Development Level

Tbio 21 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

decreased total body fat amoun... 2 | 207
abnormal femur morphology 1 | 14
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal tail morphology 1 | 25
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
dilated heart left ventricle 1 | 11
impaired glucose tolerance 1 | 75
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 22 | 11,493
Astrocytoma, Pilocytic 18 | 3,081
ovarian cancer 18 | 8,520
lung cancer 17 | 4,740
Kidney cancer 16 | 2,613
Breast cancer 15 | 3,578
glioblastoma 15 | 5,792
adult high grade glioma 14 | 3,801
ependymoma 14 | 4,679
medulloblastoma, large-cell 14 | 6,241
psoriasis 14 | 6,694
atypical teratoid / rhabdoid tumor 12 | 5,112
interstitial cystitis 12 | 2,312
lung adenocarcinoma 12 | 2,716
malignant mesothelioma 12 | 3,232
non-small cell lung cancer 12 | 2,890
pancreatic cancer 12 | 2,398
cystic fibrosis 11 | 1,696
gastric carcinoma 11 | 807
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
pituitary cancer 11 | 1,972
Duchenne muscular dystrophy 10 | 601
Liver Cirrhosis, Experimental 10 | 769
Myopia 10 | 176
breast carcinoma 10 | 1,638
invasive ductal carcinoma 10 | 2,951
nasopharyngeal carcinoma 10 | 1,058
osteosarcoma 10 | 7,950
ulcerative colitis 10 | 1,819
urothelial carcinoma 10 | 318
Autosomal recessive predisposition 9 | 1,442
Degenerative polyarthritis 9 | 115
Melanoma 9 | 711
Short stature 9 | 531
Skin cancer 9 | 469
adrenocortical carcinoma 9 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 9 | 510
ductal carcinoma in situ 9 | 1,745
limb girdle muscular dystrophy 2A 9 | 213
primitive neuroectodermal tumor 9 | 3,035
Ehlers-Danlos syndrome 8 | 43
Osteoarthritis 8 | 184
colon cancer 8 | 1,478
esophageal adenocarcinoma 8 | 737
group 3 medulloblastoma 8 | 4,104
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Acquired scoliosis 7 | 281
Becker muscular dystrophy 7 | 191
Curvature of spine 7 | 282
Degenerative disc disease 7 | 35
Joint hyperflexibility 7 | 78
Kidney disease 7 | 430
Pick disease 7 | 1,894
Platyspondyly 7 | 56
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
juvenile dermatomyositis 7 | 1,187
oligodendroglioma 7 | 2,850
pterygium 7 | 76
Alport syndrome 6 | 21
Congenital deafness 6 | 185
Deafness 6 | 198
Hearing Loss, Partial 6 | 185
Hernia, Inguinal 6 | 89
Mitral Valve Prolapse Syndrome 6 | 39
Nephrotic Syndrome 6 | 78
Pectus excavatum 6 | 100
Thin skin 6 | 47
cutaneous lupus erythematosus 6 | 1,057
hearing impairment 6 | 199
interstitial lung disease 6 | 298
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
subependymal giant cell astrocytoma 6 | 2,287
Abortion, Spontaneous 5 | 109
Atrophic scar 5 | 18
Cataract 5 | 297
Congenital Epicanthus 5 | 177
Decreased projection of midface 5 | 105
Ecchymosis 5 | 66
Flatfoot 5 | 73
Hypertensive disease 5 | 292
Hypoplastic mandible condyle 5 | 275
Hypotrophic midface 5 | 105
Increased tendency to bruise 5 | 66
Lens Opacities 5 | 231
Liver Cirrhosis 5 | 181
Liver cancer 5 | 604
Mandibular hypoplasia 5 | 275
Micrognathism 5 | 275
Midface retrusion 5 | 105
Premature Birth 5 | 77
Premature birth of newborn 5 | 67
Respiratory Insufficiency 5 | 132
Respiratory function loss 5 | 121
Skin hyperelastic 5 | 32
Small midface 5 | 105
Soft skin 5 | 17
Spontaneous abortion 5 | 113
Velvety skin 5 | 17
lung carcinoma 5 | 2,843

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Male tissues 21 | 17,142
Urinary Tract 21 | 16,678
Blood and immune system 20 | 16,909
Liver and Pancreas 20 | 16,750
Nervous System 20 | 16,725
Respiratory system 20 | 16,393
Skin and soft tissues 20 | 17,230
Cardiovascular System 18 | 15,192

