Development Level

Tbio 164 | 11,651
Tchem 18 | 1,388
Tclin 18 | 612
Tdark 14 | 6,593

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Comple... 1 | 37
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 22 | 979
abnormal embryo size 7 | 220
embryonic lethality prior to t... 6 | 278
preweaning lethality, incomple... 5 | 499
abnormal behavior 4 | 298
abnormal bone structure 4 | 187
decreased circulating glucose ... 4 | 126
decreased vertical activity 4 | 208
hyperactivity 4 | 148
abnormal behavioral response t... 3 | 66
decreased blood urea nitrogen ... 3 | 51
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased circulating choleste... 3 | 93
decreased grip strength 3 | 116
decreased lean body mass 3 | 135
decreased startle reflex 3 | 75
edema 3 | 59
embryonic lethality prior to o... 3 | 239
hemorrhage 3 | 23
increased heart weight 3 | 62
increased startle reflex 3 | 112
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
abnormal tail morphology 2 | 25
abnormal vocalization 2 | 21
cyanosis 2 | 7
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased circulating HDL chol... 2 | 68
decreased circulating LDL chol... 2 | 38
decreased circulating total pr... 2 | 49
decreased leukocyte cell numbe... 2 | 73
decreased neutrophil cell numb... 2 | 42
decreased total body fat amoun... 2 | 207
embryonic growth retardation 2 | 106
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased body length 2 | 32
increased body weight 2 | 25
increased circulating triglyce... 2 | 42
respiratory system phenotype 2 | 2
tremors 2 | 39
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal response to new envir... 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin condition 1 | 6
abnormal urinary bladder morph... 1 | 11
absent startle reflex 1 | 24
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased anxiety-related resp... 1 | 12
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating creatini... 1 | 39
decreased circulating iron lev... 1 | 32
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased exploration in new e... 1 | 11
decreased heart left ventricle... 1 | 28
decreased heart rate variabili... 1 | 13
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
female infertility 1 | 60
increased blood urea nitrogen ... 1 | 48
increased body temperature 1 | 9
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating chloride... 1 | 41
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
long tibia 1 | 25
prenatal lethality 1 | 28
short tibia 1 | 97
shortened PQ interval 1 | 7
shortened PR interval 1 | 6
small superior vagus ganglion 1 | 74
syndactyly 1 | 23
thin ventricular wall 1 | 24
thrombocytosis 1 | 27

Disease

Carcinoma 150 | 11,493
psoriasis 105 | 6,694
ovarian cancer 92 | 8,520
glioblastoma 84 | 5,792
medulloblastoma, large-cell 79 | 6,241
lung cancer 77 | 4,740
atypical teratoid / rhabdoid tumor 74 | 5,112
osteosarcoma 73 | 7,950
Breast cancer 65 | 3,578
ependymoma 60 | 4,679
Kidney cancer 59 | 2,613
adult high grade glioma 58 | 3,801
lung adenocarcinoma 58 | 2,716
malignant mesothelioma 54 | 3,232
pancreatic cancer 53 | 2,398
acute quadriplegic myopathy 51 | 1,158
invasive ductal carcinoma 51 | 2,951
primitive neuroectodermal tumor 51 | 3,035
group 3 medulloblastoma 49 | 4,104
non-small cell lung cancer 49 | 2,890
colon cancer 47 | 1,478
lung carcinoma 47 | 2,843
Cancer 46 | 2,499
Astrocytoma, Pilocytic 45 | 3,081
Myopathy 45 | 185
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 45 | 3,291
Autosomal recessive predisposition 44 | 1,442
intraductal papillary-mucinous adenoma (IPMA) 44 | 2,955
Heart disease 42 | 306
diabetes mellitus 42 | 1,728
oligodendroglioma 38 | 2,850
astrocytic glioma 37 | 2,597
subependymal giant cell astrocytoma 36 | 2,287
Cardiomyopathy 35 | 116
Liver cancer 33 | 604
breast carcinoma 31 | 1,638
tuberculosis 31 | 2,010
cystic fibrosis 30 | 1,696
group 4 medulloblastoma 30 | 1,855
ductal carcinoma in situ 29 | 1,745
Cardiomyopathy, Dilated 28 | 83
Dilated cardiomyopathy 28 | 56
Hypertrophic Cardiomyopathy 28 | 117
pituitary cancer 28 | 1,972
Coronary artery disease 27 | 268
Duchenne muscular dystrophy 25 | 601
Melanoma 25 | 711
Pick disease 25 | 1,894
Skin cancer 25 | 469
ulcerative colitis 25 | 1,819
Cerebrovascular disease 24 | 238
Familial isolated dilated cardiomyopathy 23 | 41
Hypertension 23 | 396
LEFT VENTRICULAR NONCOMPACTION 10 23 | 40
LEFT VENTRICULAR NONCOMPACTION 8 23 | 40
Schizophrenia 23 | 1,160
Endometrial cancer 21 | 311
Epilepsy 21 | 792
Heart failure 21 | 162
dermatomyositis 21 | 966
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
adrenocortical carcinoma 20 | 1,428
juvenile dermatomyositis 20 | 1,187
primary pancreatic ductal adenocarcinoma 20 | 1,109
Rheumatoid arthritis 19 | 1,191
Amyotrophic lateral sclerosis 18 | 451
Atrial Fibrillation 18 | 124
Kidney disease 18 | 430
Liver Cirrhosis, Experimental 18 | 769
Myocardial Infarction 18 | 151
astrocytoma 18 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 18 | 510
spina bifida 18 | 1,074
Alzheimer's disease 17 | 658
nasopharyngeal carcinoma 17 | 1,058
Acquired scoliosis 16 | 281
Congestive heart failure 16 | 113
Creatine phosphokinase serum increased 16 | 110
Curvature of spine 16 | 282
Elevated creatine kinase 16 | 110
active ulcerative colitis 16 | 764
cutaneous lupus erythematosus 16 | 1,057
interstitial cystitis 16 | 2,312
Amyloidosis 15 | 67
Atopic dermatitis 15 | 952
Cardiac Arrhythmia 15 | 103
Cardiomyopathies 15 | 110
Distal arthrogryposis 15 | 42
Muscle hypotonia 15 | 571
Seizures 15 | 596
Short stature 15 | 531
Anemia 14 | 365
Bipolar Disorder 14 | 666
Byzanthine arch palate 14 | 194
Hypertensive disease 14 | 292
Nemaline myopathy 14 | 17
Respiratory Insufficiency 14 | 132
pediatric high grade glioma 14 | 1,064
Asthma 13 | 385

