Development Level

Tbio 149 | 10,625
Tchem 23 | 1,890
Tclin 16 | 602
Tdark 14 | 7,003

Collection

Ion Channel: IDG Consortium (Targets) 1 | 102
Kinase: IDG Consortium (Complete/Control) 1 | 37

IMPC Phenotype

preweaning lethality, complete... 14 | 633
decreased bone mineral content 7 | 157
abnormal behavior 5 | 226
decreased lean body mass 5 | 195
abnormal embryo size 4 | 112
decreased bone mineral density 4 | 126
decreased circulating choleste... 4 | 85
hyperactivity 4 | 108
abnormal behavioral response t... 3 | 52
abnormal bone structure 3 | 131
decreased body weight 3 | 174
decreased circulating HDL chol... 3 | 77
decreased startle reflex 3 | 48
increased body weight 3 | 42
increased bone mineral density 3 | 52
abnormal lens morphology 2 | 73
abnormal retina morphology 2 | 100
abnormal sleep behavior 2 | 63
abnormal vocalization 2 | 21
decreased circulating LDL chol... 2 | 37
decreased circulating glucose ... 2 | 121
decreased circulating total pr... 2 | 41
decreased grip strength 2 | 123
decreased vertical activity 2 | 22
embryonic lethality prior to o... 2 | 148
embryonic lethality prior to t... 2 | 187
impaired glucose tolerance 2 | 52
improved glucose tolerance 2 | 56
increased heart weight 2 | 37
increased or absent threshold ... 2 | 128
increased vertical activity 2 | 18
preweaning lethality, incomple... 2 | 260
abnormal digit morphology 1 | 13
abnormal epididymis morphology 1 | 31
abnormal facial morphology 1 | 9
abnormal forebrain development 1 | 18
abnormal gait 1 | 51
abnormal hindbrain development 1 | 24
abnormal midbrain development 1 | 22
abnormal neural tube closure 1 | 37
abnormal placenta vasculature 1 | 2
abnormal response to new envir... 1 | 8
abnormal retinal blood vessel ... 1 | 18
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal skin morphology 1 | 23
abnormal spinal cord morpholog... 1 | 8
abnormal thoracic vertebrae mo... 1 | 16
abnormal urinary bladder morph... 1 | 2
absent heartbeat 1 | 6
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
cataract 1 | 26
convulsive seizures 1 | 11
cyanosis 1 | 6
decreased NK cell number 1 | 16
decreased T cell number 1 | 31
decreased anxiety-related resp... 1 | 12
decreased blood urea nitrogen ... 1 | 31
decreased body length 1 | 108
decreased circulating creatini... 1 | 31
decreased circulating free fat... 1 | 39
decreased circulating iron lev... 1 | 25
decreased circulating serum al... 1 | 79
decreased eosinophil cell numb... 1 | 41
decreased exploration in new e... 1 | 9
decreased fasted circulating g... 1 | 49
decreased heart rate variabili... 1 | 11
decreased mature B cell number 1 | 25
decreased threshold for audito... 1 | 32
edema 1 | 11
enlarged lymph nodes 1 | 27
enlarged spleen 1 | 26
female infertility 1 | 34
hemorrhage 1 | 12
hydrops fetalis 1 | 22
hypoactivity 1 | 89
increased blood urea nitrogen ... 1 | 44
increased body length 1 | 20
increased bone mineral content 1 | 92
increased circulating alkaline... 1 | 119
increased circulating chloride... 1 | 43
increased circulating iron lev... 1 | 25
increased circulating phosphat... 1 | 24
increased erythrocyte cell num... 1 | 26
increased exploration in new e... 1 | 56
increased grip strength 1 | 83
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased lean body mass 1 | 107
increased mean corpuscular vol... 1 | 91
increased startle reflex 1 | 38
increased total body fat amoun... 1 | 57
prenatal lethality 1 | 16
prolonged PR interval 1 | 4
respiratory system phenotype 1 | 2
short tibia 1 | 82
shortened PQ interval 1 | 6
shortened ST segment 1 | 9
tremors 1 | 34

