystrophy 13 | 75
Proximal muscle weakness 13 | 47
Proximal neurogenic muscle weakness 13 | 47
Seizures 13 | 584
cutaneous lupus erythematosus 13 | 1,016
pediatric high grade glioma 13 | 1,035

Tissue

Endocrine System 201 | 18,159
Digestive Tract 199 | 17,369
Skin and soft tissues 196 | 17,230
Female tissues 195 | 17,400
Male tissues 195 | 17,142
Blood and immune system 193 | 16,909
Urinary Tract 190 | 16,678
Liver and Pancreas 189 | 16,750
Cardiovascular System 185 | 15,192
Nervous System 183 | 16,725
Respiratory system 177 | 16,393

Target Family

Non-IDG 149 | 12,091
Enzyme 24 | 4,145
Ion Channel 11 | 344
Kinase 8 | 634
Transcription Factor 5 | 1,400
Transporter 4 | 473
Epigenetic 1 | 242

Compartment GO Term

Contractile fiber part 202 | 202
cellular_component 17,863 | 17,863
Cell 15,779 | 15,779
Cell part 15,778 | 15,778
Intracellular 13,764 | 13,764
Intracellular part 13,630 | 13,630
Organelle 11,921 | 11,921
Intracellular organelle 11,712 | 11,712
membrane-bounded organelle 10,823 | 10,823
Cytoplasm 10,720 | 10,720
Intracellular membrane-bounded... 10,057 | 10,057
Cytoplasmic part 9,029 | 9,029
Organelle part 8,755 | 8,755
Intracellular organelle part 8,566 | 8,566
Membrane 8,335 | 8,335
Nucleus 7,336 | 7,336
Cytosol 6,551 | 6,551
Membrane part 6,403 | 6,403
Plasma membrane 5,682 | 5,682
Macromolecular complex 5,345 | 5,345
Intrinsic component of membran... 5,320 | 5,320
Cell periphery 5,248 | 5,248
Integral component of membrane 5,197 | 5,197
Nucleoplasm 4,931 | 4,931
Intracellular organelle lumen 4,923 | 4,923
Organelle lumen 4,923 | 4,923
membrane-enclosed lumen 4,923 | 4,923
Nuclear part 4,169 | 4,169
Endomembrane system 4,108 | 4,108
Intracellular non-membrane-bou... 3,917 | 3,917
non-membrane-bounded organelle 3,917 | 3,917
Nuclear lumen 3,851 | 3,851
Protein complex 3,565 | 3,565
Organelle membrane 2,798 | 2,798
Extracellular region 2,600 | 2,600
Plasma membrane part 2,531 | 2,531
Vesicle 2,280 | 2,280
Cytoplasmic vesicle 2,158 | 2,158
Intracellular vesicle 2,157 | 2,157
Cytoskeleton 2,084 | 2,084
Bounding membrane of organelle 1,924 | 1,924
Endoplasmic reticulum 1,922 | 1,922
Golgi apparatus 1,884 | 1,884
Intrinsic component of plasma ... 1,701 | 1,701
Integral component of plasma m... 1,647 | 1,647
Cytoskeletal part 1,613 | 1,613
Catalytic complex 1,592 | 1,592
Vesicles 1,566 | 1,566
Mitochondrion 1,557 | 1,557
Extracellular region part 1,533 | 1,533
Cell projection 1,524 | 1,524
Whole membrane 1,521 | 1,521
Cytoplasmic vesicle part 1,468 | 1,468
Endoplasmic reticulum part 1,315 | 1,315
GO:0031975 1,139 | 1,139
Organelle envelope 1,131 | 1,131
Microtubule cytoskeleton 1,127 | 1,127
Nucleoplasm part 1,100 | 1,100
Nuclear outer membrane-endopla... 1,094 | 1,094
Endoplasmic reticulum membrane 1,076 | 1,076
Extracellular space 1,059 | 1,059
Mitochondrial part 1,027 | 1,027
Chromosome 1,020 | 1,020
Mitochondria 985 | 985
Neuron part 958 | 958
Supramolecular polymer 950 | 950
Cell junction 949 | 949
Supramolecular complex 949 | 949
Supramolecular fiber 942 | 942
Secretory vesicle 930 | 930
Golgi apparatus part 923 | 923
Nucleoli 923 | 923
Nucleolus 916 | 916
Endosome 915 | 915
Chromosomal part 872 | 872
GO:0098796 868 | 868
Ribonucleoprotein complex 845 | 845
Cell projection part 838 | 838
Transferase complex 837 | 837
Intracellular ribonucleoprotei... 830 | 830
Plasma membrane region 826 | 826
Secretory granule 810 | 810
Cell surface 805 | 805
Vesicle membrane 786 | 786
Cytoplasmic vesicle membrane 780 | 780
Polymeric cytoskeletal fiber 753 | 753
Mitochondrial envelope 739 | 739
Golgi membrane 715 | 715
Microtubule organizing center 712 | 712
Nuclear body 708 | 708
Vacuole 708 | 708
Neuron projection 701 | 701
Mitochondrial membrane 689 | 689
Centrosome 685 | 685
Extracellular matrix 670 | 670
Receptor complex 670 | 670
Synapse 656 | 656
Lysosome 600 | 600
Lytic vacuole 600 | 600
Endosomal part 554 | 554
Chromatin 552 | 552

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ryanodine receptor 1 RYR1 Tclin Ion Channel -3.00978 1018.9 103
Neutrophil gelatinase-associated lipocalin LCN2 Tbio Enzyme -3.35178 2368.1 847
Vinculin VCL Tbio Non-IDG -3.34872 2107.1 637
Myosin light chain 5 MYL5 Tdark Non-IDG -0.64304 3.42 58
Plectin PLEC Tbio Non-IDG -2.50749 337.2 130
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform PPP2R5A Tchem Enzyme -0.54568 3.09 202
Survival motor neuron protein SMN2 Tchem Epigenetic -3.01035 496.0 175
Myozenin-3 MYOZ3 Tdark Non-IDG -0.39925 2.96 19
Keratin, type I cytoskeletal 19 KRT19 Tbio Non-IDG -3.23530 1627.1 1789
Ankyrin repeat domain-containing protein 1 ANKRD1 Tbio Non-IDG -1.79794 62.3 159