Tissue

Endocrine System 213 | 18,159
Digestive Tract 211 | 17,369
Skin and soft tissues 208 | 17,230
Female tissues 207 | 17,400
Male tissues 207 | 17,142
Blood and immune system 205 | 16,909
Liver and Pancreas 201 | 16,750
Urinary Tract 201 | 16,678
Cardiovascular System 197 | 15,192
Nervous System 195 | 16,725
Respiratory system 189 | 16,393

Target Family

Non-IDG 155 | 12,091
Enzyme 28 | 4,145
Ion Channel 11 | 344
Kinase 8 | 634
Transcription Factor 7 | 1,400
Transporter 4 | 473
Epigenetic 1 | 242

Compartment GO Term

Contractile fiber 214 | 214
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,783 | 8,783
Membrane 8,530 | 8,530
Nucleus 7,563 | 7,563
Cytosol 6,686 | 6,686
Membrane part 6,553 | 6,553
Plasma membrane 5,829 | 5,829
Macromolecular complex 5,476 | 5,476
Intrinsic component of membran... 5,457 | 5,457
Cell periphery 5,381 | 5,381
Integral component of membrane 5,330 | 5,330
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,974 | 3,974
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,673 | 3,673
Organelle membrane 2,846 | 2,846
Extracellular region 2,731 | 2,731
Plasma membrane part 2,593 | 2,593
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,216 | 2,216
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,638 | 1,638
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 968 | 968
Supramolecular complex 967 | 967
Cell junction 960 | 960
Supramolecular fiber 960 | 960
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 931 | 931
Nucleolus 927 | 927
Chromosomal part 889 | 889
GO:0098796 883 | 883
Ribonucleoprotein complex 864 | 864
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 849 | 849
Transferase complex 849 | 849
Cell surface 841 | 841
Plasma membrane region 841 | 841
Vesicle membrane 800 | 800
Cytoplasmic vesicle membrane 794 | 794
Polymeric cytoskeletal fiber 765 | 765
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 713 | 713
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myosin-13 MYH13 Tbio Non-IDG -1.26079 16.6 12
Myosin-2 MYH2 Tbio Non-IDG -2.14128 114.9 63
Myeloperoxidase MPO Tchem Enzyme -3.51470 3209.3 1255
Endothelin-1 EDN1 Tbio Non-IDG -4.07520 12851.9 607
Serine/threonine-protein kinase PAK 1 PAK1 Tchem Kinase -2.29299 237.8 1060
Myosin light chain kinase, smooth muscle MYLK Tchem Kinase -2.81312 694.0 219
Interleukin-6 IL6 Tclin Non-IDG -4.50976 30968.8 2075
Potassium voltage-gated channel subfamily E member 1 KCNE1 Tbio Ion Channel -2.67495 441.7 193
Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D Tclin Ion Channel -2.43448 273.2 215
N-acetyltransferase 9 NAT9 Tdark Enzyme -3.02820 1070.9 44