Disease

psoriasis 101 | 6,685
ovarian cancer 86 | 8,491
glioblastoma 82 | 5,572
medulloblastoma, large-cell 77 | 6,234
lung cancer 73 | 4,473
osteosarcoma 71 | 7,933
atypical teratoid / rhabdoid tumor 61 | 4,369
Carcinoma 58 | 2,147
lung adenocarcinoma 56 | 2,714
invasive ductal carcinoma 52 | 2,950
primitive neuroectodermal tumor 51 | 3,031
acute quadriplegic myopathy 50 | 1,157
malignant mesothelioma 49 | 3,163
colon cancer 48 | 1,475
Breast cancer 47 | 3,098
non-small cell lung cancer 47 | 2,798
intraductal papillary-mucinous neoplasm (IPMN) 46 | 3,289
pancreatic cancer 46 | 2,300
pilocytic astrocytoma 46 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 45 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 45 | 2,988
lung carcinoma 45 | 2,844
pediatric high grade glioma 43 | 2,712
oligodendroglioma 39 | 2,849
Cancer 38 | 2,346
Myopathy 38 | 128
Heart disease 36 | 279
ependymoma 35 | 2,514
diabetes mellitus 34 | 1,663
Cardiomyopathy 33 | 110
subependymal giant cell astrocytoma 33 | 2,287
breast carcinoma 31 | 1,614
adult high grade glioma 30 | 2,148
astrocytic glioma 30 | 2,241
cystic fibrosis 29 | 1,670
ductal carcinoma in situ 29 | 1,745
ulcerative colitis 29 | 2,087
group 4 medulloblastoma 28 | 1,875
pituitary cancer 28 | 1,972
primary pancreatic ductal adenocarcinoma 28 | 1,271
Hypertrophic Cardiomyopathy 26 | 56
astrocytoma 26 | 1,493
tuberculosis 26 | 1,563
Dilated cardiomyopathy 25 | 51
Duchenne muscular dystrophy 24 | 602
Pick disease 24 | 1,893
medulloblastoma 24 | 1,524
Coronary artery disease 22 | 240
Familial isolated dilated cardiomyopathy 22 | 41
posterior fossa group A ependymoma 22 | 1,511
Cardiomyopathies 21 | 90
Cerebrovascular disease 21 | 231
dermatomyositis 21 | 966
adrenocortical carcinoma 20 | 1,427
Amyotrophic Lateral Sclerosis 19 | 432
group 3 medulloblastoma 19 | 2,254
Rheumatoid Arthritis 18 | 1,170
juvenile dermatomyositis 18 | 1,189
sonic hedgehog group medulloblastoma 18 | 1,482
Hypertension 17 | 293
Myocardial Infarction 17 | 126
interstitial cystitis 17 | 2,299
nasopharyngeal carcinoma 17 | 1,056
spina bifida 17 | 1,064
Cardiomyopathy, Dilated 16 | 47
Kidney disease 16 | 397
Alzheimer's disease 15 | 644
Atopic dermatitis 15 | 944
Atrial Fibrillation 15 | 110
Distal arthrogryposis 15 | 45
atypical teratoid/rhabdoid tumor 15 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 15 | 499
cutaneous lupus erythematosus 15 | 1,056
posterior fossa group B ependymoma 15 | 1,530
Cardiomyopathy, Hypertrophic, Familial 14 | 21
Nemaline myopathy 14 | 17
Obesity 14 | 616
pancreatic carcinoma 14 | 567
Epilepsy 13 | 346
esophageal adenocarcinoma 13 | 737
gastric carcinoma 13 | 832
Acute coronary syndrome 12 | 37
Amyloidosis 12 | 68
Anemia 12 | 252
Asthma 12 | 349
Kidney cancer 12 | 121
Multiple myeloma 12 | 1,327
Primary cutaneous amyloidosis 12 | 26
active ulcerative colitis 12 | 477
gastric cancer 12 | 436
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,795
Atherosclerosis 11 | 275
Becker muscular dystrophy 11 | 187
Down syndrome 11 | 548
Malignant hyperthermia 11 | 25
Neuropathy 11 | 210
Waldenstrons macroglobulinemia 11 | 764
active Crohn's disease 11 | 918
interstitial lung disease 11 | 292
Schizophrenia 10 | 503

Tissue

Cardiovascular System 202 | 17,957
Digestive Tract 202 | 18,472
Endocrine System 202 | 18,511
Female tissues 202 | 18,646
Liver and Pancreas 202 | 18,135
Male tissues 202 | 17,968
Nervous System 202 | 18,560
Skin and soft tissues 202 | 18,114
Urinary Tract 202 | 18,443
Blood and immune system 201 | 17,994
Respiratory system 201 | 17,483

Target Family

Non-IDG 147 | 11,969
Enzyme 23 | 4,146
Ion Channel 12 | 341
Kinase 8 | 634
Transcription Factor 7 | 1,400
Transporter 4 | 473
Epigenetic 1 | 242

