Development Level

Tbio 21 | 11,445
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

decreased vertical activity 3 | 208
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
hydrometra 2 | 53
increased or absent threshold ... 2 | 101
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased caudal vertebrae num... 1 | 53
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
edema 1 | 59
enlarged spleen 1 | 41
enlarged uterus 1 | 11
prenatal lethality prior to he... 1 | 87
small superior vagus ganglion 1 | 74

Disease

Carcinoma 15 | 11,493
psoriasis 12 | 6,694
osteosarcoma 11 | 7,950
ovarian cancer 10 | 8,520
Erythrokeratodermia variabilis 8 | 10
adult high grade glioma 8 | 3,801
Oculodentodigital dysplasia 7 | 14
interstitial cystitis 7 | 2,312
lung adenocarcinoma 7 | 2,716
medulloblastoma, large-cell 7 | 6,241
Cataract 6 | 297
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung cancer 6 | 4,740
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
Clouston syndrome 5 | 9
Lens Opacities 5 | 231
Nonsyndromic deafness 5 | 142
Palmoplantar keratosis 5 | 74
diabetes mellitus 5 | 1,728
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
ulcerative colitis 5 | 1,819
Alopecia 4 | 115
Autosomal recessive predisposition 4 | 1,442
Cancer 4 | 2,499
Deafness, autosomal recessive 1A 4 | 4
Erythema 4 | 58
Flushing 4 | 60
Hyperkeratosis, generalized 4 | 14
Hypertension 4 | 396
Hypertensive disease 4 | 292
Schizophrenia 4 | 1,160
Sensorineural hearing loss 4 | 106
Small head 4 | 374
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
malignant mesothelioma 4 | 3,232
pancreatic cancer 4 | 2,398
spina bifida 4 | 1,074
Astrocytoma, Pilocytic 3 | 3,081
Autistic Disorder 3 | 364
Bart-Pumphrey syndrome 3 | 4
Cerebrovascular disease 3 | 238
Charcot-Marie-Tooth disease 3 | 62
Conductive hearing loss 3 | 123
DEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder) 3 | 3
Deafness 3 | 198
Dull intelligence 3 | 645
Dystrophic fingernails 3 | 18
Enlarged vestibular aqueduct 3 | 10
Epilepsy 3 | 792
Fine hair 3 | 42
Frontal bossing 3 | 157
Infantile onset 3 | 238
Intellectual disability 3 | 1,016
Low Vision 3 | 174
Low intelligence 3 | 645
MEDNIK syndrome 3 | 8
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Myopia 3 | 176
Nail dysplasia 3 | 52
Neurodegenerative disease 3 | 414
Neuropathy 3 | 261
Nuclear cataract 3 | 19
Nuclear non-senile cataract 3 | 18
Poor school performance 3 | 645
Sensorineural Hearing Loss (disorder) 3 | 284
Short stature 3 | 531
Skin Neoplasms 3 | 69
Sparse eyelashes 3 | 31
Sparse hair 3 | 59
Thin, sparse hair 3 | 59
Visual Impairment 3 | 174
X- linked recessive 3 | 110
breast carcinoma 3 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
lung carcinoma 3 | 2,843
Absence of eyebrows 2 | 31
Aplasia/Hypoplasia of the eyebrow 2 | 31
Congenital deafness 2 | 185
Cortical white matter abnormalities seen on MRI 2 | 18
Dystrophia unguium 2 | 53
Hearing Loss, Partial 2 | 185
Keratitis 2 | 62
Leukoaraiosis 2 | 18
Photodysphoria 2 | 121
Photophobia 2 | 121
Sinoatrial node disease 2 | 5
Sparse or absent eyebrows 2 | 31
Sparse/absent eyebrows 2 | 31
Weight decreased 2 | 103
facioscapulohumeral dystrophy 2 | 288
hearing impairment 2 | 199

Tissue

Endocrine System 23 | 18,159
Female tissues 21 | 17,400
Urinary Tract 21 | 16,678
Digestive Tract 20 | 17,369
Liver and Pancreas 20 | 16,750
Nervous System 19 | 16,725
Skin and soft tissues 19 | 17,230
Blood and immune system 18 | 16,909
Male tissues 18 | 17,142
Respiratory system 17 | 16,393
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 20 | 12,091
Ion Channel 3 | 344

Compartment GO Term

Connexin complex 23 | 23
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pannexin-3 PANX3 Tbio Ion Channel -1.66465 45.0 71
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Pannexin-1 PANX1 Tbio Ion Channel -2.59888 418.5 154
Pannexin-2 PANX2 Tbio Ion Channel -1.77864 56.1 126
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Gap junction alpha-4 protein GJA4 Tbio Non-IDG -2.27043 180.6 231
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Gap junction beta-3 protein GJB3 Tbio Non-IDG -2.13572 133.9 212