Target Family

Non-IDG 21 | 12,091
Enzyme 1 | 4,145

Compartment GO Term

Complex of collagen trimers 22 | 22
cellular_component 18,320 | 18,320
Cell 16,178 | 16,178
Cell part 16,177 | 16,177
Intracellular 14,108 | 14,108
Intracellular part 13,972 | 13,972
Organelle 12,238 | 12,238
Intracellular organelle 12,025 | 12,025
membrane-bounded organelle 11,132 | 11,132
Cytoplasm 10,983 | 10,983
Intracellular membrane-bounded... 10,341 | 10,341
Cytoplasmic part 9,247 | 9,247
Organelle part 8,976 | 8,976
Intracellular organelle part 8,784 | 8,784
Membrane 8,531 | 8,531
Nucleus 7,562 | 7,562
Cytosol 6,686 | 6,686
Membrane part 6,554 | 6,554
Plasma membrane 5,830 | 5,830
Macromolecular complex 5,475 | 5,475
Intrinsic component of membran... 5,458 | 5,458
Cell periphery 5,382 | 5,382
Integral component of membrane 5,331 | 5,331
Intracellular organelle lumen 5,090 | 5,090
Organelle lumen 5,090 | 5,090
membrane-enclosed lumen 5,090 | 5,090
Nucleoplasm 5,077 | 5,077
Nuclear part 4,290 | 4,290
Endomembrane system 4,237 | 4,237
Intracellular non-membrane-bou... 3,975 | 3,975
non-membrane-bounded organelle 3,974 | 3,974
Nuclear lumen 3,968 | 3,968
Protein complex 3,674 | 3,674
Organelle membrane 2,846 | 2,846
Extracellular region 2,732 | 2,732
Plasma membrane part 2,594 | 2,594
Vesicle 2,342 | 2,342
Cytoplasmic vesicle 2,218 | 2,218
Intracellular vesicle 2,217 | 2,217
Cytoskeleton 2,108 | 2,108
Endoplasmic reticulum 2,001 | 2,001
Bounding membrane of organelle 1,956 | 1,956
Golgi apparatus 1,932 | 1,932
Intrinsic component of plasma ... 1,749 | 1,749
Integral component of plasma m... 1,693 | 1,693
Catalytic complex 1,641 | 1,641
Cytoskeletal part 1,637 | 1,637
Extracellular region part 1,627 | 1,627
Vesicles 1,613 | 1,613
Mitochondrion 1,576 | 1,576
Whole membrane 1,548 | 1,548
Cell projection 1,541 | 1,541
Cytoplasmic vesicle part 1,513 | 1,513
Endoplasmic reticulum part 1,359 | 1,359
GO:0031975 1,150 | 1,150
Organelle envelope 1,142 | 1,142
Microtubule cytoskeleton 1,137 | 1,137
Extracellular space 1,124 | 1,124
Nucleoplasm part 1,122 | 1,122
Nuclear outer membrane-endopla... 1,121 | 1,121
Endoplasmic reticulum membrane 1,103 | 1,103
Chromosome 1,039 | 1,039
Mitochondrial part 1,036 | 1,036
Mitochondria 998 | 998
Secretory vesicle 970 | 970
Neuron part 969 | 969
Supramolecular polymer 967 | 967
Supramolecular complex 966 | 966
Cell junction 960 | 960
Supramolecular fiber 959 | 959
Golgi apparatus part 950 | 950
Nucleoli 942 | 942
Endosome 930 | 930
Nucleolus 926 | 926
Chromosomal part 889 | 889
GO:0098796 884 | 884
Ribonucleoprotein complex 865 | 865
Secretory granule 852 | 852
Cell projection part 850 | 850
Intracellular ribonucleoprotei... 850 | 850
Transferase complex 849 | 849
Cell surface 842 | 842
Plasma membrane region 841 | 841
Vesicle membrane 801 | 801
Cytoplasmic vesicle membrane 795 | 795
Polymeric cytoskeletal fiber 764 | 764
Mitochondrial envelope 746 | 746
Vacuole 732 | 732
Nuclear body 725 | 725
Golgi membrane 724 | 724
Microtubule organizing center 721 | 721
Extracellular matrix 714 | 714
Neuron projection 711 | 711
Centrosome 696 | 696
Mitochondrial membrane 696 | 696
Receptor complex 686 | 686
Synapse 662 | 662
Lysosome 624 | 624
Lytic vacuole 624 | 624
Chromatin 565 | 565
Endosomal part 565 | 565

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Aggrecan core protein ACAN Tbio Non-IDG -3.36238 2138.5 0
Collagenase 3 MMP13 Tchem Enzyme -3.12173 1243.8 772
Decorin DCN Tbio Non-IDG -3.05208 1155.4 480
Collagen alpha-1(I) chain COL1A1 Tbio Non-IDG -2.98303 874.8 508
Collagen alpha-1(II) chain COL2A1 Tbio Non-IDG -2.89229 724.4 424
Biglycan BGN Tbio Non-IDG -2.73039 529.9 267
Lumican LUM Tbio Non-IDG -2.72477 535.8 237
Collagen alpha-2(I) chain COL1A2 Tbio Non-IDG -2.64284 404.0 258
Collagen alpha-1(III) chain COL3A1 Tbio Non-IDG -2.58251 354.8 439
Collagen alpha-1(VII) chain COL7A1 Tbio Non-IDG -2.58130 371.7 95