Development Level

Tbio 64 | 11,445
Tchem 8 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal retina morphology 3 | 71
abnormal bone mineralization 2 | 38
decreased circulating serum al... 2 | 82
decreased lymphocyte cell numb... 2 | 83
edema 2 | 59
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased body weight 2 | 25
increased neutrophil cell numb... 2 | 46
increased startle reflex 2 | 112
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal head morphology 1 | 10
abnormal joint morphology 1 | 23
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal placenta size 1 | 20
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal startle reflex 1 | 15
absent teeth 1 | 3
brachydactyly 1 | 19
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating potassiu... 1 | 20
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased leukocyte cell numbe... 1 | 73
decreased spleen weight 1 | 10
decreased thermal nociceptive ... 1 | 2
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged pancreas 1 | 2
eye hemorrhage 1 | 1
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating iron lev... 1 | 30
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased lean body mass 1 | 172
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
mammalian phenotype 1 | 17
mydriasis 1 | 6
polycystic kidney 1 | 15
shortened RR interval 1 | 17
syndactyly 1 | 23

Disease

Carcinoma 59 | 11,493
osteosarcoma 53 | 7,950
ovarian cancer 53 | 8,520
glioblastoma 46 | 5,792
Cancer 42 | 2,499
medulloblastoma, large-cell 39 | 6,241
psoriasis 36 | 6,694
atypical teratoid / rhabdoid tumor 34 | 5,112
ependymoma 32 | 4,679
pancreatic cancer 32 | 2,398
lung cancer 30 | 4,740
Breast cancer 28 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
adult high grade glioma 25 | 3,801
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
intraductal papillary-mucinous adenoma (IPMA) 24 | 2,955
subependymal giant cell astrocytoma 24 | 2,287
group 4 medulloblastoma 23 | 1,855
invasive ductal carcinoma 22 | 2,951
malignant mesothelioma 22 | 3,232
Astrocytoma, Pilocytic 21 | 3,081
Kidney cancer 21 | 2,613
lung carcinoma 21 | 2,843
non-small cell lung cancer 21 | 2,890
primary pancreatic ductal adenocarcinoma 19 | 1,109
primitive neuroectodermal tumor 19 | 3,035
lung adenocarcinoma 18 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 18 | 1,962
astrocytic glioma 16 | 2,597
breast carcinoma 16 | 1,638
diabetes mellitus 16 | 1,728
group 3 medulloblastoma 16 | 4,104
juvenile dermatomyositis 16 | 1,187
ulcerative colitis 16 | 1,819
adrenocortical carcinoma 15 | 1,428
colon cancer 15 | 1,478
oligodendroglioma 15 | 2,850
cystic fibrosis 14 | 1,696
interstitial cystitis 14 | 2,312
spina bifida 14 | 1,074
Neoplasm Invasiveness 13 | 161
ductal carcinoma in situ 13 | 1,745
Liver Cirrhosis, Experimental 12 | 769
Rheumatoid arthritis 12 | 1,191
acute quadriplegic myopathy 12 | 1,158
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
Duchenne muscular dystrophy 11 | 601
dermatomyositis 11 | 966
Kidney disease 10 | 430
Multiple myeloma 10 | 1,332
Pick disease 10 | 1,894
Schizophrenia 10 | 1,160
pancreatic carcinoma 10 | 562
Breast Neoplasms 9 | 445
Neoplasm Metastasis 9 | 168
Osteoporosis 9 | 363
Vascular disease 9 | 319
astrocytoma 9 | 1,146
gastric cancer 9 | 459
gastric carcinoma 9 | 807
pituitary cancer 9 | 1,972
Mammary Neoplasms 8 | 425
esophageal adenocarcinoma 8 | 737
pediatric high grade glioma 8 | 1,064
tuberculosis 8 | 2,010
Bipolar Disorder 7 | 666
Inflammatory bowel disease 7 | 151
Renal Cell Carcinoma 7 | 214
Stomach Neoplasms 7 | 300
cutaneous lupus erythematosus 7 | 1,057
hepatocellular carcinoma 7 | 547
Alzheimer's disease 6 | 658
Carcinoma, Hepatocellular 6 | 228
Carcinoma, Squamous Cell 6 | 110
Cell Transformation, Neoplastic 6 | 97
Cerebrovascular disease 6 | 238
Colorectal Neoplasms 6 | 243
Down syndrome 6 | 499
Heart disease 6 | 306
Hypertension 6 | 396
Liver carcinoma 6 | 240
Skin cancer 6 | 469
Squamous cell carcinoma 6 | 129
medulloblastoma 6 | 720
mucosa-associated lymphoid tissue lymphoma 6 | 484
Acquired scoliosis 5 | 281
Adenoma 5 | 167
Arthritis, Juvenile 5 | 126
Atopic dermatitis 5 | 952
Curvature of spine 5 | 282
Juvenile arthritis 5 | 126
Pancreatic Neoplasm 5 | 85
Pancreatic Neoplasms 5 | 85
Polycystic ovary syndrome 5 | 360
Prostatic Neoplasms 5 | 495
Waldenstrons macroglobulinemia 5 | 765
active Crohn's disease 5 | 922
active ulcerative colitis 5 | 764
aldosterone-producing adenoma 5 | 665
urothelial carcinoma 5 | 318

Tissue

Blood and immune system 74 | 16,909
Endocrine System 74 | 18,159
Cardiovascular System 73 | 15,192
Digestive Tract 73 | 17,369
Female tissues 73 | 17,400
Liver and Pancreas 73 | 16,750
Male tissues 73 | 17,142
Nervous System 73 | 16,725
Respiratory system 73 | 16,393
Skin and soft tissues 73 | 17,230
Urinary Tract 73 | 16,678

Target Family

Non-IDG 54 | 12,091
Enzyme 11 | 4,145
Kinase 7 | 634
Transcription Factor 2 | 1,400
Transporter 1 | 473

Compartment GO Term

Contractile actin filament bun... 75 | 75
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Septin-11 SEPT11 Tbio Non-IDG -1.47747 32.4 127
Tropomyosin alpha-4 chain TPM4 Tbio Non-IDG -1.57899 37.4 120
FH1/FH2 domain-containing protein 1 FHOD1 Tbio Non-IDG -1.49217 38.9 120
Palladin PALLD Tbio Non-IDG -2.73002 528.8 164
Moesin MSN Tbio Non-IDG -2.61389 361.7 550
Rhotekin RTKN Tbio Non-IDG -1.49615 24.3 137
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.26880 23.6 187
Coronin-1B CORO1B Tbio Non-IDG -1.09320 13.6 149
Disheveled-associated activator of morphogenesis 1 DAAM1 Tbio Non-IDG -1.45166 30.8 269
Rho-associated protein kinase 1 ROCK1 Tclin Kinase -2.64622 378.2 461