Compartment GO Term

Contractile fiber 202 | 202
cellular_component 18,237 | 18,237
Cell 15,806 | 15,806
Cell part 15,806 | 15,806
Intracellular 13,611 | 13,611
Intracellular part 13,474 | 13,474
Organelle 12,648 | 12,648
membrane-bounded organelle 11,793 | 11,793
Intracellular organelle 11,617 | 11,617
Intracellular membrane-bounded... 10,618 | 10,618
Cytoplasm 10,352 | 10,352
Membrane 8,872 | 8,872
Organelle part 8,169 | 8,169
Intracellular organelle part 8,011 | 8,011
Cytoplasmic part 7,830 | 7,830
Nucleus 7,577 | 7,577
Membrane part 6,470 | 6,470
Cytosol 6,035 | 6,035
Plasma membrane 5,673 | 5,673
Intrinsic component of membran... 5,445 | 5,445
Integral component of membrane 5,315 | 5,315
Macromolecular complex 5,171 | 5,171
Cell periphery 5,146 | 5,146
Nucleoplasm 4,929 | 4,929
Extracellular region 4,606 | 4,606
Protein complex 4,439 | 4,439
Intracellular organelle lumen 4,330 | 4,330
Organelle lumen 4,330 | 4,330
membrane-enclosed lumen 4,330 | 4,330
Extracellular region part 3,873 | 3,873
Intracellular non-membrane-bou... 3,839 | 3,839
non-membrane-bounded organelle 3,838 | 3,838
Nuclear part 3,807 | 3,807
Endomembrane system 3,720 | 3,720
Vesicle 3,666 | 3,666
membrane-bounded vesicle 3,494 | 3,494
Nuclear lumen 3,464 | 3,464
Extracellular organelle 2,849 | 2,849
Extracellular vesicle 2,848 | 2,848
Extracellular exosome 2,828 | 2,828
Organelle membrane 2,593 | 2,593
Plasma membrane part 2,564 | 2,564
Cytoskeleton 2,046 | 2,046
Golgi apparatus 1,946 | 1,946
Endoplasmic reticulum 1,872 | 1,872
Intrinsic component of plasma ... 1,783 | 1,783
Bounding membrane of organelle 1,729 | 1,729
Integral component of plasma m... 1,723 | 1,723
Vesicles 1,625 | 1,625
Cytoskeletal part 1,568 | 1,568
Mitochondrion 1,531 | 1,531
Cell projection 1,426 | 1,426
Extracellular space 1,329 | 1,329
Whole membrane 1,320 | 1,320
GO:0098796 1,305 | 1,305
Cell junction 1,301 | 1,301
Vacuole 1,263 | 1,263
Intracellular vesicle 1,256 | 1,256
Cytoplasmic vesicle 1,255 | 1,255
Catalytic complex 1,234 | 1,234
Endoplasmic reticulum part 1,230 | 1,230
cytoplasmic, membrane-bounded ... 1,125 | 1,125
GO:0031975 1,093 | 1,093
Microtubule cytoskeleton 1,087 | 1,087
Organelle envelope 1,085 | 1,085
Nuclear outer membrane-endopla... 1,079 | 1,079
Endoplasmic reticulum membrane 1,062 | 1,062
Mitochondria 1,003 | 1,003
Chromosome 999 | 999
Mitochondrial part 989 | 989
Nucleoli 952 | 952
Golgi apparatus part 940 | 940
Neuron part 913 | 913
Chromosomal part 862 | 862
Endosome 857 | 857
Nucleolus 839 | 839
Cell surface 836 | 836
Transferase complex 816 | 816
Ribonucleoprotein complex 793 | 793
Intracellular ribonucleoprotei... 789 | 789
Nucleoplasm part 781 | 781
Plasma membrane region 777 | 777
Vacuolar part 776 | 776
Polymeric cytoskeletal fiber 758 | 758
Supramolecular fiber 758 | 758
Cell projection part 739 | 739
Plasma membrane protein comple... 721 | 721
Mitochondrial envelope 716 | 716
Golgi membrane 710 | 710
Anchoring junction 702 | 702
Adherens junction 687 | 687
Cytoplasmic vesicle part 682 | 682
Neuron projection 681 | 681
Microtubule organizing center 680 | 680
Centrosome 676 | 676
Vacuolar membrane 667 | 667
Mitochondrial membrane 663 | 663
Receptor complex 657 | 657
Extracellular matrix 633 | 633
Synapse 594 | 594
Lytic vacuole 571 | 571

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Galectin-3 LGALS3 Tchem Non-IDG -3.33005 2249.5 911
Rho guanine nucleotide exchange factor 25 ARHGEF25 Tbio Non-IDG -1.42716 30.4 46
Myosin light chain 1/3, skeletal muscle isoform MYL1 Tbio Non-IDG -2.09889 127.4 77
Maltase-glucoamylase, intestinal MGAM Tclin Enzyme -4.50018 27956.4 30
Cystatin-C CST3 Tbio Non-IDG -3.48935 3020.7 756
Tripartite motif-containing protein 54 TRIM54 Tbio Non-IDG -1.52332 39.6 218
Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C Tclin Ion Channel -2.72211 489.2 316
Twinfilin-1 TWF1 Tbio Non-IDG -1.07756 12.2 177
Cysteine and glycine-rich protein 3 CSRP3 Tbio Non-IDG -1.98408 93.8 215
Natriuretic peptides B NPPB Tbio Non-IDG -3.33533 2101.7 760