Development Level

Tbio 85 | 11,445
Tdark 12 | 6,588
Tchem 9 | 1,598

IMPC Phenotype

preweaning lethality, complete... 20 | 979
cataract 4 | 92
embryonic lethality prior to o... 4 | 239
abnormal embryo size 3 | 220
abnormal lens morphology 3 | 81
abnormal tail morphology 3 | 25
embryonic lethality prior to t... 3 | 278
preweaning lethality, incomple... 3 | 499
abnormal behavior 2 | 298
abnormal seminal vesicle morph... 2 | 114
decreased circulating choleste... 2 | 93
embryonic growth retardation 2 | 106
enlarged lymph nodes 2 | 37
increased circulating HDL chol... 2 | 80
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal kidney morphology 1 | 65
abnormal lung morphology 1 | 26
abnormal motor learning 1 | 3
abnormal placenta morphology 1 | 5
abnormal placenta size 1 | 20
abnormal placenta vasculature 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal inner nuclear... 1 | 8
abnormal retinal outer nuclear... 1 | 3
abnormal skin coloration 1 | 25
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
corneal opacity 1 | 32
decreased circulating free fat... 1 | 31
decreased circulating iron lev... 1 | 32
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
edema 1 | 59
hemorrhage 1 | 23
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased or absent threshold ... 1 | 101
irregularly shaped pupil 1 | 7
microphthalmia 1 | 26
mydriasis 1 | 6
prenatal lethality prior to he... 1 | 87
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
syndactyly 1 | 23
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4

Disease

ovarian cancer 67 | 8,520
Carcinoma 63 | 11,493
group 3 medulloblastoma 61 | 4,104
medulloblastoma, large-cell 61 | 6,241
psoriasis 56 | 6,694
glioblastoma 52 | 5,792
lung cancer 52 | 4,740
atypical teratoid / rhabdoid tumor 51 | 5,112
Breast cancer 50 | 3,578
osteosarcoma 47 | 7,950
primitive neuroectodermal tumor 46 | 3,035
non-small cell lung cancer 44 | 2,890
intraductal papillary-mucinous neoplasm (IPMN) 43 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 42 | 2,989
adrenocortical carcinoma 39 | 1,428
ependymoma 38 | 4,679
invasive ductal carcinoma 34 | 2,951
lung adenocarcinoma 34 | 2,716
adult high grade glioma 33 | 3,801
malignant mesothelioma 32 | 3,232
ductal carcinoma in situ 26 | 1,745
oligodendroglioma 24 | 2,850
Endometriosis 23 | 540
colon cancer 23 | 1,478
Atopic dermatitis 21 | 952
Cancer 21 | 2,499
breast carcinoma 21 | 1,638
nasopharyngeal carcinoma 20 | 1,058
Kidney cancer 19 | 2,613
pancreatic cancer 18 | 2,398
astrocytic glioma 17 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 14 | 2,955
subependymal giant cell astrocytoma 14 | 2,287
ulcerative colitis 14 | 1,819
Astrocytoma, Pilocytic 13 | 3,081
Intellectual disability 13 | 1,016
Waldenstrons macroglobulinemia 13 | 765
Multiple myeloma 12 | 1,332
Pick disease 12 | 1,894
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
non primary Sjogren syndrome sicca 10 | 891
pediatric high grade glioma 10 | 1,064
primary Sjogren syndrome 10 | 735
dermatomyositis 9 | 966
interstitial cystitis 9 | 2,312
lung carcinoma 9 | 2,843
pituitary cancer 9 | 1,972
Cognitive delay 7 | 608
Dull intelligence 7 | 645
Global developmental delay 7 | 608
Low intelligence 7 | 645
Mental Retardation 7 | 645
Mental and motor retardation 7 | 608
Mental deficiency 7 | 645
Poor school performance 7 | 645
Small head 7 | 374
acute quadriplegic myopathy 7 | 1,158
astrocytoma 7 | 1,146
group 4 medulloblastoma 7 | 1,855
tuberculosis 7 | 2,010
Autosomal recessive predisposition 6 | 1,442
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
Short stature 6 | 531
progressive supranuclear palsy 6 | 676
Cataract 5 | 297
Epilepsy 5 | 792
Glaucoma 5 | 239
Microcephaly 5 | 166
Schizophrenia 5 | 1,160
active Crohn's disease 5 | 922
acute myeloid leukemia 5 | 783
juvenile dermatomyositis 5 | 1,187
posterior fossa group A ependymoma 5 | 468
Alzheimer's disease 4 | 658
Amyotrophic lateral sclerosis 4 | 451
Anteverted nostril 4 | 191
Bipolar Disorder 4 | 666
Cerebellar Hypoplasia 4 | 61
Epilepsies, Myoclonic 4 | 32
Fetal Growth Retardation 4 | 189
Generalized myoclonic seizures 4 | 30
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Lens Opacities 4 | 231
Myoclonic Epilepsies, Progressive 4 | 44
Rheumatoid arthritis 4 | 1,191
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis and chronic rhinosinusitis 4 | 214
gastric carcinoma 4 | 807
Congenital Epicanthus 3 | 177
Down syndrome 3 | 499
Failure to gain weight 3 | 365
Polycystic ovary syndrome 3 | 360
Seizures 3 | 596
Small nose 3 | 132
cystic fibrosis 3 | 1,696
pancreatic carcinoma 3 | 562
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 106 | 18,159
Blood and immune system 104 | 16,909
Digestive Tract 104 | 17,369
Female tissues 104 | 17,400
Liver and Pancreas 104 | 16,750
Nervous System 104 | 16,725
Respiratory system 104 | 16,393
Skin and soft tissues 104 | 17,230
Urinary Tract 104 | 16,678
Male tissues 103 | 17,142
Cardiovascular System 99 | 15,192

Target Family

Non-IDG 88 | 12,091
Kinase 7 | 634
Enzyme 4 | 4,145
Epigenetic 3 | 242
Transcription Factor 3 | 1,400
Transporter 1 | 473

Compartment GO Term

Condensed chromosome kinetocho... 106 | 106
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,109 | 14,109
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,975 | 8,975
Intracellular organelle part 8,783 | 8,783
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,933 | 1,933
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,642 | 1,642
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,628 | 1,628
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 971 | 971
Neuron part 970 | 970
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 951 | 951
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 712 | 712
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 663 | 663
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sperm-associated antigen 5 SPAG5 Tbio Non-IDG -1.72743 51.4 136
Nuclear distribution protein nudE homolog 1 NDE1 Tbio Non-IDG -2.01711 96.0 192
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Spindle and kinetochore-associated protein 2 SKA2 Tbio Non-IDG -1.23206 10.2 108
G patch domain-containing protein 11 GPATCH11 Tdark Non-IDG 0.14 0.15 105
Small kinetochore-associated protein KNSTRN Tbio Non-IDG -1.28291 21.4 32
Centromere protein K CENPK Tbio Non-IDG -1.21832 16.6 130
Heterogeneous nuclear ribonucleoprotein U HNRNPU Tbio Non-IDG -2.33813 207.8 169
TP53-binding protein 1 TP53BP1 Tbio Epigenetic -2.69485 464.8 577
Kinesin-like protein KIF2C KIF2C Tbio Non-IDG -2.12404 136.3 256